CHASE-SQL: Multi-Path Reasoning and Preference Optimized Candidate Selection in Text-to-SQL

In tackling the challenges of large language model (LLM) performance for Text-to-SQL tasks, we introduce CHASE-SQL, a new framework that employs innovative strategies, using test-time compute in multi-agent modeling to improve candidate generation and selection. CHASE-SQL leverages LLMs' intrinsic knowledge to generate diverse and high-quality SQL candidates using different LLM generators with: (1) a divide-and-conquer method that decomposes complex queries into manageable sub-queries in a single LLM call; (2) chain-of-thought reasoning based on query execution plans, reflecting the steps a database engine takes during execution; and (3) a unique instance-aware synthetic example generation technique, which offers specific few-shot demonstrations tailored to test questions.To identify the best candidate, a selection agent is employed to rank the candidates through pairwise comparisons with a fine-tuned binary-candidates selection LLM. This selection approach has been demonstrated to be more robust over alternatives. The proposed generators-selector framework not only enhances the quality and diversity of SQL queries but also outperforms previous methods. Overall, our proposed CHASE-SQL achieves the state-of-the-art execution accuracy of 73.0% and 73.01% on the test set and development set of the notable BIRD Text-to-SQL dataset benchmark, rendering CHASE-SQL the top submission of the leaderboard (at the time of paper submission).

A Two-Stage Proactive Dialogue Generator for Efficient Clinical Information Collection Using Large Language Model

Efficient patient-doctor interaction is among the key factors for a successful disease diagnosis. During the conversation, the doctor could query complementary diagnostic information, such as the patient's symptoms, previous surgery, and other related information that goes beyond medical evidence data (test results) to enhance disease diagnosis. However, this procedure is usually time-consuming and less-efficient, which can be potentially optimized through computer-assisted systems. As such, we propose a diagnostic dialogue system to automate the patient information collection procedure. By exploiting medical history and conversation logic, our conversation agents, particularly the doctor agent, can pose multi-round clinical queries to effectively collect the most relevant disease diagnostic information. Moreover, benefiting from our two-stage recommendation structure, carefully designed ranking criteria, and interactive patient agent, our model is able to overcome the under-exploration and non-flexible challenges in dialogue generation. Our experimental results on a real-world medical conversation dataset show that our model can generate clinical queries that mimic the conversation style of real doctors, with efficient fluency, professionalism, and safety, while effectively collecting relevant disease diagnostic information.

Enhancing Screen Time Identification in Children with a Multi-View Vision Language Model and Screen Time Tracker

Being able to accurately monitor the screen exposure of young children is important for research on phenomena linked to screen use such as childhood obesity, physical activity, and social interaction. Most existing studies rely upon self-report or manual measures from bulky wearable sensors, thus lacking efficiency and accuracy in capturing quantitative screen exposure data. In this work, we developed a novel sensor informatics framework that utilizes egocentric images from a wearable sensor, termed the screen time tracker (STT), and a vision language model (VLM). In particular, we devised a multi-view VLM that takes multiple views from egocentric image sequences and interprets screen exposure dynamically. We validated our approach by using a dataset of children's free-living activities, demonstrating significant improvement over existing methods in plain vision language models and object detection models. Results supported the promise of this monitoring approach, which could optimize behavioral research on screen exposure in children's naturalistic settings.

CardBench: A Benchmark for Learned Cardinality Estimation in Relational Databases

Cardinality estimation is crucial for enabling high query performance in relational databases. Recently learned cardinality estimation models have been proposed to improve accuracy but there is no systematic benchmark or datasets which allows researchers to evaluate the progress made by new learned approaches and even systematically develop new learned approaches. In this paper, we are releasing a benchmark, containing thousands of queries over 20 distinct real-world databases for learned cardinality estimation. In contrast to other initial benchmarks, our benchmark is much more diverse and can be used for training and testing learned models systematically. Using this benchmark, we explored whether learned cardinality estimation can be transferred to an unseen dataset in a zero-shot manner. We trained GNN-based and transformer-based models to study the problem in three setups: 1-) instance-based, 2-) zero-shot, and 3-) fine-tuned. Our results show that while we get promising results for zero-shot cardinality estimation on simple single table queries; as soon as we add joins, the accuracy drops. However, we show that with fine-tuning, we can still utilize pre-trained models for cardinality estimation, significantly reducing training overheads compared to instance specific models. We are open sourcing our scripts to collect statistics, generate queries and training datasets to foster more extensive research, also from the ML community on the important problem of cardinality estimation and in particular improve on recent directions such as pre-trained cardinality estimation.

