An Iterative LLM Framework for SIBT utilizing RAG-based Adaptive Weight Optimization

Seed implant brachytherapy (SIBT) is an effective cancer treatment modality; however, clinical planning often relies on manual adjustment of objective function weights, leading to inefficiencies and suboptimal results. This study proposes an adaptive weight optimization framework for SIBT planning, driven by large language models (LLMs). A locally deployed DeepSeek-R1 LLM is integrated with an automatic planning algorithm in an iterative loop. Starting with fixed weights, the LLM evaluates plan quality and recommends new weights in the next iteration. This process continues until convergence criteria are met, after which the LLM conducts a comprehensive evaluation to identify the optimal plan. A clinical knowledge base, constructed and queried via retrieval-augmented generation (RAG), enhances the model's domain-specific reasoning. The proposed method was validated on 23 patient cases, showing that the LLM-assisted approach produces plans that are comparable to or exceeding clinically approved and fixed-weight plans, in terms of dose homogeneity for the clinical target volume (CTV) and sparing of organs at risk (OARs). The study demonstrates the potential use of LLMs in SIBT planning automation.

EndoUFM: Utilizing Foundation Models for Monocular depth estimation of endoscopic images

Depth estimation is a foundational component for 3D reconstruction in minimally invasive endoscopic surgeries. However, existing monocular depth estimation techniques often exhibit limited performance to the varying illumination and complex textures of the surgical environment. While powerful visual foundation models offer a promising solution, their training on natural images leads to significant domain adaptability limitations and semantic perception deficiencies when applied to endoscopy. In this study, we introduce EndoUFM, an unsupervised monocular depth estimation framework that innovatively integrating dual foundation models for surgical scenes, which enhance the depth estimation performance by leveraging the powerful pre-learned priors. The framework features a novel adaptive fine-tuning strategy that incorporates Random Vector Low-Rank Adaptation (RVLoRA) to enhance model adaptability, and a Residual block based on Depthwise Separable Convolution (Res-DSC) to improve the capture of fine-grained local features. Furthermore, we design a mask-guided smoothness loss to enforce depth consistency within anatomical tissue structures. Extensive experiments on the SCARED, Hamlyn, SERV-CT, and EndoNeRF datasets confirm that our method achieves state-of-the-art performance while maintaining an efficient model size. This work contributes to augmenting surgeons' spatial perception during minimally invasive procedures, thereby enhancing surgical precision and safety, with crucial implications for augmented reality and navigation systems.

Multi-Class Segmentation of Aortic Branches and Zones in Computed Tomography Angiography: The AortaSeg24 Challenge

Multi-class segmentation of the aorta in computed tomography angiography (CTA) scans is essential for diagnosing and planning complex endovascular treatments for patients with aortic dissections. However, existing methods reduce aortic segmentation to a binary problem, limiting their ability to measure diameters across different branches and zones. Furthermore, no open-source dataset is currently available to support the development of multi-class aortic segmentation methods. To address this gap, we organized the AortaSeg24 MICCAI Challenge, introducing the first dataset of 100 CTA volumes annotated for 23 clinically relevant aortic branches and zones. This dataset was designed to facilitate both model development and validation. The challenge attracted 121 teams worldwide, with participants leveraging state-of-the-art frameworks such as nnU-Net and exploring novel techniques, including cascaded models, data augmentation strategies, and custom loss functions. We evaluated the submitted algorithms using the Dice Similarity Coefficient (DSC) and Normalized Surface Distance (NSD), highlighting the approaches adopted by the top five performing teams. This paper presents the challenge design, dataset details, evaluation metrics, and an in-depth analysis of the top-performing algorithms. The annotated dataset, evaluation code, and implementations of the leading methods are publicly available to support further research. All resources can be accessed at https://aortaseg24.grand-challenge.org.

Semantic-CD: Remote Sensing Image Semantic Change Detection towards Open-vocabulary Setting

Remote sensing image semantic change detection is a method used to analyze remote sensing images, aiming to identify areas of change as well as categorize these changes within images of the same location taken at different times. Traditional change detection methods often face challenges in generalizing across semantic categories in practical scenarios. To address this issue, we introduce a novel approach called Semantic-CD, specifically designed for semantic change detection in remote sensing images. This method incorporates the open vocabulary semantics from the vision-language foundation model, CLIP. By utilizing CLIP's extensive vocabulary knowledge, our model enhances its ability to generalize across categories and improves segmentation through fully decoupled multi-task learning, which includes both binary change detection and semantic change detection tasks. Semantic-CD consists of four main components: a bi-temporal CLIP visual encoder for extracting features from bi-temporal images, an open semantic prompter for creating semantic cost volume maps with open vocabulary, a binary change detection decoder for generating binary change detection masks, and a semantic change detection decoder for producing semantic labels. Experimental results on the SECOND dataset demonstrate that Semantic-CD achieves more accurate masks and reduces semantic classification errors, illustrating its effectiveness in applying semantic priors from vision-language foundation models to SCD tasks.

Empirical curvelet based Fully Convolutional Network for supervised texture image segmentation

In this paper, we propose a new approach to perform supervised texture classification/segmentation. The proposed idea is to feed a Fully Convolutional Network with specific texture descriptors. These texture features are extracted from images by using an empirical curvelet transform. We propose a method to build a unique empirical curvelet filter bank adapted to a given dictionary of textures. We then show that the output of these filters can be used to build efficient texture descriptors utilized to finally feed deep learning networks. Our approach is finally evaluated on several datasets and compare the results to various state-of-the-art algorithms and show that the proposed method dramatically outperform all existing ones.

