Hierarchical Divide-and-Conquer for Fine-Grained Alignment in LLM-Based Medical Evaluation

In the rapidly evolving landscape of large language models (LLMs) for medical applications, ensuring the reliability and accuracy of these models in clinical settings is paramount. Existing benchmarks often focus on fixed-format tasks like multiple-choice QA, which fail to capture the complexity of real-world clinical diagnostics. Moreover, traditional evaluation metrics and LLM-based evaluators struggle with misalignment, often providing oversimplified assessments that do not adequately reflect human judgment. To address these challenges, we introduce HDCEval, a Hierarchical Divide-and-Conquer Evaluation framework tailored for fine-grained alignment in medical evaluation. HDCEval is built on a set of fine-grained medical evaluation guidelines developed in collaboration with professional doctors, encompassing Patient Question Relevance, Medical Knowledge Correctness, and Expression. The framework decomposes complex evaluation tasks into specialized subtasks, each evaluated by expert models trained through Attribute-Driven Token Optimization (ADTO) on a meticulously curated preference dataset. This hierarchical approach ensures that each aspect of the evaluation is handled with expert precision, leading to a significant improvement in alignment with human evaluators.

NLSR: Neuron-Level Safety Realignment of Large Language Models Against Harmful Fine-Tuning

The emergence of finetuning-as-a-service has revealed a new vulnerability in large language models (LLMs). A mere handful of malicious data uploaded by users can subtly manipulate the finetuning process, resulting in an alignment-broken model. Existing methods to counteract fine-tuning attacks typically require substantial computational resources. Even with parameter-efficient techniques like LoRA, gradient updates remain essential. To address these challenges, we propose \textbf{N}euron-\textbf{L}evel \textbf{S}afety \textbf{R}ealignment (\textbf{NLSR}), a training-free framework that restores the safety of LLMs based on the similarity difference of safety-critical neurons before and after fine-tuning. The core of our framework is first to construct a safety reference model from an initially aligned model to amplify safety-related features in neurons. We then utilize this reference model to identify safety-critical neurons, which we prepare as patches. Finally, we selectively restore only those neurons that exhibit significant similarity differences by transplanting these prepared patches, thereby minimally altering the fine-tuned model. Extensive experiments demonstrate significant safety enhancements in fine-tuned models across multiple downstream tasks, while greatly maintaining task-level accuracy. Our findings suggest regions of some safety-critical neurons show noticeable differences after fine-tuning, which can be effectively corrected by transplanting neurons from the reference model without requiring additional training. The code will be available at \url{https://github.com/xinykou/NLSR}

ACE-$M^3$: Automatic Capability Evaluator for Multimodal Medical Models

As multimodal large language models (MLLMs) gain prominence in the medical field, the need for precise evaluation methods to assess their effectiveness has become critical. While benchmarks provide a reliable means to evaluate the capabilities of MLLMs, traditional metrics like ROUGE and BLEU employed for open domain evaluation only focus on token overlap and may not align with human judgment. Although human evaluation is more reliable, it is labor-intensive, costly, and not scalable. LLM-based evaluation methods have proven promising, but to date, there is still an urgent need for open-source multimodal LLM-based evaluators in the medical field. To address this issue, we introduce ACE-$M^3$, an open-sourced \textbf{A}utomatic \textbf{C}apability \textbf{E}valuator for \textbf{M}ultimodal \textbf{M}edical \textbf{M}odels specifically designed to assess the question answering abilities of medical MLLMs. It first utilizes a branch-merge architecture to provide both detailed analysis and a concise final score based on standard medical evaluation criteria. Subsequently, a reward token-based direct preference optimization (RTDPO) strategy is incorporated to save training time without compromising performance of our model. Extensive experiments have demonstrated the effectiveness of our ACE-$M^3$ model\footnote{\url{https://huggingface.co/collections/AIUSRTMP/ace-m3-67593297ff391b93e3e5d068}} in evaluating the capabilities of medical MLLMs.

