STaR: Seamless Spatial-Temporal Aware Motion Retargeting with Penetration and Consistency Constraints

Motion retargeting seeks to faithfully replicate the spatio-temporal motion characteristics of a source character onto a target character with a different body shape. Apart from motion semantics preservation, ensuring geometric plausibility and maintaining temporal consistency are also crucial for effective motion retargeting. However, many existing methods prioritize either geometric plausibility or temporal consistency. Neglecting geometric plausibility results in interpenetration while neglecting temporal consistency leads to motion jitter. In this paper, we propose a novel sequence-to-sequence model for seamless Spatial-Temporal aware motion Retargeting (STaR), with penetration and consistency constraints. STaR consists of two modules: (1) a spatial module that incorporates dense shape representation and a novel limb penetration constraint to ensure geometric plausibility while preserving motion semantics, and (2) a temporal module that utilizes a temporal transformer and a novel temporal consistency constraint to predict the entire motion sequence at once while enforcing multi-level trajectory smoothness. The seamless combination of the two modules helps us achieve a good balance between the semantic, geometric, and temporal targets. Extensive experiments on the Mixamo and ScanRet datasets demonstrate that our method produces plausible and coherent motions while significantly reducing interpenetration rates compared with other approaches.

BioX-CPath: Biologically-driven Explainable Diagnostics for Multistain IHC Computational Pathology

The development of biologically interpretable and explainable models remains a key challenge in computational pathology, particularly for multistain immunohistochemistry (IHC) analysis. We present BioX-CPath, an explainable graph neural network architecture for whole slide image (WSI) classification that leverages both spatial and semantic features across multiple stains. At its core, BioX-CPath introduces a novel Stain-Aware Attention Pooling (SAAP) module that generates biologically meaningful, stain-aware patient embeddings. Our approach achieves state-of-the-art performance on both Rheumatoid Arthritis and Sjogren's Disease multistain datasets. Beyond performance metrics, BioX-CPath provides interpretable insights through stain attention scores, entropy measures, and stain interaction scores, that permit measuring model alignment with known pathological mechanisms. This biological grounding, combined with strong classification performance, makes BioX-CPath particularly suitable for clinical applications where interpretability is key. Source code and documentation can be found at: https://github.com/AmayaGS/BioX-CPath.

HandSplat: Embedding-Driven Gaussian Splatting for High-Fidelity Hand Rendering

Existing 3D Gaussian Splatting (3DGS) methods for hand rendering rely on rigid skeletal motion with an oversimplified non-rigid motion model, which fails to capture fine geometric and appearance details. Additionally, they perform densification based solely on per-point gradients and process poses independently, ignoring spatial and temporal correlations. These limitations lead to geometric detail loss, temporal instability, and inefficient point distribution. To address these issues, we propose HandSplat, a novel Gaussian Splatting-based framework that enhances both fidelity and stability for hand rendering. To improve fidelity, we extend standard 3DGS attributes with implicit geometry and appearance embeddings for finer non-rigid motion modeling while preserving the static hand characteristic modeled by original 3DGS attributes. Additionally, we introduce a local gradient-aware densification strategy that dynamically refines Gaussian density in high-variation regions. To improve stability, we incorporate pose-conditioned attribute regularization to encourage attribute consistency across similar poses, mitigating temporal artifacts. Extensive experiments on InterHand2.6M demonstrate that HandSplat surpasses existing methods in fidelity and stability while achieving real-time performance. We will release the code and pre-trained models upon acceptance.

SuperCap: Multi-resolution Superpixel-based Image Captioning

It has been a longstanding goal within image captioning to move beyond a dependence on object detection. We investigate using superpixels coupled with Vision Language Models (VLMs) to bridge the gap between detector-based captioning architectures and those that solely pretrain on large datasets. Our novel superpixel approach ensures that the model receives object-like features whilst the use of VLMs provides our model with open set object understanding. Furthermore, we extend our architecture to make use of multi-resolution inputs, allowing our model to view images in different levels of detail, and use an attention mechanism to determine which parts are most relevant to the caption. We demonstrate our model's performance with multiple VLMs and through a range of ablations detailing the impact of different architectural choices. Our full model achieves a competitive CIDEr score of $136.9$ on the COCO Karpathy split.

HanDrawer: Leveraging Spatial Information to Render Realistic Hands Using a Conditional Diffusion Model in Single Stage

Although diffusion methods excel in text-to-image generation, generating accurate hand gestures remains a major challenge, resulting in severe artifacts, such as incorrect number of fingers or unnatural gestures. To enable the diffusion model to learn spatial information to improve the quality of the hands generated, we propose HanDrawer, a module to condition the hand generation process. Specifically, we apply graph convolutional layers to extract the endogenous spatial structure and physical constraints implicit in MANO hand mesh vertices. We then align and fuse these spatial features with other modalities via cross-attention. The spatially fused features are used to guide a single stage diffusion model denoising process for high quality generation of the hand region. To improve the accuracy of spatial feature fusion, we propose a Position-Preserving Zero Padding (PPZP) fusion strategy, which ensures that the features extracted by HanDrawer are fused into the region of interest in the relevant layers of the diffusion model. HanDrawer learns the entire image features while paying special attention to the hand region thanks to an additional hand reconstruction loss combined with the denoising loss. To accurately train and evaluate our approach, we perform careful cleansing and relabeling of the widely used HaGRID hand gesture dataset and obtain high quality multimodal data. Quantitative and qualitative analyses demonstrate the state-of-the-art performance of our method on the HaGRID dataset through multiple evaluation metrics. Source code and our enhanced dataset will be released publicly if the paper is accepted.