Review of wavelet-based unsupervised texture segmentation, advantage of adaptive wavelets

Wavelet-based segmentation approaches are widely used for texture segmentation purposes because of their ability to characterize different textures. In this paper, we assess the influence of the chosen wavelet and propose to use the recently introduced empirical wavelets. We show that the adaptability of the empirical wavelet permits to reach better results than classic wavelets. In order to focus only on the textural information, we also propose to perform a cartoon + texture decomposition step before applying the segmentation algorithm. The proposed method is tested on six classic benchmarks, based on several popular texture images.

Advancing Depth Anything Model for Unsupervised Monocular Depth Estimation in Endoscopy

Depth estimation is a cornerstone of 3D reconstruction and plays a vital role in minimally invasive endoscopic surgeries. However, most current depth estimation networks rely on traditional convolutional neural networks, which are limited in their ability to capture global information. Foundation models offer a promising avenue for enhancing depth estimation, but those currently available are primarily trained on natural images, leading to suboptimal performance when applied to endoscopic images. In this work, we introduce a novel fine-tuning strategy for the Depth Anything Model and integrate it with an intrinsic-based unsupervised monocular depth estimation framework. Our approach includes a low-rank adaptation technique based on random vectors, which improves the model's adaptability to different scales. Additionally, we propose a residual block built on depthwise separable convolution to compensate for the transformer's limited ability to capture high-frequency details, such as edges and textures. Our experimental results on the SCARED dataset show that our method achieves state-of-the-art performance while minimizing the number of trainable parameters. Applying this method in minimally invasive endoscopic surgery could significantly enhance both the precision and safety of these procedures.

Semantic-CC: Boosting Remote Sensing Image Change Captioning via Foundational Knowledge and Semantic Guidance

Remote sensing image change captioning (RSICC) aims to articulate the changes in objects of interest within bi-temporal remote sensing images using natural language. Given the limitations of current RSICC methods in expressing general features across multi-temporal and spatial scenarios, and their deficiency in providing granular, robust, and precise change descriptions, we introduce a novel change captioning (CC) method based on the foundational knowledge and semantic guidance, which we term Semantic-CC. Semantic-CC alleviates the dependency of high-generalization algorithms on extensive annotations by harnessing the latent knowledge of foundation models, and it generates more comprehensive and accurate change descriptions guided by pixel-level semantics from change detection (CD). Specifically, we propose a bi-temporal SAM-based encoder for dual-image feature extraction; a multi-task semantic aggregation neck for facilitating information interaction between heterogeneous tasks; a straightforward multi-scale change detection decoder to provide pixel-level semantic guidance; and a change caption decoder based on the large language model (LLM) to generate change description sentences. Moreover, to ensure the stability of the joint training of CD and CC, we propose a three-stage training strategy that supervises different tasks at various stages. We validate the proposed method on the LEVIR-CC and LEVIR-CD datasets. The experimental results corroborate the complementarity of CD and CC, demonstrating that Semantic-CC can generate more accurate change descriptions and achieve optimal performance across both tasks.

RT-SRTS: Angle-Agnostic Real-Time Simultaneous 3D Reconstruction and Tumor Segmentation from Single X-Ray Projection

Radiotherapy is one of the primary treatment methods for tumors, but the organ movement caused by respiratory motion limits its accuracy. Recently, 3D imaging from single X-ray projection receives extensive attentions as a promising way to address this issue. However, current methods can only reconstruct 3D image without direct location of the tumor and are only validated for fixed-angle imaging, which fails to fully meet the requirement of motion control in radiotherapy. In this study, we propose a novel imaging method RT-SRTS which integrates 3D imaging and tumor segmentation into one network based on the multi-task learning (MTL) and achieves real-time simultaneous 3D reconstruction and tumor segmentation from single X-ray projection at any angle. Futhermore, we propose the attention enhanced calibrator (AEC) and uncertain-region elaboration (URE) modules to aid feature extraction and improve segmentation accuracy. We evaluated the proposed method on ten patient cases and compared it with two state-of-the-art methods. Our approach not only delivered superior 3D reconstruction but also demonstrated commendable tumor segmentation results. The simultaneous reconstruction and segmentation could be completed in approximately 70 ms, significantly faster than the required time threshold for real-time tumor tracking. The efficacy of both AEC and URE was also validated through ablation studies.

Spatial Temporal Graph Convolution with Graph Structure Self-learning for Early MCI Detection

Graph neural networks (GNNs) have been successfully applied to early mild cognitive impairment (EMCI) detection, with the usage of elaborately designed features constructed from blood oxygen level-dependent (BOLD) time series. However, few works explored the feasibility of using BOLD signals directly as features. Meanwhile, existing GNN-based methods primarily rely on hand-crafted explicit brain topology as the adjacency matrix, which is not optimal and ignores the implicit topological organization of the brain. In this paper, we propose a spatial temporal graph convolutional network with a novel graph structure self-learning mechanism for EMCI detection. The proposed spatial temporal graph convolution block directly exploits BOLD time series as input features, which provides an interesting view for rsfMRI-based preclinical AD diagnosis. Moreover, our model can adaptively learn the optimal topological structure and refine edge weights with the graph structure self-learning mechanism. Results on the Alzheimer's Disease Neuroimaging Initiative (ADNI) database show that our method outperforms state-of-the-art approaches. Biomarkers consistent with previous studies can be extracted from the model, proving the reliable interpretability of our method.