Accelerating Discovery in Natural Science Laboratories with AI and Robotics: Perspectives and Challenges from the 2024 IEEE ICRA Workshop, Yokohama, Japan

Science laboratory automation enables accelerated discovery in life sciences and materials. However, it requires interdisciplinary collaboration to address challenges such as robust and flexible autonomy, reproducibility, throughput, standardization, the role of human scientists, and ethics. This article highlights these issues, reflecting perspectives from leading experts in laboratory automation across different disciplines of the natural sciences.

ORGANA: A Robotic Assistant for Automated Chemistry Experimentation and Characterization

Chemistry experimentation is often resource- and labor-intensive. Despite the many benefits incurred by the integration of advanced and special-purpose lab equipment, many aspects of experimentation are still manually conducted by chemists, for example, polishing an electrode in electrochemistry experiments. Traditional lab automation infrastructure faces challenges when it comes to flexibly adapting to new chemistry experiments. To address this issue, we propose a human-friendly and flexible robotic system, ORGANA, that automates a diverse set of chemistry experiments. It is capable of interacting with chemists in the lab through natural language, using Large Language Models (LLMs). ORGANA keeps scientists informed by providing timely reports that incorporate statistical analyses. Additionally, it actively engages with users when necessary for disambiguation or troubleshooting. ORGANA can reason over user input to derive experiment goals, and plan long sequences of both high-level tasks and low-level robot actions while using feedback from the visual perception of the environment. It also supports scheduling and parallel execution for experiments that require resource allocation and coordination between multiple robots and experiment stations. We show that ORGANA successfully conducts a diverse set of chemistry experiments, including solubility assessment, pH measurement, recrystallization, and electrochemistry experiments. For the latter, we show that ORGANA robustly executes a long-horizon plan, comprising 19 steps executed in parallel, to characterize the electrochemical properties of quinone derivatives, a class of molecules used in rechargeable flow batteries. Our user study indicates that ORGANA significantly improves many aspects of user experience while reducing their physical workload. More details about ORGANA can be found at https://ac-rad.github.io/organa/.

RePLan: Robotic Replanning with Perception and Language Models

Advancements in large language models (LLMs) have demonstrated their potential in facilitating high-level reasoning, logical reasoning and robotics planning. Recently, LLMs have also been able to generate reward functions for low-level robot actions, effectively bridging the interface between high-level planning and low-level robot control. However, the challenge remains that even with syntactically correct plans, robots can still fail to achieve their intended goals. This failure can be attributed to imperfect plans proposed by LLMs or to unforeseeable environmental circumstances that hinder the execution of planned subtasks due to erroneous assumptions about the state of objects. One way to prevent these challenges is to rely on human-provided step-by-step instructions, limiting the autonomy of robotic systems. Vision Language Models (VLMs) have shown remarkable success in tasks such as visual question answering and image captioning. Leveraging the capabilities of VLMs, we present a novel framework called Robotic Replanning with Perception and Language Models (RePLan) that enables real-time replanning capabilities for long-horizon tasks. This framework utilizes the physical grounding provided by a VLM's understanding of the world's state to adapt robot actions when the initial plan fails to achieve the desired goal. We test our approach within four environments containing seven long-horizion tasks. We find that RePLan enables a robot to successfully adapt to unforeseen obstacles while accomplishing open-ended, long-horizon goals, where baseline models cannot. Find more information at https://replan-lm.github.io/replan.github.io/

Errors are Useful Prompts: Instruction Guided Task Programming with Verifier-Assisted Iterative Prompting

Generating low-level robot task plans from high-level natural language instructions remains a challenging problem. Although large language models have shown promising results in generating plans, the accuracy of the output remains unverified. Furthermore, the lack of domain-specific language data poses a limitation on the applicability of these models. In this paper, we propose CLAIRIFY, a novel approach that combines automatic iterative prompting with program verification to ensure programs written in data-scarce domain-specific language are syntactically valid and incorporate environment constraints. Our approach provides effective guidance to the language model on generating structured-like task plans by incorporating any errors as feedback, while the verifier ensures the syntactic accuracy of the generated plans. We demonstrate the effectiveness of CLAIRIFY in planning chemistry experiments by achieving state-of-the-art results. We also show that the generated plans can be executed on a real robot by integrating them with a task and motion planner.

