Versatile Cataract Fundus Image Restoration Model Utilizing Unpaired Cataract and High-quality Images

Cataract is one of the most common blinding eye diseases and can be treated by surgery. However, because cataract patients may also suffer from other blinding eye diseases, ophthalmologists must diagnose them before surgery. The cloudy lens of cataract patients forms a hazy degeneration in the fundus images, making it challenging to observe the patient's fundus vessels, which brings difficulties to the diagnosis process. To address this issue, this paper establishes a new cataract image restoration method named Catintell. It contains a cataract image synthesizing model, Catintell-Syn, and a restoration model, Catintell-Res. Catintell-Syn uses GAN architecture with fully unsupervised data to generate paired cataract-like images with realistic style and texture rather than the conventional Gaussian degradation algorithm. Meanwhile, Catintell-Res is an image restoration network that can improve the quality of real cataract fundus images using the knowledge learned from synthetic cataract images. Extensive experiments show that Catintell-Res outperforms other cataract image restoration methods in PSNR with 39.03 and SSIM with 0.9476. Furthermore, the universal restoration ability that Catintell-Res gained from unpaired cataract images can process cataract images from various datasets. We hope the models can help ophthalmologists identify other blinding eye diseases of cataract patients and inspire more medical image restoration methods in the future.

Acquire Precise and Comparable Fundus Image Quality Score: FTHNet and FQS Dataset

The retinal fundus images are utilized extensively in the diagnosis, and their quality can directly affect the diagnosis results. However, due to the insufficient dataset and algorithm application, current fundus image quality assessment (FIQA) methods are not powerful enough to meet ophthalmologists` demands. In this paper, we address the limitations of datasets and algorithms in FIQA. First, we establish a new FIQA dataset, Fundus Quality Score(FQS), which includes 2246 fundus images with two labels: a continuous Mean Opinion Score varying from 0 to 100 and a three-level quality label. Then, we propose a FIQA Transformer-based Hypernetwork (FTHNet) to solve these tasks with regression results rather than classification results in conventional FIQA works. The FTHNet is optimized for the FIQA tasks with extensive experiments. Results on our FQS dataset show that the FTHNet can give quality scores for fundus images with PLCC of 0.9423 and SRCC of 0.9488, significantly outperforming other methods with fewer parameters and less computation complexity.We successfully build a dataset and model addressing the problems of current FIQA methods. Furthermore, the model deployment experiments demonstrate its potential in automatic medical image quality control. All experiments are carried out with 10-fold cross-validation to ensure the significance of the results.

TabKANet: Tabular Data Modelling with Kolmogorov-Arnold Network and Transformer

Tabular data is the most common type of data in real-life scenarios. In this study, we propose a method based on the TabKANet architecture, which utilizes the Kolmogorov-Arnold network to encode numerical features and merge them with categorical features, enabling unified modeling of tabular data on the Transformer architecture. This model demonstrates outstanding performance in six widely used binary classification tasks, suggesting that TabKANet has the potential to become a standard approach for tabular modeling, surpassing traditional neural networks. Furthermore, this research reveals the significant advantages of the Kolmogorov-Arnold network in encoding numerical features. The code of our work is available at https://github.com/tsinghuamedgao20/TabKANet.

Learning-based Traversability Costmap for Autonomous Off-road Navigation

Traversability estimation in off-road terrains is an essential procedure for autonomous navigation. However, creating reliable labels for complex interactions between the robot and the surface is still a challenging problem in learning-based costmap generation. To address this, we propose a method that predicts traversability costmaps by leveraging both visual and geometric information of the environment. To quantify the surface properties like roughness and bumpiness, we introduce a novel way of risk-aware labelling with proprioceptive information for network training. We validate our method in costmap prediction and navigation tasks for complex off-road scenarios. Our results demonstrate that our costmap prediction method excels in terms of average accuracy and MSE. The navigation results indicate that using our learned costmaps leads to safer and smoother driving, outperforming previous methods in terms of the highest success rate, lowest normalized trajectory length, lowest time cost, and highest mean stability across two scenarios.

Parameterized Fast and Safe Tracking (FaSTrack) using Deepreach

Fast and Safe Tracking (FaSTrack) is a modular framework that provides safety guarantees while planning and executing trajectories in real time via value functions of Hamilton-Jacobi (HJ) reachability. These value functions are computed through dynamic programming, which is notorious for being computationally inefficient. Moreover, the resulting trajectory does not adapt online to the environment, such as sudden disturbances or obstacles. DeepReach is a scalable deep learning method to HJ reachability that allows parameterization of states, which opens up possibilities for online adaptation to various controls and disturbances. In this paper, we propose Parametric FaSTrack, which uses DeepReach to approximate a value function that parameterizes the control bounds of the planning model. The new framework can smoothly trade off between the navigation speed and the tracking error (therefore maneuverability) while guaranteeing obstacle avoidance in a priori unknown environments. We demonstrate our method through two examples and a benchmark comparison with existing methods, showing the safety, efficiency, and faster solution times of the framework.

