A Survey on Computational Pathology Foundation Models: Datasets, Adaptation Strategies, and Evaluation Tasks

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images. These models, categorized into uni-modal and multi-modal frameworks, have demonstrated promise in automating complex pathology tasks such as segmentation, classification, and biomarker discovery. However, the development of CPathFMs presents significant challenges, such as limited data accessibility, high variability across datasets, the necessity for domain-specific adaptation, and the lack of standardized evaluation benchmarks. This survey provides a comprehensive review of CPathFMs in computational pathology, focusing on datasets, adaptation strategies, and evaluation tasks. We analyze key techniques, such as contrastive learning and multi-modal integration, and highlight existing gaps in current research. Finally, we explore future directions from four perspectives for advancing CPathFMs. This survey serves as a valuable resource for researchers, clinicians, and AI practitioners, guiding the advancement of CPathFMs toward robust and clinically applicable AI-driven pathology solutions.

Power Failure Cascade Prediction using Graph Neural Networks

We consider the problem of predicting power failure cascades due to branch failures. We propose a flow-free model based on graph neural networks that predicts grid states at every generation of a cascade process given an initial contingency and power injection values. We train the proposed model using a cascade sequence data pool generated from simulations. We then evaluate our model at various levels of granularity. We present several error metrics that gauge the model's ability to predict the failure size, the final grid state, and the failure time steps of each branch within the cascade. We benchmark the graph neural network model against influence models. We show that, in addition to being generic over randomly scaled power injection values, the graph neural network model outperforms multiple influence models that are built specifically for their corresponding loading profiles. Finally, we show that the proposed model reduces the computational time by almost two orders of magnitude.

Rapid hyperspectral photothermal mid-infrared spectroscopic imaging from sparse data for gynecologic cancer tissue subtyping

Ovarian cancer detection has traditionally relied on a multi-step process that includes biopsy, tissue staining, and morphological analysis by experienced pathologists. While widely practiced, this conventional approach suffers from several drawbacks: it is qualitative, time-intensive, and heavily dependent on the quality of staining. Mid-infrared (MIR) hyperspectral photothermal imaging is a label-free, biochemically quantitative technology that, when combined with machine learning algorithms, can eliminate the need for staining and provide quantitative results comparable to traditional histology. However, this technology is slow. This work presents a novel approach to MIR photothermal imaging that enhances its speed by an order of magnitude. Our method significantly accelerates data collection by capturing a combination of high-resolution and interleaved, lower-resolution infrared band images and applying computational techniques for data interpolation. We effectively minimize data collection requirements by leveraging sparse data acquisition and employing curvelet-based reconstruction algorithms. This method enables the reconstruction of high-quality, high-resolution images from undersampled datasets and achieving a 10X improvement in data acquisition time. We assessed the performance of our sparse imaging methodology using a variety of quantitative metrics, including mean squared error (MSE), structural similarity index (SSIM), and tissue subtype classification accuracies, employing both random forest and convolutional neural network (CNN) models, accompanied by ROC curves. Our statistically robust analysis, based on data from 100 ovarian cancer patient samples and over 65 million data points, demonstrates the method's capability to produce superior image quality and accurately distinguish between different gynecological tissue types with segmentation accuracy exceeding 95%.

Radarize: Large-Scale Radar SLAM for Indoor Environments

We present Radarize, a self-contained SLAM pipeline for indoor environments that uses only a low-cost commodity single-chip mmWave radar. Our radar-native approach leverages phenomena unique to radio frequencies, such as doppler shift-based odometry, to improve performance. We evaluate our method on a large-scale dataset of 146 trajectories spanning 4 campus buildings, totaling approximately 4680m of travel distance. Our results show that our method outperforms state-of-the-art radar-based approaches by approximately 5x in terms of odometry and 8x in terms of end-to-end SLAM, as measured by absolute trajectory error (ATE), without the need additional sensors such as IMUs or wheel odometry.

