Single-cell Curriculum Learning-based Deep Graph Embedding Clustering

The swift advancement of single-cell RNA sequencing (scRNA-seq) technologies enables the investigation of cellular-level tissue heterogeneity. Cell annotation significantly contributes to the extensive downstream analysis of scRNA-seq data. However, The analysis of scRNA-seq for biological inference presents challenges owing to its intricate and indeterminate data distribution, characterized by a substantial volume and a high frequency of dropout events. Furthermore, the quality of training samples varies greatly, and the performance of the popular scRNA-seq data clustering solution GNN could be harmed by two types of low-quality training nodes: 1) nodes on the boundary; 2) nodes that contribute little additional information to the graph. To address these problems, we propose a single-cell curriculum learning-based deep graph embedding clustering (scCLG). We first propose a Chebyshev graph convolutional autoencoder with multi-decoder (ChebAE) that combines three optimization objectives corresponding to three decoders, including topology reconstruction loss of cell graphs, zero-inflated negative binomial (ZINB) loss, and clustering loss, to learn cell-cell topology representation. Meanwhile, we employ a selective training strategy to train GNN based on the features and entropy of nodes and prune the difficult nodes based on the difficulty scores to keep the high-quality graph. Empirical results on a variety of gene expression datasets show that our model outperforms state-of-the-art methods.

Learning High-resolution Vector Representation from Multi-Camera Images for 3D Object Detection

The Bird's-Eye-View (BEV) representation is a critical factor that directly impacts the 3D object detection performance, but the traditional BEV grid representation induces quadratic computational cost as the spatial resolution grows. To address this limitation, we present a new camera-based 3D object detector with high-resolution vector representation: VectorFormer. The presented high-resolution vector representation is combined with the lower-resolution BEV representation to efficiently exploit 3D geometry from multi-camera images at a high resolution through our two novel modules: vector scattering and gathering. To this end, the learned vector representation with richer scene contexts can serve as the decoding query for final predictions. We conduct extensive experiments on the nuScenes dataset and demonstrate state-of-the-art performance in NDS and inference time. Furthermore, we investigate query-BEV-based methods incorporated with our proposed vector representation and observe a consistent performance improvement.

Cross-Cluster Shifting for Efficient and Effective 3D Object Detection in Autonomous Driving

We present a new 3D point-based detector model, named Shift-SSD, for precise 3D object detection in autonomous driving. Traditional point-based 3D object detectors often employ architectures that rely on a progressive downsampling of points. While this method effectively reduces computational demands and increases receptive fields, it will compromise the preservation of crucial non-local information for accurate 3D object detection, especially in the complex driving scenarios. To address this, we introduce an intriguing Cross-Cluster Shifting operation to unleash the representation capacity of the point-based detector by efficiently modeling longer-range inter-dependency while including only a negligible overhead. Concretely, the Cross-Cluster Shifting operation enhances the conventional design by shifting partial channels from neighboring clusters, which enables richer interaction with non-local regions and thus enlarges the receptive field of clusters. We conduct extensive experiments on the KITTI, Waymo, and nuScenes datasets, and the results demonstrate the state-of-the-art performance of Shift-SSD in both detection accuracy and runtime efficiency.

DeepEMplanner: An End-to-End EM Motion Planner with Iterative Interactions

Motion planning is a computational problem that finds a sequence of valid trajectories, often based on surrounding agents' forecasting, environmental understanding, and historical and future contexts. It can also be viewed as a game in which agents continuously plan their next move according to other agents' intentions and the encountering environment, further achieving their ultimate goals through incremental actions. To model the dynamic planning and interaction process, we propose a novel framework, DeepEMplanner, which takes the stepwise interaction into account for fine-grained behavior learning. The ego vehicle maximizes each step motion to reach its eventual driving outcome based on the stepwise expectation from agents and its upcoming road conditions. On the other hand, the agents also follow the same philosophy to maximize their stepwise behavior under the encountering environment and the expectations from ego and other agents. Our DeepEMplanner models the interactions among ego, agents, and the dynamic environment in an autoregressive manner by interleaving the Expectation and Maximization processes. Further, we design ego-to-agents, ego-to-map, and ego-to-BEV interaction mechanisms with hierarchical dynamic key objects attention to better model the interactions. Experiments on the nuScenes benchmark show that our approach achieves state-of-the-art results.

DPSUR: Accelerating Differentially Private Stochastic Gradient Descent Using Selective Update and Release

Machine learning models are known to memorize private data to reduce their training loss, which can be inadvertently exploited by privacy attacks such as model inversion and membership inference. To protect against these attacks, differential privacy (DP) has become the de facto standard for privacy-preserving machine learning, particularly those popular training algorithms using stochastic gradient descent, such as DPSGD. Nonetheless, DPSGD still suffers from severe utility loss due to its slow convergence. This is partially caused by the random sampling, which brings bias and variance to the gradient, and partially by the Gaussian noise, which leads to fluctuation of gradient updates. Our key idea to address these issues is to apply selective updates to the model training, while discarding those useless or even harmful updates. Motivated by this, this paper proposes DPSUR, a Differentially Private training framework based on Selective Updates and Release, where the gradient from each iteration is evaluated based on a validation test, and only those updates leading to convergence are applied to the model. As such, DPSUR ensures the training in the right direction and thus can achieve faster convergence than DPSGD. The main challenges lie in two aspects -- privacy concerns arising from gradient evaluation, and gradient selection strategy for model update. To address the challenges, DPSUR introduces a clipping strategy for update randomization and a threshold mechanism for gradient selection. Experiments conducted on MNIST, FMNIST, CIFAR-10, and IMDB datasets show that DPSUR significantly outperforms previous works in terms of convergence speed and model utility.