Safe Returning FaSTrack with Robust Control Lyapunov-Value Functions

Real-time navigation in a priori unknown environment remains a challenging task, especially when an unexpected (unmodeled) disturbance occurs. In this paper, we propose the framework Safe Returning Fast and Safe Tracking (SR-F) that merges concepts from 1) Robust Control Lyapunov-Value Functions (R-CLVF), and 2) the Fast and Safe Tracking (FaSTrack) framework. The SR-F computes an R-CLVF offline between a model of the true system and a simplified planning model. Online, a planning algorithm is used to generate a trajectory in the simplified planning space, and the R-CLVF is used to provide a tracking controller that exponentially stabilizes to the planning model. When an unexpected disturbance occurs, the proposed SR-F algorithm provides a means for the true system to recover to the planning model. We take advantage of this mechanism to induce an artificial disturbance by ``jumping'' the planning model in open environments, forcing faster navigation. Therefore, this algorithm can both reject unexpected true disturbances and accelerate navigation speed. We validate our framework using a 10D quadrotor system and show that SR-F is empirically 20\% faster than the original FaSTrack while maintaining safety.

Iterative Reachability Estimation for Safe Reinforcement Learning

Ensuring safety is important for the practical deployment of reinforcement learning (RL). Various challenges must be addressed, such as handling stochasticity in the environments, providing rigorous guarantees of persistent state-wise safety satisfaction, and avoiding overly conservative behaviors that sacrifice performance. We propose a new framework, Reachability Estimation for Safe Policy Optimization (RESPO), for safety-constrained RL in general stochastic settings. In the feasible set where there exist violation-free policies, we optimize for rewards while maintaining persistent safety. Outside this feasible set, our optimization produces the safest behavior by guaranteeing entrance into the feasible set whenever possible with the least cumulative discounted violations. We introduce a class of algorithms using our novel reachability estimation function to optimize in our proposed framework and in similar frameworks such as those concurrently handling multiple hard and soft constraints. We theoretically establish that our algorithms almost surely converge to locally optimal policies of our safe optimization framework. We evaluate the proposed methods on a diverse suite of safe RL environments from Safety Gym, PyBullet, and MuJoCo, and show the benefits in improving both reward performance and safety compared with state-of-the-art baselines.

Multi-Dimensional Ability Diagnosis for Machine Learning Algorithms

Machine learning algorithms have become ubiquitous in a number of applications (e.g. image classification). However, due to the insufficient measurement of traditional metrics (e.g. the coarse-grained Accuracy of each classifier), substantial gaps are usually observed between the real-world performance of these algorithms and their scores in standardized evaluations. In this paper, inspired by the psychometric theories from human measurement, we propose a task-agnostic evaluation framework Camilla, where a multi-dimensional diagnostic metric Ability is defined for collaboratively measuring the multifaceted strength of each machine learning algorithm. Specifically, given the response logs from different algorithms to data samples, we leverage cognitive diagnosis assumptions and neural networks to learn the complex interactions among algorithms, samples and the skills (explicitly or implicitly pre-defined) of each sample. In this way, both the abilities of each algorithm on multiple skills and some of the sample factors (e.g. sample difficulty) can be simultaneously quantified. We conduct extensive experiments with hundreds of machine learning algorithms on four public datasets, and our experimental results demonstrate that Camilla not only can capture the pros and cons of each algorithm more precisely, but also outperforms state-of-the-art baselines on the metric reliability, rank consistency and rank stability.

OphGLM: Training an Ophthalmology Large Language-and-Vision Assistant based on Instructions and Dialogue

Large multimodal language models (LMMs) have achieved significant success in general domains. However, due to the significant differences between medical images and text and general web content, the performance of LMMs in medical scenarios is limited. In ophthalmology, clinical diagnosis relies on multiple modalities of medical images, but unfortunately, multimodal ophthalmic large language models have not been explored to date. In this paper, we study and construct an ophthalmic large multimodal model. Firstly, we use fundus images as an entry point to build a disease assessment and diagnosis pipeline to achieve common ophthalmic disease diagnosis and lesion segmentation. Then, we establish a new ophthalmic multimodal instruction-following and dialogue fine-tuning dataset based on disease-related knowledge data and publicly available real-world medical dialogue. We introduce visual ability into the large language model to complete the ophthalmic large language and vision assistant (OphGLM). Our experimental results demonstrate that the OphGLM model performs exceptionally well, and it has the potential to revolutionize clinical applications in ophthalmology. The dataset, code, and models will be made publicly available at https://github.com/ML-AILab/OphGLM.

JiuZhang 2.0: A Unified Chinese Pre-trained Language Model for Multi-task Mathematical Problem Solving

Although pre-trained language models~(PLMs) have recently advanced the research progress in mathematical reasoning, they are not specially designed as a capable multi-task solver, suffering from high cost for multi-task deployment (\eg a model copy for a task) and inferior performance on complex mathematical problems in practical applications. To address these issues, in this paper, we propose \textbf{JiuZhang~2.0}, a unified Chinese PLM specially for multi-task mathematical problem solving. Our idea is to maintain a moderate-sized model and employ the \emph{cross-task knowledge sharing} to improve the model capacity in a multi-task setting. Specially, we construct a Mixture-of-Experts~(MoE) architecture for modeling mathematical text, so as to capture the common mathematical knowledge across tasks. For optimizing the MoE architecture, we design \emph{multi-task continual pre-training} and \emph{multi-task fine-tuning} strategies for multi-task adaptation. These training strategies can effectively decompose the knowledge from the task data and establish the cross-task sharing via expert networks. In order to further improve the general capacity of solving different complex tasks, we leverage large language models~(LLMs) as complementary models to iteratively refine the generated solution by our PLM, via in-context learning. Extensive experiments have demonstrated the effectiveness of our model.