Time-Varying Coronary Artery Deformation: A Dynamic Skinning Framework for Surgical Training

Purpose: This study proposes a novel anatomically-driven dynamic modeling framework for coronary arteries using skeletal skinning weights computation, aiming to achieve precise control over vessel deformation while maintaining real-time performance for surgical simulation applications. Methods: We developed a computational framework based on biharmonic energy minimization for skinning weight calculation, incorporating volumetric discretization through tetrahedral mesh generation. The method implements temporal sampling and interpolation for continuous vessel deformation throughout the cardiac cycle, with mechanical constraints and volume conservation enforcement. The framework was validated using clinical datasets from 5 patients, comparing interpolated deformation results against ground truth data obtained from frame-by-frame segmentation across cardiac phases. Results: The proposed framework effectively handled interactive vessel manipulation. Geometric accuracy evaluation showed mean Hausdorff distance of 4.96 +- 1.78 mm and mean surface distance of 1.78 +- 0.75 mm between interpolated meshes and ground truth models. The Branch Completeness Ratio achieved 1.82 +- 0.46, while Branch Continuity Score maintained 0.84 +- 0.06 (scale 0-1) across all datasets. The system demonstrated capability in supporting real-time guidewire-vessel collision detection and contrast medium flow simulation throughout the complete coronary tree structure. Conclusion: Our skinning weight-based methodology enhances model interactivity and applicability while maintaining geometric accuracy. The framework provides a more flexible technical foundation for virtual surgical training systems, demonstrating promising potential for both clinical practice and medical education applications. The code is available at https://github.com/ipoirot/DynamicArtery.

Rethinking Fine-Tuning when Scaling Test-Time Compute: Limiting Confidence Improves Mathematical Reasoning

Recent progress in large language models (LLMs) highlights the power of scaling test-time compute to achieve strong performance on complex tasks, such as mathematical reasoning and code generation. This raises a critical question: how should model training be modified to optimize performance under a subsequent test-time compute strategy and budget? To explore this, we focus on pass@N, a simple test-time strategy that searches for a correct answer in $N$ independent samples. We show, surprisingly, that training with cross-entropy (CE) loss can be ${\it misaligned}$ with pass@N in that pass@N accuracy ${\it decreases}$ with longer training. We explain the origins of this misalignment in terms of model overconfidence induced by CE, and experimentally verify our prediction of overconfidence as an impediment to scaling test-time compute via pass@N. Furthermore we suggest a principled, modified training loss that is better aligned to pass@N by limiting model confidence and rescuing pass@N test performance. Our algorithm demonstrates improved mathematical reasoning on MATH and MiniF2F benchmarks under several scenarios: (1) providing answers to math questions; and (2) proving theorems by searching over proof trees of varying shapes. Overall our work underscores the importance of co-designing two traditionally separate phases of LLM development: training-time protocols and test-time search and reasoning strategies.

Erasing Noise in Signal Detection with Diffusion Model: From Theory to Application

In this paper, a signal detection method based on the denoise diffusion model (DM) is proposed, which outperforms the maximum likelihood (ML) estimation method that has long been regarded as the optimal signal detection technique. Theoretically, a novel mathematical theory for intelligent signal detection based on stochastic differential equations (SDEs) is established in this paper, demonstrating the effectiveness of DM in reducing the additive white Gaussian noise in received signals. Moreover, a mathematical relationship between the signal-to-noise ratio (SNR) and the timestep in DM is established, revealing that for any given SNR, a corresponding optimal timestep can be identified. Furthermore, to address potential issues with out-of-distribution inputs in the DM, we employ a mathematical scaling technique that allows the trained DM to handle signal detection across a wide range of SNRs without any fine-tuning. Building on the above theoretical foundation, we propose a DM-based signal detection method, with the diffusion transformer (DiT) serving as the backbone neural network, whose computational complexity of this method is $\mathcal{O}(n^2)$. Simulation results demonstrate that, for BPSK and QAM modulation schemes, the DM-based method achieves a significantly lower symbol error rate (SER) compared to ML estimation, while maintaining a much lower computational complexity.

