SyncFix: Fixing 3D Reconstructions via Multi-View Synchronization

We present SyncFix, a framework that enforces cross-view consistency during the diffusion-based refinement of reconstructed scenes. SyncFix formulates refinement as a joint latent bridge matching problem, synchronizing distorted and clean representations across multiple views to fix the semantic and geometric inconsistencies. This means SyncFix learns a joint conditional over multiple views to enforce consistency throughout the denoising trajectory. Our training is done only on image pairs, but it generalizes naturally to an arbitrary number of views during inference. Moreover, reconstruction quality improves with additional views, with diminishing returns at higher view counts. Qualitative and quantitative results demonstrate that SyncFix consistently generates high-quality reconstructions and surpasses current state-of-the-art baselines, even in the absence of clean reference images. SyncFix achieves even higher fidelity when sparse references are available.

Uncertainty-quantified Pulse Signal Recovery from Facial Video using Regularized Stochastic Interpolants

Imaging Photoplethysmography (iPPG), an optical procedure which recovers a human's blood volume pulse (BVP) waveform using pixel readout from a camera, is an exciting research field with many researchers performing clinical studies of iPPG algorithms. While current algorithms to solve the iPPG task have shown outstanding performance on benchmark datasets, no state-of-the art algorithms, to the best of our knowledge, performs test-time sampling of solution space, precluding an uncertainty analysis that is critical for clinical applications. We address this deficiency though a new paradigm named Regularized Interpolants with Stochasticity for iPPG (RIS-iPPG). Modeling iPPG recovery as an inverse problem, we build probability paths that evolve the camera pixel distribution to the ground-truth signal distribution by predicting the instantaneous flow and score vectors of a time-dependent stochastic process; and at test-time, we sample the posterior distribution of the correct BVP waveform given the camera pixel intensity measurements by solving a stochastic differential equation. Given that physiological changes are slowly varying, we show that iPPG recovery can be improved through regularization that maximizes the correlation between the residual flow vector predictions of two adjacent time windows. Experimental results on three datasets show that RIS-iPPG provides superior reconstruction quality and uncertainty estimates of the reconstruction, a critical tool for the widespread adoption of iPPG algorithms in clinical and consumer settings.

Detecting HIV-Related Stigma in Clinical Narratives Using Large Language Models

Human immunodeficiency virus (HIV)-related stigma is a critical psychosocial determinant of health for people living with HIV (PLWH), influencing mental health, engagement in care, and treatment outcomes. Although stigma-related experiences are documented in clinical narratives, there is a lack of off-the-shelf tools to extract and categorize them. This study aims to develop a large language model (LLM)-based tool for identifying HIV stigma from clinical notes. We identified clinical notes from PLWH receiving care at the University of Florida (UF) Health between 2012 and 2022. Candidate sentences were identified using expert-curated stigma-related keywords and iteratively expanded via clinical word embeddings. A total of 1,332 sentences were manually annotated across four stigma subscales: Concern with Public Attitudes, Disclosure Concerns, Negative Self-Image, and Personalized Stigma. We compared GatorTron-large and BERT as encoder-based baselines, and GPT-OSS-20B, LLaMA-8B, and MedGemma-27B as generative LLMs, under zero-shot and few-shot prompting. GatorTron-large achieved the best overall performance (Micro F1 = 0.62). Few-shot prompting substantially improved generative model performance, with 5-shot GPT-OSS-20B and LLaMA-8B achieving Micro-F1 scores of 0.57 and 0.59, respectively. Performance varied by stigma subscale, with Negative Self-Image showing the highest predictability and Personalized Stigma remaining the most challenging. Zero-shot generative inference exhibited non-trivial failure rates (up to 32%). This study develops the first practical NLP tool for identifying HIV stigma in clinical notes.

