SouLLMate: An Application Enhancing Diverse Mental Health Support with Adaptive LLMs, Prompt Engineering, and RAG Techniques

Mental health issues significantly impact individuals' daily lives, yet many do not receive the help they need even with available online resources. This study aims to provide diverse, accessible, stigma-free, personalized, and real-time mental health support through cutting-edge AI technologies. It makes the following contributions: (1) Conducting an extensive survey of recent mental health support methods to identify prevalent functionalities and unmet needs. (2) Introducing SouLLMate, an adaptive LLM-driven system that integrates LLM technologies, Chain, Retrieval-Augmented Generation (RAG), prompt engineering, and domain knowledge. This system offers advanced features such as Risk Detection and Proactive Guidance Dialogue, and utilizes RAG for personalized profile uploads and Conversational Information Extraction. (3) Developing novel evaluation approaches for preliminary assessments and risk detection via professionally annotated interview data and real-life suicide tendency data. (4) Proposing the Key Indicator Summarization (KIS), Proactive Questioning Strategy (PQS), and Stacked Multi-Model Reasoning (SMMR) methods to enhance model performance and usability through context-sensitive response adjustments, semantic coherence evaluations, and enhanced accuracy of long-context reasoning in language models. This study contributes to advancing mental health support technologies, potentially improving the accessibility and effectiveness of mental health care globally.

Automatic Identification of Driving Maneuver Patterns using a Robust Hidden Semi-Markov Models

There is an increase in interest to model driving maneuver patterns via the automatic unsupervised clustering of naturalistic sequential kinematic driving data. The patterns learned are often used in transportation research areas such as eco-driving, road safety, and intelligent vehicles. One such model capable of modeling these patterns is the Hierarchical Dirichlet Process Hidden Semi-Markov Model (HDP-HSMM), as it is often used to estimate data segmentation, state duration, and transition probabilities. While this model is a powerful tool for automatically clustering observed sequential data, the existing HDP-HSMM estimation suffers from an inherent tendency to overestimate the number of states. This can result in poor estimation, which can potentially impact impact transportation research through incorrect inference of driving patterns. In this paper, a new robust HDP-HSMM (rHDP-HSMM) method is proposed to reduce the number of redundant states and improve the consistency of the model's estimation. Both a simulation study and a case study using naturalistic driving data are presented to demonstrate the effectiveness of the proposed rHDP-HSMM in identifying and inference of driving maneuver patterns.

SEE-OoD: Supervised Exploration For Enhanced Out-of-Distribution Detection

Current techniques for Out-of-Distribution (OoD) detection predominantly rely on quantifying predictive uncertainty and incorporating model regularization during the training phase, using either real or synthetic OoD samples. However, methods that utilize real OoD samples lack exploration and are prone to overfit the OoD samples at hand. Whereas synthetic samples are often generated based on features extracted from training data, rendering them less effective when the training and OoD data are highly overlapped in the feature space. In this work, we propose a Wasserstein-score-based generative adversarial training scheme to enhance OoD detection accuracy, which, for the first time, performs data augmentation and exploration simultaneously under the supervision of limited OoD samples. Specifically, the generator explores OoD spaces and generates synthetic OoD samples using feedback from the discriminator, while the discriminator exploits both the observed and synthesized samples for OoD detection using a predefined Wasserstein score. We provide theoretical guarantees that the optimal solutions of our generative scheme are statistically achievable through adversarial training in empirical settings. We then demonstrate that the proposed method outperforms state-of-the-art techniques on various computer vision datasets and exhibits superior generalizability to unseen OoD data.

Efficient Subgraph Isomorphism using Graph Topology

Subgraph isomorphism or subgraph matching is generally considered as an NP-complete problem, made more complex in practical applications where the edge weights take real values and are subject to measurement noise and possible anomalies. To the best of our knowledge, almost all subgraph matching methods utilize node labels to perform node-node matching. In the absence of such labels (in applications such as image matching and map matching among others), these subgraph matching methods do not work. We propose a method for identifying the node correspondence between a subgraph and a full graph in the inexact case without node labels in two steps - (a) extract the minimal unique topology preserving subset from the subgraph and find its feasible matching in the full graph, and (b) implement a consensus-based algorithm to expand the matched node set by pairing unique paths based on boundary commutativity. Going beyond the existing subgraph matching approaches, the proposed method is shown to have realistically sub-linear computational efficiency, robustness to random measurement noise, and good statistical properties. Our method is also readily applicable to the exact matching case without loss of generality. To demonstrate the effectiveness of the proposed method, a simulation and a case study is performed on the Erdos-Renyi random graphs and the image-based affine covariant features dataset respectively.