DP-DCAN: Differentially Private Deep Contrastive Autoencoder Network for Single-cell Clustering

Single-cell RNA sequencing (scRNA-seq) is important to transcriptomic analysis of gene expression. Recently, deep learning has facilitated the analysis of high-dimensional single-cell data. Unfortunately, deep learning models may leak sensitive information about users. As a result, Differential Privacy (DP) is increasingly used to protect privacy. However, existing DP methods usually perturb whole neural networks to achieve differential privacy, and hence result in great performance overheads. To address this challenge, in this paper, we take advantage of the uniqueness of the autoencoder that it outputs only the dimension-reduced vector in the middle of the network, and design a Differentially Private Deep Contrastive Autoencoder Network (DP-DCAN) by partial network perturbation for single-cell clustering. Since only partial network is added with noise, the performance improvement is obvious and twofold: one part of network is trained with less noise due to a bigger privacy budget, and the other part is trained without any noise. Experimental results of six datasets have verified that DP-DCAN is superior to the traditional DP scheme with whole network perturbation. Moreover, DP-DCAN demonstrates strong robustness to adversarial attacks. The code is available at https://github.com/LFD-byte/DP-DCAN.

Adaptive Local Steps Federated Learning with Differential Privacy Driven by Convergence Analysis

Federated Learning (FL) is a distributed machine learning technique that allows model training among multiple devices or organizations without sharing data. However, while FL ensures that the raw data is not directly accessible to external adversaries, adversaries can still obtain some statistical information about the data through differential attacks. Differential Privacy (DP) has been proposed, which adds noise to the model or gradients to prevent adversaries from inferring private information from the transmitted parameters. We reconsider the framework of differential privacy federated learning in resource-constrained scenarios (privacy budget and communication resources). We analyze the convergence of federated learning with differential privacy (DPFL) on resource-constrained scenarios and propose an Adaptive Local Steps Differential Privacy Federated Learning (ALS-DPFL) algorithm. We experiment our algorithm on the FashionMNIST and Cifar-10 datasets and achieve quite good performance relative to previous work.

Adap DP-FL: Differentially Private Federated Learning with Adaptive Noise

Federated learning seeks to address the issue of isolated data islands by making clients disclose only their local training models. However, it was demonstrated that private information could still be inferred by analyzing local model parameters, such as deep neural network model weights. Recently, differential privacy has been applied to federated learning to protect data privacy, but the noise added may degrade the learning performance much. Typically, in previous work, training parameters were clipped equally and noises were added uniformly. The heterogeneity and convergence of training parameters were simply not considered. In this paper, we propose a differentially private scheme for federated learning with adaptive noise (Adap DP-FL). Specifically, due to the gradient heterogeneity, we conduct adaptive gradient clipping for different clients and different rounds; due to the gradient convergence, we add decreasing noises accordingly. Extensive experiments on real-world datasets demonstrate that our Adap DP-FL outperforms previous methods significantly.

SA-DPSGD: Differentially Private Stochastic Gradient Descent based on Simulated Annealing

Differential privacy (DP) provides a formal privacy guarantee that prevents adversaries with access to machine learning models from extracting information about individual training points. Differentially private stochastic gradient descent (DPSGD) is the most popular training method with differential privacy in image recognition. However, existing DPSGD schemes lead to significant performance degradation, which prevents the application of differential privacy. In this paper, we propose a simulated annealing-based differentially private stochastic gradient descent scheme (SA-DPSGD) which accepts a candidate update with a probability that depends both on the update quality and on the number of iterations. Through this random update screening, we make the differentially private gradient descent proceed in the right direction in each iteration, and result in a more accurate model finally. In our experiments, under the same hyperparameters, our scheme achieves test accuracies 98.35%, 87.41% and 60.92% on datasets MNIST, FashionMNIST and CIFAR10, respectively, compared to the state-of-the-art result of 98.12%, 86.33% and 59.34%. Under the freely adjusted hyperparameters, our scheme achieves even higher accuracies, 98.89%, 88.50% and 64.17%. We believe that our method has a great contribution for closing the accuracy gap between private and non-private image classification.

Point Cloud Compression with Sibling Context and Surface Priors

We present a novel octree-based multi-level framework for large-scale point cloud compression, which can organize sparse and unstructured point clouds in a memory-efficient way. In this framework, we propose a new entropy model that explores the hierarchical dependency in an octree using the context of siblings' children, ancestors, and neighbors to encode the occupancy information of each non-leaf octree node into a bitstream. Moreover, we locally fit quadratic surfaces with a voxel-based geometry-aware module to provide geometric priors in entropy encoding. These strong priors empower our entropy framework to encode the octree into a more compact bitstream. In the decoding stage, we apply a two-step heuristic strategy to restore point clouds with better reconstruction quality. The quantitative evaluation shows that our method outperforms state-of-the-art baselines with a bitrate improvement of 11-16% and 12-14% on the KITTI Odometry and nuScenes datasets, respectively.