Implementing Trust in Non-Small Cell Lung Cancer Diagnosis with a Conformalized Uncertainty-Aware AI Framework in Whole-Slide Images

Ensuring trustworthiness is fundamental to the development of artificial intelligence (AI) that is considered societally responsible, particularly in cancer diagnostics, where a misdiagnosis can have dire consequences. Current digital pathology AI models lack systematic solutions to address trustworthiness concerns arising from model limitations and data discrepancies between model deployment and development environments. To address this issue, we developed TRUECAM, a framework designed to ensure both data and model trustworthiness in non-small cell lung cancer subtyping with whole-slide images. TRUECAM integrates 1) a spectral-normalized neural Gaussian process for identifying out-of-scope inputs and 2) an ambiguity-guided elimination of tiles to filter out highly ambiguous regions, addressing data trustworthiness, as well as 3) conformal prediction to ensure controlled error rates. We systematically evaluated the framework across multiple large-scale cancer datasets, leveraging both task-specific and foundation models, illustrate that an AI model wrapped with TRUECAM significantly outperforms models that lack such guidance, in terms of classification accuracy, robustness, interpretability, and data efficiency, while also achieving improvements in fairness. These findings highlight TRUECAM as a versatile wrapper framework for digital pathology AI models with diverse architectural designs, promoting their responsible and effective applications in real-world settings.

Do You Know What You Are Talking About? Characterizing Query-Knowledge Relevance For Reliable Retrieval Augmented Generation

Language models (LMs) are known to suffer from hallucinations and misinformation. Retrieval augmented generation (RAG) that retrieves verifiable information from an external knowledge corpus to complement the parametric knowledge in LMs provides a tangible solution to these problems. However, the generation quality of RAG is highly dependent on the relevance between a user's query and the retrieved documents. Inaccurate responses may be generated when the query is outside of the scope of knowledge represented in the external knowledge corpus or if the information in the corpus is out-of-date. In this work, we establish a statistical framework that assesses how well a query can be answered by an RAG system by capturing the relevance of knowledge. We introduce an online testing procedure that employs goodness-of-fit (GoF) tests to inspect the relevance of each user query to detect out-of-knowledge queries with low knowledge relevance. Additionally, we develop an offline testing framework that examines a collection of user queries, aiming to detect significant shifts in the query distribution which indicates the knowledge corpus is no longer sufficiently capable of supporting the interests of the users. We demonstrate the capabilities of these strategies through a systematic evaluation on eight question-answering (QA) datasets, the results of which indicate that the new testing framework is an efficient solution to enhance the reliability of existing RAG systems.

AlignedKV: Reducing Memory Access of KV-Cache with Precision-Aligned Quantization

Model quantization has become a crucial technique to address the issues of large memory consumption and long inference times associated with LLMs. Mixed-precision quantization, which distinguishes between important and unimportant parameters, stands out among numerous quantization schemes as it achieves a balance between precision and compression rate. However, existing approaches can only identify important parameters through qualitative analysis and manual experiments without quantitatively analyzing how their importance is determined. We propose a new criterion, so-called 'precision alignment', to build a quantitative framework to holistically evaluate the importance of parameters in mixed-precision quantization. Our observations on floating point addition under various real-world scenarios suggest that two addends should have identical precision, otherwise the information in the higher-precision number will be wasted. Such an observation offers an essential principle to determine the precision of each parameter in matrix multiplication operation. As the first step towards applying the above discovery to large model inference, we develop a dynamic KV-Cache quantization technique to effectively reduce memory access latency. Different from existing quantization approaches that focus on memory saving, this work directly aims to accelerate LLM inference through quantifying floating numbers. The proposed technique attains a 25% saving of memory access and delivers up to 1.3x speedup in the computation of attention in the decoding phase of LLM, with almost no loss of precision.

Predicting Stock Prices with FinBERT-LSTM: Integrating News Sentiment Analysis

The stock market's ascent typically mirrors the flourishing state of the economy, whereas its decline is often an indicator of an economic downturn. Therefore, for a long time, significant correlation elements for predicting trends in financial stock markets have been widely discussed, and people are becoming increasingly interested in the task of financial text mining. The inherent instability of stock prices makes them acutely responsive to fluctuations within the financial markets. In this article, we use deep learning networks, based on the history of stock prices and articles of financial, business, technical news that introduce market information to predict stock prices. We illustrate the enhancement of predictive precision by integrating weighted news categories into the forecasting model. We developed a pre-trained NLP model known as FinBERT, designed to discern the sentiments within financial texts. Subsequently, we advanced this model by incorporating the sophisticated Long Short Term Memory (LSTM) architecture, thus constructing the innovative FinBERT-LSTM model. This model utilizes news categories related to the stock market structure hierarchy, namely market, industry, and stock related news categories, combined with the stock market's stock price situation in the previous week for prediction. We selected NASDAQ-100 index stock data and trained the model on Benzinga news articles, and utilized Mean Absolute Error (MAE), Mean Absolute Percentage Error (MAPE), and Accuracy as the key metrics for the assessment and comparative analysis of the model's performance. The results indicate that FinBERT-LSTM performs the best, followed by LSTM, and DNN model ranks third in terms of effectiveness.

