Abstract:While Chain-of-Thought (CoT) prompting advances LLM reasoning, challenges persist in consistency, accuracy, and self-correction, especially for complex or ethically sensitive tasks. Existing single-dimensional reflection methods offer insufficient improvements. We propose MyGO Poly-Reflective Chain-of-Thought (PR-CoT), a novel methodology employing structured multi-perspective reflection. After initial CoT, PR-CoT guides the LLM to self-assess its reasoning across multiple predefined angles: logical consistency, information completeness, biases/ethics, and alternative solutions. Implemented purely via prompt engineering, this process refines the initial CoT into a more robust and accurate final answer without model retraining. Experiments across arithmetic, commonsense, ethical decision-making, and logical puzzles, using GPT-three point five and GPT-four models, demonstrate PR-CoT's superior performance. It significantly outperforms traditional CoT and existing reflection methods in logical consistency and error correction, with notable gains in nuanced domains like ethical decision-making. Ablation studies, human evaluations, and qualitative analyses further validate the contribution of each reflection perspective and the overall efficacy of our poly-reflective paradigm in fostering more reliable LLM reasoning.
Abstract:Multimodal cardiovascular magnetic resonance (CMR) imaging provides comprehensive and non-invasive insights into cardiovascular disease (CVD) diagnosis and underlying mechanisms. Despite decades of advancements, its widespread clinical adoption remains constrained by prolonged scan times and heterogeneity across medical environments. This underscores the urgent need for a generalist reconstruction foundation model for ultra-fast CMR imaging, one capable of adapting across diverse imaging scenarios and serving as the essential substrate for all downstream analyses. To enable this goal, we curate MMCMR-427K, the largest and most comprehensive multimodal CMR k-space database to date, comprising 427,465 multi-coil k-space data paired with structured metadata across 13 international centers, 12 CMR modalities, 15 scanners, and 17 CVD categories in populations across three continents. Building on this unprecedented resource, we introduce CardioMM, a generalist reconstruction foundation model capable of dynamically adapting to heterogeneous fast CMR imaging scenarios. CardioMM unifies semantic contextual understanding with physics-informed data consistency to deliver robust reconstructions across varied scanners, protocols, and patient presentations. Comprehensive evaluations demonstrate that CardioMM achieves state-of-the-art performance in the internal centers and exhibits strong zero-shot generalization to unseen external settings. Even at imaging acceleration up to 24x, CardioMM reliably preserves key cardiac phenotypes, quantitative myocardial biomarkers, and diagnostic image quality, enabling a substantial increase in CMR examination throughput without compromising clinical integrity. Together, our open-access MMCMR-427K database and CardioMM framework establish a scalable pathway toward high-throughput, high-quality, and clinically accessible cardiovascular imaging.




Abstract:Background: Late Gadolinium Enhancement (LGE) imaging is the gold standard for assessing myocardial fibrosis and scarring, with left ventricular (LV) LGE extent predicting major adverse cardiac events (MACE). Despite its importance, routine LGE-based LV scar quantification is hindered by labor-intensive manual segmentation and inter-observer variability. Methods: We propose ScarNet, a hybrid model combining a transformer-based encoder from the Medical Segment Anything Model (MedSAM) with a convolution-based U-Net decoder, enhanced by tailored attention blocks. ScarNet was trained on 552 ischemic cardiomyopathy patients with expert segmentations of myocardial and scar boundaries and tested on 184 separate patients. Results: ScarNet achieved robust scar segmentation in 184 test patients, yielding a median Dice score of 0.912 (IQR: 0.863--0.944), significantly outperforming MedSAM (median Dice = 0.046, IQR: 0.043--0.047) and nnU-Net (median Dice = 0.638, IQR: 0.604--0.661). ScarNet demonstrated lower bias (-0.63%) and coefficient of variation (4.3%) compared to MedSAM (bias: -13.31%, CoV: 130.3%) and nnU-Net (bias: -2.46%, CoV: 20.3%). In Monte Carlo simulations with noise perturbations, ScarNet achieved significantly higher scar Dice (0.892 \pm 0.053, CoV = 5.9%) than MedSAM (0.048 \pm 0.112, CoV = 233.3%) and nnU-Net (0.615 \pm 0.537, CoV = 28.7%). Conclusion: ScarNet outperformed MedSAM and nnU-Net in accurately segmenting myocardial and scar boundaries in LGE images. The model exhibited robust performance across diverse image qualities and scar patterns.




Abstract:Finetuned large language models (LLMs) have shown remarkable performance in financial tasks, such as sentiment analysis and information retrieval. Due to privacy concerns, finetuning and deploying Financial LLMs (FinLLMs) locally are crucial for institutions. However, finetuning FinLLMs poses challenges including GPU memory constraints and long input sequences. In this paper, we employ quantized low-rank adaptation (QLoRA) to finetune FinLLMs, which leverage low-rank matrix decomposition and quantization techniques to significantly reduce computational requirements while maintaining high model performance. We also employ data and pipeline parallelism to enable local finetuning using cost-effective, widely accessible GPUs. Experiments on financial datasets demonstrate that our method achieves substantial improvements in accuracy, GPU memory usage, and time efficiency, underscoring the potential of lowrank methods for scalable and resource-efficient LLM finetuning.




