Extracting and Encoding: Leveraging Large Language Models and Medical Knowledge to Enhance Radiological Text Representation

Advancing representation learning in specialized fields like medicine remains challenging due to the scarcity of expert annotations for text and images. To tackle this issue, we present a novel two-stage framework designed to extract high-quality factual statements from free-text radiology reports in order to improve the representations of text encoders and, consequently, their performance on various downstream tasks. In the first stage, we propose a \textit{Fact Extractor} that leverages large language models (LLMs) to identify factual statements from well-curated domain-specific datasets. In the second stage, we introduce a \textit{Fact Encoder} (CXRFE) based on a BERT model fine-tuned with objective functions designed to improve its representations using the extracted factual data. Our framework also includes a new embedding-based metric (CXRFEScore) for evaluating chest X-ray text generation systems, leveraging both stages of our approach. Extensive evaluations show that our fact extractor and encoder outperform current state-of-the-art methods in tasks such as sentence ranking, natural language inference, and label extraction from radiology reports. Additionally, our metric proves to be more robust and effective than existing metrics commonly used in the radiology report generation literature. The code of this project is available at \url{https://github.com/PabloMessina/CXR-Fact-Encoder}.

Long Tail Image Generation Through Feature Space Augmentation and Iterated Learning

Image and multimodal machine learning tasks are very challenging to solve in the case of poorly distributed data. In particular, data availability and privacy restrictions exacerbate these hurdles in the medical domain. The state of the art in image generation quality is held by Latent Diffusion models, making them prime candidates for tackling this problem. However, a few key issues still need to be solved, such as the difficulty in generating data from under-represented classes and a slow inference process. To mitigate these issues, we propose a new method for image augmentation in long-tailed data based on leveraging the rich latent space of pre-trained Stable Diffusion Models. We create a modified separable latent space to mix head and tail class examples. We build this space via Iterated Learning of underlying sparsified embeddings, which we apply to task-specific saliency maps via a K-NN approach. Code is available at https://github.com/SugarFreeManatee/Feature-Space-Augmentation-and-Iterated-Learning

Towards a Comprehensive Human-Centred Evaluation Framework for Explainable AI

While research on explainable AI (XAI) is booming and explanation techniques have proven promising in many application domains, standardised human-centred evaluation procedures are still missing. In addition, current evaluation procedures do not assess XAI methods holistically in the sense that they do not treat explanations' effects on humans as a complex user experience. To tackle this challenge, we propose to adapt the User-Centric Evaluation Framework used in recommender systems: we integrate explanation aspects, summarise explanation properties, indicate relations between them, and categorise metrics that measure these properties. With this comprehensive evaluation framework, we hope to contribute to the human-centred standardisation of XAI evaluation.

Stress Test Evaluation of Biomedical Word Embeddings

The success of pretrained word embeddings has motivated their use in the biomedical domain, with contextualized embeddings yielding remarkable results in several biomedical NLP tasks. However, there is a lack of research on quantifying their behavior under severe "stress" scenarios. In this work, we systematically evaluate three language models with adversarial examples -- automatically constructed tests that allow us to examine how robust the models are. We propose two types of stress scenarios focused on the biomedical named entity recognition (NER) task, one inspired by spelling errors and another based on the use of synonyms for medical terms. Our experiments with three benchmarks show that the performance of the original models decreases considerably, in addition to revealing their weaknesses and strengths. Finally, we show that adversarial training causes the models to improve their robustness and even to exceed the original performance in some cases.

Graphing else matters: exploiting aspect opinions and ratings in explainable graph-based recommendations

The success of neural network embeddings has entailed a renewed interest in using knowledge graphs for a wide variety of machine learning and information retrieval tasks. In particular, current recommendation methods based on graph embeddings have shown state-of-the-art performance. These methods commonly encode latent rating patterns and content features. Different from previous work, in this paper, we propose to exploit embeddings extracted from graphs that combine information from ratings and aspect-based opinions expressed in textual reviews. We then adapt and evaluate state-of-the-art graph embedding techniques over graphs generated from Amazon and Yelp reviews on six domains, outperforming baseline recommenders. Our approach has the advantage of providing explanations which leverage aspect-based opinions given by users about recommended items. Furthermore, we also provide examples of the applicability of recommendations utilizing aspect opinions as explanations in a visualization dashboard, which allows obtaining information about the most and least liked aspects of similar users obtained from the embeddings of an input graph.