Adaptive Modality Balanced Online Knowledge Distillation for Brain-Eye-Computer based Dim Object Detection

Advanced cognition can be extracted from the human brain using brain-computer interfaces. Integrating these interfaces with computer vision techniques, which possess efficient feature extraction capabilities, can achieve more robust and accurate detection of dim targets in aerial images. However, existing target detection methods primarily concentrate on homogeneous data, lacking efficient and versatile processing capabilities for heterogeneous multimodal data. In this paper, we first build a brain-eye-computer based object detection system for aerial images under few-shot conditions. This system detects suspicious targets using region proposal networks, evokes the event-related potential (ERP) signal in electroencephalogram (EEG) through the eye-tracking-based slow serial visual presentation (ESSVP) paradigm, and constructs the EEG-image data pairs with eye movement data. Then, an adaptive modality balanced online knowledge distillation (AMBOKD) method is proposed to recognize dim objects with the EEG-image data. AMBOKD fuses EEG and image features using a multi-head attention module, establishing a new modality with comprehensive features. To enhance the performance and robust capability of the fusion modality, simultaneous training and mutual learning between modalities are enabled by end-to-end online knowledge distillation. During the learning process, an adaptive modality balancing module is proposed to ensure multimodal equilibrium by dynamically adjusting the weights of the importance and the training gradients across various modalities. The effectiveness and superiority of our method are demonstrated by comparing it with existing state-of-the-art methods. Additionally, experiments conducted on public datasets and system validations in real-world scenarios demonstrate the reliability and practicality of the proposed system and the designed method.

Transferable speech-to-text large language model alignment module

By leveraging the power of Large Language Models(LLMs) and speech foundation models, state of the art speech-text bimodal works can achieve challenging tasks like spoken translation(ST) and question answering(SQA) altogether with much simpler architectures. In this paper, we utilize the capability of Whisper encoder and pre-trained Yi-6B. Empirical results reveal that modal alignment can be achieved with one layer module and hundred hours of speech-text multitask corpus. We further swap the Yi-6B with human preferences aligned version of Yi-6B-Chat during inference, and discover that the alignment capability is applicable as well. In addition, the alignment subspace revealed by singular value decomposition(SVD) also implies linear alignment subspace is sparse, which leaves the possibility to concatenate other features like voice-print or video to expand modality.

AD-Aligning: Emulating Human-like Generalization for Cognitive Domain Adaptation in Deep Learning

Domain adaptation is pivotal for enabling deep learning models to generalize across diverse domains, a task complicated by variations in presentation and cognitive nuances. In this paper, we introduce AD-Aligning, a novel approach that combines adversarial training with source-target domain alignment to enhance generalization capabilities. By pretraining with Coral loss and standard loss, AD-Aligning aligns target domain statistics with those of the pretrained encoder, preserving robustness while accommodating domain shifts. Through extensive experiments on diverse datasets and domain shift scenarios, including noise-induced shifts and cognitive domain adaptation tasks, we demonstrate AD-Aligning's superior performance compared to existing methods such as Deep Coral and ADDA. Our findings highlight AD-Aligning's ability to emulate the nuanced cognitive processes inherent in human perception, making it a promising solution for real-world applications requiring adaptable and robust domain adaptation strategies.

Predicting NVIDIA's Next-Day Stock Price: A Comparative Analysis of LSTM, MLP, ARIMA, and ARIMA-GARCH Models

Forecasting stock prices remains a considerable challenge in financial markets, bearing significant implications for investors, traders, and financial institutions. Amid the ongoing AI revolution, NVIDIA has emerged as a key player driving innovation across various sectors. Given its prominence, we chose NVIDIA as the subject of our study.

Optimizing Contrail Detection: A Deep Learning Approach with EfficientNet-b4 Encoding

In the pursuit of environmental sustainability, the aviation industry faces the challenge of minimizing its ecological footprint. Among the key solutions is contrail avoidance, targeting the linear ice-crystal clouds produced by aircraft exhaust. These contrails exacerbate global warming by trapping atmospheric heat, necessitating precise segmentation and comprehensive analysis of contrail images to gauge their environmental impact. However, this segmentation task is complex due to the varying appearances of contrails under different atmospheric conditions and potential misalignment issues in predictive modeling. This paper presents an innovative deep-learning approach utilizing the efficient net-b4 encoder for feature extraction, seamlessly integrating misalignment correction, soft labeling, and pseudo-labeling techniques to enhance the accuracy and efficiency of contrail detection in satellite imagery. The proposed methodology aims to redefine contrail image analysis and contribute to the objectives of sustainable aviation by providing a robust framework for precise contrail detection and analysis in satellite imagery, thus aiding in the mitigation of aviation's environmental impact.

MP-MVS: Multi-Scale Windows PatchMatch and Planar Prior Multi-View Stereo

Significant strides have been made in enhancing the accuracy of Multi-View Stereo (MVS)-based 3D reconstruction. However, untextured areas with unstable photometric consistency often remain incompletely reconstructed. In this paper, we propose a resilient and effective multi-view stereo approach (MP-MVS). We design a multi-scale windows PatchMatch (mPM) to obtain reliable depth of untextured areas. In contrast with other multi-scale approaches, which is faster and can be easily extended to PatchMatch-based MVS approaches. Subsequently, we improve the existing checkerboard sampling schemes by limiting our sampling to distant regions, which can effectively improve the efficiency of spatial propagation while mitigating outlier generation. Finally, we introduce and improve planar prior assisted PatchMatch of ACMP. Instead of relying on photometric consistency, we utilize geometric consistency information between multi-views to select reliable triangulated vertices. This strategy can obtain a more accurate planar prior model to rectify photometric consistency measurements. Our approach has been tested on the ETH3D High-res multi-view benchmark with several state-of-the-art approaches. The results demonstrate that our approach can reach the state-of-the-art. The associated codes will be accessible at https://github.com/RongxuanTan/MP-MVS.