Machine Unlearning on Pre-trained Models by Residual Feature Alignment Using LoRA

Machine unlearning is new emerged technology that removes a subset of the training data from a trained model without affecting the model performance on the remaining data. This topic is becoming increasingly important in protecting user privacy and eliminating harmful or outdated data. The key challenge lies in effectively and efficiently unlearning specific information without compromising the model's utility on the retained data. For the pre-trained models, fine-tuning is an important way to achieve the unlearning target. Previous work typically fine-tuned the entire model's parameters, which incurs significant computation costs. In addition, the fine-tuning process may cause shifts in the intermediate layer features, affecting the model's overall utility. In this work, we propose a novel and efficient machine unlearning method on pre-trained models. We term the method as Residual Feature Alignment Unlearning. Specifically, we leverage LoRA (Low-Rank Adaptation) to decompose the model's intermediate features into pre-trained features and residual features. By adjusting the residual features, we align the unlearned model with the pre-trained model at the intermediate feature level to achieve both unlearning and remaining targets. The method aims to learn the zero residuals on the retained set and shifted residuals on the unlearning set. Extensive experiments on numerous datasets validate the effectiveness of our approach.

CliMedBench: A Large-Scale Chinese Benchmark for Evaluating Medical Large Language Models in Clinical Scenarios

With the proliferation of Large Language Models (LLMs) in diverse domains, there is a particular need for unified evaluation standards in clinical medical scenarios, where models need to be examined very thoroughly. We present CliMedBench, a comprehensive benchmark with 14 expert-guided core clinical scenarios specifically designed to assess the medical ability of LLMs across 7 pivot dimensions. It comprises 33,735 questions derived from real-world medical reports of top-tier tertiary hospitals and authentic examination exercises. The reliability of this benchmark has been confirmed in several ways. Subsequent experiments with existing LLMs have led to the following findings: (i) Chinese medical LLMs underperform on this benchmark, especially where medical reasoning and factual consistency are vital, underscoring the need for advances in clinical knowledge and diagnostic accuracy. (ii) Several general-domain LLMs demonstrate substantial potential in medical clinics, while the limited input capacity of many medical LLMs hinders their practical use. These findings reveal both the strengths and limitations of LLMs in clinical scenarios and offer critical insights for medical research.

Fine-Grained Scene Graph Generation via Sample-Level Bias Prediction

Scene Graph Generation (SGG) aims to explore the relationships between objects in images and obtain scene summary graphs, thereby better serving downstream tasks. However, the long-tailed problem has adversely affected the scene graph's quality. The predictions are dominated by coarse-grained relationships, lacking more informative fine-grained ones. The union region of one object pair (i.e., one sample) contains rich and dedicated contextual information, enabling the prediction of the sample-specific bias for refining the original relationship prediction. Therefore, we propose a novel Sample-Level Bias Prediction (SBP) method for fine-grained SGG (SBG). Firstly, we train a classic SGG model and construct a correction bias set by calculating the margin between the ground truth label and the predicted label with one classic SGG model. Then, we devise a Bias-Oriented Generative Adversarial Network (BGAN) that learns to predict the constructed correction biases, which can be utilized to correct the original predictions from coarse-grained relationships to fine-grained ones. The extensive experimental results on VG, GQA, and VG-1800 datasets demonstrate that our SBG outperforms the state-of-the-art methods in terms of Average@K across three mainstream SGG models: Motif, VCtree, and Transformer. Compared to dataset-level correction methods on VG, SBG shows a significant average improvement of 5.6%, 3.9%, and 3.2% on Average@K for tasks PredCls, SGCls, and SGDet, respectively. The code will be available at https://github.com/Zhuzi24/SBG.

Linkage on Security, Privacy and Fairness in Federated Learning: New Balances and New Perspectives

Federated learning is fast becoming a popular paradigm for applications involving mobile devices, banking systems, healthcare, and IoT systems. Hence, over the past five years, researchers have undertaken extensive studies on the privacy leaks, security threats, and fairness associated with these emerging models. For the most part, these three critical concepts have been studied in isolation; however, recent research has revealed that there may be an intricate interplay between them. For instance, some researchers have discovered that pursuing fairness may compromise privacy, or that efforts to enhance security can impact fairness. These emerging insights shed light on the fundamental connections between privacy, security, and fairness within federated learning, and, by delving deeper into these interconnections, we may be able to significantly augment research and development across the field. Consequently, the aim of this survey is to offer comprehensive descriptions of the privacy, security, and fairness issues in federated learning. Moreover, we analyze the complex relationships between these three dimensions of cyber safety and pinpoint the fundamental elements that influence each of them. We contend that there exists a trade-off between privacy and fairness and between security and gradient sharing. On this basis, fairness can function as a bridge between privacy and security to build models that are either more secure or more private. Building upon our observations, we identify the trade-offs between privacy and fairness and between security and fairness within the context of federated learning. The survey then concludes with promising directions for future research in this vanguard field.

