Political-LLM: Large Language Models in Political Science

In recent years, large language models (LLMs) have been widely adopted in political science tasks such as election prediction, sentiment analysis, policy impact assessment, and misinformation detection. Meanwhile, the need to systematically understand how LLMs can further revolutionize the field also becomes urgent. In this work, we--a multidisciplinary team of researchers spanning computer science and political science--present the first principled framework termed Political-LLM to advance the comprehensive understanding of integrating LLMs into computational political science. Specifically, we first introduce a fundamental taxonomy classifying the existing explorations into two perspectives: political science and computational methodologies. In particular, from the political science perspective, we highlight the role of LLMs in automating predictive and generative tasks, simulating behavior dynamics, and improving causal inference through tools like counterfactual generation; from a computational perspective, we introduce advancements in data preparation, fine-tuning, and evaluation methods for LLMs that are tailored to political contexts. We identify key challenges and future directions, emphasizing the development of domain-specific datasets, addressing issues of bias and fairness, incorporating human expertise, and redefining evaluation criteria to align with the unique requirements of computational political science. Political-LLM seeks to serve as a guidebook for researchers to foster an informed, ethical, and impactful use of Artificial Intelligence in political science. Our online resource is available at: http://political-llm.org/.

DrugAgent: Automating AI-aided Drug Discovery Programming through LLM Multi-Agent Collaboration

Recent advancements in Large Language Models (LLMs) have opened new avenues for accelerating drug discovery processes. Despite their potential, several critical challenges remain unsolved, particularly in translating theoretical ideas into practical applications within the highly specialized field of pharmaceutical research, limiting practitioners from leveraging the latest AI development in drug discovery. To this end, we introduce DrugAgent, a multi-agent framework aimed at automating machine learning (ML) programming in drug discovery. DrugAgent incorporates domain expertise by identifying specific requirements and building domain-specific tools, while systematically exploring different ideas to find effective solutions. A preliminary case study demonstrates DrugAgent's potential to overcome key limitations LLMs face in drug discovery, moving toward AI-driven innovation. For example, DrugAgent is able to complete the ML programming pipeline end-to-end, from data acquisition to performance evaluation for the ADMET prediction task, and finally select the best model, where the random forest model achieves an F1 score of 0.92 when predicting absorption using the PAMPA dataset.

Does Differential Privacy Impact Bias in Pretrained NLP Models?

Differential privacy (DP) is applied when fine-tuning pre-trained large language models (LLMs) to limit leakage of training examples. While most DP research has focused on improving a model's privacy-utility tradeoff, some find that DP can be unfair to or biased against underrepresented groups. In this work, we show the impact of DP on bias in LLMs through empirical analysis. Differentially private training can increase the model bias against protected groups w.r.t AUC-based bias metrics. DP makes it more difficult for the model to differentiate between the positive and negative examples from the protected groups and other groups in the rest of the population. Our results also show that the impact of DP on bias is not only affected by the privacy protection level but also the underlying distribution of the dataset.

MUSE: Machine Unlearning Six-Way Evaluation for Language Models

Language models (LMs) are trained on vast amounts of text data, which may include private and copyrighted content. Data owners may request the removal of their data from a trained model due to privacy or copyright concerns. However, exactly unlearning only these datapoints (i.e., retraining with the data removed) is intractable in modern-day models. This has led to the development of many approximate unlearning algorithms. The evaluation of the efficacy of these algorithms has traditionally been narrow in scope, failing to precisely quantify the success and practicality of the algorithm from the perspectives of both the model deployers and the data owners. We address this issue by proposing MUSE, a comprehensive machine unlearning evaluation benchmark that enumerates six diverse desirable properties for unlearned models: (1) no verbatim memorization, (2) no knowledge memorization, (3) no privacy leakage, (4) utility preservation on data not intended for removal, (5) scalability with respect to the size of removal requests, and (6) sustainability over sequential unlearning requests. Using these criteria, we benchmark how effectively eight popular unlearning algorithms on 7B-parameter LMs can unlearn Harry Potter books and news articles. Our results demonstrate that most algorithms can prevent verbatim memorization and knowledge memorization to varying degrees, but only one algorithm does not lead to severe privacy leakage. Furthermore, existing algorithms fail to meet deployer's expectations because they often degrade general model utility and also cannot sustainably accommodate successive unlearning requests or large-scale content removal. Our findings identify key issues with the practicality of existing unlearning algorithms on language models, and we release our benchmark to facilitate further evaluations: muse-bench.github.io

CLIMB: A Benchmark of Clinical Bias in Large Language Models

Large language models (LLMs) are increasingly applied to clinical decision-making. However, their potential to exhibit bias poses significant risks to clinical equity. Currently, there is a lack of benchmarks that systematically evaluate such clinical bias in LLMs. While in downstream tasks, some biases of LLMs can be avoided such as by instructing the model to answer "I'm not sure...", the internal bias hidden within the model still lacks deep studies. We introduce CLIMB (shorthand for A Benchmark of Clinical Bias in Large Language Models), a pioneering comprehensive benchmark to evaluate both intrinsic (within LLMs) and extrinsic (on downstream tasks) bias in LLMs for clinical decision tasks. Notably, for intrinsic bias, we introduce a novel metric, AssocMAD, to assess the disparities of LLMs across multiple demographic groups. Additionally, we leverage counterfactual intervention to evaluate extrinsic bias in a task of clinical diagnosis prediction. Our experiments across popular and medically adapted LLMs, particularly from the Mistral and LLaMA families, unveil prevalent behaviors with both intrinsic and extrinsic bias. This work underscores the critical need to mitigate clinical bias and sets a new standard for future evaluations of LLMs' clinical bias.

