VGAT: A Cancer Survival Analysis Framework Transitioning from Generative Visual Question Answering to Genomic Reconstruction

Multimodal learning combining pathology images and genomic sequences enhances cancer survival analysis but faces clinical implementation barriers due to limited access to genomic sequencing in under-resourced regions. To enable survival prediction using only whole-slide images (WSI), we propose the Visual-Genomic Answering-Guided Transformer (VGAT), a framework integrating Visual Question Answering (VQA) techniques for genomic modality reconstruction. By adapting VQA's text feature extraction approach, we derive stable genomic representations that circumvent dimensionality challenges in raw genomic data. Simultaneously, a cluster-based visual prompt module selectively enhances discriminative WSI patches, addressing noise from unfiltered image regions. Evaluated across five TCGA datasets, VGAT outperforms existing WSI-only methods, demonstrating the viability of genomic-informed inference without sequencing. This approach bridges multimodal research and clinical feasibility in resource-constrained settings. The code link is https://github.com/CZZZZZZZZZZZZZZZZZ/VGAT.

Music-Driven Legged Robots: Synchronized Walking to Rhythmic Beats

We address the challenge of effectively controlling the locomotion of legged robots by incorporating precise frequency and phase characteristics, which is often ignored in locomotion policies that do not account for the periodic nature of walking. We propose a hierarchical architecture that integrates a low-level phase tracker, oscillators, and a high-level phase modulator. This controller allows quadruped robots to walk in a natural manner that is synchronized with external musical rhythms. Our method generates diverse gaits across different frequencies and achieves real-time synchronization with music in the physical world. This research establishes a foundational framework for enabling real-time execution of accurate rhythmic motions in legged robots. Video is available at website: https://music-walker.github.io/.

Continuous Control of Diverse Skills in Quadruped Robots Without Complete Expert Datasets

Learning diverse skills for quadruped robots presents significant challenges, such as mastering complex transitions between different skills and handling tasks of varying difficulty. Existing imitation learning methods, while successful, rely on expensive datasets to reproduce expert behaviors. Inspired by introspective learning, we propose Progressive Adversarial Self-Imitation Skill Transition (PASIST), a novel method that eliminates the need for complete expert datasets. PASIST autonomously explores and selects high-quality trajectories based on predefined target poses instead of demonstrations, leveraging the Generative Adversarial Self-Imitation Learning (GASIL) framework. To further enhance learning, We develop a skill selection module to mitigate mode collapse by balancing the weights of skills with varying levels of difficulty. Through these methods, PASIST is able to reproduce skills corresponding to the target pose while achieving smooth and natural transitions between them. Evaluations on both simulation platforms and the Solo 8 robot confirm the effectiveness of PASIST, offering an efficient alternative to expert-driven learning.

2DGS-Avatar: Animatable High-fidelity Clothed Avatar via 2D Gaussian Splatting

Real-time rendering of high-fidelity and animatable avatars from monocular videos remains a challenging problem in computer vision and graphics. Over the past few years, the Neural Radiance Field (NeRF) has made significant progress in rendering quality but behaves poorly in run-time performance due to the low efficiency of volumetric rendering. Recently, methods based on 3D Gaussian Splatting (3DGS) have shown great potential in fast training and real-time rendering. However, they still suffer from artifacts caused by inaccurate geometry. To address these problems, we propose 2DGS-Avatar, a novel approach based on 2D Gaussian Splatting (2DGS) for modeling animatable clothed avatars with high-fidelity and fast training performance. Given monocular RGB videos as input, our method generates an avatar that can be driven by poses and rendered in real-time. Compared to 3DGS-based methods, our 2DGS-Avatar retains the advantages of fast training and rendering while also capturing detailed, dynamic, and photo-realistic appearances. We conduct abundant experiments on popular datasets such as AvatarRex and THuman4.0, demonstrating impressive performance in both qualitative and quantitative metrics.

Towards Unified Molecule-Enhanced Pathology Image Representation Learning via Integrating Spatial Transcriptomics

Recent advancements in multimodal pre-training models have significantly advanced computational pathology. However, current approaches predominantly rely on visual-language models, which may impose limitations from a molecular perspective and lead to performance bottlenecks. Here, we introduce a Unified Molecule-enhanced Pathology Image REpresentationn Learning framework (UMPIRE). UMPIRE aims to leverage complementary information from gene expression profiles to guide the multimodal pre-training, enhancing the molecular awareness of pathology image representation learning. We demonstrate that this molecular perspective provides a robust, task-agnostic training signal for learning pathology image embeddings. Due to the scarcity of paired data, approximately 4 million entries of spatial transcriptomics gene expression were collected to train the gene encoder. By leveraging powerful pre-trained encoders, UMPIRE aligns the encoders across over 697K pathology image-gene expression pairs. The performance of UMPIRE is demonstrated across various molecular-related downstream tasks, including gene expression prediction, spot classification, and mutation state prediction in whole slide images. Our findings highlight the effectiveness of multimodal data integration and open new avenues for exploring computational pathology enhanced by molecular perspectives. The code and pre-trained weights are available at https://github.com/Hanminghao/UMPIRE.

