GBR: Generative Bundle Refinement for High-fidelity Gaussian Splatting and Meshing

Gaussian splatting has gained attention for its efficient representation and rendering of 3D scenes using continuous Gaussian primitives. However, it struggles with sparse-view inputs due to limited geometric and photometric information, causing ambiguities in depth, shape, and texture. we propose GBR: Generative Bundle Refinement, a method for high-fidelity Gaussian splatting and meshing using only 4-6 input views. GBR integrates a neural bundle adjustment module to enhance geometry accuracy and a generative depth refinement module to improve geometry fidelity. More specifically, the neural bundle adjustment module integrates a foundation network to produce initial 3D point maps and point matches from unposed images, followed by bundle adjustment optimization to improve multiview consistency and point cloud accuracy. The generative depth refinement module employs a diffusion-based strategy to enhance geometric details and fidelity while preserving the scale. Finally, for Gaussian splatting optimization, we propose a multimodal loss function incorporating depth and normal consistency, geometric regularization, and pseudo-view supervision, providing robust guidance under sparse-view conditions. Experiments on widely used datasets show that GBR significantly outperforms existing methods under sparse-view inputs. Additionally, GBR demonstrates the ability to reconstruct and render large-scale real-world scenes, such as the Pavilion of Prince Teng and the Great Wall, with remarkable details using only 6 views.

Multimodal 3D Brain Tumor Segmentation with Adversarial Training and Conditional Random Field

Accurate brain tumor segmentation remains a challenging task due to structural complexity and great individual differences of gliomas. Leveraging the pre-eminent detail resilience of CRF and spatial feature extraction capacity of V-net, we propose a multimodal 3D Volume Generative Adversarial Network (3D-vGAN) for precise segmentation. The model utilizes Pseudo-3D for V-net improvement, adds conditional random field after generator and use original image as supplemental guidance. Results, using the BraTS-2018 dataset, show that 3D-vGAN outperforms classical segmentation models, including U-net, Gan, FCN and 3D V-net, reaching specificity over 99.8%.

Application of Graph Based Features in Computer Aided Diagnosis for Histopathological Image Classification of Gastric Cancer

The gold standard for gastric cancer detection is gastric histopathological image analysis, but there are certain drawbacks in the existing histopathological detection and diagnosis. In this paper, based on the study of computer aided diagnosis system, graph based features are applied to gastric cancer histopathology microscopic image analysis, and a classifier is used to classify gastric cancer cells from benign cells. Firstly, image segmentation is performed, and after finding the region, cell nuclei are extracted using the k-means method, the minimum spanning tree (MST) is drawn, and graph based features of the MST are extracted. The graph based features are then put into the classifier for classification. In this study, different segmentation methods are compared in the tissue segmentation stage, among which are Level-Set, Otsu thresholding, watershed, SegNet, U-Net and Trans-U-Net segmentation; Graph based features, Red, Green, Blue features, Grey-Level Co-occurrence Matrix features, Histograms of Oriented Gradient features and Local Binary Patterns features are compared in the feature extraction stage; Radial Basis Function (RBF) Support Vector Machine (SVM), Linear SVM, Artificial Neural Network, Random Forests, k-NearestNeighbor, VGG16, and Inception-V3 are compared in the classifier stage. It is found that using U-Net to segment tissue areas, then extracting graph based features, and finally using RBF SVM classifier gives the optimal results with 94.29%.

Application of Transfer Learning and Ensemble Learning in Image-level Classification for Breast Histopathology

Background: Breast cancer has the highest prevalence in women globally. The classification and diagnosis of breast cancer and its histopathological images have always been a hot spot of clinical concern. In Computer-Aided Diagnosis (CAD), traditional classification models mostly use a single network to extract features, which has significant limitations. On the other hand, many networks are trained and optimized on patient-level datasets, ignoring the application of lower-level data labels. Method: This paper proposes a deep ensemble model based on image-level labels for the binary classification of benign and malignant lesions of breast histopathological images. First, the BreakHis dataset is randomly divided into a training, validation and test set. Then, data augmentation techniques are used to balance the number of benign and malignant samples. Thirdly, considering the performance of transfer learning and the complementarity between each network, VGG-16, Xception, Resnet-50, DenseNet-201 are selected as the base classifiers. Result: In the ensemble network model with accuracy as the weight, the image-level binary classification achieves an accuracy of $98.90\%$. In order to verify the capabilities of our method, the latest Transformer and Multilayer Perception (MLP) models have been experimentally compared on the same dataset. Our model wins with a $5\%-20\%$ advantage, emphasizing the ensemble model's far-reaching significance in classification tasks. Conclusion: This research focuses on improving the model's classification performance with an ensemble algorithm. Transfer learning plays an essential role in small datasets, improving training speed and accuracy. Our model has outperformed many existing approaches in accuracy, providing a method for the field of auxiliary medical diagnosis.