A graph neural network-based multispectral-view learning model for diabetic macular ischemia detection from color fundus photographs

Diabetic macular ischemia (DMI), marked by the loss of retinal capillaries in the macular area, contributes to vision impairment in patients with diabetes. Although color fundus photographs (CFPs), combined with artificial intelligence (AI), have been extensively applied in detecting various eye diseases, including diabetic retinopathy (DR), their applications in detecting DMI remain unexplored, partly due to skepticism among ophthalmologists regarding its feasibility. In this study, we propose a graph neural network-based multispectral view learning (GNN-MSVL) model designed to detect DMI from CFPs. The model leverages higher spectral resolution to capture subtle changes in fundus reflectance caused by ischemic tissue, enhancing sensitivity to DMI-related features. The proposed approach begins with computational multispectral imaging (CMI) to reconstruct 24-wavelength multispectral fundus images from CFPs. ResNeXt101 is employed as the backbone for multi-view learning to extract features from the reconstructed images. Additionally, a GNN with a customized jumper connection strategy is designed to enhance cross-spectral relationships, facilitating comprehensive and efficient multispectral view learning. The study included a total of 1,078 macula-centered CFPs from 1,078 eyes of 592 patients with diabetes, of which 530 CFPs from 530 eyes of 300 patients were diagnosed with DMI. The model achieved an accuracy of 84.7 percent and an area under the receiver operating characteristic curve (AUROC) of 0.900 (95 percent CI: 0.852-0.937) on eye-level, outperforming both the baseline model trained from CFPs and human experts (p-values less than 0.01). These findings suggest that AI-based CFP analysis holds promise for detecting DMI, contributing to its early and low-cost screening.

Q-PETR: Quant-aware Position Embedding Transformation for Multi-View 3D Object Detection

PETR-based methods have dominated benchmarks in 3D perception and are increasingly becoming a key component in modern autonomous driving systems. However, their quantization performance significantly degrades when INT8 inference is required, with a degradation of 58.2% in mAP and 36.9% in NDS on the NuScenes dataset. To address this issue, we propose a quantization-aware position embedding transformation for multi-view 3D object detection, termed Q-PETR. Q-PETR offers a quantizationfriendly and deployment-friendly architecture while preserving the original performance of PETR. It substantially narrows the accuracy gap between INT8 and FP32 inference for PETR-series methods. Without bells and whistles, our approach reduces the mAP and NDS drop to within 1% under standard 8-bit per-tensor post-training quantization. Furthermore, our method exceeds the performance of the original PETR in terms of floating-point precision. Extensive experiments across a variety of PETR-series models demonstrate its broad generalization.

NVR: Vector Runahead on NPUs for Sparse Memory Access

Deep Neural Networks are increasingly leveraging sparsity to reduce the scaling up of model parameter size. However, reducing wall-clock time through sparsity and pruning remains challenging due to irregular memory access patterns, leading to frequent cache misses. In this paper, we present NPU Vector Runahead (NVR), a prefetching mechanism tailored for NPUs to address cache miss problems in sparse DNN workloads. Rather than optimising memory patterns with high overhead and poor portability, NVR adapts runahead execution to the unique architecture of NPUs. NVR provides a general micro-architectural solution for sparse DNN workloads without requiring compiler or algorithmic support, operating as a decoupled, speculative, lightweight hardware sub-thread alongside the NPU, with minimal hardware overhead (under 5%). NVR achieves an average 90% reduction in cache misses compared to SOTA prefetching in general-purpose processors, delivering 4x average speedup on sparse workloads versus NPUs without prefetching. Moreover, we investigate the advantages of incorporating a small cache (16KB) into the NPU combined with NVR. Our evaluation shows that expanding this modest cache delivers 5x higher performance benefits than increasing the L2 cache size by the same amount.

