Towards Computation- and Communication-efficient Computational Pathology

Despite the impressive performance across a wide range of applications, current computational pathology models face significant diagnostic efficiency challenges due to their reliance on high-magnification whole-slide image analysis. This limitation severely compromises their clinical utility, especially in time-sensitive diagnostic scenarios and situations requiring efficient data transfer. To address these issues, we present a novel computation- and communication-efficient framework called Magnification-Aligned Global-Local Transformer (MAGA-GLTrans). Our approach significantly reduces computational time, file transfer requirements, and storage overhead by enabling effective analysis using low-magnification inputs rather than high-magnification ones. The key innovation lies in our proposed magnification alignment (MAGA) mechanism, which employs self-supervised learning to bridge the information gap between low and high magnification levels by effectively aligning their feature representations. Through extensive evaluation across various fundamental CPath tasks, MAGA-GLTrans demonstrates state-of-the-art classification performance while achieving remarkable efficiency gains: up to 10.7 times reduction in computational time and over 20 times reduction in file transfer and storage requirements. Furthermore, we highlight the versatility of our MAGA framework through two significant extensions: (1) its applicability as a feature extractor to enhance the efficiency of any CPath architecture, and (2) its compatibility with existing foundation models and histopathology-specific encoders, enabling them to process low-magnification inputs with minimal information loss. These advancements position MAGA-GLTrans as a particularly promising solution for time-sensitive applications, especially in the context of intraoperative frozen section diagnosis where both accuracy and efficiency are paramount.

DeltaDiff: A Residual-Guided Diffusion Model for Enhanced Image Super-Resolution

Recently, the application of diffusion models in super-resolution tasks has become a popular research direction. Existing work is focused on fully migrating diffusion models to SR tasks. The diffusion model is proposed in the field of image generation, so in order to make the generated results diverse, the diffusion model combines random Gaussian noise and distributed sampling to increase the randomness of the model. However, the essence of super-resolution tasks requires the model to generate high-resolution images with fidelity. Excessive addition of random factors can result in the model generating detailed information that does not belong to the HR image. To address this issue, we propose a new diffusion model called Deltadiff, which uses only residuals between images for diffusion, making the entire diffusion process more stable. The experimental results show that our method surpasses state-of-the-art models and generates results with better fidelity. Our code and model are publicly available at https://github.com/continueyang/DeltaDiff

GVTNet: Graph Vision Transformer For Face Super-Resolution

Recent advances in face super-resolution research have utilized the Transformer architecture. This method processes the input image into a series of small patches. However, because of the strong correlation between different facial components in facial images. When it comes to super-resolution of low-resolution images, existing algorithms cannot handle the relationships between patches well, resulting in distorted facial components in the super-resolution results. To solve the problem, we propose a transformer architecture based on graph neural networks called graph vision transformer network. We treat each patch as a graph node and establish an adjacency matrix based on the information between patches. In this way, the patch only interacts between neighboring patches, further processing the relationship of facial components. Quantitative and visualization experiments have underscored the superiority of our algorithm over state-of-the-art techniques. Through detailed comparisons, we have demonstrated that our algorithm possesses more advanced super-resolution capabilities, particularly in enhancing facial components. The PyTorch code is available at https://github.com/continueyang/GVTNet

GPT-4o System Card

GPT-4o is an autoregressive omni model that accepts as input any combination of text, audio, image, and video, and generates any combination of text, audio, and image outputs. It's trained end-to-end across text, vision, and audio, meaning all inputs and outputs are processed by the same neural network. GPT-4o can respond to audio inputs in as little as 232 milliseconds, with an average of 320 milliseconds, which is similar to human response time in conversation. It matches GPT-4 Turbo performance on text in English and code, with significant improvement on text in non-English languages, while also being much faster and 50\% cheaper in the API. GPT-4o is especially better at vision and audio understanding compared to existing models. In line with our commitment to building AI safely and consistent with our voluntary commitments to the White House, we are sharing the GPT-4o System Card, which includes our Preparedness Framework evaluations. In this System Card, we provide a detailed look at GPT-4o's capabilities, limitations, and safety evaluations across multiple categories, focusing on speech-to-speech while also evaluating text and image capabilities, and measures we've implemented to ensure the model is safe and aligned. We also include third-party assessments on dangerous capabilities, as well as discussion of potential societal impacts of GPT-4o's text and vision capabilities.

Simplifying, Stabilizing and Scaling Continuous-Time Consistency Models

Consistency models (CMs) are a powerful class of diffusion-based generative models optimized for fast sampling. Most existing CMs are trained using discretized timesteps, which introduce additional hyperparameters and are prone to discretization errors. While continuous-time formulations can mitigate these issues, their success has been limited by training instability. To address this, we propose a simplified theoretical framework that unifies previous parameterizations of diffusion models and CMs, identifying the root causes of instability. Based on this analysis, we introduce key improvements in diffusion process parameterization, network architecture, and training objectives. These changes enable us to train continuous-time CMs at an unprecedented scale, reaching 1.5B parameters on ImageNet 512x512. Our proposed training algorithm, using only two sampling steps, achieves FID scores of 2.06 on CIFAR-10, 1.48 on ImageNet 64x64, and 1.88 on ImageNet 512x512, narrowing the gap in FID scores with the best existing diffusion models to within 10%.

