How does the primate brain combine generative and discriminative computations in vision?

Vision is widely understood as an inference problem. However, two contrasting conceptions of the inference process have each been influential in research on biological vision as well as the engineering of machine vision. The first emphasizes bottom-up signal flow, describing vision as a largely feedforward, discriminative inference process that filters and transforms the visual information to remove irrelevant variation and represent behaviorally relevant information in a format suitable for downstream functions of cognition and behavioral control. In this conception, vision is driven by the sensory data, and perception is direct because the processing proceeds from the data to the latent variables of interest. The notion of "inference" in this conception is that of the engineering literature on neural networks, where feedforward convolutional neural networks processing images are said to perform inference. The alternative conception is that of vision as an inference process in Helmholtz's sense, where the sensory evidence is evaluated in the context of a generative model of the causal processes giving rise to it. In this conception, vision inverts a generative model through an interrogation of the evidence in a process often thought to involve top-down predictions of sensory data to evaluate the likelihood of alternative hypotheses. The authors include scientists rooted in roughly equal numbers in each of the conceptions and motivated to overcome what might be a false dichotomy between them and engage the other perspective in the realm of theory and experiment. The primate brain employs an unknown algorithm that may combine the advantages of both conceptions. We explain and clarify the terminology, review the key empirical evidence, and propose an empirical research program that transcends the dichotomy and sets the stage for revealing the mysterious hybrid algorithm of primate vision.

Probing Biological and Artificial Neural Networks with Task-dependent Neural Manifolds

Recently, growth in our understanding of the computations performed in both biological and artificial neural networks has largely been driven by either low-level mechanistic studies or global normative approaches. However, concrete methodologies for bridging the gap between these levels of abstraction remain elusive. In this work, we investigate the internal mechanisms of neural networks through the lens of neural population geometry, aiming to provide understanding at an intermediate level of abstraction, as a way to bridge that gap. Utilizing manifold capacity theory (MCT) from statistical physics and manifold alignment analysis (MAA) from high-dimensional statistics, we probe the underlying organization of task-dependent manifolds in deep neural networks and macaque neural recordings. Specifically, we quantitatively characterize how different learning objectives lead to differences in the organizational strategies of these models and demonstrate how these geometric analyses are connected to the decodability of task-relevant information. These analyses present a strong direction for bridging mechanistic and normative theories in neural networks through neural population geometry, potentially opening up many future research avenues in both machine learning and neuroscience.

Robustified ANNs Reveal Wormholes Between Human Category Percepts

The visual object category reports of artificial neural networks (ANNs) are notoriously sensitive to tiny, adversarial image perturbations. Because human category reports (aka human percepts) are thought to be insensitive to those same small-norm perturbations -- and locally stable in general -- this argues that ANNs are incomplete scientific models of human visual perception. Consistent with this, we show that when small-norm image perturbations are generated by standard ANN models, human object category percepts are indeed highly stable. However, in this very same "human-presumed-stable" regime, we find that robustified ANNs reliably discover low-norm image perturbations that strongly disrupt human percepts. These previously undetectable human perceptual disruptions are massive in amplitude, approaching the same level of sensitivity seen in robustified ANNs. Further, we show that robustified ANNs support precise perceptual state interventions: they guide the construction of low-norm image perturbations that strongly alter human category percepts toward specific prescribed percepts. These observations suggest that for arbitrary starting points in image space, there exists a set of nearby "wormholes", each leading the subject from their current category perceptual state into a semantically very different state. Moreover, contemporary ANN models of biological visual processing are now accurate enough to consistently guide us to those portals.

Adversarially trained neural representations may already be as robust as corresponding biological neural representations

Visual systems of primates are the gold standard of robust perception. There is thus a general belief that mimicking the neural representations that underlie those systems will yield artificial visual systems that are adversarially robust. In this work, we develop a method for performing adversarial visual attacks directly on primate brain activity. We then leverage this method to demonstrate that the above-mentioned belief might not be well founded. Specifically, we report that the biological neurons that make up visual systems of primates exhibit susceptibility to adversarial perturbations that is comparable in magnitude to existing (robustly trained) artificial neural networks.

Neural Population Geometry Reveals the Role of Stochasticity in Robust Perception

Adversarial examples are often cited by neuroscientists and machine learning researchers as an example of how computational models diverge from biological sensory systems. Recent work has proposed adding biologically-inspired components to visual neural networks as a way to improve their adversarial robustness. One surprisingly effective component for reducing adversarial vulnerability is response stochasticity, like that exhibited by biological neurons. Here, using recently developed geometrical techniques from computational neuroscience, we investigate how adversarial perturbations influence the internal representations of standard, adversarially trained, and biologically-inspired stochastic networks. We find distinct geometric signatures for each type of network, revealing different mechanisms for achieving robust representations. Next, we generalize these results to the auditory domain, showing that neural stochasticity also makes auditory models more robust to adversarial perturbations. Geometric analysis of the stochastic networks reveals overlap between representations of clean and adversarially perturbed stimuli, and quantitatively demonstrates that competing geometric effects of stochasticity mediate a tradeoff between adversarial and clean performance. Our results shed light on the strategies of robust perception utilized by adversarially trained and stochastic networks, and help explain how stochasticity may be beneficial to machine and biological computation.

