White-Box Diffusion Transformer for single-cell RNA-seq generation

As a powerful tool for characterizing cellular subpopulations and cellular heterogeneity, single cell RNA sequencing (scRNA-seq) technology offers advantages of high throughput and multidimensional analysis. However, the process of data acquisition is often constrained by high cost and limited sample availability. To overcome these limitations, we propose a hybrid model based on Diffusion model and White-Box transformer that aims to generate synthetic and biologically plausible scRNA-seq data. Diffusion model progressively introduce noise into the data and then recover the original data through a denoising process, a forward and reverse process that is particularly suitable for generating complex data distributions. White-Box transformer is a deep learning architecture that emphasizes mathematical interpretability. By minimizing the encoding rate of the data and maximizing the sparsity of the representation, it not only reduces the computational burden, but also provides clear insight into underlying structure. Our White-Box Diffusion Transformer combines the generative capabilities of Diffusion model with the mathematical interpretability of White-Box transformer. Through experiments using six different single-cell RNA-Seq datasets, we visualize both generated and real data using t-SNE dimensionality reduction technique, as well as quantify similarity between generated and real data using various metrics to demonstrate comparable performance of White-Box Diffusion Transformer and Diffusion Transformer in generating scRNA-seq data alongside significant improvements in training efficiency and resource utilization. Our code is available at https://github.com/lingximamo/White-Box-Diffusion-Transformer

Adaptive Caching for Faster Video Generation with Diffusion Transformers

Generating temporally-consistent high-fidelity videos can be computationally expensive, especially over longer temporal spans. More-recent Diffusion Transformers (DiTs) -- despite making significant headway in this context -- have only heightened such challenges as they rely on larger models and heavier attention mechanisms, resulting in slower inference speeds. In this paper, we introduce a training-free method to accelerate video DiTs, termed Adaptive Caching (AdaCache), which is motivated by the fact that "not all videos are created equal": meaning, some videos require fewer denoising steps to attain a reasonable quality than others. Building on this, we not only cache computations through the diffusion process, but also devise a caching schedule tailored to each video generation, maximizing the quality-latency trade-off. We further introduce a Motion Regularization (MoReg) scheme to utilize video information within AdaCache, essentially controlling the compute allocation based on motion content. Altogether, our plug-and-play contributions grant significant inference speedups (e.g. up to 4.7x on Open-Sora 720p - 2s video generation) without sacrificing the generation quality, across multiple video DiT baselines.

MarDini: Masked Autoregressive Diffusion for Video Generation at Scale

We introduce MarDini, a new family of video diffusion models that integrate the advantages of masked auto-regression (MAR) into a unified diffusion model (DM) framework. Here, MAR handles temporal planning, while DM focuses on spatial generation in an asymmetric network design: i) a MAR-based planning model containing most of the parameters generates planning signals for each masked frame using low-resolution input; ii) a lightweight generation model uses these signals to produce high-resolution frames via diffusion de-noising. MarDini's MAR enables video generation conditioned on any number of masked frames at any frame positions: a single model can handle video interpolation (e.g., masking middle frames), image-to-video generation (e.g., masking from the second frame onward), and video expansion (e.g., masking half the frames). The efficient design allocates most of the computational resources to the low-resolution planning model, making computationally expensive but important spatio-temporal attention feasible at scale. MarDini sets a new state-of-the-art for video interpolation; meanwhile, within few inference steps, it efficiently generates videos on par with those of much more expensive advanced image-to-video models.

Matrix Multiplication on Quantum Computer

This paper introduces an innovative and practical approach to universal quantum matrix multiplication. We designed optimized quantum adders and multipliers based on Quantum Fourier Transform (QFT), which significantly reduced the number of gates used compared to classical adders and multipliers. Subsequently, we construct a basic universal quantum matrix multiplication and extend it to the Strassen algorithm. We conduct comparative experiments to analyze the performance of the quantum matrix multiplication and evaluate the acceleration provided by the optimized quantum adder and multiplier. Furthermore, we investigate the advantages and disadvantages of the quantum Strassen algorithm compared to basic quantum matrix multiplication.

scRDiT: Generating single-cell RNA-seq data by diffusion transformers and accelerating sampling

Motivation: Single-cell RNA sequencing (scRNA-seq) is a groundbreaking technology extensively utilized in biological research, facilitating the examination of gene expression at the individual cell level within a given tissue sample. While numerous tools have been developed for scRNA-seq data analysis, the challenge persists in capturing the distinct features of such data and replicating virtual datasets that share analogous statistical properties. Results: Our study introduces a generative approach termed scRNA-seq Diffusion Transformer (scRDiT). This method generates virtual scRNA-seq data by leveraging a real dataset. The method is a neural network constructed based on Denoising Diffusion Probabilistic Models (DDPMs) and Diffusion Transformers (DiTs). This involves subjecting Gaussian noises to the real dataset through iterative noise-adding steps and ultimately restoring the noises to form scRNA-seq samples. This scheme allows us to learn data features from actual scRNA-seq samples during model training. Our experiments, conducted on two distinct scRNA-seq datasets, demonstrate superior performance. Additionally, the model sampling process is expedited by incorporating Denoising Diffusion Implicit Models (DDIM). scRDiT presents a unified methodology empowering users to train neural network models with their unique scRNA-seq datasets, enabling the generation of numerous high-quality scRNA-seq samples. Availability and implementation: https://github.com/DongShengze/scRDiT