QoE-oriented Communication Service Provision for Annotation Rendering in Mobile Augmented Reality

As mobile augmented reality (MAR) continues to evolve, future 6G networks will play a pivotal role in supporting immersive and personalized user experiences. In this paper, we address the communication service provision problem for annotation rendering in edge-assisted MAR, with the objective of optimizing spectrum resource utilization while ensuring the required quality of experience (QoE) for MAR users. To overcome the challenges of user-specific uplink data traffic patterns and the complex operational mechanisms of annotation rendering, we propose a digital twin (DT)-based approach. We first design a DT specifically tailored for MAR applications to learn key annotation rendering mechanisms, enabling the network controller to access MAR application-specific information. Then, we develop a DT based QoE modeling approach to capture the unique relationship between individual user QoE and spectrum resource demands. Finally, we propose a QoE-oriented resource allocation algorithm that decreases resource utilization compared to conventional net work slicing-based approaches. Simulation results demonstrate that our DT-based approach outperforms benchmark approaches in the accuracy and granularity of QoE modeling.

Is AI Robust Enough for Scientific Research?

We uncover a phenomenon largely overlooked by the scientific community utilizing AI: neural networks exhibit high susceptibility to minute perturbations, resulting in significant deviations in their outputs. Through an analysis of five diverse application areas -- weather forecasting, chemical energy and force calculations, fluid dynamics, quantum chromodynamics, and wireless communication -- we demonstrate that this vulnerability is a broad and general characteristic of AI systems. This revelation exposes a hidden risk in relying on neural networks for essential scientific computations, calling further studies on their reliability and security.

DRL-Based Optimization for AoI and Energy Consumption in C-V2X Enabled IoV

To address communication latency issues, the Third Generation Partnership Project (3GPP) has defined Cellular-Vehicle to Everything (C-V2X) technology, which includes Vehicle-to-Vehicle (V2V) communication for direct vehicle-to-vehicle communication. However, this method requires vehicles to autonomously select communication resources based on the Semi-Persistent Scheduling (SPS) protocol, which may lead to collisions due to different vehicles sharing the same communication resources, thereby affecting communication effectiveness. Non-Orthogonal Multiple Access (NOMA) is considered a potential solution for handling large-scale vehicle communication, as it can enhance the Signal-to-Interference-plus-Noise Ratio (SINR) by employing Successive Interference Cancellation (SIC), thereby reducing the negative impact of communication collisions. When evaluating vehicle communication performance, traditional metrics such as reliability and transmission delay present certain contradictions. Introducing the new metric Age of Information (AoI) provides a more comprehensive evaluation of communication system. Additionally, to ensure service quality, user terminals need to possess high computational capabilities, which may lead to increased energy consumption, necessitating a trade-off between communication energy consumption and effectiveness. Given the complexity and dynamics of communication systems, Deep Reinforcement Learning (DRL) serves as an intelligent learning method capable of learning optimal strategies in dynamic environments. Therefore, this paper analyzes the effects of multi-priority queues and NOMA on AoI in the C-V2X vehicular communication system and proposes an energy consumption and AoI optimization method based on DRL. Finally, through comparative simulations with baseline methods, the proposed approach demonstrates its advances in terms of energy consumption and AoI.

V2X-Assisted Distributed Computing and Control Framework for Connected and Automated Vehicles under Ramp Merging Scenario