Multimodal Outer Arithmetic Block Dual Fusion of Whole Slide Images and Omics Data for Precision Oncology

Developing a central nervous system (CNS) tumor classifier by integrating DNA methylation data with Whole Slide Images (WSI) offers significant potential for enhancing diagnostic precision in neuropathology. Existing approaches typically integrate encoded omic data with histology only once - either at an early or late fusion stage - while reintroducing encoded omic data to create a dual fusion variant remains unexplored. Nevertheless, reintroduction of omic embeddings during early and late fusion enables the capture of complementary information from localized patch-level and holistic slide-level interactions, allowing boosted performance through advanced multimodal integration. To achieve this, we propose a dual fusion framework that integrates omic data at both early and late stages, fully leveraging its diagnostic strength. In the early fusion stage, omic embeddings are projected into a patch-wise latent space, generating omic-WSI embeddings that encapsulate per-patch molecular and morphological insights, effectively incorporating this information into the spatial representation of histology. These embeddings are refined with a multiple instance learning gated attention mechanism to attend to critical patches. In the late fusion stage, we reintroduce the omic data by fusing it with slide-level omic-WSI embeddings using a Multimodal Outer Arithmetic Block (MOAB), which richly intermingles features from both modalities, capturing their global correlations and complementarity. We demonstrate accurate CNS tumor subtyping across 20 fine-grained subtypes and validate our approach on benchmark datasets, achieving improved survival prediction on TCGA-BLCA and competitive performance on TCGA-BRCA compared to state-of-the-art methods. This dual fusion strategy enhances interpretability and classification performance, highlighting its potential for clinical diagnostics.

Compositional Segmentation of Cardiac Images Leveraging Metadata

Cardiac image segmentation is essential for automated cardiac function assessment and monitoring of changes in cardiac structures over time. Inspired by coarse-to-fine approaches in image analysis, we propose a novel multitask compositional segmentation approach that can simultaneously localize the heart in a cardiac image and perform part-based segmentation of different regions of interest. We demonstrate that this compositional approach achieves better results than direct segmentation of the anatomies. Further, we propose a novel Cross-Modal Feature Integration (CMFI) module to leverage the metadata related to cardiac imaging collected during image acquisition. We perform experiments on two different modalities, MRI and ultrasound, using public datasets, Multi-disease, Multi-View, and Multi-Centre (M&Ms-2) and Multi-structure Ultrasound Segmentation (CAMUS) data, to showcase the efficiency of the proposed compositional segmentation method and Cross-Modal Feature Integration module incorporating metadata within the proposed compositional segmentation network. The source code is available: https://github.com/kabbas570/CompSeg-MetaData.

Going Beyond H&E and Oncology: How Do Histopathology Foundation Models Perform for Multi-stain IHC and Immunology?

This study evaluates the generalisation capabilities of state-of-the-art histopathology foundation models on out-of-distribution multi-stain autoimmune Immunohistochemistry datasets. We compare 13 feature extractor models, including ImageNet-pretrained networks, and histopathology foundation models trained on both public and proprietary data, on Rheumatoid Arthritis subtyping and Sjogren's Disease detection tasks. Using a simple Attention-Based Multiple Instance Learning classifier, we assess the transferability of learned representations from cancer H&E images to autoimmune IHC images. Contrary to expectations, histopathology-pretrained models did not significantly outperform ImageNet-pretrained models. Furthermore, there was evidence of both autoimmune feature misinterpretation and biased feature importance. Our findings highlight the challenges in transferring knowledge from cancer to autoimmune histopathology and emphasise the need for careful evaluation of AI models across diverse histopathological tasks. The code to run this benchmark is available at https://github.com/AmayaGS/ImmunoHistoBench.

A low complexity contextual stacked ensemble-learning approach for pedestrian intent prediction

Walking as a form of active travel is essential in promoting sustainable transport. It is thus crucial to accurately predict pedestrian crossing intention and avoid collisions, especially with the advent of autonomous and advanced driver-assisted vehicles. Current research leverages computer vision and machine learning advances to predict near-misses; however, this often requires high computation power to yield reliable results. In contrast, this work proposes a low-complexity ensemble-learning approach that employs contextual data for predicting the pedestrian's intent for crossing. The pedestrian is first detected, and their image is then compressed using skeleton-ization, and contextual information is added into a stacked ensemble-learning approach. Our experiments on different datasets achieve similar pedestrian intent prediction performance as the state-of-the-art approaches with 99.7% reduction in computational complexity. Our source code and trained models will be released upon paper acceptance

Adaptive Multi-Modal Control of Digital Human Hand Synthesis Using a Region-Aware Cycle Loss

Diffusion models have shown their remarkable ability to synthesize images, including the generation of humans in specific poses. However, current models face challenges in adequately expressing conditional control for detailed hand pose generation, leading to significant distortion in the hand regions. To tackle this problem, we first curate the How2Sign dataset to provide richer and more accurate hand pose annotations. In addition, we introduce adaptive, multi-modal fusion to integrate characters' physical features expressed in different modalities such as skeleton, depth, and surface normal. Furthermore, we propose a novel Region-Aware Cycle Loss (RACL) that enables the diffusion model training to focus on improving the hand region, resulting in improved quality of generated hand gestures. More specifically, the proposed RACL computes a weighted keypoint distance between the full-body pose keypoints from the generated image and the ground truth, to generate higher-quality hand poses while balancing overall pose accuracy. Moreover, we use two hand region metrics, named hand-PSNR and hand-Distance for hand pose generation evaluations. Our experimental evaluations demonstrate the effectiveness of our proposed approach in improving the quality of digital human pose generation using diffusion models, especially the quality of the hand region. The source code is available at https://github.com/fuqifan/Region-Aware-Cycle-Loss.