Agent Aggregator with Mask Denoise Mechanism for Histopathology Whole Slide Image Analysis

Histopathology analysis is the gold standard for medical diagnosis. Accurate classification of whole slide images (WSIs) and region-of-interests (ROIs) localization can assist pathologists in diagnosis. The gigapixel resolution of WSI and the absence of fine-grained annotations make direct classification and analysis challenging. In weakly supervised learning, multiple instance learning (MIL) presents a promising approach for WSI classification. The prevailing strategy is to use attention mechanisms to measure instance importance for classification. However, attention mechanisms fail to capture inter-instance information, and self-attention causes quadratic computational complexity. To address these challenges, we propose AMD-MIL, an agent aggregator with a mask denoise mechanism. The agent token acts as an intermediate variable between the query and key for computing instance importance. Mask and denoising matrices, mapped from agents-aggregated value, dynamically mask low-contribution representations and eliminate noise. AMD-MIL achieves better attention allocation by adjusting feature representations, capturing micro-metastases in cancer, and improving interpretability. Extensive experiments on CAMELYON-16, CAMELYON-17, TCGA-KIDNEY, and TCGA-LUNG show AMD-MIL's superiority over state-of-the-art methods.

Scaffolding Coordinates to Promote Vision-Language Coordination in Large Multi-Modal Models

State-of-the-art Large Multi-Modal Models (LMMs) have demonstrated exceptional capabilities in vision-language tasks. Despite their advanced functionalities, the performances of LMMs are still limited in challenging scenarios that require complex reasoning with multiple levels of visual information. Existing prompting techniques for LMMs focus on either improving textual reasoning or leveraging tools for image preprocessing, lacking a simple and general visual prompting scheme to promote vision-language coordination in LMMs. In this work, we propose Scaffold prompting that scaffolds coordinates to promote vision-language coordination. Specifically, Scaffold overlays a dot matrix within the image as visual information anchors and leverages multi-dimensional coordinates as textual positional references. Extensive experiments on a wide range of challenging vision-language tasks demonstrate the superiority of Scaffold over GPT-4V with the textual CoT prompting. Our code is released in https://github.com/leixy20/Scaffold.

Towards Unified Alignment Between Agents, Humans, and Environment

The rapid progress of foundation models has led to the prosperity of autonomous agents, which leverage the universal capabilities of foundation models to conduct reasoning, decision-making, and environmental interaction. However, the efficacy of agents remains limited when operating in intricate, realistic environments. In this work, we introduce the principles of $\mathbf{U}$nified $\mathbf{A}$lignment for $\mathbf{A}$gents ($\mathbf{UA}^2$), which advocate for the simultaneous alignment of agents with human intentions, environmental dynamics, and self-constraints such as the limitation of monetary budgets. From the perspective of $\mathbf{UA}^2$, we review the current agent research and highlight the neglected factors in existing agent benchmarks and method candidates. We also conduct proof-of-concept studies by introducing realistic features to WebShop, including user profiles to demonstrate intentions, personalized reranking for complex environmental dynamics, and runtime cost statistics to reflect self-constraints. We then follow the principles of $\mathbf{UA}^2$ to propose an initial design of our agent, and benchmark its performance with several candidate baselines in the retrofitted WebShop. The extensive experimental results further prove the importance of the principles of $\mathbf{UA}^2$. Our research sheds light on the next steps of autonomous agent research with improved general problem-solving abilities.

A XGBoost Algorithm-based Fatigue Recognition Model Using Face Detection

As fatigue is normally revealed in the eyes and mouth of a person's face, this paper tried to construct a XGBoost Algorithm-Based fatigue recognition model using the two indicators, EAR (Eye Aspect Ratio) and MAR(Mouth Aspect Ratio). With an accuracy rate of 87.37% and sensitivity rate of 89.14%, the model was proved to be efficient and valid for further applications.