SouLLMate: An Application Enhancing Diverse Mental Health Support with Adaptive LLMs, Prompt Engineering, and RAG Techniques

Mental health issues significantly impact individuals' daily lives, yet many do not receive the help they need even with available online resources. This study aims to provide diverse, accessible, stigma-free, personalized, and real-time mental health support through cutting-edge AI technologies. It makes the following contributions: (1) Conducting an extensive survey of recent mental health support methods to identify prevalent functionalities and unmet needs. (2) Introducing SouLLMate, an adaptive LLM-driven system that integrates LLM technologies, Chain, Retrieval-Augmented Generation (RAG), prompt engineering, and domain knowledge. This system offers advanced features such as Risk Detection and Proactive Guidance Dialogue, and utilizes RAG for personalized profile uploads and Conversational Information Extraction. (3) Developing novel evaluation approaches for preliminary assessments and risk detection via professionally annotated interview data and real-life suicide tendency data. (4) Proposing the Key Indicator Summarization (KIS), Proactive Questioning Strategy (PQS), and Stacked Multi-Model Reasoning (SMMR) methods to enhance model performance and usability through context-sensitive response adjustments, semantic coherence evaluations, and enhanced accuracy of long-context reasoning in language models. This study contributes to advancing mental health support technologies, potentially improving the accessibility and effectiveness of mental health care globally.

Advancing Mental Health Pre-Screening: A New Custom GPT for Psychological Distress Assessment

This study introduces 'Psycho Analyst', a custom GPT model based on OpenAI's GPT-4, optimized for pre-screening mental health disorders. Enhanced with DSM-5, PHQ-8, detailed data descriptions, and extensive training data, the model adeptly decodes nuanced linguistic indicators of mental health disorders. It utilizes a dual-task framework that includes binary classification and a three-stage PHQ-8 score computation involving initial assessment, detailed breakdown, and independent assessment, showcasing refined analytic capabilities. Validation with the DAIC-WOZ dataset reveals F1 and Macro-F1 scores of 0.929 and 0.949, respectively, along with the lowest MAE and RMSE of 2.89 and 3.69 in PHQ-8 scoring. These results highlight the model's precision and transformative potential in enhancing public mental health support, improving accessibility, cost-effectiveness, and serving as a second opinion for professionals.

Salience Biased Loss for Object Detection in Aerial Images

Object detection in remote sensing, especially in aerial images, remains a challenging problem due to low image resolution, complex backgrounds, and variation of scale and angles of objects in images. In current implementations, multi-scale based and angle-based networks have been proposed and generate promising results with aerial image detection. In this paper, we propose a novel loss function, called Salience Biased Loss (SBL), for deep neural networks, which uses salience information of the input image to achieve improved performance for object detection. Our novel loss function treats training examples differently based on input complexity in order to avoid the over-contribution of easy cases in the training process. In our experiments, RetinaNet was trained with SBL to generate an one-stage detector, SBL-RetinaNet. SBL-RetinaNet is applied to the largest existing public aerial image dataset, DOTA. Experimental results show our proposed loss function with the RetinaNet architecture outperformed other state-of-art object detection models by at least 4.31 mAP, and RetinaNet by 2.26 mAP with the same inference speed of RetinaNet.

MUFold-SS: Protein Secondary Structure Prediction Using Deep Inception-Inside-Inception Networks

Motivation: Protein secondary structure prediction can provide important information for protein 3D structure prediction and protein functions. Deep learning, which has been successfully applied to various research fields such as image classification and voice recognition, provides a new opportunity to significantly improve the secondary structure prediction accuracy. Although several deep-learning methods have been developed for secondary structure prediction, there is room for improvement. MUFold-SS was developed to address these issues. Results: Here, a very deep neural network, the deep inception-inside-inception networks (Deep3I), is proposed for protein secondary structure prediction and a software tool was implemented using this network. This network takes two inputs: a protein sequence and a profile generated by PSI-BLAST. The output is the predicted eight states (Q8) or three states (Q3) of secondary structures. The proposed Deep3I not only achieves the state-of-the-art performance but also runs faster than other tools. Deep3I achieves Q3 82.8% and Q8 71.1% accuracies on the CB513 benchmark.