Image Synthesis with Class-Aware Semantic Diffusion Models for Surgical Scene Segmentation

Surgical scene segmentation is essential for enhancing surgical precision, yet it is frequently compromised by the scarcity and imbalance of available data. To address these challenges, semantic image synthesis methods based on generative adversarial networks and diffusion models have been developed. However, these models often yield non-diverse images and fail to capture small, critical tissue classes, limiting their effectiveness. In response, we propose the Class-Aware Semantic Diffusion Model (CASDM), a novel approach which utilizes segmentation maps as conditions for image synthesis to tackle data scarcity and imbalance. Novel class-aware mean squared error and class-aware self-perceptual loss functions have been defined to prioritize critical, less visible classes, thereby enhancing image quality and relevance. Furthermore, to our knowledge, we are the first to generate multi-class segmentation maps using text prompts in a novel fashion to specify their contents. These maps are then used by CASDM to generate surgical scene images, enhancing datasets for training and validating segmentation models. Our evaluation, which assesses both image quality and downstream segmentation performance, demonstrates the strong effectiveness and generalisability of CASDM in producing realistic image-map pairs, significantly advancing surgical scene segmentation across diverse and challenging datasets.

Quantum Neural Network for Accelerated Magnetic Resonance Imaging

Magnetic resonance image reconstruction starting from undersampled k-space data requires the recovery of many potential nonlinear features, which is very difficult for algorithms to recover these features. In recent years, the development of quantum computing has discovered that quantum convolution can improve network accuracy, possibly due to potential quantum advantages. This article proposes a hybrid neural network containing quantum and classical networks for fast magnetic resonance imaging, and conducts experiments on a quantum computer simulation system. The experimental results indicate that the hybrid network has achieved excellent reconstruction results, and also confirm the feasibility of applying hybrid quantum-classical neural networks into the image reconstruction of rapid magnetic resonance imaging.

Optimized Magnetic Resonance Fingerprinting Using Ziv-Zakai Bound

Magnetic Resonance Fingerprinting (MRF) has emerged as a promising quantitative imaging technique within the field of Magnetic Resonance Imaging (MRI), offers comprehensive insights into tissue properties by simultaneously acquiring multiple tissue parameter maps in a single acquisition. Sequence optimization is crucial for improving the accuracy and efficiency of MRF. In this work, a novel framework for MRF sequence optimization is proposed based on the Ziv-Zakai bound (ZZB). Unlike the Cram\'er-Rao bound (CRB), which aims to enhance the quality of a single fingerprint signal with deterministic parameters, ZZB provides insights into evaluating the minimum mismatch probability for pairs of fingerprint signals within the specified parameter range in MRF. Specifically, the explicit ZZB is derived to establish a lower bound for the discrimination error in the fingerprint signal matching process within MRF. This bound illuminates the intrinsic limitations of MRF sequences, thereby fostering a deeper understanding of existing sequence performance. Subsequently, an optimal experiment design problem based on ZZB was formulated to ascertain the optimal scheme of acquisition parameters, maximizing discrimination power of MRF between different tissue types. Preliminary numerical experiments show that the optimized ZZB scheme outperforms both the conventional and CRB schemes in terms of the reconstruction accuracy of multiple parameter maps.

MR Optimized Reconstruction of Simultaneous Multi-Slice Imaging Using Diffusion Model

Diffusion model has been successfully applied to MRI reconstruction, including single and multi-coil acquisition of MRI data. Simultaneous multi-slice imaging (SMS), as a method for accelerating MR acquisition, can significantly reduce scanning time, but further optimization of reconstruction results is still possible. In order to optimize the reconstruction of SMS, we proposed a method to use diffusion model based on slice-GRAPPA and SPIRiT method. approach: Specifically, our method characterizes the prior distribution of SMS data by score matching and characterizes the k-space redundant prior between coils and slices based on self-consistency. With the utilization of diffusion model, we achieved better reconstruction results.The application of diffusion model can further reduce the scanning time of MRI without compromising image quality, making it more advantageous for clinical application

Joint PET-MRI Reconstruction with Diffusion Stochastic Differential Model

PET suffers from a low signal-to-noise ratio. Meanwhile, the k-space data acquisition process in MRI is time-consuming by PET-MRI systems. We aim to accelerate MRI and improve PET image quality. This paper proposed a novel joint reconstruction model by diffusion stochastic differential equations based on learning the joint probability distribution of PET and MRI. Compare the results underscore the qualitative and quantitative improvements our model brings to PET and MRI reconstruction, surpassing the current state-of-the-art methodologies. Joint PET-MRI reconstruction is a challenge in the PET-MRI system. This studies focused on the relationship extends beyond edges. In this study, PET is generated from MRI by learning joint probability distribution as the relationship.

COMAE: COMprehensive Attribute Exploration for Zero-shot Hashing

Zero-shot hashing (ZSH) has shown excellent success owing to its efficiency and generalization in large-scale retrieval scenarios. While considerable success has been achieved, there still exist urgent limitations. Existing works ignore the locality relationships of representations and attributes, which have effective transferability between seeable classes and unseeable classes. Also, the continuous-value attributes are not fully harnessed. In response, we conduct a COMprehensive Attribute Exploration for ZSH, named COMAE, which depicts the relationships from seen classes to unseen ones through three meticulously designed explorations, i.e., point-wise, pair-wise and class-wise consistency constraints. By regressing attributes from the proposed attribute prototype network, COMAE learns the local features that are relevant to the visual attributes. Then COMAE utilizes contrastive learning to comprehensively depict the context of attributes, rather than instance-independent optimization. Finally, the class-wise constraint is designed to cohesively learn the hash code, image representation, and visual attributes more effectively. Experimental results on the popular ZSH datasets demonstrate that COMAE outperforms state-of-the-art hashing techniques, especially in scenarios with a larger number of unseen label classes.

