TractoRC: A Unified Probabilistic Learning Framework for Joint Tractography Registration and Clustering

Diffusion MRI tractography enables in vivo reconstruction of white matter (WM) pathways. Two key tasks in tractography analysis include: 1) tractogram registration that aligns streamlines across individuals, and 2) streamline clustering that groups streamlines into compact fiber bundles. Although both tasks share the goal of capturing geometrically similar structures to characterize consistent WM organization, they are typically performed independently. In this work, we propose TractoRC, a unified probabilistic framework that jointly performs tractogram registration and streamline clustering within a single optimization scheme, enabling the two tasks to leverage complementary information. TractoRC learns a latent embedding space for streamline points, which serves as a shared representation for both tasks. Within this space, both tasks are formulated as probabilistic inference over structural representations: registration learns the distribution of anatomical landmarks as probabilistic keypoints to align tractograms across subjects, and clustering learns streamline structural prototypes that capture geometric similarity to form coherent streamline clusters. To support effective learning of this shared space, we introduce a transformation-equivariant self-supervised strategy to learn geometry-aware and transformation-invariant embeddings. Experiments demonstrate that jointly optimizing registration and clustering significantly improves performance in both tasks over state-of-the-art methods that treat them independently. Code will be made publicly available at https://github.com/yishengpoxiao/TractoRC .

ExpPortrait: Expressive Portrait Generation via Personalized Representation

While diffusion models have shown great potential in portrait generation, generating expressive, coherent, and controllable cinematic portrait videos remains a significant challenge. Existing intermediate signals for portrait generation, such as 2D landmarks and parametric models, have limited disentanglement capabilities and cannot express personalized details due to their sparse or low-rank representation. Therefore, existing methods based on these models struggle to accurately preserve subject identity and expressions, hindering the generation of highly expressive portrait videos. To overcome these limitations, we propose a high-fidelity personalized head representation that more effectively disentangles expression and identity. This representation captures both static, subject-specific global geometry and dynamic, expression-related details. Furthermore, we introduce an expression transfer module to achieve personalized transfer of head pose and expression details between different identities. We use this sophisticated and highly expressive head model as a conditional signal to train a diffusion transformer (DiT)-based generator to synthesize richly detailed portrait videos. Extensive experiments on self- and cross-reenactment tasks demonstrate that our method outperforms previous models in terms of identity preservation, expression accuracy, and temporal stability, particularly in capturing fine-grained details of complex motion.

SpatialV2A: Visual-Guided High-fidelity Spatial Audio Generation

While video-to-audio generation has achieved remarkable progress in semantic and temporal alignment, most existing studies focus solely on these aspects, paying limited attention to the spatial perception and immersive quality of the synthesized audio. This limitation stems largely from current models' reliance on mono audio datasets, which lack the binaural spatial information needed to learn visual-to-spatial audio mappings. To address this gap, we introduce two key contributions: we construct BinauralVGGSound, the first large-scale video-binaural audio dataset designed to support spatially aware video-to-audio generation; and we propose a end-to-end spatial audio generation framework guided by visual cues, which explicitly models spatial features. Our framework incorporates a visual-guided audio spatialization module that ensures the generated audio exhibits realistic spatial attributes and layered spatial depth while maintaining semantic and temporal alignment. Experiments show that our approach substantially outperforms state-of-the-art models in spatial fidelity and delivers a more immersive auditory experience, without sacrificing temporal or semantic consistency. All datasets, code, and model checkpoints will be publicly released to facilitate future research.

