AI in Oncology: Transforming Cancer Detection through Machine Learning and Deep Learning Applications

Artificial intelligence (AI) has potential to revolutionize the field of oncology by enhancing the precision of cancer diagnosis, optimizing treatment strategies, and personalizing therapies for a variety of cancers. This review examines the limitations of conventional diagnostic techniques and explores the transformative role of AI in diagnosing and treating cancers such as lung, breast, colorectal, liver, stomach, esophageal, cervical, thyroid, prostate, and skin cancers. The primary objective of this paper is to highlight the significant advancements that AI algorithms have brought to oncology within the medical industry. By enabling early cancer detection, improving diagnostic accuracy, and facilitating targeted treatment delivery, AI contributes to substantial improvements in patient outcomes. The integration of AI in medical imaging, genomic analysis, and pathology enhances diagnostic precision and introduces a novel, less invasive approach to cancer screening. This not only boosts the effectiveness of medical facilities but also reduces operational costs. The study delves into the application of AI in radiomics for detailed cancer characterization, predictive analytics for identifying associated risks, and the development of algorithm-driven robots for immediate diagnosis. Furthermore, it investigates the impact of AI on addressing healthcare challenges, particularly in underserved and remote regions. The overarching goal of this platform is to support the development of expert recommendations and to provide universal, efficient diagnostic procedures. By reviewing existing research and clinical studies, this paper underscores the pivotal role of AI in improving the overall cancer care system. It emphasizes how AI-enabled systems can enhance clinical decision-making and expand treatment options, thereby underscoring the importance of AI in advancing precision oncology

Hybrid Interpretable Deep Learning Framework for Skin Cancer Diagnosis: Integrating Radial Basis Function Networks with Explainable AI

Skin cancer is one of the most prevalent and potentially life-threatening diseases worldwide, necessitating early and accurate diagnosis to improve patient outcomes. Conventional diagnostic methods, reliant on clinical expertise and histopathological analysis, are often time-intensive, subjective, and prone to variability. To address these limitations, we propose a novel hybrid deep learning framework that integrates convolutional neural networks (CNNs) with Radial Basis Function (RBF) Networks to achieve high classification accuracy and enhanced interpretability. The motivation for incorporating RBF Networks lies in their intrinsic interpretability and localized response to input features, which make them well-suited for tasks requiring transparency and fine-grained decision-making. Unlike traditional deep learning models that rely on global feature representations, RBF Networks allow for mapping segments of images to chosen prototypes, exploiting salient features within a single image. This enables clinicians to trace predictions to specific, interpretable patterns. The framework incorporates segmentation-based feature extraction, active learning for prototype selection, and K-Medoids clustering to focus on these salient features. Evaluations on the ISIC 2016 and ISIC 2017 datasets demonstrate the model's effectiveness, achieving classification accuracies of 83.02\% and 72.15\% using ResNet50, respectively, and outperforming VGG16-based configurations. By generating interpretable explanations for predictions, the framework aligns with clinical workflows, bridging the gap between predictive performance and trustworthiness. This study highlights the potential of hybrid models to deliver actionable insights, advancing the development of reliable AI-assisted diagnostic tools for high-stakes medical applications.

Enhancing Medical Image Analysis through Geometric and Photometric transformations

Medical image analysis suffers from a lack of labeled data due to several challenges including patient privacy and lack of experts. Although some AI models only perform well with large amounts of data, we will move to data augmentation where there is a solution to improve the performance of our models and increase the dataset size through traditional or advanced techniques. In this paper, we evaluate the effectiveness of data augmentation techniques on two different medical image datasets. In the first step, we applied some transformation techniques to the skin cancer dataset containing benign and malignant classes. Then, we trained the convolutional neural network (CNN) on the dataset before and after augmentation, which significantly improved test accuracy from 90.74% to 96.88% and decreased test loss from 0.7921 to 0.1468 after augmentation. In the second step, we used the Mixup technique by mixing two random images and their corresponding masks using the retina and blood vessels dataset, then we trained the U-net model and obtained the Dice coefficient which increased from 0 before augmentation to 0.4163 after augmentation. The result shows the effect of using data augmentation to increase the dataset size on the classification and segmentation performance.