Graphy Analysis Using a GPU-based Parallel Algorithm: Quantum Clustering

The article introduces a new method for applying Quantum Clustering to graph structures. Quantum Clustering (QC) is a novel density-based unsupervised learning method that determines cluster centers by constructing a potential function. In this method, we use the Graph Gradient Descent algorithm to find the centers of clusters. GPU parallelization is utilized for computing potential values. We also conducted experiments on five widely used datasets and evaluated using four indicators. The results show superior performance of the method. Finally, we discuss the influence of $\sigma$ on the experimental results.

Hierarchical Integration Diffusion Model for Realistic Image Deblurring

Diffusion models (DMs) have recently been introduced in image deblurring and exhibited promising performance, particularly in terms of details reconstruction. However, the diffusion model requires a large number of inference iterations to recover the clean image from pure Gaussian noise, which consumes massive computational resources. Moreover, the distribution synthesized by the diffusion model is often misaligned with the target results, leading to restrictions in distortion-based metrics. To address the above issues, we propose the Hierarchical Integration Diffusion Model (HI-Diff), for realistic image deblurring. Specifically, we perform the DM in a highly compacted latent space to generate the prior feature for the deblurring process. The deblurring process is implemented by a regression-based method to obtain better distortion accuracy. Meanwhile, the highly compact latent space ensures the efficiency of the DM. Furthermore, we design the hierarchical integration module to fuse the prior into the regression-based model from multiple scales, enabling better generalization in complex blurry scenarios. Comprehensive experiments on synthetic and real-world blur datasets demonstrate that our HI-Diff outperforms state-of-the-art methods. Code and trained models are available at https://github.com/zhengchen1999/HI-Diff.

ShadowFormer: Global Context Helps Image Shadow Removal

Recent deep learning methods have achieved promising results in image shadow removal. However, most of the existing approaches focus on working locally within shadow and non-shadow regions, resulting in severe artifacts around the shadow boundaries as well as inconsistent illumination between shadow and non-shadow regions. It is still challenging for the deep shadow removal model to exploit the global contextual correlation between shadow and non-shadow regions. In this work, we first propose a Retinex-based shadow model, from which we derive a novel transformer-based network, dubbed ShandowFormer, to exploit non-shadow regions to help shadow region restoration. A multi-scale channel attention framework is employed to hierarchically capture the global information. Based on that, we propose a Shadow-Interaction Module (SIM) with Shadow-Interaction Attention (SIA) in the bottleneck stage to effectively model the context correlation between shadow and non-shadow regions. We conduct extensive experiments on three popular public datasets, including ISTD, ISTD+, and SRD, to evaluate the proposed method. Our method achieves state-of-the-art performance by using up to 150X fewer model parameters.

AIM 2022 Challenge on Super-Resolution of Compressed Image and Video: Dataset, Methods and Results

This paper reviews the Challenge on Super-Resolution of Compressed Image and Video at AIM 2022. This challenge includes two tracks. Track 1 aims at the super-resolution of compressed image, and Track~2 targets the super-resolution of compressed video. In Track 1, we use the popular dataset DIV2K as the training, validation and test sets. In Track 2, we propose the LDV 3.0 dataset, which contains 365 videos, including the LDV 2.0 dataset (335 videos) and 30 additional videos. In this challenge, there are 12 teams and 2 teams that submitted the final results to Track 1 and Track 2, respectively. The proposed methods and solutions gauge the state-of-the-art of super-resolution on compressed image and video. The proposed LDV 3.0 dataset is available at https://github.com/RenYang-home/LDV_dataset. The homepage of this challenge is at https://github.com/RenYang-home/AIM22_CompressSR.

Boosting Video Super Resolution with Patch-Based Temporal Redundancy Optimization

The success of existing video super-resolution (VSR) algorithms stems mainly exploiting the temporal information from the neighboring frames. However, none of these methods have discussed the influence of the temporal redundancy in the patches with stationary objects and background and usually use all the information in the adjacent frames without any discrimination. In this paper, we observe that the temporal redundancy will bring adverse effect to the information propagation,which limits the performance of the most existing VSR methods. Motivated by this observation, we aim to improve existing VSR algorithms by handling the temporal redundancy patches in an optimized manner. We develop two simple yet effective plug and play methods to improve the performance of existing local and non-local propagation-based VSR algorithms on widely-used public videos. For more comprehensive evaluating the robustness and performance of existing VSR algorithms, we also collect a new dataset which contains a variety of public videos as testing set. Extensive evaluations show that the proposed methods can significantly improve the performance of existing VSR methods on the collected videos from wild scenarios while maintain their performance on existing commonly used datasets. The code is available at https://github.com/HYHsimon/Boosted-VSR.