A Value Mapping Virtual Staining Framework for Large-scale Histological Imaging

The emergence of virtual staining technology provides a rapid and efficient alternative for researchers in tissue pathology. It enables the utilization of unlabeled microscopic samples to generate virtual replicas of chemically stained histological slices, or facilitate the transformation of one staining type into another. The remarkable performance of generative networks, such as CycleGAN, offers an unsupervised learning approach for virtual coloring, overcoming the limitations of high-quality paired data required in supervised learning. Nevertheless, large-scale color transformation necessitates processing large field-of-view images in patches, often resulting in significant boundary inconsistency and artifacts. Additionally, the transformation between different colorized modalities typically needs further efforts to modify loss functions and tune hyperparameters for independent training of networks. In this study, we introduce a general virtual staining framework that is adaptable to various conditions. We propose a loss function based on the value mapping constraint to ensure the accuracy of virtual coloring between different pathological modalities, termed the Value Mapping Generative Adversarial Network (VM-GAN). Meanwhile, we present a confidence-based tiling method to address the challenge of boundary inconsistency arising from patch-wise processing. Experimental results on diverse data with varying staining protocols demonstrate that our method achieves superior quantitative indicators and improved visual perception.

Adaptive Rate Control for Deep Video Compression with Rate-Distortion Prediction

Deep video compression has made significant progress in recent years, achieving rate-distortion performance that surpasses that of traditional video compression methods. However, rate control schemes tailored for deep video compression have not been well studied. In this paper, we propose a neural network-based $\lambda$-domain rate control scheme for deep video compression, which determines the coding parameter $\lambda$ for each to-be-coded frame based on the rate-distortion-$\lambda$ (R-D-$\lambda$) relationships directly learned from uncompressed frames, achieving high rate control accuracy efficiently without the need for pre-encoding. Moreover, this content-aware scheme is able to mitigate inter-frame quality fluctuations and adapt to abrupt changes in video content. Specifically, we introduce two neural network-based predictors to estimate the relationship between bitrate and $\lambda$, as well as the relationship between distortion and $\lambda$ for each frame. Then we determine the coding parameter $\lambda$ for each frame to achieve the target bitrate. Experimental results demonstrate that our approach achieves high rate control accuracy at the mini-GOP level with low time overhead and mitigates inter-frame quality fluctuations across video content of varying resolutions.

High-Efficiency Neural Video Compression via Hierarchical Predictive Learning

The enhanced Deep Hierarchical Video Compression-DHVC 2.0-has been introduced. This single-model neural video codec operates across a broad range of bitrates, delivering not only superior compression performance to representative methods but also impressive complexity efficiency, enabling real-time processing with a significantly smaller memory footprint on standard GPUs. These remarkable advancements stem from the use of hierarchical predictive coding. Each video frame is uniformly transformed into multiscale representations through hierarchical variational autoencoders. For a specific scale's feature representation of a frame, its corresponding latent residual variables are generated by referencing lower-scale spatial features from the same frame and then conditionally entropy-encoded using a probabilistic model whose parameters are predicted using same-scale temporal reference from previous frames and lower-scale spatial reference of the current frame. This feature-space processing operates from the lowest to the highest scale of each frame, completely eliminating the need for the complexity-intensive motion estimation and compensation techniques that have been standard in video codecs for decades. The hierarchical approach facilitates parallel processing, accelerating both encoding and decoding, and supports transmission-friendly progressive decoding, making it particularly advantageous for networked video applications in the presence of packet loss. Source codes will be made available.

