Stain-aware Domain Alignment for Imbalance Blood Cell Classification

Blood cell identification is critical for hematological analysis as it aids physicians in diagnosing various blood-related diseases. In real-world scenarios, blood cell image datasets often present the issues of domain shift and data imbalance, posing challenges for accurate blood cell identification. To address these issues, we propose a novel blood cell classification method termed SADA via stain-aware domain alignment. The primary objective of this work is to mine domain-invariant features in the presence of domain shifts and data imbalances. To accomplish this objective, we propose a stain-based augmentation approach and a local alignment constraint to learn domain-invariant features. Furthermore, we propose a domain-invariant supervised contrastive learning strategy to capture discriminative features. We decouple the training process into two stages of domain-invariant feature learning and classification training, alleviating the problem of data imbalance. Experiment results on four public blood cell datasets and a private real dataset collected from the Third Affiliated Hospital of Sun Yat-sen University demonstrate that SADA can achieve a new state-of-the-art baseline, which is superior to the existing cutting-edge methods with a big margin. The source code can be available at the URL (\url{https://github.com/AnoK3111/SADA}).

LoCo: Low-Contrast-Enhanced Contrastive Learning for Semi-Supervised Endoscopic Image Segmentation

The segmentation of endoscopic images plays a vital role in computer-aided diagnosis and treatment. The advancements in deep learning have led to the employment of numerous models for endoscopic tumor segmentation, achieving promising segmentation performance. Despite recent advancements, precise segmentation remains challenging due to limited annotations and the issue of low contrast. To address these issues, we propose a novel semi-supervised segmentation framework termed LoCo via low-contrast-enhanced contrastive learning (LCC). This innovative approach effectively harnesses the vast amounts of unlabeled data available for endoscopic image segmentation, improving both accuracy and robustness in the segmentation process. Specifically, LCC incorporates two advanced strategies to enhance the distinctiveness of low-contrast pixels: inter-class contrast enhancement (ICE) and boundary contrast enhancement (BCE), enabling models to segment low-contrast pixels among malignant tumors, benign tumors, and normal tissues. Additionally, a confidence-based dynamic filter (CDF) is designed for pseudo-label selection, enhancing the utilization of generated pseudo-labels for unlabeled data with a specific focus on minority classes. Extensive experiments conducted on two public datasets, as well as a large proprietary dataset collected over three years, demonstrate that LoCo achieves state-of-the-art results, significantly outperforming previous methods. The source code of LoCo is available at the URL of https://github.com/AnoK3111/LoCo.

SAM-Swin: SAM-Driven Dual-Swin Transformers with Adaptive Lesion Enhancement for Laryngo-Pharyngeal Tumor Detection

Laryngo-pharyngeal cancer (LPC) is a highly lethal malignancy in the head and neck region. Recent advancements in tumor detection, particularly through dual-branch network architectures, have significantly improved diagnostic accuracy by integrating global and local feature extraction. However, challenges remain in accurately localizing lesions and fully capitalizing on the complementary nature of features within these branches. To address these issues, we propose SAM-Swin, an innovative SAM-driven Dual-Swin Transformer for laryngo-pharyngeal tumor detection. This model leverages the robust segmentation capabilities of the Segment Anything Model 2 (SAM2) to achieve precise lesion segmentation. Meanwhile, we present a multi-scale lesion-aware enhancement module (MS-LAEM) designed to adaptively enhance the learning of nuanced complementary features across various scales, improving the quality of feature extraction and representation. Furthermore, we implement a multi-scale class-aware guidance (CAG) loss that delivers multi-scale targeted supervision, thereby enhancing the model's capacity to extract class-specific features. To validate our approach, we compiled three LPC datasets from the First Affiliated Hospital (FAHSYSU), the Sixth Affiliated Hospital (SAHSYSU) of Sun Yat-sen University, and Nanfang Hospital of Southern Medical University (NHSMU). The FAHSYSU dataset is utilized for internal training, while the SAHSYSU and NHSMU datasets serve for external evaluation. Extensive experiments demonstrate that SAM-Swin outperforms state-of-the-art methods, showcasing its potential for advancing LPC detection and improving patient outcomes. The source code of SAM-Swin is available at the URL of \href{https://github.com/VVJia/SAM-Swin}{https://github.com/VVJia/SAM-Swin}.

