SDoH-GPT: Using Large Language Models to Extract Social Determinants of Health (SDoH)

Extracting social determinants of health (SDoH) from unstructured medical notes depends heavily on labor-intensive annotations, which are typically task-specific, hampering reusability and limiting sharing. In this study we introduced SDoH-GPT, a simple and effective few-shot Large Language Model (LLM) method leveraging contrastive examples and concise instructions to extract SDoH without relying on extensive medical annotations or costly human intervention. It achieved tenfold and twentyfold reductions in time and cost respectively, and superior consistency with human annotators measured by Cohen's kappa of up to 0.92. The innovative combination of SDoH-GPT and XGBoost leverages the strengths of both, ensuring high accuracy and computational efficiency while consistently maintaining 0.90+ AUROC scores. Testing across three distinct datasets has confirmed its robustness and accuracy. This study highlights the potential of leveraging LLMs to revolutionize medical note classification, demonstrating their capability to achieve highly accurate classifications with significantly reduced time and cost.

Language Models Still Struggle to Zero-shot Reason about Time Series

Time series are critical for decision-making in fields like finance and healthcare. Their importance has driven a recent influx of works passing time series into language models, leading to non-trivial forecasting on some datasets. But it remains unknown whether non-trivial forecasting implies that language models can reason about time series. To address this gap, we generate a first-of-its-kind evaluation framework for time series reasoning, including formal tasks and a corresponding dataset of multi-scale time series paired with text captions across ten domains. Using these data, we probe whether language models achieve three forms of reasoning: (1) Etiological Reasoning - given an input time series, can the language model identify the scenario that most likely created it? (2) Question Answering - can a language model answer factual questions about time series? (3) Context-Aided Forecasting - does highly relevant textual context improve a language model's time series forecasts? We find that otherwise highly-capable language models demonstrate surprisingly limited time series reasoning: they score marginally above random on etiological and question answering tasks (up to 30 percentage points worse than humans) and show modest success in using context to improve forecasting. These weakness showcase that time series reasoning is an impactful, yet deeply underdeveloped direction for language model research. We also make our datasets and code public at to support further research in this direction at https://github.com/behavioral-data/TSandLanguage

Recent Advances, Applications, and Open Challenges in Machine Learning for Health: Reflections from Research Roundtables at ML4H 2023 Symposium

The third ML4H symposium was held in person on December 10, 2023, in New Orleans, Louisiana, USA. The symposium included research roundtable sessions to foster discussions between participants and senior researchers on timely and relevant topics for the \ac{ML4H} community. Encouraged by the successful virtual roundtables in the previous year, we organized eleven in-person roundtables and four virtual roundtables at ML4H 2022. The organization of the research roundtables at the conference involved 17 Senior Chairs and 19 Junior Chairs across 11 tables. Each roundtable session included invited senior chairs (with substantial experience in the field), junior chairs (responsible for facilitating the discussion), and attendees from diverse backgrounds with interest in the session's topic. Herein we detail the organization process and compile takeaways from these roundtable discussions, including recent advances, applications, and open challenges for each topic. We conclude with a summary and lessons learned across all roundtables. This document serves as a comprehensive review paper, summarizing the recent advancements in machine learning for healthcare as contributed by foremost researchers in the field.