Generative Style Transfer for MRI Image Segmentation: A Case of Glioma Segmentation in Sub-Saharan Africa

In Sub-Saharan Africa (SSA), the utilization of lower-quality Magnetic Resonance Imaging (MRI) technology raises questions about the applicability of machine learning methods for clinical tasks. This study aims to provide a robust deep learning-based brain tumor segmentation (BraTS) method tailored for the SSA population using a threefold approach. Firstly, the impact of domain shift from the SSA training data on model efficacy was examined, revealing no significant effect. Secondly, a comparative analysis of 3D and 2D full-resolution models using the nnU-Net framework indicates similar performance of both the models trained for 300 epochs achieving a five-fold cross-validation score of 0.93. Lastly, addressing the performance gap observed in SSA validation as opposed to the relatively larger BraTS glioma (GLI) validation set, two strategies are proposed: fine-tuning SSA cases using the GLI+SSA best-pretrained 2D fullres model at 300 epochs, and introducing a novel neural style transfer-based data augmentation technique for the SSA cases. This investigation underscores the potential of enhancing brain tumor prediction within SSA's unique healthcare landscape.

Merging Context Clustering with Visual State Space Models for Medical Image Segmentation

Medical image segmentation demands the aggregation of global and local feature representations, posing a challenge for current methodologies in handling both long-range and short-range feature interactions. Recently, vision mamba (ViM) models have emerged as promising solutions for addressing model complexities by excelling in long-range feature iterations with linear complexity. However, existing ViM approaches overlook the importance of preserving short-range local dependencies by directly flattening spatial tokens and are constrained by fixed scanning patterns that limit the capture of dynamic spatial context information. To address these challenges, we introduce a simple yet effective method named context clustering ViM (CCViM), which incorporates a context clustering module within the existing ViM models to segment image tokens into distinct windows for adaptable local clustering. Our method effectively combines long-range and short-range feature interactions, thereby enhancing spatial contextual representations for medical image segmentation tasks. Extensive experimental evaluations on diverse public datasets, i.e., Kumar, CPM17, ISIC17, ISIC18, and Synapse demonstrate the superior performance of our method compared to current state-of-the-art methods. Our code can be found at https://github.com/zymissy/CCViM.

Generalized Task-Driven Medical Image Quality Enhancement with Gradient Promotion

Thanks to the recent achievements in task-driven image quality enhancement (IQE) models like ESTR, the image enhancement model and the visual recognition model can mutually enhance each other's quantitation while producing high-quality processed images that are perceivable by our human vision systems. However, existing task-driven IQE models tend to overlook an underlying fact -- different levels of vision tasks have varying and sometimes conflicting requirements of image features. To address this problem, this paper proposes a generalized gradient promotion (GradProm) training strategy for task-driven IQE of medical images. Specifically, we partition a task-driven IQE system into two sub-models, i.e., a mainstream model for image enhancement and an auxiliary model for visual recognition. During training, GradProm updates only parameters of the image enhancement model using gradients of the visual recognition model and the image enhancement model, but only when gradients of these two sub-models are aligned in the same direction, which is measured by their cosine similarity. In case gradients of these two sub-models are not in the same direction, GradProm only uses the gradient of the image enhancement model to update its parameters. Theoretically, we have proved that the optimization direction of the image enhancement model will not be biased by the auxiliary visual recognition model under the implementation of GradProm. Empirically, extensive experimental results on four public yet challenging medical image datasets demonstrated the superior performance of GradProm over existing state-of-the-art methods.

Parameter-efficient Fine-tuning for improved Convolutional Baseline for Brain Tumor Segmentation in Sub-Saharan Africa Adult Glioma Dataset

