Gland segmentation via dual encoders and boundary-enhanced attention

Accurate and automated gland segmentation on pathological images can assist pathologists in diagnosing the malignancy of colorectal adenocarcinoma. However, due to various gland shapes, severe deformation of malignant glands, and overlapping adhesions between glands. Gland segmentation has always been very challenging. To address these problems, we propose a DEA model. This model consists of two branches: the backbone encoding and decoding network and the local semantic extraction network. The backbone encoding and decoding network extracts advanced Semantic features, uses the proposed feature decoder to restore feature space information, and then enhances the boundary features of the gland through boundary enhancement attention. The local semantic extraction network uses the pre-trained DeepLabv3+ as a Local semantic-guided encoder to realize the extraction of edge features. Experimental results on two public datasets, GlaS and CRAG, confirm that the performance of our method is better than other gland segmentation methods.

A novel dataset and a two-stage mitosis nuclei detection method based on hybrid anchor branch

Mitosis detection is one of the challenging problems in computational pathology, and mitotic count is an important index of cancer grading for pathologists. However, current counts of mitotic nuclei rely on pathologists looking microscopically at the number of mitotic nuclei in hot spots, which is subjective and time-consuming. In this paper, we propose a two-stage cascaded network, named FoCasNet, for mitosis detection. In the first stage, a detection network named M_det is proposed to detect as many mitoses as possible. In the second stage, a classification network M_class is proposed to refine the results of the first stage. In addition, the attention mechanism, normalization method, and hybrid anchor branch classification subnet are introduced to improve the overall detection performance. Our method achieves the current highest F1-score of 0.888 on the public dataset ICPR 2012. We also evaluated our method on the GZMH dataset released by our research team for the first time and reached the highest F1-score of 0.563, which is also better than multiple classic detection networks widely used at present. It confirmed the effectiveness and generalization of our method. The code will be available at: https://github.com/antifen/mitosis-nuclei-detection.

A Novel Dataset and a Deep Learning Method for Mitosis Nuclei Segmentation and Classification

Mitosis nuclei count is one of the important indicators for the pathological diagnosis of breast cancer. The manual annotation needs experienced pathologists, which is very time-consuming and inefficient. With the development of deep learning methods, some models with good performance have emerged, but the generalization ability should be further strengthened. In this paper, we propose a two-stage mitosis segmentation and classification method, named SCMitosis. Firstly, the segmentation performance with a high recall rate is achieved by the proposed depthwise separable convolution residual block and channel-spatial attention gate. Then, a classification network is cascaded to further improve the detection performance of mitosis nuclei. The proposed model is verified on the ICPR 2012 dataset, and the highest F-score value of 0.8687 is obtained compared with the current state-of-the-art algorithms. In addition, the model also achieves good performance on GZMH dataset, which is prepared by our group and will be firstly released with the publication of this paper. The code will be available at: https://github.com/antifen/mitosis-nuclei-segmentation.

Binary Representation via Jointly Personalized Sparse Hashing

Unsupervised hashing has attracted much attention for binary representation learning due to the requirement of economical storage and efficiency of binary codes. It aims to encode high-dimensional features in the Hamming space with similarity preservation between instances. However, most existing methods learn hash functions in manifold-based approaches. Those methods capture the local geometric structures (i.e., pairwise relationships) of data, and lack satisfactory performance in dealing with real-world scenarios that produce similar features (e.g. color and shape) with different semantic information. To address this challenge, in this work, we propose an effective unsupervised method, namely Jointly Personalized Sparse Hashing (JPSH), for binary representation learning. To be specific, firstly, we propose a novel personalized hashing module, i.e., Personalized Sparse Hashing (PSH). Different personalized subspaces are constructed to reflect category-specific attributes for different clusters, adaptively mapping instances within the same cluster to the same Hamming space. In addition, we deploy sparse constraints for different personalized subspaces to select important features. We also collect the strengths of the other clusters to build the PSH module with avoiding over-fitting. Then, to simultaneously preserve semantic and pairwise similarities in our JPSH, we incorporate the PSH and manifold-based hash learning into the seamless formulation. As such, JPSH not only distinguishes the instances from different clusters, but also preserves local neighborhood structures within the cluster. Finally, an alternating optimization algorithm is adopted to iteratively capture analytical solutions of the JPSH model. Extensive experiments on four benchmark datasets verify that the JPSH outperforms several hashing algorithms on the similarity search task.

AIM 2020 Challenge on Efficient Super-Resolution: Methods and Results

This paper reviews the AIM 2020 challenge on efficient single image super-resolution with focus on the proposed solutions and results. The challenge task was to super-resolve an input image with a magnification factor x4 based on a set of prior examples of low and corresponding high resolution images. The goal is to devise a network that reduces one or several aspects such as runtime, parameter count, FLOPs, activations, and memory consumption while at least maintaining PSNR of MSRResNet. The track had 150 registered participants, and 25 teams submitted the final results. They gauge the state-of-the-art in efficient single image super-resolution.