MedImageInsight: An Open-Source Embedding Model for General Domain Medical Imaging

In this work, we present MedImageInsight, an open-source medical imaging embedding model. MedImageInsight is trained on medical images with associated text and labels across a diverse collection of domains, including X-Ray, CT, MRI, dermoscopy, OCT, fundus photography, ultrasound, histopathology, and mammography. Rigorous evaluations demonstrate MedImageInsight's ability to achieve state-of-the-art (SOTA) or human expert level performance across classification, image-image search, and fine-tuning tasks. Specifically, on public datasets, MedImageInsight achieves SOTA in CT 3D medical image retrieval, as well as SOTA in disease classification and search for chest X-ray, dermatology, and OCT imaging. Furthermore, MedImageInsight achieves human expert performance in bone age estimation (on both public and partner data), as well as AUC above 0.9 in most other domains. When paired with a text decoder, MedImageInsight achieves near SOTA level single image report findings generation with less than 10\% the parameters of other models. Compared to fine-tuning GPT-4o with only MIMIC-CXR data for the same task, MedImageInsight outperforms in clinical metrics, but underperforms on lexical metrics where GPT-4o sets a new SOTA. Importantly for regulatory purposes, MedImageInsight can generate ROC curves, adjust sensitivity and specificity based on clinical need, and provide evidence-based decision support through image-image search (which can also enable retrieval augmented generation). In an independent clinical evaluation of image-image search in chest X-ray, MedImageInsight outperformed every other publicly available foundation model evaluated by large margins (over 6 points AUC), and significantly outperformed other models in terms of AI fairness (across age and gender). We hope releasing MedImageInsight will help enhance collective progress in medical imaging AI research and development.

Push and Pull: A Framework for Measuring Attentional Agency

We propose a framework for measuring attentional agency - the ability to allocate one's attention according to personal desires, goals, and intentions - on digital platforms. Platforms extend people's limited powers of attention by extrapolating their preferences to large collections of previously unconsidered informational objects. However, platforms typically also allow people to influence one another's attention. We introduce a formal framework for measuring how much a given platform empowers people to both pull information into their own attentional field and push information into the attentional fields of others. We also use these definitions to shed light on the implications of generative foundation models, which enable users to bypass the implicit "attentional bargain" that underlies embedded advertising and other methods for capturing economic value from informational goods. We conclude with a set of policy strategies that can be used to understand and reshape the distribution of attentional agency online.

Verifiable evaluations of machine learning models using zkSNARKs

In a world of increasing closed-source commercial machine learning models, model evaluations from developers must be taken at face value. These benchmark results, whether over task accuracy, bias evaluations, or safety checks, are traditionally impossible to verify by a model end-user without the costly or impossible process of re-performing the benchmark on black-box model outputs. This work presents a method of verifiable model evaluation using model inference through zkSNARKs. The resulting zero-knowledge computational proofs of model outputs over datasets can be packaged into verifiable evaluation attestations showing that models with fixed private weights achieve stated performance or fairness metrics over public inputs. These verifiable attestations can be performed on any standard neural network model with varying compute requirements. For the first time, we demonstrate this across a sample of real-world models and highlight key challenges and design solutions. This presents a new transparency paradigm in the verifiable evaluation of private models.

Contextual Confidence and Generative AI

Generative AI models perturb the foundations of effective human communication. They present new challenges to contextual confidence, disrupting participants' ability to identify the authentic context of communication and their ability to protect communication from reuse and recombination outside its intended context. In this paper, we describe strategies--tools, technologies and policies--that aim to stabilize communication in the face of these challenges. The strategies we discuss fall into two broad categories. Containment strategies aim to reassert context in environments where it is currently threatened--a reaction to the context-free expectations and norms established by the internet. Mobilization strategies, by contrast, view the rise of generative AI as an opportunity to proactively set new and higher expectations around privacy and authenticity in mediated communication.

Unsupervised Learning of Molecular Embeddings for Enhanced Clustering and Emergent Properties for Chemical Compounds

The detailed analysis of molecular structures and properties holds great potential for drug development discovery through machine learning. Developing an emergent property in the model to understand molecules would broaden the horizons for development with a new computational tool. We introduce various methods to detect and cluster chemical compounds based on their SMILES data. Our first method, analyzing the graphical structures of chemical compounds using embedding data, employs vector search to meet our threshold value. The results yielded pronounced, concentrated clusters, and the method produced favorable results in querying and understanding the compounds. We also used natural language description embeddings stored in a vector database with GPT3.5, which outperforms the base model. Thus, we introduce a similarity search and clustering algorithm to aid in searching for and interacting with molecules, enhancing efficiency in chemical exploration and enabling future development of emergent properties in molecular property prediction models.

Face Recognition in the age of CLIP & Billion image datasets

CLIP (Contrastive Language-Image Pre-training) models developed by OpenAI have achieved outstanding results on various image recognition and retrieval tasks, displaying strong zero-shot performance. This means that they are able to perform effectively on tasks for which they have not been explicitly trained. Inspired by the success of OpenAI CLIP, a new publicly available dataset called LAION-5B was collected which resulted in the development of open ViT-H/14, ViT-G/14 models that outperform the OpenAI L/14 model. The LAION-5B dataset also released an approximate nearest neighbor index, with a web interface for search & subset creation. In this paper, we evaluate the performance of various CLIP models as zero-shot face recognizers. Our findings show that CLIP models perform well on face recognition tasks, but increasing the size of the CLIP model does not necessarily lead to improved accuracy. Additionally, we investigate the robustness of CLIP models against data poisoning attacks by testing their performance on poisoned data. Through this analysis, we aim to understand the potential consequences and misuse of search engines built using CLIP models, which could potentially function as unintentional face recognition engines.

NFT Appraisal Prediction: Utilizing Search Trends, Public Market Data, Linear Regression and Recurrent Neural Networks

In this paper we investigate the correlation between NFT valuations and various features from three primary categories: public market data, NFT metadata, and social trends data.