Multimodal Outer Arithmetic Block Dual Fusion of Whole Slide Images and Omics Data for Precision Oncology

Developing a central nervous system (CNS) tumor classifier by integrating DNA methylation data with Whole Slide Images (WSI) offers significant potential for enhancing diagnostic precision in neuropathology. Existing approaches typically integrate encoded omic data with histology only once - either at an early or late fusion stage - while reintroducing encoded omic data to create a dual fusion variant remains unexplored. Nevertheless, reintroduction of omic embeddings during early and late fusion enables the capture of complementary information from localized patch-level and holistic slide-level interactions, allowing boosted performance through advanced multimodal integration. To achieve this, we propose a dual fusion framework that integrates omic data at both early and late stages, fully leveraging its diagnostic strength. In the early fusion stage, omic embeddings are projected into a patch-wise latent space, generating omic-WSI embeddings that encapsulate per-patch molecular and morphological insights, effectively incorporating this information into the spatial representation of histology. These embeddings are refined with a multiple instance learning gated attention mechanism to attend to critical patches. In the late fusion stage, we reintroduce the omic data by fusing it with slide-level omic-WSI embeddings using a Multimodal Outer Arithmetic Block (MOAB), which richly intermingles features from both modalities, capturing their global correlations and complementarity. We demonstrate accurate CNS tumor subtyping across 20 fine-grained subtypes and validate our approach on benchmark datasets, achieving improved survival prediction on TCGA-BLCA and competitive performance on TCGA-BRCA compared to state-of-the-art methods. This dual fusion strategy enhances interpretability and classification performance, highlighting its potential for clinical diagnostics.

ReWind: Understanding Long Videos with Instructed Learnable Memory

Vision-Language Models (VLMs) are crucial for applications requiring integrated understanding textual and visual information. However, existing VLMs struggle with long videos due to computational inefficiency, memory limitations, and difficulties in maintaining coherent understanding across extended sequences. To address these challenges, we introduce ReWind, a novel memory-based VLM designed for efficient long video understanding while preserving temporal fidelity. ReWind operates in a two-stage framework. In the first stage, ReWind maintains a dynamic learnable memory module with a novel \textbf{read-perceive-write} cycle that stores and updates instruction-relevant visual information as the video unfolds. This module utilizes learnable queries and cross-attentions between memory contents and the input stream, ensuring low memory requirements by scaling linearly with the number of tokens. In the second stage, we propose an adaptive frame selection mechanism guided by the memory content to identify instruction-relevant key moments. It enriches the memory representations with detailed spatial information by selecting a few high-resolution frames, which are then combined with the memory contents and fed into a Large Language Model (LLM) to generate the final answer. We empirically demonstrate ReWind's superior performance in visual question answering (VQA) and temporal grounding tasks, surpassing previous methods on long video benchmarks. Notably, ReWind achieves a +13\% score gain and a +12\% accuracy improvement on the MovieChat-1K VQA dataset and an +8\% mIoU increase on Charades-STA for temporal grounding.

CemiFace: Center-based Semi-hard Synthetic Face Generation for Face Recognition

Privacy issue is a main concern in developing face recognition techniques. Although synthetic face images can partially mitigate potential legal risks while maintaining effective face recognition (FR) performance, FR models trained by face images synthesized by existing generative approaches frequently suffer from performance degradation problems due to the insufficient discriminative quality of these synthesized samples. In this paper, we systematically investigate what contributes to solid face recognition model training, and reveal that face images with certain degree of similarities to their identity centers show great effectiveness in the performance of trained FR models. Inspired by this, we propose a novel diffusion-based approach (namely Center-based Semi-hard Synthetic Face Generation (CemiFace)) which produces facial samples with various levels of similarity to the subject center, thus allowing to generate face datasets containing effective discriminative samples for training face recognition. Experimental results show that with a modest degree of similarity, training on the generated dataset can produce competitive performance compared to previous generation methods.