Graph-theoretical approach to robust 3D normal extraction of LiDAR data

Low dimensional primitive feature extraction from LiDAR point clouds (such as planes) forms the basis of majority of LiDAR data processing tasks. A major challenge in LiDAR data analysis arises from the irregular nature of LiDAR data that forces practitioners to either regularize the data using some form of gridding or utilize a triangular mesh such as triangulated irregular network (TIN). While there have been a handful applications using LiDAR data as a connected graph, a principled treatment of utilizing graph-theoretical approach for LiDAR data modelling is still lacking. In this paper, we try to bridge this gap by utilizing graphical approach for normal estimation from LiDAR point clouds. We formulate the normal estimation problem in an optimization framework, where we find the corresponding normal vector for each LiDAR point by utilizing its nearest neighbors and simultaneously enforcing a graph smoothness assumption based on point samples. This is a non-linear constrained convex optimization problem which can then be solved using projected conjugate gradient descent to yield an unique solution. As an enhancement to our optimization problem, we also provide different weighted solutions based on the dot product of the normals and Euclidean distance between the points. In order to assess the performance of our proposed normal extraction method and weighting strategies, we first provide a detailed analysis on repeated randomly generated datasets with four different noise levels and four different tuning parameters. Finally, we benchmark our proposed method against existing state-of-the-art approaches on a large scale synthetic plane extraction dataset. The code for the proposed approach along with the simulations and benchmarking is available at https://github.com/arpan-kusari/graph-plane-extraction-simulation.

A Continual Learning Framework for Adaptive Defect Classification and Inspection

Machine-vision-based defect classification techniques have been widely adopted for automatic quality inspection in manufacturing processes. This article describes a general framework for classifying defects from high volume data batches with efficient inspection of unlabelled samples. The concept is to construct a detector to identify new defect types, send them to the inspection station for labelling, and dynamically update the classifier in an efficient manner that reduces both storage and computational needs imposed by data samples of previously observed batches. Both a simulation study on image classification and a case study on surface defect detection via 3D point clouds are performed to demonstrate the effectiveness of the proposed method.

Precision Radiotherapy via Information Integration of Expert Human Knowledge and AI Recommendation to Optimize Clinical Decision Making

In the precision medicine era, there is a growing need for precision radiotherapy where the planned radiation dose needs to be optimally determined by considering a myriad of patient-specific information in order to ensure treatment efficacy. Existing artificial-intelligence (AI) methods can recommend radiation dose prescriptions within the scope of this available information. However, treating physicians may not fully entrust the AI's recommended prescriptions due to known limitations or when the AI recommendation may go beyond physicians' current knowledge. This paper lays out a systematic method to integrate expert human knowledge with AI recommendations for optimizing clinical decision making. Towards this goal, Gaussian process (GP) models are integrated with deep neural networks (DNNs) to quantify the uncertainty of the treatment outcomes given by physicians and AI recommendations, respectively, which are further used as a guideline to educate clinical physicians and improve AI models performance. The proposed method is demonstrated in a comprehensive dataset where patient-specific information and treatment outcomes are prospectively collected during radiotherapy of $67$ non-small cell lung cancer patients and retrospectively analyzed.

ASC-Net: Unsupervised Medical Anomaly Segmentation Using an Adversarial-based Selective Cutting Network

In this paper we consider the problem of unsupervised anomaly segmentation in medical images, which has attracted increasing attention in recent years due to the expensive pixel-level annotations from experts and the existence of a large amount of unannotated normal and abnormal image scans. We introduce a segmentation network that utilizes adversarial learning to partition an image into two cuts, with one of them falling into a reference distribution provided by the user. This Adversarial-based Selective Cutting network (ASC-Net) bridges the two domains of cluster-based deep segmentation and adversarial-based anomaly/novelty detection algorithms. Our ASC-Net learns from normal and abnormal medical scans to segment anomalies in medical scans without any masks for supervision. We evaluate this unsupervised anomly segmentation model on three public datasets, i.e., BraTS 2019 for brain tumor segmentation, LiTS for liver lesion segmentation, and MS-SEG 2015 for brain lesion segmentation, and also on a private dataset for brain tumor segmentation. Compared to existing methods, our model demonstrates tremendous performance gains in unsupervised anomaly segmentation tasks. Although there is still room to further improve performance compared to supervised learning algorithms, the promising experimental results and interesting observations shed light on building an unsupervised learning algorithm for medical anomaly identification using user-defined knowledge.

WOOD: Wasserstein-based Out-of-Distribution Detection

The training and test data for deep-neural-network-based classifiers are usually assumed to be sampled from the same distribution. When part of the test samples are drawn from a distribution that is sufficiently far away from that of the training samples (a.k.a. out-of-distribution (OOD) samples), the trained neural network has a tendency to make high confidence predictions for these OOD samples. Detection of the OOD samples is critical when training a neural network used for image classification, object detection, etc. It can enhance the classifier's robustness to irrelevant inputs, and improve the system resilience and security under different forms of attacks. Detection of OOD samples has three main challenges: (i) the proposed OOD detection method should be compatible with various architectures of classifiers (e.g., DenseNet, ResNet), without significantly increasing the model complexity and requirements on computational resources; (ii) the OOD samples may come from multiple distributions, whose class labels are commonly unavailable; (iii) a score function needs to be defined to effectively separate OOD samples from in-distribution (InD) samples. To overcome these challenges, we propose a Wasserstein-based out-of-distribution detection (WOOD) method. The basic idea is to define a Wasserstein-distance-based score that evaluates the dissimilarity between a test sample and the distribution of InD samples. An optimization problem is then formulated and solved based on the proposed score function. The statistical learning bound of the proposed method is investigated to guarantee that the loss value achieved by the empirical optimizer approximates the global optimum. The comparison study results demonstrate that the proposed WOOD consistently outperforms other existing OOD detection methods.