A Novel Deep Learning Tractography Fiber Clustering Framework for Functionally Consistent White Matter Parcellation Using Multimodal Diffusion MRI and Functional MRI

Tractography fiber clustering using diffusion MRI (dMRI) is a crucial strategy for white matter (WM) parcellation. Current methods primarily use the geometric information of fibers (i.e., the spatial trajectories) to group similar fibers into clusters, overlooking the important functional signals present along the fiber tracts. There is increasing evidence that neural activity in the WM can be measured using functional MRI (fMRI), offering potentially valuable multimodal information for fiber clustering. In this paper, we develop a novel deep learning fiber clustering framework, namely Deep Multi-view Fiber Clustering (DMVFC), that uses joint dMRI and fMRI data to enable functionally consistent WM parcellation. DMVFC can effectively integrate the geometric characteristics of the WM fibers with the fMRI BOLD signals along the fiber tracts. It includes two major components: 1) a multi-view pretraining module to compute embedding features from fiber geometric information and functional signals separately, and 2) a collaborative fine-tuning module to simultaneously refine the two kinds of embeddings. In the experiments, we compare DMVFC with two state-of-the-art fiber clustering methods and demonstrate superior performance in achieving functionally meaningful and consistent WM parcellation results.

EasyJudge: an Easy-to-use Tool for Comprehensive Response Evaluation of LLMs

Recently, there has been a growing trend of employing large language models (LLMs) to judge the quality of other LLMs. Many studies have adopted closed-source models, mainly using GPT-4 as the evaluator. However, due to the closed-source nature of the GPT-4 model, employing it as an evaluator has resulted in issues including transparency, controllability, and cost-effectiveness. Some researchers have turned to using fine-tuned open-source LLMs as evaluators. However, existing open-source evaluation LLMs generally lack a user-friendly visualization tool, and they have not been optimized for accelerated model inference, which causes inconvenience for researchers with limited resources and those working across different fields. This paper presents EasyJudge, a model developed to evaluate significant language model responses. It is lightweight, precise, efficient, and user-friendly, featuring an intuitive visualization interface for ease of deployment and use. EasyJudge uses detailed datasets and refined prompts for model optimization, achieving strong consistency with human and proprietary model evaluations. The model optimized with quantitative methods enables EasyJudge to run efficiently on consumer-grade GPUs or even CPUs. We also provide detailed analysis and case studies to further reveal the potential of our method.

When Diffusion MRI Meets Diffusion Model: A Novel Deep Generative Model for Diffusion MRI Generation

Diffusion MRI (dMRI) is an advanced imaging technique characterizing tissue microstructure and white matter structural connectivity of the human brain. The demand for high-quality dMRI data is growing, driven by the need for better resolution and improved tissue contrast. However, acquiring high-quality dMRI data is expensive and time-consuming. In this context, deep generative modeling emerges as a promising solution to enhance image quality while minimizing acquisition costs and scanning time. In this study, we propose a novel generative approach to perform dMRI generation using deep diffusion models. It can generate high dimension (4D) and high resolution data preserving the gradients information and brain structure. We demonstrated our method through an image mapping task aimed at enhancing the quality of dMRI images from 3T to 7T. Our approach demonstrates highly enhanced performance in generating dMRI images when compared to the current state-of-the-art (SOTA) methods. This achievement underscores a substantial progression in enhancing dMRI quality, highlighting the potential of our novel generative approach to revolutionize dMRI imaging standards.

Multi-pass Training and Cross-information Fusion for Low-resource End-to-end Accented Speech Recognition

Low-resource accented speech recognition is one of the important challenges faced by current ASR technology in practical applications. In this study, we propose a Conformer-based architecture, called Aformer, to leverage both the acoustic information from large non-accented and limited accented training data. Specifically, a general encoder and an accent encoder are designed in the Aformer to extract complementary acoustic information. Moreover, we propose to train the Aformer in a multi-pass manner, and investigate three cross-information fusion methods to effectively combine the information from both general and accent encoders. All experiments are conducted on both the accented English and Mandarin ASR tasks. Results show that our proposed methods outperform the strong Conformer baseline by relative 10.2% to 24.5% word/character error rate reduction on six in-domain and out-of-domain accented test sets.

Selective Pseudo-labeling and Class-wise Discriminative Fusion for Sound Event Detection

In recent years, exploring effective sound separation (SSep) techniques to improve overlapping sound event detection (SED) attracts more and more attention. Creating accurate separation signals to avoid the catastrophic error accumulation during SED model training is very important and challenging. In this study, we first propose a novel selective pseudo-labeling approach, termed SPL, to produce high confidence separated target events from blind sound separation outputs. These target events are then used to fine-tune the original SED model that pre-trained on the sound mixtures in a multi-objective learning style. Then, to further leverage the SSep outputs, a class-wise discriminative fusion is proposed to improve the final SED performances, by combining multiple frame-level event predictions of both sound mixtures and their separated signals. All experiments are performed on the public DCASE 2021 Task 4 dataset, and results show that our approaches significantly outperforms the official baseline, the collar-based F 1, PSDS1 and PSDS2 performances are improved from 44.3%, 37.3% and 54.9% to 46.5%, 44.5% and 75.4%, respectively.

CNN-based Discriminative Training for Domain Compensation in Acoustic Event Detection with Frame-wise Classifier

Domain mismatch is a noteworthy issue in acoustic event detection tasks, as the target domain data is difficult to access in most real applications. In this study, we propose a novel CNN-based discriminative training framework as a domain compensation method to handle this issue. It uses a parallel CNN-based discriminator to learn a pair of high-level intermediate acoustic representations. Together with a binary discriminative loss, the discriminators are forced to maximally exploit the discrimination of heterogeneous acoustic information in each audio clip with target events, which results in a robust paired representations that can well discriminate the target events and background/domain variations separately. Moreover, to better learn the transient characteristics of target events, a frame-wise classifier is designed to perform the final classification. In addition, a two-stage training with the CNN-based discriminator initialization is further proposed to enhance the system training. All experiments are performed on the DCASE 2018 Task3 datasets. Results show that our proposal significantly outperforms the official baseline on cross-domain conditions in AUC by relative $1.8-12.1$% without any performance degradation on in-domain evaluation conditions.

Joint Weakly Supervised AT and AED Using Deep Feature Distillation and Adaptive Focal Loss

A good joint training framework is very helpful to improve the performances of weakly supervised audio tagging (AT) and acoustic event detection (AED) simultaneously. In this study, we propose three methods to improve the best teacher-student framework of DCASE2019 Task 4 for both AT and AED tasks. A frame-level target-events based deep feature distillation is first proposed, it aims to leverage the potential of limited strong-labeled data in weakly supervised framework to learn better intermediate feature maps. Then we propose an adaptive focal loss and two-stage training strategy to enable an effective and more accurate model training, in which the contribution of difficult-to-classify and easy-to-classify acoustic events to the total cost function can be automatically adjusted. Furthermore, an event-specific post processing is designed to improve the prediction of target event time-stamps. Our experiments are performed on the public DCASE2019 Task4 dataset, and results show that our approach achieves competitive performances in both AT (49.8% F1-score) and AED (81.2% F1-score) tasks.