Behaviour4All: in-the-wild Facial Behaviour Analysis Toolkit

In this paper, we introduce Behavior4All, a comprehensive, open-source toolkit for in-the-wild facial behavior analysis, integrating Face Localization, Valence-Arousal Estimation, Basic Expression Recognition and Action Unit Detection, all within a single framework. Available in both CPU-only and GPU-accelerated versions, Behavior4All leverages 12 large-scale, in-the-wild datasets consisting of over 5 million images from diverse demographic groups. It introduces a novel framework that leverages distribution matching and label co-annotation to address tasks with non-overlapping annotations, encoding prior knowledge of their relatedness. In the largest study of its kind, Behavior4All outperforms both state-of-the-art and toolkits in overall performance as well as fairness across all databases and tasks. It also demonstrates superior generalizability on unseen databases and on compound expression recognition. Finally, Behavior4All is way times faster than other toolkits.

MM2Latent: Text-to-facial image generation and editing in GANs with multimodal assistance

Generating human portraits is a hot topic in the image generation area, e.g. mask-to-face generation and text-to-face generation. However, these unimodal generation methods lack controllability in image generation. Controllability can be enhanced by exploring the advantages and complementarities of various modalities. For instance, we can utilize the advantages of text in controlling diverse attributes and masks in controlling spatial locations. Current state-of-the-art methods in multimodal generation face limitations due to their reliance on extensive hyperparameters, manual operations during the inference stage, substantial computational demands during training and inference, or inability to edit real images. In this paper, we propose a practical framework - MM2Latent - for multimodal image generation and editing. We use StyleGAN2 as our image generator, FaRL for text encoding, and train an autoencoders for spatial modalities like mask, sketch and 3DMM. We propose a strategy that involves training a mapping network to map the multimodal input into the w latent space of StyleGAN. The proposed framework 1) eliminates hyperparameters and manual operations in the inference stage, 2) ensures fast inference speeds, and 3) enables the editing of real images. Extensive experiments demonstrate that our method exhibits superior performance in multimodal image generation, surpassing recent GAN- and diffusion-based methods. Also, it proves effective in multimodal image editing and is faster than GAN- and diffusion-based methods. We make the code publicly available at: https://github.com/Open-Debin/MM2Latent

CLIPCleaner: Cleaning Noisy Labels with CLIP

Learning with Noisy labels (LNL) poses a significant challenge for the Machine Learning community. Some of the most widely used approaches that select as clean samples for which the model itself (the in-training model) has high confidence, e.g., `small loss', can suffer from the so called `self-confirmation' bias. This bias arises because the in-training model, is at least partially trained on the noisy labels. Furthermore, in the classification case, an additional challenge arises because some of the label noise is between classes that are visually very similar (`hard noise'). This paper addresses these challenges by proposing a method (\textit{CLIPCleaner}) that leverages CLIP, a powerful Vision-Language (VL) model for constructing a zero-shot classifier for efficient, offline, clean sample selection. This has the advantage that the sample selection is decoupled from the in-training model and that the sample selection is aware of the semantic and visual similarities between the classes due to the way that CLIP is trained. We provide theoretical justifications and empirical evidence to demonstrate the advantages of CLIP for LNL compared to conventional pre-trained models. Compared to current methods that combine iterative sample selection with various techniques, \textit{CLIPCleaner} offers a simple, single-step approach that achieves competitive or superior performance on benchmark datasets. To the best of our knowledge, this is the first time a VL model has been used for sample selection to address the problem of Learning with Noisy Labels (LNL), highlighting their potential in the domain.

Are CLIP features all you need for Universal Synthetic Image Origin Attribution?