Abstract:Unsupervised domain adaptation (UDA) is essential for medical image segmentation, especially in cross-modality data scenarios. UDA aims to transfer knowledge from a labeled source domain to an unlabeled target domain, thereby reducing the dependency on extensive manual annotations. This paper presents DRL-STNet, a novel framework for cross-modality medical image segmentation that leverages generative adversarial networks (GANs), disentangled representation learning (DRL), and self-training (ST). Our method leverages DRL within a GAN to translate images from the source to the target modality. Then, the segmentation model is initially trained with these translated images and corresponding source labels and then fine-tuned iteratively using a combination of synthetic and real images with pseudo-labels and real labels. The proposed framework exhibits superior performance in abdominal organ segmentation on the FLARE challenge dataset, surpassing state-of-the-art methods by 11.4% in the Dice similarity coefficient and by 13.1% in the Normalized Surface Dice metric, achieving scores of 74.21% and 80.69%, respectively. The average running time is 41 seconds, and the area under the GPU memory-time curve is 11,292 MB. These results indicate the potential of DRL-STNet for enhancing cross-modality medical image segmentation tasks.




Abstract:Large language models (LLMs) have advanced financial applications, yet they often lack sufficient financial knowledge and struggle with tasks involving multi-modal inputs like tables and time series data. To address these limitations, we introduce \textit{Open-FinLLMs}, a series of Financial LLMs. We begin with FinLLaMA, pre-trained on a 52 billion token financial corpus, incorporating text, tables, and time-series data to embed comprehensive financial knowledge. FinLLaMA is then instruction fine-tuned with 573K financial instructions, resulting in FinLLaMA-instruct, which enhances task performance. Finally, we present FinLLaVA, a multimodal LLM trained with 1.43M image-text instructions to handle complex financial data types. Extensive evaluations demonstrate FinLLaMA's superior performance over LLaMA3-8B, LLaMA3.1-8B, and BloombergGPT in both zero-shot and few-shot settings across 19 and 4 datasets, respectively. FinLLaMA-instruct outperforms GPT-4 and other Financial LLMs on 15 datasets. FinLLaVA excels in understanding tables and charts across 4 multimodal tasks. Additionally, FinLLaMA achieves impressive Sharpe Ratios in trading simulations, highlighting its robust financial application capabilities. We will continually maintain and improve our models and benchmarks to support ongoing innovation in academia and industry.




Abstract:This technical report introduces Pegasus-1, a multimodal language model specialized in video content understanding and interaction through natural language. Pegasus-1 is designed to address the unique challenges posed by video data, such as interpreting spatiotemporal information, to offer nuanced video content comprehension across various lengths. This technical report overviews Pegasus-1's architecture, training strategies, and its performance in benchmarks on video conversation, zero-shot video question answering, and video summarization. We also explore qualitative characteristics of Pegasus-1 , demonstrating its capabilities as well as its limitations, in order to provide readers a balanced view of its current state and its future direction.




Abstract:Computed tomography is widely used to examine internal structures in a non-destructive manner. To obtain high-quality reconstructions, one typically has to acquire a densely sampled trajectory to avoid angular undersampling. However, many scenarios require a sparse-view measurement leading to streak-artifacts if unaccounted for. Current methods do not make full use of the domain-specific information, and hence fail to provide reliable reconstructions for highly undersampled data. We present a novel framework for sparse-view tomography by decoupling the reconstruction into two steps: First, we overcome its ill-posedness using a super-resolution network, SIN, trained on the sparse projections. The intermediate result allows for a closed-form tomographic reconstruction with preserved details and highly reduced streak-artifacts. Second, a refinement network, PRN, trained on the reconstructions reduces any remaining artifacts. We further propose a light-weight variant of the perceptual-loss that enhances domain-specific information, boosting restoration accuracy. Our experiments demonstrate an improvement over current solutions by 4 dB.




Abstract:Painting is an art form that has long functioned as a major channel for the creative expression and communication of humans, its evolution taking place under an interplay with the science, technology, and social environments of the times. Therefore, understanding the process based on comprehensive data could shed light on how humans acted and manifested creatively under changing conditions. Yet, there exist few systematic frameworks that characterize the process for painting, which would require robust statistical methods for defining painting characteristics and identifying human's creative developments, and data of high quality and sufficient quantity. Here we propose that the color contrast of a painting image signifying the heterogeneity in inter-pixel chromatic distance can be a useful representation of its style, integrating both the color and geometry. From the color contrasts of paintings from a large-scale, comprehensive archive of 179,853 high-quality images spanning several centuries we characterize the temporal evolutionary patterns of paintings, and present a deep study of an extraordinary expansion in creative diversity and individuality that came to define the modern era.