A Parameter-Efficient Transfer Learning Approach through Multitask Prompt Distillation and Decomposition for Clinical NLP

Existing prompt-based fine-tuning methods typically learn task-specific prompts independently, imposing significant computing and storage overhead at scale when deploying multiple clinical natural language processing (NLP) systems. We present a multitask prompt distillation and decomposition framework that learns a single shared metaprompt from 21 diverse clinical source tasks and adapts it to unseen target tasks with fewer than 0.05% trainable parameters. Evaluated across five clinical NLP task types (named entity recognition, relation extraction, question answering, natural language inference, and summarization) on 10 held-out target datasets using three backbone models (LLaMA 3.1 8B, Meditron3 8B, gpt-oss 20B), our framework consistently outperforms LoRA by 1.5~1.7% despite using orders of magnitude fewer parameters, and exceeds single-task prompt tuning by 6.1~6.6%. The gpt-oss 20B model achieves the highest overall performance, particularly on clinical reasoning tasks. The strong zero- and few-shot performance demonstrates better transferability of the shared prompt representation.

Improving Clinical Trial Recruitment using Clinical Narratives and Large Language Models

Screening patients for enrollment is a well-known, labor-intensive bottleneck that leads to under-enrollment and, ultimately, trial failures. Recent breakthroughs in large language models (LLMs) offer a promising opportunity to use artificial intelligence to improve screening. This study systematically explored both encoder- and decoder-based generative LLMs for screening clinical narratives to facilitate clinical trial recruitment. We examined both general-purpose LLMs and medical-adapted LLMs and explored three strategies to alleviate the "Lost in the Middle" issue when handling long documents, including 1) Original long-context: using the default context windows of LLMs, 2) NER-based extractive summarization: converting the long document into summarizations using named entity recognition, 3) RAG: dynamic evidence retrieval based on eligibility criteria. The 2018 N2C2 Track 1 benchmark dataset is used for evaluation. Our experimental results show that the MedGemma model with the RAG strategy achieved the best micro-F1 score of 89.05%, outperforming other models. Generative LLMs have remarkably improved trial criteria that require long-term reasoning across long documents, whereas trial criteria that span a short piece of context (e.g., lab tests) show incremental improvements. The real-world adoption of LLMs for trial recruitment must consider specific criteria for selecting among rule-based queries, encoder-based LLMs, and generative LLMs to maximize efficiency within reasonable computing costs.

Countering Catastrophic Forgetting of Large Language Models for Better Instruction Following via Weight-Space Model Merging

Large language models have been adopted in the medical domain for clinical documentation to reduce clinician burden. However, studies have reported that LLMs often "forget" a significant amount of instruction-following ability when fine-tuned using a task-specific medical dataset, a critical challenge in adopting general-purpose LLMs for clinical applications. This study presents a model merging framework to efficiently adapt general-purpose LLMs to the medical domain by countering this forgetting issue. By merging a clinical foundation model (GatorTronLlama) with a general instruct model (Llama-3.1-8B-Instruct) via interpolation-based merge methods, we seek to derive a domain-adapted model with strong performance on clinical tasks while retaining instruction-following ability. Comprehensive evaluation across medical benchmarks and five clinical generation tasks (e.g., radiology and discharge summarization) shows that merged models can effectively mitigate catastrophic forgetting, preserve clinical domain expertise, and retain instruction-following ability. In addition, our model merging strategies demonstrate training efficiency, achieving performance on par with fully fine-tuned baselines under severely constrained supervision (e.g., 64-shot vs. 256-shot). Consequently, weight-space merging constitutes a highly scalable solution for adapting open-source LLMs to clinical applications, facilitating broader deployment in resource-constrained healthcare environments.

CAM3R: Camera-Agnostic Model for 3D Reconstruction

Recovering dense 3D geometry from unposed images remains a foundational challenge in computer vision. Current state-of-the-art models are predominantly trained on perspective datasets, which implicitly constrains them to a standard pinhole camera geometry. As a result, these models suffer from significant geometric degradation when applied to wide-angle imagery captured via non-rectilinear optics, such as fisheye or panoramic sensors. To address this, we present CAM3R, a Camera-Agnostic, feed-forward Model for 3D Reconstruction capable of processing images from wide-angle camera models without prior calibration. Our framework consists of a two-view network which is bifurcated into a Ray Module (RM) to estimate per-pixel ray directions and a Cross-view Module (CVM) to infer radial distance with confidence maps, pointmaps, and relative poses. To unify these pairwise predictions into a consistent 3D scene, we introduce a Ray-Aware Global Alignment framework for pose refinement and scale optimization while strictly preserving the predicted local geometry. Extensive experiments on various camera model datasets, including panorama, fisheye and pinhole imagery, demonstrate that CAM3R establishes a new state-of-the-art in pose estimation and reconstruction.