Skin Disease Detection and Classification of Actinic Keratosis and Psoriasis Utilizing Deep Transfer Learning

Skin diseases can arise from infections, allergies, genetic factors, autoimmune disorders, hormonal imbalances, or environmental triggers such as sun damage and pollution. Some skin diseases, such as Actinic Keratosis and Psoriasis, can be fatal if not treated in time. Early identification is crucial, but the diagnostic methods for these conditions are often expensive and not widely accessible. In this study, we propose a novel and efficient method for diagnosing skin diseases using deep learning techniques. This approach employs a modified VGG16 Convolutional Neural Network (CNN) model. The model includes several convolutional layers and utilizes ImageNet weights with modified top layers. The top layer is updated with fully connected layers and a final softmax activation layer to classify skin diseases. The dataset used, titled "Skin Disease Dataset," is publicly available. While the VGG16 architecture does not include data augmentation by default, preprocessing techniques such as rotation, shifting, and zooming were applied to augment the data prior to model training. The proposed methodology achieved 90.67% accuracy using the modified VGG16 model, demonstrating its reliability in classifying skin diseases. The promising results highlight the potential of this approach for real-world applications.

BlanketGen2-Fit3D: Synthetic Blanket Augmentation Towards Improving Real-World In-Bed Blanket Occluded Human Pose Estimation

Human Pose Estimation (HPE) from monocular RGB images is crucial for clinical in-bed skeleton-based action recognition, however, it poses unique challenges for HPE models due to the frequent presence of blankets occluding the person, while labeled HPE data in this scenario is scarce. To address this we introduce BlanketGen2-Fit3D (BG2-Fit3D), an augmentation of Fit3D dataset that contains 1,217,312 frames with synthetic photo-realistic blankets. To generate it we used BlanketGen2, our new and improved version of our BlanketGen pipeline that simulates synthetic blankets using ground-truth Skinned Multi-Person Linear model (SMPL) meshes and then renders them as transparent images that can be layered on top of the original frames. This dataset was used in combination with the original Fit3D to finetune the ViTPose-B HPE model, to evaluate synthetic blanket augmentation effectiveness. The trained models were further evaluated on a real-world blanket occluded in-bed HPE dataset (SLP dataset). Comparing architectures trained on only Fit3D with the ones trained with our synthetic blanket augmentation the later improved pose estimation performance on BG2-Fit3D, the synthetic blanket occluded dataset significantly to (0.977 Percentage of Correct Keypoints (PCK), 0.149 Normalized Mean Error (NME)) with an absolute 4.4% PCK increase. Furthermore, the test results on SLP demonstrated the utility of synthetic data augmentation by improving performance by an absolute 2.3% PCK, on real-world images with the poses occluded by real blankets. These results show synthetic blanket augmentation has the potential to improve in-bed blanket occluded HPE from RGB images. The dataset as well as the code will be made available to the public.

Are generative models fair? A study of racial bias in dermatological image generation

Racial bias in medicine, particularly in dermatology, presents significant ethical and clinical challenges. It often results from the underrepresentation of darker skin tones in training datasets for machine learning models. While efforts to address bias in dermatology have focused on improving dataset diversity and mitigating disparities in discriminative models, the impact of racial bias on generative models remains underexplored. Generative models, such as Variational Autoencoders (VAEs), are increasingly used in healthcare applications, yet their fairness across diverse skin tones is currently not well understood. In this study, we evaluate the fairness of generative models in clinical dermatology with respect to racial bias. For this purpose, we first train a VAE with a perceptual loss to generate and reconstruct high-quality skin images across different skin tones. We utilize the Fitzpatrick17k dataset to examine how racial bias influences the representation and performance of these models. Our findings indicate that the VAE is influenced by the diversity of skin tones in the training dataset, with better performance observed for lighter skin tones. Additionally, the uncertainty estimates produced by the VAE are ineffective in assessing the model's fairness. These results highlight the need for improved uncertainty quantification mechanisms to detect and address racial bias in generative models for trustworthy healthcare technologies.