Effective Multi-Agent Deep Reinforcement Learning Control with Relative Entropy Regularization

In this paper, a novel Multi-agent Reinforcement Learning (MARL) approach, Multi-Agent Continuous Dynamic Policy Gradient (MACDPP) was proposed to tackle the issues of limited capability and sample efficiency in various scenarios controlled by multiple agents. It alleviates the inconsistency of multiple agents' policy updates by introducing the relative entropy regularization to the Centralized Training with Decentralized Execution (CTDE) framework with the Actor-Critic (AC) structure. Evaluated by multi-agent cooperation and competition tasks and traditional control tasks including OpenAI benchmarks and robot arm manipulation, MACDPP demonstrates significant superiority in learning capability and sample efficiency compared with both related multi-agent and widely implemented signal-agent baselines and therefore expands the potential of MARL in effectively learning challenging control scenarios.

Practical Probabilistic Model-based Deep Reinforcement Learning by Integrating Dropout Uncertainty and Trajectory Sampling

This paper addresses the prediction stability, prediction accuracy and control capability of the current probabilistic model-based reinforcement learning (MBRL) built on neural networks. A novel approach dropout-based probabilistic ensembles with trajectory sampling (DPETS) is proposed where the system uncertainty is stably predicted by combining the Monte-Carlo dropout and trajectory sampling in one framework. Its loss function is designed to correct the fitting error of neural networks for more accurate prediction of probabilistic models. The state propagation in its policy is extended to filter the aleatoric uncertainty for superior control capability. Evaluated by several Mujoco benchmark control tasks under additional disturbances and one practical robot arm manipulation task, DPETS outperforms related MBRL approaches in both average return and convergence velocity while achieving superior performance than well-known model-free baselines with significant sample efficiency. The open source code of DPETS is available at https://github.com/mrjun123/DPETS.

A Self-supervised Contrastive Learning Method for Grasp Outcomes Prediction

In this paper, we investigate the effectiveness of contrastive learning methods for predicting grasp outcomes in an unsupervised manner. By utilizing a publicly available dataset, we demonstrate that contrastive learning methods perform well on the task of grasp outcomes prediction. Specifically, the dynamic-dictionary-based method with the momentum updating technique achieves a satisfactory accuracy of 81.83% using data from one single tactile sensor, outperforming other unsupervised methods. Our results reveal the potential of contrastive learning methods for applications in the field of robot grasping and highlight the importance of accurate grasp prediction for achieving stable grasps.

MergeComp: A Compression Scheduler for Scalable Communication-Efficient Distributed Training

Large-scale distributed training is increasingly becoming communication bound. Many gradient compression algorithms have been proposed to reduce the communication overhead and improve scalability. However, it has been observed that in some cases gradient compression may even harm the performance of distributed training. In this paper, we propose MergeComp, a compression scheduler to optimize the scalability of communication-efficient distributed training. It automatically schedules the compression operations to optimize the performance of compression algorithms without the knowledge of model architectures or system parameters. We have applied MergeComp to nine popular compression algorithms. Our evaluations show that MergeComp can improve the performance of compression algorithms by up to 3.83x without losing accuracy. It can even achieve a scaling factor of distributed training up to 99% over high-speed networks.

Real-time Whole-body Obstacle Avoidance for 7-DOF Redundant Manipulators

Mainly because of the heavy computational costs, the real-time whole-body obstacle avoidance for the redundant manipulators has not been well implemented. This paper presents an approach that can ensure that the whole-body of a redundant manipulator can avoid moving obstacles in real-time during the execution of a task. The manipulator is divided into end-effector and non-end-effector portion. Based on dynamical systems (DS), the real-time end-effector obstacle avoidance is obtained. Besides, the end-effector can reach the given target. By using null-space velocity control, the real-time non-endeffector obstacle avoidance is achieved. Finally, a controller is designed to ensure the whole-body obstacle avoidance. We validate the effectiveness of the method in the simulations and experiments on the 7-DOF arm of the UBTECH humanoid robot.

Dynamical Systems based Obstacle Avoidance with Workspace Constraint for Manipulators

In this paper, based on Dynamical Systems (DS), we present an obstacle avoidance method that take into account workspace constraint for serial manipulators. Two modulation matrices that consider the effect of an obstacle and the workspace of a manipulator are determined when the obstacle does not intersect the workspace boundary and when the obstacle intersects the workspace boundary respectively. Using the modulation matrices, an original DS is deformed. The proposed approach can ensure that the trajectory of the manipulator computed according to the deformed DS neither penetrate the obstacle nor go out of the workspace. We validate the effectiveness of the approach in the simulations and experiments on the left arm of the UBTECH humanoid robot.