A Predefined-Time Convergent and Noise-Tolerant Zeroing Neural Network Model for Time Variant Quadratic Programming With Application to Robot Motion Planning

This paper develops a predefined-time convergent and noise-tolerant fractional-order zeroing neural network (PTC-NT-FOZNN) model, innovatively engineered to tackle time-variant quadratic programming (TVQP) challenges. The PTC-NT-FOZNN, stemming from a novel iteration within the variable-gain ZNN spectrum, known as FOZNNs, features diminishing gains over time and marries noise resistance with predefined-time convergence, making it ideal for energy-efficient robotic motion planning tasks. The PTC-NT-FOZNN enhances traditional ZNN models by incorporating a newly developed activation function that promotes optimal convergence irrespective of the model's order. When evaluated against six established ZNNs, the PTC-NT-FOZNN, with parameters $0 < \alpha \leq 1$, demonstrates enhanced positional precision and resilience to additive noises, making it exceptionally suitable for TVQP tasks. Thorough practical assessments, including simulations and experiments using a Flexiv Rizon robotic arm, confirm the PTC-NT-FOZNN's capabilities in achieving precise tracking and high computational efficiency, thereby proving its effectiveness for robust kinematic control applications.

COMO: Cross-Mamba Interaction and Offset-Guided Fusion for Multimodal Object Detection

Single-modal object detection tasks often experience performance degradation when encountering diverse scenarios. In contrast, multimodal object detection tasks can offer more comprehensive information about object features by integrating data from various modalities. Current multimodal object detection methods generally use various fusion techniques, including conventional neural networks and transformer-based models, to implement feature fusion strategies and achieve complementary information. However, since multimodal images are captured by different sensors, there are often misalignments between them, making direct matching challenging. This misalignment hinders the ability to establish strong correlations for the same object across different modalities. In this paper, we propose a novel approach called the CrOss-Mamba interaction and Offset-guided fusion (COMO) framework for multimodal object detection tasks. The COMO framework employs the cross-mamba technique to formulate feature interaction equations, enabling multimodal serialized state computation. This results in interactive fusion outputs while reducing computational overhead and improving efficiency. Additionally, COMO leverages high-level features, which are less affected by misalignment, to facilitate interaction and transfer complementary information between modalities, addressing the positional offset challenges caused by variations in camera angles and capture times. Furthermore, COMO incorporates a global and local scanning mechanism in the cross-mamba module to capture features with local correlation, particularly in remote sensing images. To preserve low-level features, the offset-guided fusion mechanism ensures effective multiscale feature utilization, allowing the construction of a multiscale fusion data cube that enhances detection performance.

A CT-guided Control Framework of a Robotic Flexible Endoscope for the Diagnosis of the Maxillary Sinusitis

Flexible endoscopes are commonly adopted in narrow and confined anatomical cavities due to their higher reachability and dexterity. However, prolonged and unintuitive manipulation of these endoscopes leads to an increased workload on surgeons and risks of collision. To address these challenges, this paper proposes a CT-guided control framework for the diagnosis of maxillary sinusitis by using a robotic flexible endoscope. In the CT-guided control framework, a feasible path to the target position in the maxillary sinus cavity for the robotic flexible endoscope is designed. Besides, an optimal control scheme is proposed to autonomously control the robotic flexible endoscope to follow the feasible path. This greatly improves the efficiency and reduces the workload for surgeons. Several experiments were conducted based on a widely utilized sinus phantom, and the results showed that the robotic flexible endoscope can accurately and autonomously follow the feasible path and reach the target position in the maxillary sinus cavity. The results also verified the feasibility of the CT-guided control framework, which contributes an effective approach to early diagnosis of sinusitis in the future.

Mesa-Extrapolation: A Weave Position Encoding Method for Enhanced Extrapolation in LLMs

Large language models (LLMs), although having revolutionized many fields, still suffer from the challenging extrapolation problem, where the inference ability of LLMs sharply declines beyond their max training lengths. In this work, we conduct a theoretical analysis to better understand why No Position Encoding (NoPE) fails outside its effective range, as well as examining the power of Position Encoding (PE) in this context. Our findings reveal that with meticulous weave position, PE can indeed be extended beyond effective range. Our theorems establish that LLMs equipped with weave PE can achieve improved extrapolation performance without additional cost. Furthermore, we introduce a novel weave PE method, Mesa-Extrapolation, which utilizes a chunk-based triangular attention matrix and applies Stair PE to manage the final chunk. This method not only retains competitive performance but also offers substantial benefits such as significantly reduced memory demand and faster inference speed. Extensive experiments validate the effectiveness of Mesa-Extrapolation, demonstrating its potential as a scalable solution to enhancing LLMs applicative reach.