Images Speak Louder than Words: Understanding and Mitigating Bias in Vision-Language Model from a Causal Mediation Perspective

Vision-language models (VLMs) pre-trained on extensive datasets can inadvertently learn biases by correlating gender information with specific objects or scenarios. Current methods, which focus on modifying inputs and monitoring changes in the model's output probability scores, often struggle to comprehensively understand bias from the perspective of model components. We propose a framework that incorporates causal mediation analysis to measure and map the pathways of bias generation and propagation within VLMs. This approach allows us to identify the direct effects of interventions on model bias and the indirect effects of interventions on bias mediated through different model components. Our results show that image features are the primary contributors to bias, with significantly higher impacts than text features, specifically accounting for 32.57% and 12.63% of the bias in the MSCOCO and PASCAL-SENTENCE datasets, respectively. Notably, the image encoder's contribution surpasses that of the text encoder and the deep fusion encoder. Further experimentation confirms that contributions from both language and vision modalities are aligned and non-conflicting. Consequently, focusing on blurring gender representations within the image encoder, which contributes most to the model bias, reduces bias efficiently by 22.03% and 9.04% in the MSCOCO and PASCAL-SENTENCE datasets, respectively, with minimal performance loss or increased computational demands.

Rethinking LLM-based Preference Evaluation

Recently, large language model (LLM)-based preference evaluation has been widely adopted to compare pairs of model responses. However, a severe bias towards lengthy responses has been observed, raising concerns about the reliability of this evaluation method. In this work, we designed a series of controlled experiments to study the major impacting factors of the metric of LLM-based preference evaluation, i.e., win rate, and conclude that the win rate is affected by two axes of model response: desirability and information mass, where the former is length-independent and related to trustworthiness, and the latter is length-dependent and can be represented by conditional entropy. We find that length impacts the existing evaluations by influencing information mass. However, a reliable evaluation metric should not only assess content quality but also ensure that the assessment is not confounded by extraneous factors such as response length. Therefore, we propose a simple yet effective adjustment, AdapAlpaca, to the existing practice of win rate measurement. Specifically, by adjusting the lengths of reference answers to match the test model's answers within the same interval, we debias information mass relative to length, ensuring a fair model evaluation.

InterIntent: Investigating Social Intelligence of LLMs via Intention Understanding in an Interactive Game Context

Large language models (LLMs) have demonstrated the potential to mimic human social intelligence. However, most studies focus on simplistic and static self-report or performance-based tests, which limits the depth and validity of the analysis. In this paper, we developed a novel framework, InterIntent, to assess LLMs' social intelligence by mapping their ability to understand and manage intentions in a game setting. We focus on four dimensions of social intelligence: situational awareness, self-regulation, self-awareness, and theory of mind. Each dimension is linked to a specific game task: intention selection, intention following, intention summarization, and intention guessing. Our findings indicate that while LLMs exhibit high proficiency in selecting intentions, achieving an accuracy of 88\%, their ability to infer the intentions of others is significantly weaker, trailing human performance by 20\%. Additionally, game performance correlates with intention understanding, highlighting the importance of the four components towards success in this game. These findings underline the crucial role of intention understanding in evaluating LLMs' social intelligence and highlight the potential of using social deduction games as a complex testbed to enhance LLM evaluation. InterIntent contributes a structured approach to bridging the evaluation gap in social intelligence within multiplayer games.

"You Gotta be a Doctor, Lin": An Investigation of Name-Based Bias of Large Language Models in Employment Recommendations

Social science research has shown that candidates with names indicative of certain races or genders often face discrimination in employment practices. Similarly, Large Language Models (LLMs) have demonstrated racial and gender biases in various applications. In this study, we utilize GPT-3.5-Turbo and Llama 3-70B-Instruct to simulate hiring decisions and salary recommendations for candidates with 320 first names that strongly signal their race and gender, across over 750,000 prompts. Our empirical results indicate a preference among these models for hiring candidates with White female-sounding names over other demographic groups across 40 occupations. Additionally, even among candidates with identical qualifications, salary recommendations vary by as much as 5% between different subgroups. A comparison with real-world labor data reveals inconsistent alignment with U.S. labor market characteristics, underscoring the necessity of risk investigation of LLM-powered systems.

TrustLLM: Trustworthiness in Large Language Models

Large language models (LLMs), exemplified by ChatGPT, have gained considerable attention for their excellent natural language processing capabilities. Nonetheless, these LLMs present many challenges, particularly in the realm of trustworthiness. Therefore, ensuring the trustworthiness of LLMs emerges as an important topic. This paper introduces TrustLLM, a comprehensive study of trustworthiness in LLMs, including principles for different dimensions of trustworthiness, established benchmark, evaluation, and analysis of trustworthiness for mainstream LLMs, and discussion of open challenges and future directions. Specifically, we first propose a set of principles for trustworthy LLMs that span eight different dimensions. Based on these principles, we further establish a benchmark across six dimensions including truthfulness, safety, fairness, robustness, privacy, and machine ethics. We then present a study evaluating 16 mainstream LLMs in TrustLLM, consisting of over 30 datasets. Our findings firstly show that in general trustworthiness and utility (i.e., functional effectiveness) are positively related. Secondly, our observations reveal that proprietary LLMs generally outperform most open-source counterparts in terms of trustworthiness, raising concerns about the potential risks of widely accessible open-source LLMs. However, a few open-source LLMs come very close to proprietary ones. Thirdly, it is important to note that some LLMs may be overly calibrated towards exhibiting trustworthiness, to the extent that they compromise their utility by mistakenly treating benign prompts as harmful and consequently not responding. Finally, we emphasize the importance of ensuring transparency not only in the models themselves but also in the technologies that underpin trustworthiness. Knowing the specific trustworthy technologies that have been employed is crucial for analyzing their effectiveness.