Automating brain tumor segmentation using deep learning methods is an ongoing challenge in medical imaging. Multiple lingering issues exist including domain-shift and applications in low-resource settings which brings a unique set of challenges including scarcity of data. As a step towards solving these specific problems, we propose Convolutional adapter-inspired Parameter-efficient Fine-tuning (PEFT) of MedNeXt architecture. To validate our idea, we show our method performs comparable to full fine-tuning with the added benefit of reduced training compute using BraTS-2021 as pre-training dataset and BraTS-Africa as the fine-tuning dataset. BraTS-Africa consists of a small dataset (60 train / 35 validation) from the Sub-Saharan African population with marked shift in the MRI quality compared to BraTS-2021 (1251 train samples). We first show that models trained on BraTS-2021 dataset do not generalize well to BraTS-Africa as shown by 20% reduction in mean dice on BraTS-Africa validation samples. Then, we show that PEFT can leverage both the BraTS-2021 and BraTS-Africa dataset to obtain mean dice of 0.8 compared to 0.72 when trained only on BraTS-Africa. Finally, We show that PEFT (0.80 mean dice) results in comparable performance to full fine-tuning (0.77 mean dice) which may show PEFT to be better on average but the boxplots show that full finetuning results is much lesser variance in performance. Nevertheless, on disaggregation of the dice metrics, we find that the model has tendency to oversegment as shown by high specificity (0.99) compared to relatively low sensitivity(0.75). The source code is available at https://github.com/CAMERA-MRI/SPARK2024/tree/main/PEFT_MedNeXt

Divide-and-Conquer: Confluent Triple-Flow Network for RGB-T Salient Object Detection

RGB-Thermal Salient Object Detection aims to pinpoint prominent objects within aligned pairs of visible and thermal infrared images. Traditional encoder-decoder architectures, while designed for cross-modality feature interactions, may not have adequately considered the robustness against noise originating from defective modalities. Inspired by hierarchical human visual systems, we propose the ConTriNet, a robust Confluent Triple-Flow Network employing a Divide-and-Conquer strategy. Specifically, ConTriNet comprises three flows: two modality-specific flows explore cues from RGB and Thermal modalities, and a third modality-complementary flow integrates cues from both modalities. ConTriNet presents several notable advantages. It incorporates a Modality-induced Feature Modulator in the modality-shared union encoder to minimize inter-modality discrepancies and mitigate the impact of defective samples. Additionally, a foundational Residual Atrous Spatial Pyramid Module in the separated flows enlarges the receptive field, allowing for the capture of multi-scale contextual information. Furthermore, a Modality-aware Dynamic Aggregation Module in the modality-complementary flow dynamically aggregates saliency-related cues from both modality-specific flows. Leveraging the proposed parallel triple-flow framework, we further refine saliency maps derived from different flows through a flow-cooperative fusion strategy, yielding a high-quality, full-resolution saliency map for the final prediction. To evaluate the robustness and stability of our approach, we collect a comprehensive RGB-T SOD benchmark, VT-IMAG, covering various real-world challenging scenarios. Extensive experiments on public benchmarks and our VT-IMAG dataset demonstrate that ConTriNet consistently outperforms state-of-the-art competitors in both common and challenging scenarios.

MME-Finance: A Multimodal Finance Benchmark for Expert-level Understanding and Reasoning

In recent years, multimodal benchmarks for general domains have guided the rapid development of multimodal models on general tasks. However, the financial field has its peculiarities. It features unique graphical images (e.g., candlestick charts, technical indicator charts) and possesses a wealth of specialized financial knowledge (e.g., futures, turnover rate). Therefore, benchmarks from general fields often fail to measure the performance of multimodal models in the financial domain, and thus cannot effectively guide the rapid development of large financial models. To promote the development of large financial multimodal models, we propose MME-Finance, an bilingual open-ended and practical usage-oriented Visual Question Answering (VQA) benchmark. The characteristics of our benchmark are finance and expertise, which include constructing charts that reflect the actual usage needs of users (e.g., computer screenshots and mobile photography), creating questions according to the preferences in financial domain inquiries, and annotating questions by experts with 10+ years of experience in the financial industry. Additionally, we have developed a custom-designed financial evaluation system in which visual information is first introduced in the multi-modal evaluation process. Extensive experimental evaluations of 19 mainstream MLLMs are conducted to test their perception, reasoning, and cognition capabilities. The results indicate that models performing well on general benchmarks cannot do well on MME-Finance; for instance, the top-performing open-source and closed-source models obtain 65.69 (Qwen2VL-72B) and 63.18 (GPT-4o), respectively. Their performance is particularly poor in categories most relevant to finance, such as candlestick charts and technical indicator charts. In addition, we propose a Chinese version, which helps compare performance of MLLMs under a Chinese context.