The steady improvement of Diffusion Models for visual synthesis has given rise to many new and interesting use cases of synthetic images but also has raised concerns about their potential abuse, which poses significant societal threats. To address this, fake images need to be detected and attributed to their source model, and given the frequent release of new generators, realistic applications need to consider an Open-Set scenario where some models are unseen at training time. Existing forensic techniques are either limited to Closed-Set settings or to GAN-generated images, relying on fragile frequency-based "fingerprint" features. By contrast, we propose a simple yet effective framework that incorporates features from large pre-trained foundation models to perform Open-Set origin attribution of synthetic images produced by various generative models, including Diffusion Models. We show that our method leads to remarkable attribution performance, even in the low-data regime, exceeding the performance of existing methods and generalizes better on images obtained from a diverse set of architectures. We make the code publicly available at: https://github.com/ciodar/UniversalAttribution.

Get Confused Cautiously: Textual Sequence Memorization Erasure with Selective Entropy Maximization

Large Language Models (LLMs) have been found to memorize and recite some of the textual sequences from their training set verbatim, raising broad concerns about privacy and copyright issues when using LLMs. This Textual Sequence Memorization (TSM) phenomenon leads to a high demand to regulate LLM output to prevent it from generating certain memorized text to meet user requirements. However, our empirical study reveals that existing methods for TSM erasure fail to forget massive memorized samples without substantially jeopardizing the model utility. To achieve a better trade-off between the effectiveness of TSM erasure and model utility in LLMs, our paper proposes a new framework based on Entropy Maximization with Selective Optimization (EMSO), where the updated weights are chosen with a novel contrastive gradient metric without any participation of additional model or data. Our analysis shows that training with the entropy maximization loss has a more stable optimization process and better keeps model utility than existing methods. The contrastive gradient metric localizes the most influential weight for TSM erasure by taking both the gradient magnitude and direction into consideration. Extensive experiments across three model scales demonstrate that our method excels in handling large-scale forgetting requests while preserving model ability in language generation and reasoning.

Multimodal Machine Learning in Mental Health: A Survey of Data, Algorithms, and Challenges

The application of machine learning (ML) in detecting, diagnosing, and treating mental health disorders is garnering increasing attention. Traditionally, research has focused on single modalities, such as text from clinical notes, audio from speech samples, or video of interaction patterns. Recently, multimodal ML, which combines information from multiple modalities, has demonstrated significant promise in offering novel insights into human behavior patterns and recognizing mental health symptoms and risk factors. Despite its potential, multimodal ML in mental health remains an emerging field, facing several complex challenges before practical applications can be effectively developed. This survey provides a comprehensive overview of the data availability and current state-of-the-art multimodal ML applications for mental health. It discusses key challenges that must be addressed to advance the field. The insights from this survey aim to deepen the understanding of the potential and limitations of multimodal ML in mental health, guiding future research and development in this evolving domain.

Efficient Unsupervised Visual Representation Learning with Explicit Cluster Balancing

Self-supervised learning has recently emerged as the preeminent pretraining paradigm across and between modalities, with remarkable results. In the image domain specifically, group (or cluster) discrimination has been one of the most successful methods. However, such frameworks need to guard against heavily imbalanced cluster assignments to prevent collapse to trivial solutions. Existing works typically solve this by reweighing cluster assignments to promote balance, or with offline operations (e.g. regular re-clustering) that prevent collapse. However, the former typically requires large batch sizes, which leads to increased resource requirements, and the latter introduces scalability issues with regard to large datasets. In this work, we propose ExCB, a framework that tackles this problem with a novel cluster balancing method. ExCB estimates the relative size of the clusters across batches and balances them by adjusting cluster assignments, proportionately to their relative size and in an online manner. Thereby, it overcomes previous methods' dependence on large batch sizes and is fully online, and therefore scalable to any dataset. We conduct extensive experiments to evaluate our approach and demonstrate that ExCB: a) achieves state-of-the-art results with significantly reduced resource requirements compared to previous works, b) is fully online, and therefore scalable to large datasets, and c) is stable and effective even with very small batch sizes.