Bridging Modalities: Joint Synthesis and Registration Framework for Aligning Diffusion MRI with T1-Weighted Images

Multimodal image registration between diffusion MRI (dMRI) and T1-weighted (T1w) MRI images is a critical step for aligning diffusion-weighted imaging (DWI) data with structural anatomical space. Traditional registration methods often struggle to ensure accuracy due to the large intensity differences between diffusion data and high-resolution anatomical structures. This paper proposes an unsupervised registration framework based on a generative registration network, which transforms the original multimodal registration problem between b0 and T1w images into a unimodal registration task between a generated image and the real T1w image. This effectively reduces the complexity of cross-modal registration. The framework first employs an image synthesis model to generate images with T1w-like contrast, and then learns a deformation field from the generated image to the fixed T1w image. The registration network jointly optimizes local structural similarity and cross-modal statistical dependency to improve deformation estimation accuracy. Experiments conducted on two independent datasets demonstrate that the proposed method outperforms several state-of-the-art approaches in multimodal registration tasks.

BrainSegNet: A Novel Framework for Whole-Brain MRI Parcellation Enhanced by Large Models

Whole-brain parcellation from MRI is a critical yet challenging task due to the complexity of subdividing the brain into numerous small, irregular shaped regions. Traditionally, template-registration methods were used, but recent advances have shifted to deep learning for faster workflows. While large models like the Segment Anything Model (SAM) offer transferable feature representations, they are not tailored for the high precision required in brain parcellation. To address this, we propose BrainSegNet, a novel framework that adapts SAM for accurate whole-brain parcellation into 95 regions. We enhance SAM by integrating U-Net skip connections and specialized modules into its encoder and decoder, enabling fine-grained anatomical precision. Key components include a hybrid encoder combining U-Net skip connections with SAM's transformer blocks, a multi-scale attention decoder with pyramid pooling for varying-sized structures, and a boundary refinement module to sharpen edges. Experimental results on the Human Connectome Project (HCP) dataset demonstrate that BrainSegNet outperforms several state-of-the-art methods, achieving higher accuracy and robustness in complex, multi-label parcellation.

PsychEval: A Multi-Session and Multi-Therapy Benchmark for High-Realism AI Psychological Counselor

To develop a reliable AI for psychological assessment, we introduce \texttt{PsychEval}, a multi-session, multi-therapy, and highly realistic benchmark designed to address three key challenges: \textbf{1) Can we train a highly realistic AI counselor?} Realistic counseling is a longitudinal task requiring sustained memory and dynamic goal tracking. We propose a multi-session benchmark (spanning 6-10 sessions across three distinct stages) that demands critical capabilities such as memory continuity, adaptive reasoning, and longitudinal planning. The dataset is annotated with extensive professional skills, comprising over 677 meta-skills and 4577 atomic skills. \textbf{2) How to train a multi-therapy AI counselor?} While existing models often focus on a single therapy, complex cases frequently require flexible strategies among various therapies. We construct a diverse dataset covering five therapeutic modalities (Psychodynamic, Behaviorism, CBT, Humanistic Existentialist, and Postmodernist) alongside an integrative therapy with a unified three-stage clinical framework across six core psychological topics. \textbf{3) How to systematically evaluate an AI counselor?} We establish a holistic evaluation framework with 18 therapy-specific and therapy-shared metrics across Client-Level and Counselor-Level dimensions. To support this, we also construct over 2,000 diverse client profiles. Extensive experimental analysis fully validates the superior quality and clinical fidelity of our dataset. Crucially, \texttt{PsychEval} transcends static benchmarking to serve as a high-fidelity reinforcement learning environment that enables the self-evolutionary training of clinically responsible and adaptive AI counselors.

AdaptFly: Prompt-Guided Adaptation of Foundation Models for Low-Altitude UAV Networks