GSQ-Tuning: Group-Shared Exponents Integer in Fully Quantized Training for LLMs On-Device Fine-tuning

Large Language Models (LLMs) fine-tuning technologies have achieved remarkable results. However, traditional LLM fine-tuning approaches face significant challenges: they require large Floating Point (FP) computation, raising privacy concerns when handling sensitive data, and are impractical for resource-constrained edge devices. While Parameter-Efficient Fine-Tuning (PEFT) techniques reduce trainable parameters, their reliance on floating-point arithmetic creates fundamental incompatibilities with edge hardware. In this work, we introduce a novel framework for on-device LLM fine-tuning that eliminates the need for floating-point operations in both inference and training, named GSQ-Tuning. At its core is the Group-Shared Exponents Integer format, which efficiently represents model parameters in integer format using shared exponents among parameter groups. When combined with LoRA-like adapters, this enables fully integer-based fine-tuning that is both memory and compute efficient. We demonstrate that our approach achieves accuracy comparable to FP16-based fine-tuning while significantly reducing memory usage (50%). Moreover, compared to FP8, our method can reduce 5x power consumption and 11x chip area with same performance, making large-scale model adaptation feasible on edge devices.

Is an Ultra Large Natural Image-Based Foundation Model Superior to a Retina-Specific Model for Detecting Ocular and Systemic Diseases?

The advent of foundation models (FMs) is transforming medical domain. In ophthalmology, RETFound, a retina-specific FM pre-trained sequentially on 1.4 million natural images and 1.6 million retinal images, has demonstrated high adaptability across clinical applications. Conversely, DINOv2, a general-purpose vision FM pre-trained on 142 million natural images, has shown promise in non-medical domains. However, its applicability to clinical tasks remains underexplored. To address this, we conducted head-to-head evaluations by fine-tuning RETFound and three DINOv2 models (large, base, small) for ocular disease detection and systemic disease prediction tasks, across eight standardized open-source ocular datasets, as well as the Moorfields AlzEye and the UK Biobank datasets. DINOv2-large model outperformed RETFound in detecting diabetic retinopathy (AUROC=0.850-0.952 vs 0.823-0.944, across three datasets, all P<=0.007) and multi-class eye diseases (AUROC=0.892 vs. 0.846, P<0.001). In glaucoma, DINOv2-base model outperformed RETFound (AUROC=0.958 vs 0.940, P<0.001). Conversely, RETFound achieved superior performance over all DINOv2 models in predicting heart failure, myocardial infarction, and ischaemic stroke (AUROC=0.732-0.796 vs 0.663-0.771, all P<0.001). These trends persisted even with 10% of the fine-tuning data. These findings showcase the distinct scenarios where general-purpose and domain-specific FMs excel, highlighting the importance of aligning FM selection with task-specific requirements to optimise clinical performance.

GSRender: Deduplicated Occupancy Prediction via Weakly Supervised 3D Gaussian Splatting

3D occupancy perception is gaining increasing attention due to its capability to offer detailed and precise environment representations. Previous weakly-supervised NeRF methods balance efficiency and accuracy, with mIoU varying by 5-10 points due to sampling count along camera rays. Recently, real-time Gaussian splatting has gained widespread popularity in 3D reconstruction, and the occupancy prediction task can also be viewed as a reconstruction task. Consequently, we propose GSRender, which naturally employs 3D Gaussian Splatting for occupancy prediction, simplifying the sampling process. In addition, the limitations of 2D supervision result in duplicate predictions along the same camera ray. We implemented the Ray Compensation (RC) module, which mitigates this issue by compensating for features from adjacent frames. Finally, we redesigned the loss to eliminate the impact of dynamic objects from adjacent frames. Extensive experiments demonstrate that our approach achieves SOTA (state-of-the-art) results in RayIoU (+6.0), while narrowing the gap with 3D supervision methods. Our code will be released soon.

Panoptic-FlashOcc: An Efficient Baseline to Marry Semantic Occupancy with Panoptic via Instance Center

Panoptic occupancy poses a novel challenge by aiming to integrate instance occupancy and semantic occupancy within a unified framework. However, there is still a lack of efficient solutions for panoptic occupancy. In this paper, we propose Panoptic-FlashOcc, a straightforward yet robust 2D feature framework that enables realtime panoptic occupancy. Building upon the lightweight design of FlashOcc, our approach simultaneously learns semantic occupancy and class-aware instance clustering in a single network, these outputs are jointly incorporated through panoptic occupancy procession for panoptic occupancy. This approach effectively addresses the drawbacks of high memory and computation requirements associated with three-dimensional voxel-level representations. With its straightforward and efficient design that facilitates easy deployment, Panoptic-FlashOcc demonstrates remarkable achievements in panoptic occupancy prediction. On the Occ3D-nuScenes benchmark, it achieves exceptional performance, with 38.5 RayIoU and 29.1 mIoU for semantic occupancy, operating at a rapid speed of 43.9 FPS. Furthermore, it attains a notable score of 16.0 RayPQ for panoptic occupancy, accompanied by a fast inference speed of 30.2 FPS. These results surpass the performance of existing methodologies in terms of both speed and accuracy. The source code and trained models can be found at the following github repository: https://github.com/Yzichen/FlashOCC.