Toward Robust Incomplete Multimodal Sentiment Analysis via Hierarchical Representation Learning

Multimodal Sentiment Analysis (MSA) is an important research area that aims to understand and recognize human sentiment through multiple modalities. The complementary information provided by multimodal fusion promotes better sentiment analysis compared to utilizing only a single modality. Nevertheless, in real-world applications, many unavoidable factors may lead to situations of uncertain modality missing, thus hindering the effectiveness of multimodal modeling and degrading the model's performance. To this end, we propose a Hierarchical Representation Learning Framework (HRLF) for the MSA task under uncertain missing modalities. Specifically, we propose a fine-grained representation factorization module that sufficiently extracts valuable sentiment information by factorizing modality into sentiment-relevant and modality-specific representations through crossmodal translation and sentiment semantic reconstruction. Moreover, a hierarchical mutual information maximization mechanism is introduced to incrementally maximize the mutual information between multi-scale representations to align and reconstruct the high-level semantics in the representations. Ultimately, we propose a hierarchical adversarial learning mechanism that further aligns and adapts the latent distribution of sentiment-relevant representations to produce robust joint multimodal representations. Comprehensive experiments on three datasets demonstrate that HRLF significantly improves MSA performance under uncertain modality missing cases.

Role Play: Learning Adaptive Role-Specific Strategies in Multi-Agent Interactions

Zero-shot coordination problem in multi-agent reinforcement learning (MARL), which requires agents to adapt to unseen agents, has attracted increasing attention. Traditional approaches often rely on the Self-Play (SP) framework to generate a diverse set of policies in a policy pool, which serves to improve the generalization capability of the final agent. However, these frameworks may struggle to capture the full spectrum of potential strategies, especially in real-world scenarios that demand agents balance cooperation with competition. In such settings, agents need strategies that can adapt to varying and often conflicting goals. Drawing inspiration from Social Value Orientation (SVO)-where individuals maintain stable value orientations during interactions with others-we propose a novel framework called \emph{Role Play} (RP). RP employs role embeddings to transform the challenge of policy diversity into a more manageable diversity of roles. It trains a common policy with role embedding observations and employs a role predictor to estimate the joint role embeddings of other agents, helping the learning agent adapt to its assigned role. We theoretically prove that an approximate optimal policy can be achieved by optimizing the expected cumulative reward relative to an approximate role-based policy. Experimental results in both cooperative (Overcooked) and mixed-motive games (Harvest, CleanUp) reveal that RP consistently outperforms strong baselines when interacting with unseen agents, highlighting its robustness and adaptability in complex environments.

MedAide: Towards an Omni Medical Aide via Specialized LLM-based Multi-Agent Collaboration

Large Language Model (LLM)-driven interactive systems currently show potential promise in healthcare domains. Despite their remarkable capabilities, LLMs typically lack personalized recommendations and diagnosis analysis in sophisticated medical applications, causing hallucinations and performance bottlenecks. To address these challenges, this paper proposes MedAide, an LLM-based omni medical multi-agent collaboration framework for specialized healthcare services. Specifically, MedAide first performs query rewriting through retrieval-augmented generation to accomplish accurate medical intent understanding. Immediately, we devise a contextual encoder to obtain intent prototype embeddings, which are used to recognize fine-grained intents by similarity matching. According to the intent relevance, the activated agents collaborate effectively to provide integrated decision analysis. Extensive experiments are conducted on four medical benchmarks with composite intents. Experimental results from automated metrics and expert doctor evaluations show that MedAide outperforms current LLMs and improves their medical proficiency and strategic reasoning.

A Robust Quadruped Robot with Twisting Waist for Flexible Motions

The waist plays a crucial role in the agile movement of many animals in nature. It provides the torso with additional degrees of freedom and flexibility, inspiring researchers to incorporate this biological feature into robotic structures to enhance robot locomotion. This paper presents a cost-effective and low-complexity waist mechanism integrated into the structure of the open-source robot solo8, adding a new degree of freedom (DOF) to its torso. We refer to this novel robot as solo9. Additionally, we propose a full-body control method for the waist-equipped quadruped robot based on generative adversarial imitation learning (GAIL). During training, the discriminator is used as input for iterative optimization of the policy and dataset, enabling solo9 to achieve flexible steering maneuvers across various gaits. Extensive tests of solo9's steering capabilities, terrain adaptability, and robustness are conducted in both simulation and real-world scenarios, with detailed comparisons to solo8 and solo12, demonstrating the effectiveness of the control algorithm and the advantages of the waist mechanism.

Improving Factuality in Large Language Models via Decoding-Time Hallucinatory and Truthful Comparators

Despite their remarkable capabilities, Large Language Models (LLMs) are prone to generate responses that contradict verifiable facts, i.e., unfaithful hallucination content. Existing efforts generally focus on optimizing model parameters or editing semantic representations, which compromise the internal factual knowledge of target LLMs. In addition, hallucinations typically exhibit multifaceted patterns in downstream tasks, limiting the model's holistic performance across tasks. In this paper, we propose a Comparator-driven Decoding-Time (CDT) framework to alleviate the response hallucination. Firstly, we construct hallucinatory and truthful comparators with multi-task fine-tuning samples. In this case, we present an instruction prototype-guided mixture of experts strategy to enhance the ability of the corresponding comparators to capture different hallucination or truthfulness patterns in distinct task instructions. CDT constrains next-token predictions to factuality-robust distributions by contrasting the logit differences between the target LLMs and these comparators. Systematic experiments on multiple downstream tasks show that our framework can significantly improve the model performance and response factuality.