Push the Boundary of SAM: A Pseudo-label Correction Framework for Medical Segmentation

Segment anything model (SAM) has emerged as the leading approach for zero-shot learning in segmentation, offering the advantage of avoiding pixel-wise annotation. It is particularly appealing in medical image segmentation where annotation is laborious and expertise-demanding. However, the direct application of SAM often yields inferior results compared to conventional fully supervised segmentation networks. While using SAM generated pseudo label could also benefit the training of fully supervised segmentation, the performance is limited by the quality of pseudo labels. In this paper, we propose a novel label corruption to push the boundary of SAM-based segmentation. Our model utilizes a novel noise detection module to distinguish between noisy labels from clean labels. This enables us to correct the noisy labels using an uncertainty-based self-correction module, thereby enriching the clean training set. Finally, we retrain the network with updated labels to optimize its weights for future predictions. One key advantage of our model is its ability to train deep networks using SAM-generated pseudo labels without relying on a subset of expert-level annotations. We demonstrate the effectiveness of our proposed model on both X-ray and lung CT datasets, indicating its ability to improve segmentation accuracy and outperform baseline methods in label correction.

SCPAT-GAN: Structural Constrained and Pathology Aware Convolutional Transformer-GAN for Virtual Histology Staining of Human Coronary OCT images

There is a significant need for the generation of virtual histological information from coronary optical coherence tomography (OCT) images to better guide the treatment of coronary artery disease. However, existing methods either require a large pixel-wisely paired training dataset or have limited capability to map pathological regions. To address these issues, we proposed a structural constrained, pathology aware, transformer generative adversarial network, namely SCPAT-GAN, to generate virtual stained H&E histology from OCT images. The proposed SCPAT-GAN advances existing methods via a novel design to impose pathological guidance on structural layers using transformer-based network.

Frequency-aware optical coherence tomography image super-resolution via conditional generative adversarial neural network

Optical coherence tomography (OCT) has stimulated a wide range of medical image-based diagnosis and treatment in fields such as cardiology and ophthalmology. Such applications can be further facilitated by deep learning-based super-resolution technology, which improves the capability of resolving morphological structures. However, existing deep learning-based method only focuses on spatial distribution and disregard frequency fidelity in image reconstruction, leading to a frequency bias. To overcome this limitation, we propose a frequency-aware super-resolution framework that integrates three critical frequency-based modules (i.e., frequency transformation, frequency skip connection, and frequency alignment) and frequency-based loss function into a conditional generative adversarial network (cGAN). We conducted a large-scale quantitative study from an existing coronary OCT dataset to demonstrate the superiority of our proposed framework over existing deep learning frameworks. In addition, we confirmed the generalizability of our framework by applying it to fish corneal images and rat retinal images, demonstrating its capability to super-resolve morphological details in eye imaging.

Detecting and measuring human gastric peristalsis using magnetically controlled capsule endoscope

Magnetically controlled capsule endoscope (MCCE) is an emerging tool for the diagnosis of gastric diseases with the advantages of comfort, safety, and no anesthesia. In this paper, we develop algorithms to detect and measure human gastric peristalsis (contraction wave) using video sequences acquired by MCCE. We develop a spatial-temporal deep learning algorithm to detect gastric contraction waves and measure human gastric peristalsis periods. The quality of MCCE video sequences is prone to camera motion. We design a camera motion detector (CMD) to process the MCCE video sequences, mitigating the camera movement during MCCE examination. To the best of our knowledge, we are the first to propose computer vision-based solutions to detect and measure human gastric peristalsis. Our methods have great potential in assisting the diagnosis of gastric diseases by evaluating gastric motility.

Structural constrained virtual histology staining for human coronary imaging using deep learning

Histopathological analysis is crucial in artery characterization for coronary artery disease (CAD). However, histology requires an invasive and time-consuming process. In this paper, we propose to generate virtual histology staining using Optical Coherence Tomography (OCT) images to enable real-time histological visualization. We develop a deep learning network, namely Coronary-GAN, to transfer coronary OCT images to virtual histology images. With a special consideration on the structural constraints in coronary OCT images, our method achieves better image generation performance than the conventional GAN-based method. The experimental results indicate that Coronary-GAN generates virtual histology images that are similar to real histology images, revealing the human coronary layers.

Towards reliable calcification detection: calibration of uncertainty in coronary optical coherence tomography images

Optical coherence tomography (OCT) has become increasingly essential in assisting the treatment of coronary artery disease (CAD). Image-guided solutions such as Percutaneous Coronary Intervention (PCI) are extensively used during the treatment of CAD. However, unidentified calcified regions within a narrowed artery could impair the outcome of the PCI. Prior to treatments, object detection is paramount to automatically procure accurate readings on the location and thickness of calcifications within the artery. Deep learning-based object detection methods have been explored in a variety of applications. The quality of object detection predictions could lead to uncertain results, which are not desirable in safety-critical scenarios. In this work, we implement an object detection model, You-Only-Look-Once v5 (YOLO), on a calcification detection framework within coronary OCT images. We evaluate the uncertainty of predictions based on the expected calibration errors, thus assessing the certainty level of detection results. To calibrate confidence scores of predictions, we implement dependent logistic calibration using each detection result's confidence and center coordinates. With the calibrated confidence score of each prediction, we lower the uncertainty of predictions in calcification detection. Our results show that the YOLO achieves higher precision and recall in comparison with the other object detection model, meanwhile producing more reliable results. The calibrated confidence of prediction results in a confidence error of approximately 0.13, suggesting that the confidence calibration on calcification detection could provide a more trustworthy result, indicating a great potential to assist clinical evaluation of treating the CAD during the imaging-guided procedure.