AutoFPDesigner: Automated Flight Procedure Design Based on Multi-Agent Large Language Model

Current flight procedure design methods heavily rely on human-led design process, which is not only low auto-mation but also suffer from complex algorithm modelling and poor generalization. To address these challenges, this paper proposes an agent-driven flight procedure design method based on large language model, named Au-toFPDesigner, which utilizes multi-agent collaboration to complete procedure design. The method enables end-to-end automated design of performance-based navigation (PBN) procedures. In this process, the user input the design requirements in natural language, AutoFPDesigner models the flight procedure design by loading the design speci-fications and utilizing tool libraries complete the design. AutoFPDesigner allows users to oversee and seamlessly participate in the design process. Experimental results show that AutoFPDesigner ensures nearly 100% safety in the designed flight procedures and achieves 75% task completion rate, with good adaptability across different design tasks. AutoFPDesigner introduces a new paradigm for flight procedure design and represents a key step towards the automation of this process. Keywords: Flight Procedure Design; Large Language Model; Performance-Based Navigation (PBN); Multi Agent;

AIPatient: Simulating Patients with EHRs and LLM Powered Agentic Workflow

Simulated patient systems play a crucial role in modern medical education and research, providing safe, integrative learning environments and enabling clinical decision-making simulations. Large Language Models (LLM) could advance simulated patient systems by replicating medical conditions and patient-doctor interactions with high fidelity and low cost. However, ensuring the effectiveness and trustworthiness of these systems remains a challenge, as they require a large, diverse, and precise patient knowledgebase, along with a robust and stable knowledge diffusion to users. Here, we developed AIPatient, an advanced simulated patient system with AIPatient Knowledge Graph (AIPatient KG) as the input and the Reasoning Retrieval-Augmented Generation (Reasoning RAG) agentic workflow as the generation backbone. AIPatient KG samples data from Electronic Health Records (EHRs) in the Medical Information Mart for Intensive Care (MIMIC)-III database, producing a clinically diverse and relevant cohort of 1,495 patients with high knowledgebase validity (F1 0.89). Reasoning RAG leverages six LLM powered agents spanning tasks including retrieval, KG query generation, abstraction, checker, rewrite, and summarization. This agentic framework reaches an overall accuracy of 94.15% in EHR-based medical Question Answering (QA), outperforming benchmarks that use either no agent or only partial agent integration. Our system also presents high readability (median Flesch Reading Ease 77.23; median Flesch Kincaid Grade 5.6), robustness (ANOVA F-value 0.6126, p<0.1), and stability (ANOVA F-value 0.782, p<0.1). The promising performance of the AIPatient system highlights its potential to support a wide range of applications, including medical education, model evaluation, and system integration.

A multi-source data power load forecasting method using attention mechanism-based parallel cnn-gru

Accurate power load forecasting is crucial for improving energy efficiency and ensuring power supply quality. Considering the power load forecasting problem involves not only dynamic factors like historical load variations but also static factors such as climate conditions that remain constant over specific periods. From the model-agnostic perspective, this paper proposes a parallel structure network to extract important information from both dynamic and static data. Firstly, based on complexity learning theory, it is demonstrated that models integrated through parallel structures exhibit superior generalization abilities compared to individual base learners. Additionally, the higher the independence between base learners, the stronger the generalization ability of the parallel structure model. This suggests that the structure of machine learning models inherently contains significant information. Building on this theoretical foundation, a parallel convolutional neural network (CNN)-gate recurrent unit (GRU) attention model (PCGA) is employed to address the power load forecasting issue, aiming to effectively integrate the influences of dynamic and static features. The CNN module is responsible for capturing spatial characteristics from static data, while the GRU module captures long-term dependencies in dynamic time series data. The attention layer is designed to focus on key information from the spatial-temporal features extracted by the parallel CNN-GRU. To substantiate the advantages of the parallel structure model in extracting and integrating multi-source information, a series of experiments are conducted.