AHMoSe: A Knowledge-Based Visual Support System for Selecting Regression Machine Learning Models

Decision support systems have become increasingly popular in the domain of agriculture. With the development of Automated Machine Learning, agricultural experts are now able to train, evaluate and make predictions using cutting edge machine learning (ML) models without the need for much ML knowledge. Although this automated approach has led to successful results in many scenarios, in certain cases (e.g., when few labeled datasets are available) choosing among different models with similar performance metrics is a difficult task. Furthermore, these systems do not commonly allow users to incorporate their domain knowledge that could facilitate the task of model selection, and to gain insight into the prediction system for eventual decision making. To address these issues, in this paper we present AHMoSe, a visual support system that allows domain experts to better understand, diagnose and compare different regression models, primarily by enriching model-agnostic explanations with domain knowledge. To validate AHMoSE, we describe a use case scenario in the viticulture domain, grape quality prediction, where the system enables users to diagnose and select prediction models that perform better. We also discuss feedback concerning the design of the tool from both ML and viticulture experts.

Neural language models for text classification in evidence-based medicine

The COVID-19 has brought about a significant challenge to the whole of humanity, but with a special burden upon the medical community. Clinicians must keep updated continuously about symptoms, diagnoses, and effectiveness of emergent treatments under a never-ending flood of scientific literature. In this context, the role of evidence-based medicine (EBM) for curating the most substantial evidence to support public health and clinical practice turns essential but is being challenged as never before due to the high volume of research articles published and pre-prints posted daily. Artificial Intelligence can have a crucial role in this situation. In this article, we report the results of an applied research project to classify scientific articles to support Epistemonikos, one of the most active foundations worldwide conducting EBM. We test several methods, and the best one, based on the XLNet neural language model, improves the current approach by 93\% on average F1-score, saving valuable time from physicians who volunteer to curate COVID-19 research articles manually.

Inspecting state of the art performance and NLP metrics in image-based medical report generation

Several deep learning architectures have been proposed over the last years to deal with the problem of generating a written report given an imaging exam as input. Most works evaluate the generated reports using standard Natural Language Processing (NLP) metrics (e.g. BLEU, ROUGE), reporting significant progress. In this article, we contrast this progress by comparing state of the art (SOTA) models against weak baselines. We show that simple and even naive approaches yield near SOTA performance on most traditional NLP metrics. We conclude that evaluation methods in this task should be further studied towards correctly measuring clinical accuracy, ideally involving physicians to contribute to this end.

A Survey on Deep Learning and Explainability for Automatic Image-based Medical Report Generation

Every year physicians face an increasing demand of image-based diagnosis from patients, a problem that can be addressed with recent artificial intelligence methods. In this context, we survey works in the area of automatic report generation from medical images, with emphasis on methods using deep neural networks, with respect to: (1) Datasets, (2) Architecture Design, (3) Explainability and (4) Evaluation Metrics. Our survey identifies interesting developments, but also remaining challenges. Among them, the current evaluation of generated reports is especially weak, since it mostly relies on traditional Natural Language Processing (NLP) metrics, which do not accurately capture medical correctness.

CuratorNet: Visually-aware Recommendation of Art Images

Although there are several visually-aware recommendation models in domains like fashion or even movies, the art domain lacks thesame level of research attention, despite the recent growth of the online artwork market. To reduce this gap, in this article we introduceCuratorNet, a neural network architecture for visually-aware recommendation of art images. CuratorNet is designed at the core withthe goal of maximizing generalization: the network has a fixed set of parameters that only need to be trained once, and thereafter themodel is able to generalize to new users or items never seen before, without further training. This is achieved by leveraging visualcontent: items are mapped to item vectors through visual embeddings, and users are mapped to user vectors by aggregating the visualcontent of items they have consumed. Besides the model architecture, we also introduce novel triplet sampling strategies to build atraining set for rank learning in the art domain, resulting in more effective learning than naive random sampling. With an evaluationover a real-world dataset of physical paintings, we show that CuratorNet achieves the best performance among several baselines,including the state-of-the-art model VBPR. CuratorNet is motivated and evaluated in the art domain, but its architecture and trainingscheme could be adapted to recommend images in other areas