BATseg: Boundary-aware Multiclass Spinal Cord Tumor Segmentation on 3D MRI Scans

Spinal cord tumors significantly contribute to neurological morbidity and mortality. Precise morphometric quantification, encompassing the size, location, and type of such tumors, holds promise for optimizing treatment planning strategies. Although recent methods have demonstrated excellent performance in medical image segmentation, they primarily focus on discerning shapes with relatively large morphology such as brain tumors, ignoring the challenging problem of identifying spinal cord tumors which tend to have tiny sizes, diverse locations, and shapes. To tackle this hard problem of multiclass spinal cord tumor segmentation, we propose a new method, called BATseg, to learn a tumor surface distance field by applying our new multiclass boundary-aware loss function. To verify the effectiveness of our approach, we also introduce the first and large-scale spinal cord tumor dataset. It comprises gadolinium-enhanced T1-weighted 3D MRI scans from 653 patients and contains the four most common spinal cord tumor types: astrocytomas, ependymomas, hemangioblastomas, and spinal meningiomas. Extensive experiments on our dataset and another public kidney tumor segmentation dataset show that our proposed method achieves superior performance for multiclass tumor segmentation.

DD-VNB: A Depth-based Dual-Loop Framework for Real-time Visually Navigated Bronchoscopy

Real-time 6 DOF localization of bronchoscopes is crucial for enhancing intervention quality. However, current vision-based technologies struggle to balance between generalization to unseen data and computational speed. In this study, we propose a Depth-based Dual-Loop framework for real-time Visually Navigated Bronchoscopy (DD-VNB) that can generalize across patient cases without the need of re-training. The DD-VNB framework integrates two key modules: depth estimation and dual-loop localization. To address the domain gap among patients, we propose a knowledge-embedded depth estimation network that maps endoscope frames to depth, ensuring generalization by eliminating patient-specific textures. The network embeds view synthesis knowledge into a cycle adversarial architecture for scale-constrained monocular depth estimation. For real-time performance, our localization module embeds a fast ego-motion estimation network into the loop of depth registration. The ego-motion inference network estimates the pose change of the bronchoscope in high frequency while depth registration against the pre-operative 3D model provides absolute pose periodically. Specifically, the relative pose changes are fed into the registration process as the initial guess to boost its accuracy and speed. Experiments on phantom and in-vivo data from patients demonstrate the effectiveness of our framework: 1) monocular depth estimation outperforms SOTA, 2) localization achieves an accuracy of Absolute Tracking Error (ATE) of 4.7 $\pm$ 3.17 mm in phantom and 6.49 $\pm$ 3.88 mm in patient data, 3) with a frame-rate approaching video capture speed, 4) without the necessity of case-wise network retraining. The framework's superior speed and accuracy demonstrate its promising clinical potential for real-time bronchoscopic navigation.

LMSanitator: Defending Prompt-Tuning Against Task-Agnostic Backdoors

Prompt-tuning has emerged as an attractive paradigm for deploying large-scale language models due to its strong downstream task performance and efficient multitask serving ability. Despite its wide adoption, we empirically show that prompt-tuning is vulnerable to downstream task-agnostic backdoors, which reside in the pretrained models and can affect arbitrary downstream tasks. The state-of-the-art backdoor detection approaches cannot defend against task-agnostic backdoors since they hardly converge in reversing the backdoor triggers. To address this issue, we propose LMSanitator, a novel approach for detecting and removing task-agnostic backdoors on Transformer models. Instead of directly inversing the triggers, LMSanitator aims to inverse the predefined attack vectors (pretrained models' output when the input is embedded with triggers) of the task-agnostic backdoors, which achieves much better convergence performance and backdoor detection accuracy. LMSanitator further leverages prompt-tuning's property of freezing the pretrained model to perform accurate and fast output monitoring and input purging during the inference phase. Extensive experiments on multiple language models and NLP tasks illustrate the effectiveness of LMSanitator. For instance, LMSanitator achieves 92.8% backdoor detection accuracy on 960 models and decreases the attack success rate to less than 1% in most scenarios.

GrowSP: Unsupervised Semantic Segmentation of 3D Point Clouds

We study the problem of 3D semantic segmentation from raw point clouds. Unlike existing methods which primarily rely on a large amount of human annotations for training neural networks, we propose the first purely unsupervised method, called GrowSP, to successfully identify complex semantic classes for every point in 3D scenes, without needing any type of human labels or pretrained models. The key to our approach is to discover 3D semantic elements via progressive growing of superpoints. Our method consists of three major components, 1) the feature extractor to learn per-point features from input point clouds, 2) the superpoint constructor to progressively grow the sizes of superpoints, and 3) the semantic primitive clustering module to group superpoints into semantic elements for the final semantic segmentation. We extensively evaluate our method on multiple datasets, demonstrating superior performance over all unsupervised baselines and approaching the classic fully-supervised PointNet. We hope our work could inspire more advanced methods for unsupervised 3D semantic learning.

Reconstructing A Large Scale 3D Face Dataset for Deep 3D Face Identification

Deep learning methods have brought many breakthroughs to computer vision, especially in 2D face recognition. However, the bottleneck of deep learning based 3D face recognition is that it is difficult to collect millions of 3D faces, whether for industry or academia. In view of this situation, there are many methods to generate more 3D faces from existing 3D faces through 3D face data augmentation, which are used to train deep 3D face recognition models. However, to the best of our knowledge, there is no method to generate 3D faces from 2D face images for training deep 3D face recognition models. This letter focuses on the role of reconstructed 3D facial surfaces in 3D face identification and proposes a framework of 2D-aided deep 3D face identification. In particular, we propose to reconstruct millions of 3D face scans from a large scale 2D face database (i.e.VGGFace2), using a deep learning based 3D face reconstruction method (i.e.ExpNet). Then, we adopt a two-phase training approach: In the first phase, we use millions of face images to pre-train the deep convolutional neural network (DCNN), and in the second phase, we use normal component images (NCI) of reconstructed 3D face scans to train the DCNN. Extensive experimental results illustrate that the proposed approach can greatly improve the rank-1 score of 3D face identification on the FRGC v2.0, the Bosphorus, and the BU-3DFE 3D face databases, compared to the model trained by 2D face images. Finally, our proposed approach achieves state-of-the-art rank-1 scores on the FRGC v2.0 (97.6%), Bosphorus (98.4%), and BU-3DFE (98.8%) databases. The experimental results show that the reconstructed 3D facial surfaces are useful and our 2D-aided deep 3D face identification framework is meaningful, facing the scarcity of 3D faces.