ERANet: Edge Replacement Augmentation for Semi-Supervised Meniscus Segmentation with Prototype Consistency Alignment and Conditional Self-Training

Manual segmentation is labor-intensive, and automatic segmentation remains challenging due to the inherent variability in meniscal morphology, partial volume effects, and low contrast between the meniscus and surrounding tissues. To address these challenges, we propose ERANet, an innovative semi-supervised framework for meniscus segmentation that effectively leverages both labeled and unlabeled images through advanced augmentation and learning strategies. ERANet integrates three key components: edge replacement augmentation (ERA), prototype consistency alignment (PCA), and a conditional self-training (CST) strategy within a mean teacher architecture. ERA introduces anatomically relevant perturbations by simulating meniscal variations, ensuring that augmentations align with the structural context. PCA enhances segmentation performance by aligning intra-class features and promoting compact, discriminative feature representations, particularly in scenarios with limited labeled data. CST improves segmentation robustness by iteratively refining pseudo-labels and mitigating the impact of label noise during training. Together, these innovations establish ERANet as a robust and scalable solution for meniscus segmentation, effectively addressing key barriers to practical implementation. We validated ERANet comprehensively on 3D Double Echo Steady State (DESS) and 3D Fast/Turbo Spin Echo (FSE/TSE) MRI sequences. The results demonstrate the superior performance of ERANet compared to state-of-the-art methods. The proposed framework achieves reliable and accurate segmentation of meniscus structures, even when trained on minimal labeled data. Extensive ablation studies further highlight the synergistic contributions of ERA, PCA, and CST, solidifying ERANet as a transformative solution for semi-supervised meniscus segmentation in medical imaging.

WaveNet-SF: A Hybrid Network for Retinal Disease Detection Based on Wavelet Transform in the Spatial-Frequency Domain

Retinal diseases are a leading cause of vision impairment and blindness, with timely diagnosis being critical for effective treatment. Optical Coherence Tomography (OCT) has become a standard imaging modality for retinal disease diagnosis, but OCT images often suffer from issues such as speckle noise, complex lesion shapes, and varying lesion sizes, making interpretation challenging. In this paper, we propose a novel framework, WaveNet-SF, to enhance retinal disease detection by integrating spatial-domain and frequency-domain learning. The framework utilizes wavelet transforms to decompose OCT images into low- and high-frequency components, enabling the model to extract both global structural features and fine-grained details. To improve lesion detection, we introduce a multi-scale wavelet spatial attention (MSW-SA) module, which enhances the model's focus on regions of interest at multiple scales. Additionally, a high-frequency feature compensation block (HFFC) is incorporated to recover edge information lost during wavelet decomposition, suppress noise, and preserve fine details crucial for lesion detection. Our approach achieves state-of-the-art (SOTA) classification accuracies of 97.82% and 99. 58% on the OCT-C8 and OCT2017 datasets, respectively, surpassing existing methods. These results demonstrate the efficacy of WaveNet-SF in addressing the challenges of OCT image analysis and its potential as a powerful tool for retinal disease diagnosis.

DGSSA: Domain generalization with structural and stylistic augmentation for retinal vessel segmentation

Retinal vascular morphology is crucial for diagnosing diseases such as diabetes, glaucoma, and hypertension, making accurate segmentation of retinal vessels essential for early intervention. Traditional segmentation methods assume that training and testing data share similar distributions, which can lead to poor performance on unseen domains due to domain shifts caused by variations in imaging devices and patient demographics. This paper presents a novel approach, DGSSA, for retinal vessel image segmentation that enhances model generalization by combining structural and style augmentation strategies. We utilize a space colonization algorithm to generate diverse vascular-like structures that closely mimic actual retinal vessels, which are then used to generate pseudo-retinal images with an improved Pix2Pix model, allowing the segmentation model to learn a broader range of structure distributions. Additionally, we utilize PixMix to implement random photometric augmentations and introduce uncertainty perturbations, thereby enriching stylistic diversity and significantly enhancing the model's adaptability to varying imaging conditions. Our framework has been rigorously evaluated on four challenging datasets-DRIVE, CHASEDB, HRF, and STARE-demonstrating state-of-the-art performance that surpasses existing methods. This validates the effectiveness of our proposed approach, highlighting its potential for clinical application in automated retinal vessel analysis.