Enhancing Autism Spectrum Disorder Early Detection with the Parent-Child Dyads Block-Play Protocol and an Attention-enhanced GCN-xLSTM Hybrid Deep Learning Framework

Autism Spectrum Disorder (ASD) is a rapidly growing neurodevelopmental disorder. Performing a timely intervention is crucial for the growth of young children with ASD, but traditional clinical screening methods lack objectivity. This study introduces an innovative approach to early detection of ASD. The contributions are threefold. First, this work proposes a novel Parent-Child Dyads Block-Play (PCB) protocol, grounded in kinesiological and neuroscientific research, to identify behavioral patterns distinguishing ASD from typically developing (TD) toddlers. Second, we have compiled a substantial video dataset, featuring 40 ASD and 89 TD toddlers engaged in block play with parents. This dataset exceeds previous efforts on both the scale of participants and the length of individual sessions. Third, our approach to action analysis in videos employs a hybrid deep learning framework, integrating a two-stream graph convolution network with attention-enhanced xLSTM (2sGCN-AxLSTM). This framework is adept at capturing dynamic interactions between toddlers and parents by extracting spatial features correlated with upper body and head movements and focusing on global contextual information of action sequences over time. By learning these global features with spatio-temporal correlations, our 2sGCN-AxLSTM effectively analyzes dynamic human behavior patterns and demonstrates an unprecedented accuracy of 89.6\% in early detection of ASD. Our approach shows strong potential for enhancing early ASD diagnosis by accurately analyzing parent-child interactions, providing a critical tool to support timely and informed clinical decision-making.

Cinemo: Consistent and Controllable Image Animation with Motion Diffusion Models

Diffusion models have achieved great progress in image animation due to powerful generative capabilities. However, maintaining spatio-temporal consistency with detailed information from the input static image over time (e.g., style, background, and object of the input static image) and ensuring smoothness in animated video narratives guided by textual prompts still remains challenging. In this paper, we introduce Cinemo, a novel image animation approach towards achieving better motion controllability, as well as stronger temporal consistency and smoothness. In general, we propose three effective strategies at the training and inference stages of Cinemo to accomplish our goal. At the training stage, Cinemo focuses on learning the distribution of motion residuals, rather than directly predicting subsequent via a motion diffusion model. Additionally, a structural similarity index-based strategy is proposed to enable Cinemo to have better controllability of motion intensity. At the inference stage, a noise refinement technique based on discrete cosine transformation is introduced to mitigate sudden motion changes. Such three strategies enable Cinemo to produce highly consistent, smooth, and motion-controllable results. Compared to previous methods, Cinemo offers simpler and more precise user controllability. Extensive experiments against several state-of-the-art methods, including both commercial tools and research approaches, across multiple metrics, demonstrate the effectiveness and superiority of our proposed approach.

TCMBench: A Comprehensive Benchmark for Evaluating Large Language Models in Traditional Chinese Medicine

Large language models (LLMs) have performed remarkably well in various natural language processing tasks by benchmarking, including in the Western medical domain. However, the professional evaluation benchmarks for LLMs have yet to be covered in the traditional Chinese medicine(TCM) domain, which has a profound history and vast influence. To address this research gap, we introduce TCM-Bench, an comprehensive benchmark for evaluating LLM performance in TCM. It comprises the TCM-ED dataset, consisting of 5,473 questions sourced from the TCM Licensing Exam (TCMLE), including 1,300 questions with authoritative analysis. It covers the core components of TCMLE, including TCM basis and clinical practice. To evaluate LLMs beyond accuracy of question answering, we propose TCMScore, a metric tailored for evaluating the quality of answers generated by LLMs for TCM related questions. It comprehensively considers the consistency of TCM semantics and knowledge. After conducting comprehensive experimental analyses from diverse perspectives, we can obtain the following findings: (1) The unsatisfactory performance of LLMs on this benchmark underscores their significant room for improvement in TCM. (2) Introducing domain knowledge can enhance LLMs' performance. However, for in-domain models like ZhongJing-TCM, the quality of generated analysis text has decreased, and we hypothesize that their fine-tuning process affects the basic LLM capabilities. (3) Traditional metrics for text generation quality like Rouge and BertScore are susceptible to text length and surface semantic ambiguity, while domain-specific metrics such as TCMScore can further supplement and explain their evaluation results. These findings highlight the capabilities and limitations of LLMs in the TCM and aim to provide a more profound assistance to medical research.