Make-A-Character 2: Animatable 3D Character Generation From a Single Image

This report introduces Make-A-Character 2, an advanced system for generating high-quality 3D characters from single portrait photographs, ideal for game development and digital human applications. Make-A-Character 2 builds upon its predecessor by incorporating several significant improvements for image-based head generation. We utilize the IC-Light method to correct non-ideal illumination in input photos and apply neural network-based color correction to harmonize skin tones between the photos and game engine renders. We also employ the Hierarchical Representation Network to capture high-frequency facial structures and conduct adaptive skeleton calibration for accurate and expressive facial animations. The entire image-to-3D-character generation process takes less than 2 minutes. Furthermore, we leverage transformer architecture to generate co-speech facial and gesture actions, enabling real-time conversation with the generated character. These technologies have been integrated into our conversational AI avatar products.

An analysis of data variation and bias in image-based dermatological datasets for machine learning classification

AI algorithms have become valuable in aiding professionals in healthcare. The increasing confidence obtained by these models is helpful in critical decision demands. In clinical dermatology, classification models can detect malignant lesions on patients' skin using only RGB images as input. However, most learning-based methods employ data acquired from dermoscopic datasets on training, which are large and validated by a gold standard. Clinical models aim to deal with classification on users' smartphone cameras that do not contain the corresponding resolution provided by dermoscopy. Also, clinical applications bring new challenges. It can contain captures from uncontrolled environments, skin tone variations, viewpoint changes, noises in data and labels, and unbalanced classes. A possible alternative would be to use transfer learning to deal with the clinical images. However, as the number of samples is low, it can cause degradations on the model's performance; the source distribution used in training differs from the test set. This work aims to evaluate the gap between dermoscopic and clinical samples and understand how the dataset variations impact training. It assesses the main differences between distributions that disturb the model's prediction. Finally, from experiments on different architectures, we argue how to combine the data from divergent distributions, decreasing the impact on the model's final accuracy.

Lights, Camera, Matching: The Role of Image Illumination in Fair Face Recognition

Facial brightness is a key image quality factor impacting face recognition accuracy differentials across demographic groups. In this work, we aim to decrease the accuracy gap between the similarity score distributions for Caucasian and African American female mated image pairs, as measured by d' between distributions. To balance brightness across demographic groups, we conduct three experiments, interpreting brightness in the face skin region either as median pixel value or as the distribution of pixel values. Balancing based on median brightness alone yields up to a 46.8% decrease in d', while balancing based on brightness distribution yields up to a 57.6% decrease. In all three cases, the similarity scores of the individual distributions improve, with mean scores maximally improving 5.9% for Caucasian females and 3.7% for African American females.

Demographic Variability in Face Image Quality Measures

Face image quality assessment (FIQA) algorithms are being integrated into online identity management applications. These applications allow users to upload a face image as part of their document issuance process, where the image is then run through a quality assessment process to make sure it meets the quality and compliance requirements. Concerns about demographic bias have been raised about biometric systems, given the societal implications this may cause. It is therefore important that demographic variability in FIQA algorithms is assessed such that mitigation measures can be created. In this work, we study the demographic variability of all face image quality measures included in the ISO/IEC 29794-5 international standard across three demographic variables: age, gender, and skin tone. The results are rather promising and show no clear bias toward any specific demographic group for most measures. Only two quality measures are found to have considerable variations in their outcomes for different groups on the skin tone variable.