A Survey on Bundle Recommendation: Methods, Applications, and Challenges

In recent years, bundle recommendation systems have gained significant attention in both academia and industry due to their ability to enhance user experience and increase sales by recommending a set of items as a bundle rather than individual items. This survey provides a comprehensive review on bundle recommendation, beginning by a taxonomy for exploring product bundling. We classify it into two categories based on bundling strategy from various application domains, i.e., discriminative and generative bundle recommendation. Then we formulate the corresponding tasks of the two categories and systematically review their methods: 1) representation learning from bundle and item levels and interaction modeling for discriminative bundle recommendation; 2) representation learning from item level and bundle generation for generative bundle recommendation. Subsequently, we survey the resources of bundle recommendation including datasets and evaluation metrics, and conduct reproducibility experiments on mainstream models. Lastly, we discuss the main challenges and highlight the promising future directions in the field of bundle recommendation, aiming to serve as a useful resource for researchers and practitioners. Our code and datasets are publicly available at https://github.com/WUT-IDEA/bundle-recommendation-survey.

BitStack: Fine-Grained Size Control for Compressed Large Language Models in Variable Memory Environments

Large language models (LLMs) have revolutionized numerous applications, yet their deployment remains challenged by memory constraints on local devices. While scaling laws have enhanced LLM capabilities, the primary bottleneck has shifted from \textit{capability} to \textit{availability}, emphasizing the need for efficient memory management. Traditional compression methods, such as quantization, often require predefined compression ratios and separate compression processes for each setting, complicating deployment in variable memory environments. In this paper, we introduce \textbf{BitStack}, a novel, training-free weight compression approach that enables megabyte-level trade-offs between memory usage and model performance. By leveraging weight decomposition, BitStack can dynamically adjust the model size with minimal transmission between running memory and storage devices. Our approach iteratively decomposes weight matrices while considering the significance of each parameter, resulting in an approximately 1-bit per parameter residual block in each decomposition iteration. These blocks are sorted and stacked in storage as basic transmission units, with different quantities loaded based on current memory availability. Extensive experiments across a wide range of tasks demonstrate that, despite offering fine-grained size control, BitStack consistently matches or surpasses strong quantization baselines, particularly at extreme compression ratios. To the best of our knowledge, this is the first decomposition-based method that effectively bridges the gap to practical compression techniques like quantization. Code is available at https://github.com/xinghaow99/BitStack.

MetaAlign: Align Large Language Models with Diverse Preferences during Inference Time

Large Language Models (LLMs) acquire extensive knowledge and remarkable abilities from extensive text corpora, making them powerful tools for various applications. To make LLMs more usable, aligning them with human preferences is essential. Existing alignment techniques, such as Reinforcement Learning from Human Feedback (RLHF) and Direct Preference Optimization (DPO), typically embed predefined preferences directly within the model's parameters. These methods, however, often result in a static alignment that can not account for the diversity of human preferences in practical applications. In response to this challenge, we propose an effective method, \textbf{MetaAlign}, which aims to help LLMs dynamically align with various explicit or implicit preferences specified at inference time. Experimental results show that LLMs optimized on our meticulously constructed MetaAlign Dataset can effectively align with any preferences specified at the inference stage, validating the feasibility of MetaAlign. We hope that our work can provide some insights into the alignment of language models.

IntrinsicVoice: Empowering LLMs with Intrinsic Real-time Voice Interaction Abilities

Current methods of building LLMs with voice interaction capabilities rely heavily on explicit text autoregressive generation before or during speech response generation to maintain content quality, which unfortunately brings computational overhead and increases latency in multi-turn interactions. To address this, we introduce IntrinsicVoic,e an LLM designed with intrinsic real-time voice interaction capabilities. IntrinsicVoice aims to facilitate the transfer of textual capabilities of pre-trained LLMs to the speech modality by mitigating the modality gap between text and speech. Our novelty architecture, GroupFormer, can reduce speech sequences to lengths comparable to text sequences while generating high-quality audio, significantly reducing the length difference between speech and text, speeding up inference, and alleviating long-text modeling issues. Additionally, we construct a multi-turn speech-to-speech dialogue dataset named \method-500k which includes nearly 500k turns of speech-to-speech dialogues, and a cross-modality training strategy to enhance the semantic alignment between speech and text. Experimental results demonstrate that IntrinsicVoice can generate high-quality speech response with latency lower than 100ms in multi-turn dialogue scenarios. Demos are available at https://instrinsicvoice.github.io/.