All-in-One Image Coding for Joint Human-Machine Vision with Multi-Path Aggregation

Image coding for multi-task applications, catering to both human perception and machine vision, has been extensively investigated. Existing methods often rely on multiple task-specific encoder-decoder pairs, leading to high overhead of parameter and bitrate usage, or face challenges in multi-objective optimization under a unified representation, failing to achieve both performance and efficiency. To this end, we propose Multi-Path Aggregation (MPA) integrated into existing coding models for joint human-machine vision, unifying the feature representation with an all-in-one architecture. MPA employs a predictor to allocate latent features among task-specific paths based on feature importance varied across tasks, maximizing the utility of shared features while preserving task-specific features for subsequent refinement. Leveraging feature correlations, we develop a two-stage optimization strategy to alleviate multi-task performance degradation. Upon the reuse of shared features, as low as 1.89% parameters are further augmented and fine-tuned for a specific task, which completely avoids extensive optimization of the entire model. Experimental results show that MPA achieves performance comparable to state-of-the-art methods in both task-specific and multi-objective optimization across human viewing and machine analysis tasks. Moreover, our all-in-one design supports seamless transitions between human- and machine-oriented reconstruction, enabling task-controllable interpretation without altering the unified model. Code is available at https://github.com/NJUVISION/MPA.

Accelerating block-level rate control for learned image compression

Despite the unprecedented compression efficiency achieved by deep learned image compression (LIC), existing methods usually approximate the desired bitrate by adjusting a single quality factor for a given input image, which may compromise the rate control results. Considering the Rate-Distortion (R - D) characteristics of different spatial content, this work introduces the block-level rate control based on a novel D - {\lambda} model specific for LIC. Furthermore, we try to exploit the inter-block correlations and propose a block-wise R - D prediction algorithm which greatly speeds up block-level rate control while still guaranteeing high accuracy. Experimental results show that the proposed rate control achieves up to 100 times, speed-up with more than 98% accuracy. Our approach provides an optimal bit allocation for each block and therefore improves the overall compression performance, which offers great potential for block-level LIC.

EmoTalk3D: High-Fidelity Free-View Synthesis of Emotional 3D Talking Head

We present a novel approach for synthesizing 3D talking heads with controllable emotion, featuring enhanced lip synchronization and rendering quality. Despite significant progress in the field, prior methods still suffer from multi-view consistency and a lack of emotional expressiveness. To address these issues, we collect EmoTalk3D dataset with calibrated multi-view videos, emotional annotations, and per-frame 3D geometry. By training on the EmoTalk3D dataset, we propose a \textit{`Speech-to-Geometry-to-Appearance'} mapping framework that first predicts faithful 3D geometry sequence from the audio features, then the appearance of a 3D talking head represented by 4D Gaussians is synthesized from the predicted geometry. The appearance is further disentangled into canonical and dynamic Gaussians, learned from multi-view videos, and fused to render free-view talking head animation. Moreover, our model enables controllable emotion in the generated talking heads and can be rendered in wide-range views. Our method exhibits improved rendering quality and stability in lip motion generation while capturing dynamic facial details such as wrinkles and subtle expressions. Experiments demonstrate the effectiveness of our approach in generating high-fidelity and emotion-controllable 3D talking heads. The code and EmoTalk3D dataset are released at https://nju-3dv.github.io/projects/EmoTalk3D.

HINER: Neural Representation for Hyperspectral Image

This paper introduces {HINER}, a novel neural representation for compressing HSI and ensuring high-quality downstream tasks on compressed HSI. HINER fully exploits inter-spectral correlations by explicitly encoding of spectral wavelengths and achieves a compact representation of the input HSI sample through joint optimization with a learnable decoder. By additionally incorporating the Content Angle Mapper with the L1 loss, we can supervise the global and local information within each spectral band, thereby enhancing the overall reconstruction quality. For downstream classification on compressed HSI, we theoretically demonstrate the task accuracy is not only related to the classification loss but also to the reconstruction fidelity through a first-order expansion of the accuracy degradation, and accordingly adapt the reconstruction by introducing Adaptive Spectral Weighting. Owing to the monotonic mapping of HINER between wavelengths and spectral bands, we propose Implicit Spectral Interpolation for data augmentation by adding random variables to input wavelengths during classification model training. Experimental results on various HSI datasets demonstrate the superior compression performance of our HINER compared to the existing learned methods and also the traditional codecs. Our model is lightweight and computationally efficient, which maintains high accuracy for downstream classification task even on decoded HSIs at high compression ratios. Our materials will be released at https://github.com/Eric-qi/HINER.