Enhancing Contrastive Learning Inspired by the Philosophy of "The Blind Men and the Elephant"

Contrastive learning is a prevalent technique in self-supervised vision representation learning, typically generating positive pairs by applying two data augmentations to the same image. Designing effective data augmentation strategies is crucial for the success of contrastive learning. Inspired by the story of the blind men and the elephant, we introduce JointCrop and JointBlur. These methods generate more challenging positive pairs by leveraging the joint distribution of the two augmentation parameters, thereby enabling contrastive learning to acquire more effective feature representations. To the best of our knowledge, this is the first effort to explicitly incorporate the joint distribution of two data augmentation parameters into contrastive learning. As a plug-and-play framework without additional computational overhead, JointCrop and JointBlur enhance the performance of SimCLR, BYOL, MoCo v1, MoCo v2, MoCo v3, SimSiam, and Dino baselines with notable improvements.

DHCP: Detecting Hallucinations by Cross-modal Attention Pattern in Large Vision-Language Models

Large vision-language models (LVLMs) have demonstrated exceptional performance on complex multimodal tasks. However, they continue to suffer from significant hallucination issues, including object, attribute, and relational hallucinations. To accurately detect these hallucinations, we investigated the variations in cross-modal attention patterns between hallucination and non-hallucination states. Leveraging these distinctions, we developed a lightweight detector capable of identifying hallucinations. Our proposed method, Detecting Hallucinations by Cross-modal Attention Patterns (DHCP), is straightforward and does not require additional LVLM training or extra LVLM inference steps. Experimental results show that DHCP achieves remarkable performance in hallucination detection. By offering novel insights into the identification and analysis of hallucinations in LVLMs, DHCP contributes to advancing the reliability and trustworthiness of these models.

PIP: Detecting Adversarial Examples in Large Vision-Language Models via Attention Patterns of Irrelevant Probe Questions

Large Vision-Language Models (LVLMs) have demonstrated their powerful multimodal capabilities. However, they also face serious safety problems, as adversaries can induce robustness issues in LVLMs through the use of well-designed adversarial examples. Therefore, LVLMs are in urgent need of detection tools for adversarial examples to prevent incorrect responses. In this work, we first discover that LVLMs exhibit regular attention patterns for clean images when presented with probe questions. We propose an unconventional method named PIP, which utilizes the attention patterns of one randomly selected irrelevant probe question (e.g., "Is there a clock?") to distinguish adversarial examples from clean examples. Regardless of the image to be tested and its corresponding question, PIP only needs to perform one additional inference of the image to be tested and the probe question, and then achieves successful detection of adversarial examples. Even under black-box attacks and open dataset scenarios, our PIP, coupled with a simple SVM, still achieves more than 98% recall and a precision of over 90%. Our PIP is the first attempt to detect adversarial attacks on LVLMs via simple irrelevant probe questions, shedding light on deeper understanding and introspection within LVLMs. The code is available at https://github.com/btzyd/pip.

BRAU-Net++: U-Shaped Hybrid CNN-Transformer Network for Medical Image Segmentation