Towards Realistic Emotional Voice Conversion using Controllable Emotional Intensity

Realistic emotional voice conversion (EVC) aims to enhance emotional diversity of converted audios, making the synthesized voices more authentic and natural. To this end, we propose Emotional Intensity-aware Network (EINet), dynamically adjusting intonation and rhythm by incorporating controllable emotional intensity. To better capture nuances in emotional intensity, we go beyond mere distance measurements among acoustic features. Instead, an emotion evaluator is utilized to precisely quantify speaker's emotional state. By employing an intensity mapper, intensity pseudo-labels are obtained to bridge the gap between emotional speech intensity modeling and run-time conversion. To ensure high speech quality while retaining controllability, an emotion renderer is used for combining linguistic features smoothly with manipulated emotional features at frame level. Furthermore, we employ a duration predictor to facilitate adaptive prediction of rhythm changes condition on specifying intensity value. Experimental results show EINet's superior performance in naturalness and diversity of emotional expression compared to state-of-the-art EVC methods.

Temporal Label Hierachical Network for Compound Emotion Recognition

The emotion recognition has attracted more attention in recent decades. Although significant progress has been made in the recognition technology of the seven basic emotions, existing methods are still hard to tackle compound emotion recognition that occurred commonly in practical application. This article introduces our achievements in the 7th Field Emotion Behavior Analysis (ABAW) competition. In the competition, we selected pre trained ResNet18 and Transformer, which have been widely validated, as the basic network framework. Considering the continuity of emotions over time, we propose a time pyramid structure network for frame level emotion prediction. Furthermore. At the same time, in order to address the lack of data in composite emotion recognition, we utilized fine-grained labels from the DFEW database to construct training data for emotion categories in competitions. Taking into account the characteristics of valence arousal of various complex emotions, we constructed a classification framework from coarse to fine in the label space.

Energy Model-based Accurate Shapley Value Estimation for Interpretable Deep Learning Predictive Modelling

As a favorable tool for explainable artificial intelligence (XAI), Shapley value has been widely used to interpret deep learning based predictive models. However, accurate and efficient estimation of Shapley value is a difficult task since the computation load grows exponentially with the increase of input features. Most existing accelerated Shapley value estimation methods have to compromise on estimation accuracy with efficiency. In this article, we present EmSHAP(Energy model-based Shapley value estimation), which can effectively approximate the expectation of Shapley contribution function/deep learning model under arbitrary subset of features given the rest. In order to determine the proposal conditional distribution in the energy model, a gated recurrent unit(GRU) is introduced by mapping the input features onto a hidden space, so that the impact of input feature orderings can be eliminated. In addition, a dynamic masking scheme is proposed to improve the generalization ability. It is proved in Theorems 1, 2 and 3 that EmSHAP achieves tighter error bound than state-of-the-art methods like KernelSHAP and VAEAC, leading to higher estimation accuracy. Finally, case studies on a medical application and an industrial application show that the proposed Shapley value-based explainable framework exhibits enhanced estimation accuracy without compromise on efficiency.

PAVITS: Exploring Prosody-aware VITS for End-to-End Emotional Voice Conversion

In this paper, we propose Prosody-aware VITS (PAVITS) for emotional voice conversion (EVC), aiming to achieve two major objectives of EVC: high content naturalness and high emotional naturalness, which are crucial for meeting the demands of human perception. To improve the content naturalness of converted audio, we have developed an end-to-end EVC architecture inspired by the high audio quality of VITS. By seamlessly integrating an acoustic converter and vocoder, we effectively address the common issue of mismatch between emotional prosody training and run-time conversion that is prevalent in existing EVC models. To further enhance the emotional naturalness, we introduce an emotion descriptor to model the subtle prosody variations of different speech emotions. Additionally, we propose a prosody predictor, which predicts prosody features from text based on the provided emotion label. Notably, we introduce a prosody alignment loss to establish a connection between latent prosody features from two distinct modalities, ensuring effective training. Experimental results show that the performance of PAVITS is superior to the state-of-the-art EVC methods. Speech Samples are available at https://jeremychee4.github.io/pavits4EVC/ .

Towards Efficient and Exact Optimization of Language Model Alignment

The alignment of language models with human preferences is vital for their application in real-world tasks. The problem is formulated as optimizing the model's policy to maximize the expected reward that reflects human preferences with minimal deviation from the initial policy. While considered as a straightforward solution, reinforcement learning (RL) suffers from high variance in policy updates, which impedes efficient policy improvement. Recently, direct preference optimization (DPO) was proposed to directly optimize the policy from preference data. Though simple to implement, DPO is derived based on the optimal policy that is not assured to be achieved in practice, which undermines its convergence to the intended solution. In this paper, we propose efficient exact optimization (EXO) of the alignment objective. We prove that EXO is guaranteed to optimize in the same direction as the RL algorithms asymptotically for arbitary parametrization of the policy, while enables efficient optimization by circumventing the complexities associated with RL algorithms. We compare our method to DPO with both theoretical and empirical analyses, and further demonstrate the advantages of our method over existing approaches on realistic human preference data.