FINER++: Building a Family of Variable-periodic Functions for Activating Implicit Neural Representation

Implicit Neural Representation (INR), which utilizes a neural network to map coordinate inputs to corresponding attributes, is causing a revolution in the field of signal processing. However, current INR techniques suffer from the "frequency"-specified spectral bias and capacity-convergence gap, resulting in imperfect performance when representing complex signals with multiple "frequencies". We have identified that both of these two characteristics could be handled by increasing the utilization of definition domain in current activation functions, for which we propose the FINER++ framework by extending existing periodic/non-periodic activation functions to variable-periodic ones. By initializing the bias of the neural network with different ranges, sub-functions with various frequencies in the variable-periodic function are selected for activation. Consequently, the supported frequency set can be flexibly tuned, leading to improved performance in signal representation. We demonstrate the generalization and capabilities of FINER++ with different activation function backbones (Sine, Gauss. and Wavelet) and various tasks (2D image fitting, 3D signed distance field representation, 5D neural radiance fields optimization and streamable INR transmission), and we show that it improves existing INRs. Project page: {https://liuzhen0212.github.io/finerpp/}

Neural Poisson Solver: A Universal and Continuous Framework for Natural Signal Blending

Implicit Neural Representation (INR) has become a popular method for representing visual signals (e.g., 2D images and 3D scenes), demonstrating promising results in various downstream applications. Given its potential as a medium for visual signals, exploring the development of a neural blending method that utilizes INRs is a natural progression. Neural blending involves merging two INRs to create a new INR that encapsulates information from both original representations. A direct approach involves applying traditional image editing methods to the INR rendering process. However, this method often results in blending distortions, artifacts, and color shifts, primarily due to the discretization of the underlying pixel grid and the introduction of boundary conditions for solving variational problems. To tackle this issue, we introduce the Neural Poisson Solver, a plug-and-play and universally applicable framework across different signal dimensions for blending visual signals represented by INRs. Our Neural Poisson Solver offers a variational problem-solving approach based on the continuous Poisson equation, demonstrating exceptional performance across various domains. Specifically, we propose a gradient-guided neural solver to represent the solution process of the variational problem, refining the target signal to achieve natural blending results. We also develop a Poisson equation-based loss and optimization scheme to train our solver, ensuring it effectively blends the input INR scenes while preserving their inherent structure and semantic content. The lack of dependence on additional prior knowledge makes our method easily adaptable to various task categories, highlighting its versatility. Comprehensive experimental results validate the robustness of our approach across multiple dimensions and blending tasks.

PNeRV: Enhancing Spatial Consistency via Pyramidal Neural Representation for Videos

The primary focus of Neural Representation for Videos (NeRV) is to effectively model its spatiotemporal consistency. However, current NeRV systems often face a significant issue of spatial inconsistency, leading to decreased perceptual quality. To address this issue, we introduce the Pyramidal Neural Representation for Videos (PNeRV), which is built on a multi-scale information connection and comprises a lightweight rescaling operator, Kronecker Fully-connected layer (KFc), and a Benign Selective Memory (BSM) mechanism. The KFc, inspired by the tensor decomposition of the vanilla Fully-connected layer, facilitates low-cost rescaling and global correlation modeling. BSM merges high-level features with granular ones adaptively. Furthermore, we provide an analysis based on the Universal Approximation Theory of the NeRV system and validate the effectiveness of the proposed PNeRV.We conducted comprehensive experiments to demonstrate that PNeRV surpasses the performance of contemporary NeRV models, achieving the best results in video regression on UVG and DAVIS under various metrics (PSNR, SSIM, LPIPS, and FVD). Compared to vanilla NeRV, PNeRV achieves a +4.49 dB gain in PSNR and a 231% increase in FVD on UVG, along with a +3.28 dB PSNR and 634% FVD increase on DAVIS.