Mamba-Enhanced Text-Audio-Video Alignment Network for Emotion Recognition in Conversations

Emotion Recognition in Conversations (ERCs) is a vital area within multimodal interaction research, dedicated to accurately identifying and classifying the emotions expressed by speakers throughout a conversation. Traditional ERC approaches predominantly rely on unimodal cues\-such as text, audio, or visual data\-leading to limitations in their effectiveness. These methods encounter two significant challenges: 1) Consistency in multimodal information. Before integrating various modalities, it is crucial to ensure that the data from different sources is aligned and coherent. 2) Contextual information capture. Successfully fusing multimodal features requires a keen understanding of the evolving emotional tone, especially in lengthy dialogues where emotions may shift and develop over time. To address these limitations, we propose a novel Mamba-enhanced Text-Audio-Video alignment network (MaTAV) for the ERC task. MaTAV is with the advantages of aligning unimodal features to ensure consistency across different modalities and handling long input sequences to better capture contextual multimodal information. The extensive experiments on the MELD and IEMOCAP datasets demonstrate that MaTAV significantly outperforms existing state-of-the-art methods on the ERC task with a big margin.

3D-LSPTM: An Automatic Framework with 3D-Large-Scale Pretrained Model for Laryngeal Cancer Detection Using Laryngoscopic Videos

Laryngeal cancer is a malignant disease with a high morality rate in otorhinolaryngology, posing an significant threat to human health. Traditionally larygologists manually visual-inspect laryngeal cancer in laryngoscopic videos, which is quite time-consuming and subjective. In this study, we propose a novel automatic framework via 3D-large-scale pretrained models termed 3D-LSPTM for laryngeal cancer detection. Firstly, we collect 1,109 laryngoscopic videos from the First Affiliated Hospital Sun Yat-sen University with the approval of the Ethics Committee. Then we utilize the 3D-large-scale pretrained models of C3D, TimeSformer, and Video-Swin-Transformer, with the merit of advanced featuring videos, for laryngeal cancer detection with fine-tuning techniques. Extensive experiments show that our proposed 3D-LSPTM can achieve promising performance on the task of laryngeal cancer detection. Particularly, 3D-LSPTM with the backbone of Video-Swin-Transformer can achieve 92.4% accuracy, 95.6% sensitivity, 94.1% precision, and 94.8% F_1.

SAM-FNet: SAM-Guided Fusion Network for Laryngo-Pharyngeal Tumor Detection

Laryngo-pharyngeal cancer (LPC) is a highly fatal malignant disease affecting the head and neck region. Previous studies on endoscopic tumor detection, particularly those leveraging dual-branch network architectures, have shown significant advancements in tumor detection. These studies highlight the potential of dual-branch networks in improving diagnostic accuracy by effectively integrating global and local (lesion) feature extraction. However, they are still limited in their capabilities to accurately locate the lesion region and capture the discriminative feature information between the global and local branches. To address these issues, we propose a novel SAM-guided fusion network (SAM-FNet), a dual-branch network for laryngo-pharyngeal tumor detection. By leveraging the powerful object segmentation capabilities of the Segment Anything Model (SAM), we introduce the SAM into the SAM-FNet to accurately segment the lesion region. Furthermore, we propose a GAN-like feature optimization (GFO) module to capture the discriminative features between the global and local branches, enhancing the fusion feature complementarity. Additionally, we collect two LPC datasets from the First Affiliated Hospital (FAHSYSU) and the Sixth Affiliated Hospital (SAHSYSU) of Sun Yat-sen University. The FAHSYSU dataset is used as the internal dataset for training the model, while the SAHSYSU dataset is used as the external dataset for evaluating the model's performance. Extensive experiments on both datasets of FAHSYSU and SAHSYSU demonstrate that the SAM-FNet can achieve competitive results, outperforming the state-of-the-art counterparts. The source code of SAM-FNet is available at the URL of https://github.com/VVJia/SAM-FNet.

Domain-invariant Representation Learning via Segment Anything Model for Blood Cell Classification

Accurate classification of blood cells is of vital significance in the diagnosis of hematological disorders. However, in real-world scenarios, domain shifts caused by the variability in laboratory procedures and settings, result in a rapid deterioration of the model's generalization performance. To address this issue, we propose a novel framework of domain-invariant representation learning (DoRL) via segment anything model (SAM) for blood cell classification. The DoRL comprises two main components: a LoRA-based SAM (LoRA-SAM) and a cross-domain autoencoder (CAE). The advantage of DoRL is that it can extract domain-invariant representations from various blood cell datasets in an unsupervised manner. Specifically, we first leverage the large-scale foundation model of SAM, fine-tuned with LoRA, to learn general image embeddings and segment blood cells. Additionally, we introduce CAE to learn domain-invariant representations across different-domain datasets while mitigating images' artifacts. To validate the effectiveness of domain-invariant representations, we employ five widely used machine learning classifiers to construct blood cell classification models. Experimental results on two public blood cell datasets and a private real dataset demonstrate that our proposed DoRL achieves a new state-of-the-art cross-domain performance, surpassing existing methods by a significant margin. The source code can be available at the URL (https://github.com/AnoK3111/DoRL).