SkySenseGPT: A Fine-Grained Instruction Tuning Dataset and Model for Remote Sensing Vision-Language Understanding

Remote Sensing Large Multi-Modal Models (RSLMMs) are developing rapidly and showcase significant capabilities in remote sensing imagery (RSI) comprehension. However, due to the limitations of existing datasets, RSLMMs have shortcomings in understanding the rich semantic relations among objects in complex remote sensing scenes. To unlock RSLMMs' complex comprehension ability, we propose a large-scale instruction tuning dataset FIT-RS, containing 1,800,851 instruction samples. FIT-RS covers common interpretation tasks and innovatively introduces several complex comprehension tasks of escalating difficulty, ranging from relation reasoning to image-level scene graph generation. Based on FIT-RS, we build the FIT-RSFG benchmark. Furthermore, we establish a new benchmark to evaluate the fine-grained relation comprehension capabilities of LMMs, named FIT-RSRC. Based on combined instruction data, we propose SkySenseGPT, which achieves outstanding performance on both public datasets and FIT-RSFG, surpassing existing RSLMMs. We hope the FIT-RS dataset can enhance the relation comprehension capability of RSLMMs and provide a large-scale fine-grained data source for the remote sensing community. The dataset will be available at https://github.com/Luo-Z13/SkySenseGPT

Scene Graph Generation in Large-Size VHR Satellite Imagery: A Large-Scale Dataset and A Context-Aware Approach

Scene graph generation (SGG) in satellite imagery (SAI) benefits promoting intelligent understanding of geospatial scenarios from perception to cognition. In SAI, objects exhibit great variations in scales and aspect ratios, and there exist rich relationships between objects (even between spatially disjoint objects), which makes it necessary to holistically conduct SGG in large-size very-high-resolution (VHR) SAI. However, the lack of SGG datasets with large-size VHR SAI has constrained the advancement of SGG in SAI. Due to the complexity of large-size VHR SAI, mining triplets <subject, relationship, object> in large-size VHR SAI heavily relies on long-range contextual reasoning. Consequently, SGG models designed for small-size natural imagery are not directly applicable to large-size VHR SAI. To address the scarcity of datasets, this paper constructs a large-scale dataset for SGG in large-size VHR SAI with image sizes ranging from 512 x 768 to 27,860 x 31,096 pixels, named RSG, encompassing over 210,000 objects and more than 400,000 triplets. To realize SGG in large-size VHR SAI, we propose a context-aware cascade cognition (CAC) framework to understand SAI at three levels: object detection (OBD), pair pruning and relationship prediction. As a fundamental prerequisite for SGG in large-size SAI, a holistic multi-class object detection network (HOD-Net) that can flexibly integrate multi-scale contexts is proposed. With the consideration that there exist a huge amount of object pairs in large-size SAI but only a minority of object pairs contain meaningful relationships, we design a pair proposal generation (PPG) network via adversarial reconstruction to select high-value pairs. Furthermore, a relationship prediction network with context-aware messaging (RPCM) is proposed to predict the relationship types of these pairs.

A safety realignment framework via subspace-oriented model fusion for large language models

The current safeguard mechanisms for large language models (LLMs) are indeed susceptible to jailbreak attacks, making them inherently fragile. Even the process of fine-tuning on apparently benign data for downstream tasks can jeopardize safety. One potential solution is to conduct safety fine-tuning subsequent to downstream fine-tuning. However, there's a risk of catastrophic forgetting during safety fine-tuning, where LLMs may regain safety measures but lose the task-specific knowledge acquired during downstream fine-tuning. In this paper, we introduce a safety realignment framework through subspace-oriented model fusion (SOMF), aiming to combine the safeguard capabilities of initially aligned model and the current fine-tuned model into a realigned model. Our approach begins by disentangling all task vectors from the weights of each fine-tuned model. We then identify safety-related regions within these vectors by subspace masking techniques. Finally, we explore the fusion of the initial safely aligned LLM with all task vectors based on the identified safety subspace. We validate that our safety realignment framework satisfies the safety requirements of a single fine-tuned model as well as multiple models during their fusion. Our findings confirm that SOMF preserves safety without notably compromising performance on downstream tasks, including instruction following in Chinese, English, and Hindi, as well as problem-solving capabilities in Code and Math.