This paper investigates distributed computing and cooperative control of connected and automated vehicles (CAVs) in ramp merging scenario under transportation cyber-physical system. Firstly, a centralized cooperative trajectory planning problem is formulated subject to the safely constraints and traffic performance in ramp merging scenario, where the trajectories of all vehicles are jointly optimized. To get rid of the reliance on a central controller and reduce computation time, a distributed solution to this problem implemented among CAVs through Vehicles-to-Everything (V2X) communication is proposed. Unlike existing method, our method can distribute the computational task among CAVs and carry out parallel solving through V2X communication. Then, a multi-vehicles model predictive control (MPC) problem aimed at maximizing system stability and minimizing control input is formulated based on the solution of the first problem subject to strict safety constants and input limits. Due to these complex constraints, this problem becomes high-dimensional, centralized, and non-convex. To solve it in a short time, a decomposition and convex reformulation method, namely distributed cooperative iterative model predictive control (DCIMPC), is proposed. This method leverages the communication capability of CAVs to decompose the problem, making full use of the computational resources on vehicles to achieve fast solutions and distributed control. The two above problems with their corresponding solving methods form the systemic framework of the V2X assisted distributed computing and control. Simulations have been conducted to evaluate the framework's convergence, safety, and solving speed. Additionally, extra experiments are conducted to validate the performance of DCIMPC. The results show that our method can greatly improve computation speed without sacrificing system performance.

Overcoming False Illusions in Real-World Face Restoration with Multi-Modal Guided Diffusion Model

We introduce a novel Multi-modal Guided Real-World Face Restoration (MGFR) technique designed to improve the quality of facial image restoration from low-quality inputs. Leveraging a blend of attribute text prompts, high-quality reference images, and identity information, MGFR can mitigate the generation of false facial attributes and identities often associated with generative face restoration methods. By incorporating a dual-control adapter and a two-stage training strategy, our method effectively utilizes multi-modal prior information for targeted restoration tasks. We also present the Reface-HQ dataset, comprising over 23,000 high-resolution facial images across 5,000 identities, to address the need for reference face training images. Our approach achieves superior visual quality in restoring facial details under severe degradation and allows for controlled restoration processes, enhancing the accuracy of identity preservation and attribute correction. Including negative quality samples and attribute prompts in the training further refines the model's ability to generate detailed and perceptually accurate images.

Symmetry Breaking in Neural Network Optimization: Insights from Input Dimension Expansion

Understanding the mechanisms behind neural network optimization is crucial for improving network design and performance. While various optimization techniques have been developed, a comprehensive understanding of the underlying principles that govern these techniques remains elusive. Specifically, the role of symmetry breaking, a fundamental concept in physics, has not been fully explored in neural network optimization. This gap in knowledge limits our ability to design networks that are both efficient and effective. Here, we propose the symmetry breaking hypothesis to elucidate the significance of symmetry breaking in enhancing neural network optimization. We demonstrate that a simple input expansion can significantly improve network performance across various tasks, and we show that this improvement can be attributed to the underlying symmetry breaking mechanism. We further develop a metric to quantify the degree of symmetry breaking in neural networks, providing a practical approach to evaluate and guide network design. Our findings confirm that symmetry breaking is a fundamental principle that underpins various optimization techniques, including dropout, batch normalization, and equivariance. By quantifying the degree of symmetry breaking, our work offers a practical technique for performance enhancement and a metric to guide network design without the need for complete datasets and extensive training processes.

DRL-Based Federated Self-Supervised Learning for Task Offloading and Resource Allocation in ISAC-Enabled Vehicle Edge Computing

Intelligent Transportation Systems (ITS) leverage Integrated Sensing and Communications (ISAC) to enhance data exchange between vehicles and infrastructure in the Internet of Vehicles (IoV). This integration inevitably increases computing demands, risking real-time system stability. Vehicle Edge Computing (VEC) addresses this by offloading tasks to Road Side Unit (RSU), ensuring timely services. Our previous work FLSimCo algorithm, which uses local resources for Federated Self-Supervised Learning (SSL), though vehicles often can't complete all iterations task. Our improved algorithm offloads partial task to RSU and optimizes energy consumption by adjusting transmission power, CPU frequency, and task assignment ratios, balancing local and RSU-based training. Meanwhile, setting an offloading threshold further prevents inefficiencies. Simulation results show that the enhanced algorithm reduces energy consumption, improves offloading efficiency and the accuracy of Federated SSL.