M&M VTO: Multi-Garment Virtual Try-On and Editing

We present M&M VTO, a mix and match virtual try-on method that takes as input multiple garment images, text description for garment layout and an image of a person. An example input includes: an image of a shirt, an image of a pair of pants, "rolled sleeves, shirt tucked in", and an image of a person. The output is a visualization of how those garments (in the desired layout) would look like on the given person. Key contributions of our method are: 1) a single stage diffusion based model, with no super resolution cascading, that allows to mix and match multiple garments at 1024x512 resolution preserving and warping intricate garment details, 2) architecture design (VTO UNet Diffusion Transformer) to disentangle denoising from person specific features, allowing for a highly effective finetuning strategy for identity preservation (6MB model per individual vs 4GB achieved with, e.g., dreambooth finetuning); solving a common identity loss problem in current virtual try-on methods, 3) layout control for multiple garments via text inputs specifically finetuned over PaLI-3 for virtual try-on task. Experimental results indicate that M&M VTO achieves state-of-the-art performance both qualitatively and quantitatively, as well as opens up new opportunities for virtual try-on via language-guided and multi-garment try-on.

PillarHist: A Quantization-aware Pillar Feature Encoder based on Height-aware Histogram

Real-time and high-performance 3D object detection plays a critical role in autonomous driving and robotics. Recent pillar-based 3D object detectors have gained significant attention due to their compact representation and low computational overhead, making them suitable for onboard deployment and quantization. However, existing pillar-based detectors still suffer from information loss along height dimension and large numerical distribution difference during pillar feature encoding (PFE), which severely limits their performance and quantization potential. To address above issue, we first unveil the importance of different input information during PFE and identify the height dimension as a key factor in enhancing 3D detection performance. Motivated by this observation, we propose a height-aware pillar feature encoder named PillarHist. Specifically, PillarHist statistics the discrete distribution of points at different heights within one pillar. This simple yet effective design greatly preserves the information along the height dimension while significantly reducing the computation overhead of the PFE. Meanwhile, PillarHist also constrains the arithmetic distribution of PFE input to a stable range, making it quantization-friendly. Notably, PillarHist operates exclusively within the PFE stage to enhance performance, enabling seamless integration into existing pillar-based methods without introducing complex operations. Extensive experiments show the effectiveness of PillarHist in terms of both efficiency and performance.

I-LLM: Efficient Integer-Only Inference for Fully-Quantized Low-Bit Large Language Models

Post-training quantization (PTQ) serves as a potent technique to accelerate the inference of large language models (LLMs). Nonetheless, existing works still necessitate a considerable number of floating-point (FP) operations during inference, including additional quantization and de-quantization, as well as non-linear operators such as RMSNorm and Softmax. This limitation hinders the deployment of LLMs on the edge and cloud devices. In this paper, we identify the primary obstacle to integer-only quantization for LLMs lies in the large fluctuation of activations across channels and tokens in both linear and non-linear operations. To address this issue, we propose I-LLM, a novel integer-only fully-quantized PTQ framework tailored for LLMs. Specifically, (1) we develop Fully-Smooth Block-Reconstruction (FSBR) to aggressively smooth inter-channel variations of all activations and weights. (2) to alleviate degradation caused by inter-token variations, we introduce a novel approach called Dynamic Integer-only MatMul (DI-MatMul). This method enables dynamic quantization in full-integer matrix multiplication by dynamically quantizing the input and outputs with integer-only operations. (3) we design DI-ClippedSoftmax, DI-Exp, and DI-Normalization, which utilize bit shift to execute non-linear operators efficiently while maintaining accuracy. The experiment shows that our I-LLM achieves comparable accuracy to the FP baseline and outperforms non-integer quantization methods. For example, I-LLM can operate at W4A4 with negligible loss of accuracy. To our knowledge, we are the first to bridge the gap between integer-only quantization and LLMs. We've published our code on anonymous.4open.science, aiming to contribute to the advancement of this field.