SEHFS: Structural Entropy-Guided High-Order Correlation Learning for Multi-View Multi-Label Feature Selection

In recent years, multi-view multi-label learning (MVML) has attracted extensive attention due to its close alignment to real-world scenarios. Information-theoretic methods have gained prominence for learning nonlinear correlations. However, two key challenges persist: first, features in real-world data commonly exhibit high-order structural correlations, but existing information-theoretic methods struggle to learn such correlations; second, commonly relying on heuristic optimization, information-theoretic methods are prone to converging to local optima. To address these two challenges, we propose a novel method called Structural Entropy Guided High-Order Correlation Learning for Multi-View Multi-Label Feature Selection (SEHFS). The core idea of SEHFS is to convert the feature graph into a structural-entropy-minimizing encoding tree, quantifying the information cost of high-order dependencies and thus learning high-order feature correlations beyond pairwise correlations. Specifically, features exhibiting strong high-order redundancy are grouped into a single cluster within the encoding tree, while inter-cluster feaeture correlations are minimized, thereby eliminating redundancy both within and across clusters. Furthermore, a new framework based on the fusion of information theory and matrix methods is adopted, which learns a shared semantic matrix and view-specific contribution matrices to reconstruct a global view matrix, thereby enhancing the information-theoretic method and balancing the global and local optimization. The ability of structural entropy to learn high-order correlations is theoretically established, and and both experiments on eight datasets from various domains and ablation studies demonstrate that SEHFS achieves superior performance in feature selection.

MedGPT-oss: Training a General-Purpose Vision-Language Model for Biomedicine

Biomedical multimodal assistants have the potential to unify radiology, pathology, and clinical-text reasoning, yet a critical deployment gap remains: top-performing systems are either closed-source or computationally prohibitive, precluding the on-premises deployment required for patient privacy and PHI compliance. We introduce MEDGPT-OSS, an open-weight, 20B-parameter generalist vision-language model designed to facilitate open research in clinical AI. Rather than relying on architectural complexity, MEDGPT-OSS pairs the GPT-oss language backbone with a visual front-end via a optimized, three-stage training curriculum. By progressively domain-adapting these modules through rigorous data curation and long-context multimodal alignment, we demonstrate that a 20B model can bridge the capacity gap. It successfully outperforms larger open medical models on out-of-distribution (OOD) multimodal reasoning and complex text-only clinical tasks. By unifying diverse modalities under a single instruction-following interface, MEDGPT-OSS maintains a parameter-efficient footprint fully compatible with commodity GPUs. We release the complete training recipe, open-weight checkpoints, and a rigorous evaluation harness to serve as a verifiable foundation for privacy-preserving, institution-specific clinical AI research.

Wrivinder: Towards Spatial Intelligence for Geo-locating Ground Images onto Satellite Imagery

Aligning ground-level imagery with geo-registered satellite maps is crucial for mapping, navigation, and situational awareness, yet remains challenging under large viewpoint gaps or when GPS is unreliable. We introduce Wrivinder, a zero-shot, geometry-driven framework that aggregates multiple ground photographs to reconstruct a consistent 3D scene and align it with overhead satellite imagery. Wrivinder combines SfM reconstruction, 3D Gaussian Splatting, semantic grounding, and monocular depth--based metric cues to produce a stable zenith-view rendering that can be directly matched to satellite context for metrically accurate camera geo-localization. To support systematic evaluation of this task, which lacks suitable benchmarks, we also release MC-Sat, a curated dataset linking multi-view ground imagery with geo-registered satellite tiles across diverse outdoor environments. Together, Wrivinder and MC-Sat provide a first comprehensive baseline and testbed for studying geometry-centered cross-view alignment without paired supervision. In zero-shot experiments, Wrivinder achieves sub-30\,m geolocation accuracy across both dense and large-area scenes, highlighting the promise of geometry-based aggregation for robust ground-to-satellite localization.