Joint Diffusion: Mutual Consistency-Driven Diffusion Model for PET-MRI Co-Reconstruction

Positron Emission Tomography and Magnetic Resonance Imaging (PET-MRI) systems can obtain functional and anatomical scans. PET suffers from a low signal-to-noise ratio. Meanwhile, the k-space data acquisition process in MRI is time-consuming. The study aims to accelerate MRI and enhance PET image quality. Conventional approaches involve the separate reconstruction of each modality within PET-MRI systems. However, there exists complementary information among multi-modal images. The complementary information can contribute to image reconstruction. In this study, we propose a novel PET-MRI joint reconstruction model employing a mutual consistency-driven diffusion mode, namely MC-Diffusion. MC-Diffusion learns the joint probability distribution of PET and MRI for utilizing complementary information. We conducted a series of contrast experiments about LPLS, Joint ISAT-net and MC-Diffusion by the ADNI dataset. The results underscore the qualitative and quantitative improvements achieved by MC-Diffusion, surpassing the state-of-the-art method.

Score-based Diffusion Models With Self-supervised Learning For Accelerated 3D Multi-contrast Cardiac Magnetic Resonance Imaging

Long scan time significantly hinders the widespread applications of three-dimensional multi-contrast cardiac magnetic resonance (3D-MC-CMR) imaging. This study aims to accelerate 3D-MC-CMR acquisition by a novel method based on score-based diffusion models with self-supervised learning. Specifically, we first establish a mapping between the undersampled k-space measurements and the MR images, utilizing a self-supervised Bayesian reconstruction network. Secondly, we develop a joint score-based diffusion model on 3D-MC-CMR images to capture their inherent distribution. The 3D-MC-CMR images are finally reconstructed using the conditioned Langenvin Markov chain Monte Carlo sampling. This approach enables accurate reconstruction without fully sampled training data. Its performance was tested on the dataset acquired by a 3D joint myocardial T1 and T1rho mapping sequence. The T1 and T1rho maps were estimated via a dictionary matching method from the reconstructed images. Experimental results show that the proposed method outperforms traditional compressed sensing and existing self-supervised deep learning MRI reconstruction methods. It also achieves high quality T1 and T1rho parametric maps close to the reference maps obtained by traditional mapping sequences, even at a high acceleration rate of 14.

Physics-Informed DeepMRI: Bridging the Gap from Heat Diffusion to k-Space Interpolation

In the field of parallel imaging (PI), alongside image-domain regularization methods, substantial research has been dedicated to exploring $k$-space interpolation. However, the interpretability of these methods remains an unresolved issue. Furthermore, these approaches currently face acceleration limitations that are comparable to those experienced by image-domain methods. In order to enhance interpretability and overcome the acceleration limitations, this paper introduces an interpretable framework that unifies both $k$-space interpolation techniques and image-domain methods, grounded in the physical principles of heat diffusion equations. Building upon this foundational framework, a novel $k$-space interpolation method is proposed. Specifically, we model the process of high-frequency information attenuation in $k$-space as a heat diffusion equation, while the effort to reconstruct high-frequency information from low-frequency regions can be conceptualized as a reverse heat equation. However, solving the reverse heat equation poses a challenging inverse problem. To tackle this challenge, we modify the heat equation to align with the principles of magnetic resonance PI physics and employ the score-based generative method to precisely execute the modified reverse heat diffusion. Finally, experimental validation conducted on publicly available datasets demonstrates the superiority of the proposed approach over traditional $k$-space interpolation methods, deep learning-based $k$-space interpolation methods, and conventional diffusion models in terms of reconstruction accuracy, particularly in high-frequency regions.

Synthesizing PET images from High-field and Ultra-high-field MR images Using Joint Diffusion Attention Model

MRI and PET are crucial diagnostic tools for brain diseases, as they provide complementary information on brain structure and function. However, PET scanning is costly and involves radioactive exposure, resulting in a lack of PET. Moreover, simultaneous PET and MRI at ultra-high-field are currently hardly infeasible. Ultra-high-field imaging has unquestionably proven valuable in both clinical and academic settings, especially in the field of cognitive neuroimaging. These motivate us to propose a method for synthetic PET from high-filed MRI and ultra-high-field MRI. From a statistical perspective, the joint probability distribution (JPD) is the most direct and fundamental means of portraying the correlation between PET and MRI. This paper proposes a novel joint diffusion attention model which has the joint probability distribution and attention strategy, named JDAM. JDAM has a diffusion process and a sampling process. The diffusion process involves the gradual diffusion of PET to Gaussian noise by adding Gaussian noise, while MRI remains fixed. JPD of MRI and noise-added PET was learned in the diffusion process. The sampling process is a predictor-corrector. PET images were generated from MRI by JPD of MRI and noise-added PET. The predictor is a reverse diffusion process and the corrector is Langevin dynamics. Experimental results on the public Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset demonstrate that the proposed method outperforms state-of-the-art CycleGAN for high-field MRI (3T MRI). Finally, synthetic PET images from the ultra-high-field (5T MRI and 7T MRI) be attempted, providing a possibility for ultra-high-field PET-MRI imaging.