Towards Cross-Domain Single Blood Cell Image Classification via Large-Scale LoRA-based Segment Anything Model

Accurate classification of blood cells plays a vital role in hematological analysis as it aids physicians in diagnosing various medical conditions. In this study, we present a novel approach for classifying blood cell images known as BC-SAM. BC-SAM leverages the large-scale foundation model of Segment Anything Model (SAM) and incorporates a fine-tuning technique using LoRA, allowing it to extract general image embeddings from blood cell images. To enhance the applicability of BC-SAM across different blood cell image datasets, we introduce an unsupervised cross-domain autoencoder that focuses on learning intrinsic features while suppressing artifacts in the images. To assess the performance of BC-SAM, we employ four widely used machine learning classifiers (Random Forest, Support Vector Machine, Artificial Neural Network, and XGBoost) to construct blood cell classification models and compare them against existing state-of-the-art methods. Experimental results conducted on two publicly available blood cell datasets (Matek-19 and Acevedo-20) demonstrate that our proposed BC-SAM achieves a new state-of-the-art result, surpassing the baseline methods with a significant improvement. The source code of this paper is available at https://github.com/AnoK3111/BC-SAM.

Core Knowledge Learning Framework for Graph Adaptation and Scalability Learning

Graph classification is a pivotal challenge in machine learning, especially within the realm of graph-based data, given its importance in numerous real-world applications such as social network analysis, recommendation systems, and bioinformatics. Despite its significance, graph classification faces several hurdles, including adapting to diverse prediction tasks, training across multiple target domains, and handling small-sample prediction scenarios. Current methods often tackle these challenges individually, leading to fragmented solutions that lack a holistic approach to the overarching problem. In this paper, we propose an algorithm aimed at addressing the aforementioned challenges. By incorporating insights from various types of tasks, our method aims to enhance adaptability, scalability, and generalizability in graph classification. Motivated by the recognition that the underlying subgraph plays a crucial role in GNN prediction, while the remainder is task-irrelevant, we introduce the Core Knowledge Learning (\method{}) framework for graph adaptation and scalability learning. \method{} comprises several key modules, including the core subgraph knowledge submodule, graph domain adaptation module, and few-shot learning module for downstream tasks. Each module is tailored to tackle specific challenges in graph classification, such as domain shift, label inconsistencies, and data scarcity. By learning the core subgraph of the entire graph, we focus on the most pertinent features for task relevance. Consequently, our method offers benefits such as improved model performance, increased domain adaptability, and enhanced robustness to domain variations. Experimental results demonstrate significant performance enhancements achieved by our method compared to state-of-the-art approaches.

Video-based Smoky Vehicle Detection with A Coarse-to-Fine Framework

Automatic smoky vehicle detection in videos is a superior solution to the traditional expensive remote sensing one with ultraviolet-infrared light devices for environmental protection agencies. However, it is challenging to distinguish vehicle smoke from shadow and wet regions coming from rear vehicle or clutter roads, and could be worse due to limited annotated data. In this paper, we first introduce a real-world large-scale smoky vehicle dataset with 75,000 annotated smoky vehicle images, facilitating the effective training of advanced deep learning models. To enable fair algorithm comparison, we also build a smoky vehicle video dataset including 163 long videos with segment-level annotations. Moreover, we present a new Coarse-to-fine Deep Smoky vehicle detection (CoDeS) framework for efficient smoky vehicle detection. The CoDeS first leverages a light-weight YOLO detector for fast smoke detection with high recall rate, and then applies a smoke-vehicle matching strategy to eliminate non-vehicle smoke, and finally uses a elaborately-designed 3D model to further refine the results in spatial temporal space. Extensive experiments in four metrics demonstrate that our framework is significantly superior to those hand-crafted feature based methods and recent advanced methods. The code and dataset will be released at https://github.com/pengxj/smokyvehicle.