Combining Different V1 Brain Model Variants to Improve Robustness to Image Corruptions in CNNs

While some convolutional neural networks (CNNs) have surpassed human visual abilities in object classification, they often struggle to recognize objects in images corrupted with different types of common noise patterns, highlighting a major limitation of this family of models. Recently, it has been shown that simulating a primary visual cortex (V1) at the front of CNNs leads to small improvements in robustness to these image perturbations. In this study, we start with the observation that different variants of the V1 model show gains for specific corruption types. We then build a new model using an ensembling technique, which combines multiple individual models with different V1 front-end variants. The model ensemble leverages the strengths of each individual model, leading to significant improvements in robustness across all corruption categories and outperforming the base model by 38% on average. Finally, we show that using distillation, it is possible to partially compress the knowledge in the ensemble model into a single model with a V1 front-end. While the ensembling and distillation techniques used here are hardly biologically-plausible, the results presented here demonstrate that by combining the specific strengths of different neuronal circuits in V1 it is possible to improve the robustness of CNNs for a wide range of perturbations.

ThreeDWorld: A Platform for Interactive Multi-Modal Physical Simulation

We introduce ThreeDWorld (TDW), a platform for interactive multi-modal physical simulation. With TDW, users can simulate high-fidelity sensory data and physical interactions between mobile agents and objects in a wide variety of rich 3D environments. TDW has several unique properties: 1) realtime near photo-realistic image rendering quality; 2) a library of objects and environments with materials for high-quality rendering, and routines enabling user customization of the asset library; 3) generative procedures for efficiently building classes of new environments 4) high-fidelity audio rendering; 5) believable and realistic physical interactions for a wide variety of material types, including cloths, liquid, and deformable objects; 6) a range of "avatar" types that serve as embodiments of AI agents, with the option for user avatar customization; and 7) support for human interactions with VR devices. TDW also provides a rich API enabling multiple agents to interact within a simulation and return a range of sensor and physics data representing the state of the world. We present initial experiments enabled by the platform around emerging research directions in computer vision, machine learning, and cognitive science, including multi-modal physical scene understanding, multi-agent interactions, models that "learn like a child", and attention studies in humans and neural networks. The simulation platform will be made publicly available.

Brain-Like Object Recognition with High-Performing Shallow Recurrent ANNs

Deep convolutional artificial neural networks (ANNs) are the leading class of candidate models of the mechanisms of visual processing in the primate ventral stream. While initially inspired by brain anatomy, over the past years, these ANNs have evolved from a simple eight-layer architecture in AlexNet to extremely deep and branching architectures, demonstrating increasingly better object categorization performance, yet bringing into question how brain-like they still are. In particular, typical deep models from the machine learning community are often hard to map onto the brain's anatomy due to their vast number of layers and missing biologically-important connections, such as recurrence. Here we demonstrate that better anatomical alignment to the brain and high performance on machine learning as well as neuroscience measures do not have to be in contradiction. We developed CORnet-S, a shallow ANN with four anatomically mapped areas and recurrent connectivity, guided by Brain-Score, a new large-scale composite of neural and behavioral benchmarks for quantifying the functional fidelity of models of the primate ventral visual stream. Despite being significantly shallower than most models, CORnet-S is the top model on Brain-Score and outperforms similarly compact models on ImageNet. Moreover, our extensive analyses of CORnet-S circuitry variants reveal that recurrence is the main predictive factor of both Brain-Score and ImageNet top-1 performance. Finally, we report that the temporal evolution of the CORnet-S "IT" neural population resembles the actual monkey IT population dynamics. Taken together, these results establish CORnet-S, a compact, recurrent ANN, as the current best model of the primate ventral visual stream.

Task-Driven Convolutional Recurrent Models of the Visual System

Feed-forward convolutional neural networks (CNNs) are currently state-of-the-art for object classification tasks such as ImageNet. Further, they are quantitatively accurate models of temporally-averaged responses of neurons in the primate brain's visual system. However, biological visual systems have two ubiquitous architectural features not shared with typical CNNs: local recurrence within cortical areas, and long-range feedback from downstream areas to upstream areas. Here we explored the role of recurrence in improving classification performance. We found that standard forms of recurrence (vanilla RNNs and LSTMs) do not perform well within deep CNNs on the ImageNet task. In contrast, novel cells that incorporated two structural features, bypassing and gating, were able to boost task accuracy substantially. We extended these design principles in an automated search over thousands of model architectures, which identified novel local recurrent cells and long-range feedback connections useful for object recognition. Moreover, these task-optimized ConvRNNs matched the dynamics of neural activity in the primate visual system better than feedforward networks, suggesting a role for the brain's recurrent connections in performing difficult visual behaviors.

Deep Neural Networks Rival the Representation of Primate IT Cortex for Core Visual Object Recognition

The primate visual system achieves remarkable visual object recognition performance even in brief presentations and under changes to object exemplar, geometric transformations, and background variation (a.k.a. core visual object recognition). This remarkable performance is mediated by the representation formed in inferior temporal (IT) cortex. In parallel, recent advances in machine learning have led to ever higher performing models of object recognition using artificial deep neural networks (DNNs). It remains unclear, however, whether the representational performance of DNNs rivals that of the brain. To accurately produce such a comparison, a major difficulty has been a unifying metric that accounts for experimental limitations such as the amount of noise, the number of neural recording sites, and the number trials, and computational limitations such as the complexity of the decoding classifier and the number of classifier training examples. In this work we perform a direct comparison that corrects for these experimental limitations and computational considerations. As part of our methodology, we propose an extension of "kernel analysis" that measures the generalization accuracy as a function of representational complexity. Our evaluations show that, unlike previous bio-inspired models, the latest DNNs rival the representational performance of IT cortex on this visual object recognition task. Furthermore, we show that models that perform well on measures of representational performance also perform well on measures of representational similarity to IT and on measures of predicting individual IT multi-unit responses. Whether these DNNs rely on computational mechanisms similar to the primate visual system is yet to be determined, but, unlike all previous bio-inspired models, that possibility cannot be ruled out merely on representational performance grounds.