Low-altitude Unmanned Aerial Vehicle (UAV) networks rely on robust semantic segmentation as a foundational enabler for distributed sensing-communication-control co-design across heterogeneous agents within the network. However, segmentation foundation models deteriorate quickly under weather, lighting, and viewpoint drift. Resource-limited UAVs cannot run gradient-based test-time adaptation, while resource-massive UAVs adapt independently, wasting shared experience. To address these challenges, we propose AdaptFly, a prompt-guided test-time adaptation framework that adjusts segmentation models without weight updates. AdaptFly features two complementary adaptation modes. For resource-limited UAVs, it employs lightweight token-prompt retrieval from a shared global memory. For resource-massive UAVs, it uses gradient-free sparse visual prompt optimization via Covariance Matrix Adaptation Evolution Strategy. An activation-statistic detector triggers adaptation, while cross-UAV knowledge pool consolidates prompt knowledge and enables fleet-wide collaboration with negligible bandwidth overhead. Extensive experiments on UAVid and VDD benchmarks, along with real-world UAV deployments under diverse weather conditions, demonstrate that AdaptFly significantly improves segmentation accuracy and robustness over static models and state-of-the-art TTA baselines. The results highlight a practical path to resilient, communication-efficient perception in the emerging low-altitude economy.

Coarse-to-Fine Joint Registration of MR and Ultrasound Images via Imaging Style Transfer

We developed a pipeline for registering pre-surgery Magnetic Resonance (MR) images and post-resection Ultrasound (US) images. Our approach leverages unpaired style transfer using 3D CycleGAN to generate synthetic T1 images, thereby enhancing registration performance. Additionally, our registration process employs both affine and local deformable transformations for a coarse-to-fine registration. The results demonstrate that our approach improves the consistency between MR and US image pairs in most cases.

Prototype-Driven Structure Synergy Network for Remote Sensing Images Segmentation

In the semantic segmentation of remote sensing images, acquiring complete ground objects is critical for achieving precise analysis. However, this task is severely hindered by two major challenges: high intra-class variance and high inter-class similarity. Traditional methods often yield incomplete segmentation results due to their inability to effectively unify class representations and distinguish between similar features. Even emerging class-guided approaches are limited by coarse class prototype representations and a neglect of target structural information. Therefore, this paper proposes a Prototype-Driven Structure Synergy Network (PDSSNet). The design of this network is based on a core concept, a complete ground object is jointly defined by its invariant class semantics and its variant spatial structure. To implement this, we have designed three key modules. First, the Adaptive Prototype Extraction Module (APEM) ensures semantic accuracy from the source by encoding the ground truth to extract unbiased class prototypes. Subsequently, the designed Semantic-Structure Coordination Module (SSCM) follows a hierarchical semantics-first, structure-second principle. This involves first establishing a global semantic cognition, then leveraging structural information to constrain and refine the semantic representation, thereby ensuring the integrity of class information. Finally, the Channel Similarity Adjustment Module (CSAM) employs a dynamic step-size adjustment mechanism to focus on discriminative features between classes. Extensive experiments demonstrate that PDSSNet outperforms state-of-the-art methods. The source code is available at https://github.com/wangjunyi-1/PDSSNet.

A Survey of Slow Thinking-based Reasoning LLMs using Reinforced Learning and Inference-time Scaling Law

This survey explores recent advancements in reasoning large language models (LLMs) designed to mimic "slow thinking" - a reasoning process inspired by human cognition, as described in Kahneman's Thinking, Fast and Slow. These models, like OpenAI's o1, focus on scaling computational resources dynamically during complex tasks, such as math reasoning, visual reasoning, medical diagnosis, and multi-agent debates. We present the development of reasoning LLMs and list their key technologies. By synthesizing over 100 studies, it charts a path toward LLMs that combine human-like deep thinking with scalable efficiency for reasoning. The review breaks down methods into three categories: (1) test-time scaling dynamically adjusts computation based on task complexity via search and sampling, dynamic verification; (2) reinforced learning refines decision-making through iterative improvement leveraging policy networks, reward models, and self-evolution strategies; and (3) slow-thinking frameworks (e.g., long CoT, hierarchical processes) that structure problem-solving with manageable steps. The survey highlights the challenges and further directions of this domain. Understanding and advancing the reasoning abilities of LLMs is crucial for unlocking their full potential in real-world applications, from scientific discovery to decision support systems.