Simultaneous Action Recognition and Human Whole-Body Motion and Dynamics Prediction from Wearable Sensors

This paper presents a novel approach to solve simultaneously the problems of human activity recognition and whole-body motion and dynamics prediction for real-time applications. Starting from the dynamics of human motion and motor system theory, the notion of mixture of experts from deep learning has been extended to address this problem. In the proposed approach, experts are modelled as a sequence-to-sequence recurrent neural networks (RNN) architecture. Experiments show the results of 66-DoF real-world human motion prediction and action recognition during different tasks like walking and rotating. The code associated with this paper is available at: \url{github.com/ami-iit/paper_darvish_2022_humanoids_action-kindyn-predicition}

Teleoperation of Humanoid Robots: A Survey

Teleoperation of humanoid robots enables the integration of the cognitive skills and domain expertise of humans with the physical capabilities of humanoid robots. The operational versatility of humanoid robots makes them the ideal platform for a wide range of applications when teleoperating in a remote environment. However, the complexity of humanoid robots imposes challenges for teleoperation, particularly in unstructured dynamic environments with limited communication. Many advancements have been achieved in the last decades in this area, but a comprehensive overview is still missing. This survey paper gives an extensive overview of humanoid robot teleoperation, presenting the general architecture of a teleoperation system and analyzing the different components. We also discuss different aspects of the topic, including technological and methodological advances, as well as potential applications. A web-based version of the paper can be found at https://humanoid-teleoperation.github.io/.

An Adaptive Robotics Framework for Chemistry Lab Automation

In the process of materials discovery, chemists currently need to perform many laborious, time-consuming, and often dangerous lab experiments. To accelerate this process, we propose a framework for robots to assist chemists by performing lab experiments autonomously. The solution allows a general-purpose robot to perform diverse chemistry experiments and efficiently make use of available lab tools. Our system can load high-level descriptions of chemistry experiments, perceive a dynamic workspace, and autonomously plan the required actions and motions to perform the given chemistry experiments with common tools found in the existing lab environment. Our architecture uses a modified PDDLStream solver for integrated task and constrained motion planning, which generates plans and motions that are guaranteed to be safe by preventing collisions and spillage. We present a modular framework that can scale to many different experiments, actions, and lab tools. In this work, we demonstrate the utility of our framework on three pouring skills and two foundational chemical experiments for materials synthesis: solubility and recrystallization. More experiments and updated evaluations can be found at https://ac-rad.github.io/arc-icra2023.

iCub3 Avatar System

We present an avatar system that enables a human operator to visit a remote location via iCub3, a new humanoid robot developed at the Italian Institute of Technology (IIT) paving the way for the next generation of the iCub platforms. On the one hand, we present the humanoid iCub3 that plays the role of the robotic avatar. Particular attention is paid to the differences between iCub3 and the classical iCub humanoid robot. On the other hand, we present the set of technologies of the avatar system at the operator side. They are mainly composed of iFeel, namely, IIT lightweight non-invasive wearable devices for motion tracking and haptic feedback, and of non-IIT technologies designed for virtual reality ecosystems. Finally, we show the effectiveness of the avatar system by describing a demonstration involving a realtime teleoperation of the iCub3. The robot is located in Venice, Biennale di Venezia, while the human operator is at more than 290km distance and located in Genoa, IIT. Using a standard fiber optic internet connection, the avatar system transports the operator locomotion, manipulation, voice, and face expressions to the iCub3 with visual, auditory, haptic and touch feedback.

A Task Allocation Approach for Human-Robot Collaboration in Product Defects Inspection Scenarios

The presence and coexistence of human operators and collaborative robots in shop-floor environments raises the need for assigning tasks to either operators or robots, or both. Depending on task characteristics, operator capabilities and the involved robot functionalities, it is of the utmost importance to design strategies allowing for the concurrent and/or sequential allocation of tasks related to object manipulation and assembly. In this paper, we extend the \textsc{FlexHRC} framework presented in \cite{darvish2018flexible} to allow a human operator to interact with multiple, heterogeneous robots at the same time in order to jointly carry out a given task. The extended \textsc{FlexHRC} framework leverages a concurrent and sequential task representation framework to allocate tasks to either operators or robots as part of a dynamic collaboration process. In particular, we focus on a use case related to the inspection of product defects, which involves a human operator, a dual-arm Baxter manipulator from Rethink Robotics and a Kuka youBot mobile manipulator.

A Hierarchical Architecture for Human-Robot Cooperation Processes

In this paper we propose FlexHRC+, a hierarchical human-robot cooperation architecture designed to provide collaborative robots with an extended degree of autonomy when supporting human operators in high-variability shop-floor tasks. The architecture encompasses three levels, namely for perception, representation, and action. Building up on previous work, here we focus on (i) an in-the-loop decision making process for the operations of collaborative robots coping with the variability of actions carried out by human operators, and (ii) the representation level, integrating a hierarchical AND/OR graph whose online behaviour is formally specified using First Order Logic. The architecture is accompanied by experiments including collaborative furniture assembly and object positioning tasks.