Accurate medical image segmentation is essential for clinical quantification, disease diagnosis, treatment planning and many other applications. Both convolution-based and transformer-based u-shaped architectures have made significant success in various medical image segmentation tasks. The former can efficiently learn local information of images while requiring much more image-specific inductive biases inherent to convolution operation. The latter can effectively capture long-range dependency at different feature scales using self-attention, whereas it typically encounters the challenges of quadratic compute and memory requirements with sequence length increasing. To address this problem, through integrating the merits of these two paradigms in a well-designed u-shaped architecture, we propose a hybrid yet effective CNN-Transformer network, named BRAU-Net++, for an accurate medical image segmentation task. Specifically, BRAU-Net++ uses bi-level routing attention as the core building block to design our u-shaped encoder-decoder structure, in which both encoder and decoder are hierarchically constructed, so as to learn global semantic information while reducing computational complexity. Furthermore, this network restructures skip connection by incorporating channel-spatial attention which adopts convolution operations, aiming to minimize local spatial information loss and amplify global dimension-interaction of multi-scale features. Extensive experiments on three public benchmark datasets demonstrate that our proposed approach surpasses other state-of-the-art methods including its baseline: BRAU-Net under almost all evaluation metrics. We achieve the average Dice-Similarity Coefficient (DSC) of 82.47, 90.10, and 92.94 on Synapse multi-organ segmentation, ISIC-2018 Challenge, and CVC-ClinicDB, as well as the mIoU of 84.01 and 88.17 on ISIC-2018 Challenge and CVC-ClinicDB, respectively.

EAFP-Med: An Efficient Adaptive Feature Processing Module Based on Prompts for Medical Image Detection

In the face of rapid advances in medical imaging, cross-domain adaptive medical image detection is challenging due to the differences in lesion representations across various medical imaging technologies. To address this issue, we draw inspiration from large language models to propose EAFP-Med, an efficient adaptive feature processing module based on prompts for medical image detection. EAFP-Med can efficiently extract lesion features of different scales from a diverse range of medical images based on prompts while being flexible and not limited by specific imaging techniques. Furthermore, it serves as a feature preprocessing module that can be connected to any model front-end to enhance the lesion features in input images. Moreover, we propose a novel adaptive disease detection model named EAFP-Med ST, which utilizes the Swin Transformer V2 - Tiny (SwinV2-T) as its backbone and connects it to EAFP-Med. We have compared our method to nine state-of-the-art methods. Experimental results demonstrate that EAFP-Med ST achieves the best performance on all three datasets (chest X-ray images, cranial magnetic resonance imaging images, and skin images). EAFP-Med can efficiently extract lesion features from various medical images based on prompts, enhancing the model's performance. This holds significant potential for improving medical image analysis and diagnosis.

Review of AlexNet for Medical Image Classification

In recent years, the rapid development of deep learning has led to a wide range of applications in the field of medical image classification. The variants of neural network models with ever-increasing performance share some commonalities: to try to mitigate overfitting, improve generalization, avoid gradient vanishing and exploding, etc. AlexNet first utilizes the dropout technique to mitigate overfitting and the ReLU activation function to avoid gradient vanishing. Therefore, we focus our discussion on AlexNet, which has contributed greatly to the development of CNNs in 2012. After reviewing over 40 papers, including journal papers and conference papers, we give a narrative on the technical details, advantages, and application areas of AlexNet.

EEG-DG: A Multi-Source Domain Generalization Framework for Motor Imagery EEG Classification

Motor imagery EEG classification plays a crucial role in non-invasive Brain-Computer Interface (BCI) research. However, the classification is affected by the non-stationarity and individual variations of EEG signals. Simply pooling EEG data with different statistical distributions to train a classification model can severely degrade the generalization performance. To address this issue, the existing methods primarily focus on domain adaptation, which requires access to the target data during training. This is unrealistic in many EEG application scenarios. In this paper, we propose a novel multi-source domain generalization framework called EEG-DG, which leverages multiple source domains with different statistical distributions to build generalizable models on unseen target EEG data. We optimize both the marginal and conditional distributions to ensure the stability of the joint distribution across source domains and extend it to a multi-source domain generalization framework to achieve domain-invariant feature representation, thereby alleviating calibration efforts. Systematic experiments on a simulative dataset and BCI competition datasets IV-2a and IV-2b demonstrate the superiority of our proposed EEG-DG over state-of-the-art methods. Specifically, EEG-DG achieves an average classification accuracy/kappa value of 81.79%/0.7572 and 87.12%/0.7424 on datasets IV-2a and IV-2b, respectively, which even outperforms some domain adaptation methods. Our code is available at https://github.com/XC-ZhongHIT/EEG-DG for free download and evaluation.