Ranking and Combining Latent Structured Predictive Scores without Labeled Data

Combining multiple predictors obtained from distributed data sources to an accurate meta-learner is promising to achieve enhanced performance in lots of prediction problems. As the accuracy of each predictor is usually unknown, integrating the predictors to achieve better performance is challenging. Conventional ensemble learning methods assess the accuracy of predictors based on extensive labeled data. In practical applications, however, the acquisition of such labeled data can prove to be an arduous task. Furthermore, the predictors under consideration may exhibit high degrees of correlation, particularly when similar data sources or machine learning algorithms were employed during their model training. In response to these challenges, this paper introduces a novel structured unsupervised ensemble learning model (SUEL) to exploit the dependency between a set of predictors with continuous predictive scores, rank the predictors without labeled data and combine them to an ensembled score with weights. Two novel correlation-based decomposition algorithms are further proposed to estimate the SUEL model, constrained quadratic optimization (SUEL.CQO) and matrix-factorization-based (SUEL.MF) approaches. The efficacy of the proposed methods is rigorously assessed through both simulation studies and real-world application of risk genes discovery. The results compellingly demonstrate that the proposed methods can efficiently integrate the dependent predictors to an ensemble model without the need of ground truth data.

PADRe: A Unifying Polynomial Attention Drop-in Replacement for Efficient Vision Transformer

We present Polynomial Attention Drop-in Replacement (PADRe), a novel and unifying framework designed to replace the conventional self-attention mechanism in transformer models. Notably, several recent alternative attention mechanisms, including Hyena, Mamba, SimA, Conv2Former, and Castling-ViT, can be viewed as specific instances of our PADRe framework. PADRe leverages polynomial functions and draws upon established results from approximation theory, enhancing computational efficiency without compromising accuracy. PADRe's key components include multiplicative nonlinearities, which we implement using straightforward, hardware-friendly operations such as Hadamard products, incurring only linear computational and memory costs. PADRe further avoids the need for using complex functions such as Softmax, yet it maintains comparable or superior accuracy compared to traditional self-attention. We assess the effectiveness of PADRe as a drop-in replacement for self-attention across diverse computer vision tasks. These tasks include image classification, image-based 2D object detection, and 3D point cloud object detection. Empirical results demonstrate that PADRe runs significantly faster than the conventional self-attention (11x ~ 43x faster on server GPU and mobile NPU) while maintaining similar accuracy when substituting self-attention in the transformer models.

FutureDepth: Learning to Predict the Future Improves Video Depth Estimation

In this paper, we propose a novel video depth estimation approach, FutureDepth, which enables the model to implicitly leverage multi-frame and motion cues to improve depth estimation by making it learn to predict the future at training. More specifically, we propose a future prediction network, F-Net, which takes the features of multiple consecutive frames and is trained to predict multi-frame features one time step ahead iteratively. In this way, F-Net learns the underlying motion and correspondence information, and we incorporate its features into the depth decoding process. Additionally, to enrich the learning of multiframe correspondence cues, we further leverage a reconstruction network, R-Net, which is trained via adaptively masked auto-encoding of multiframe feature volumes. At inference time, both F-Net and R-Net are used to produce queries to work with the depth decoder, as well as a final refinement network. Through extensive experiments on several benchmarks, i.e., NYUDv2, KITTI, DDAD, and Sintel, which cover indoor, driving, and open-domain scenarios, we show that FutureDepth significantly improves upon baseline models, outperforms existing video depth estimation methods, and sets new state-of-the-art (SOTA) accuracy. Furthermore, FutureDepth is more efficient than existing SOTA video depth estimation models and has similar latencies when comparing to monocular models

OpenShape: Scaling Up 3D Shape Representation Towards Open-World Understanding

We introduce OpenShape, a method for learning multi-modal joint representations of text, image, and point clouds. We adopt the commonly used multi-modal contrastive learning framework for representation alignment, but with a specific focus on scaling up 3D representations to enable open-world 3D shape understanding. To achieve this, we scale up training data by ensembling multiple 3D datasets and propose several strategies to automatically filter and enrich noisy text descriptions. We also explore and compare strategies for scaling 3D backbone networks and introduce a novel hard negative mining module for more efficient training. We evaluate OpenShape on zero-shot 3D classification benchmarks and demonstrate its superior capabilities for open-world recognition. Specifically, OpenShape achieves a zero-shot accuracy of 46.8% on the 1,156-category Objaverse-LVIS benchmark, compared to less than 10% for existing methods. OpenShape also achieves an accuracy of 85.3% on ModelNet40, outperforming previous zero-shot baseline methods by 20% and performing on par with some fully-supervised methods. Furthermore, we show that our learned embeddings encode a wide range of visual and semantic concepts (e.g., subcategories, color, shape, style) and facilitate fine-grained text-3D and image-3D interactions. Due to their alignment with CLIP embeddings, our learned shape representations can also be integrated with off-the-shelf CLIP-based models for various applications, such as point cloud captioning and point cloud-conditioned image generation.

PartSLIP: Low-Shot Part Segmentation for 3D Point Clouds via Pretrained Image-Language Models

Generalizable 3D part segmentation is important but challenging in vision and robotics. Training deep models via conventional supervised methods requires large-scale 3D datasets with fine-grained part annotations, which are costly to collect. This paper explores an alternative way for low-shot part segmentation of 3D point clouds by leveraging a pretrained image-language model, GLIP, which achieves superior performance on open-vocabulary 2D detection. We transfer the rich knowledge from 2D to 3D through GLIP-based part detection on point cloud rendering and a novel 2D-to-3D label lifting algorithm. We also utilize multi-view 3D priors and few-shot prompt tuning to boost performance significantly. Extensive evaluation on PartNet and PartNet-Mobility datasets shows that our method enables excellent zero-shot 3D part segmentation. Our few-shot version not only outperforms existing few-shot approaches by a large margin but also achieves highly competitive results compared to the fully supervised counterpart. Furthermore, we demonstrate that our method can be directly applied to iPhone-scanned point clouds without significant domain gaps.

Volumetric Attention for 3D Medical Image Segmentation and Detection

A volumetric attention(VA) module for 3D medical image segmentation and detection is proposed. VA attention is inspired by recent advances in video processing, enables 2.5D networks to leverage context information along the z direction, and allows the use of pretrained 2D detection models when training data is limited, as is often the case for medical applications. Its integration in the Mask R-CNN is shown to enable state-of-the-art performance on the Liver Tumor Segmentation (LiTS) Challenge, outperforming the previous challenge winner by 3.9 points and achieving top performance on the LiTS leader board at the time of paper submission. Detection experiments on the DeepLesion dataset also show that the addition of VA to existing object detectors enables a 69.1 sensitivity at 0.5 false positive per image, outperforming the best published results by 6.6 points.

Validating uncertainty in medical image translation

Medical images are increasingly used as input to deep neural networks to produce quantitative values that aid researchers and clinicians. However, standard deep neural networks do not provide a reliable measure of uncertainty in those quantitative values. Recent work has shown that using dropout during training and testing can provide estimates of uncertainty. In this work, we investigate using dropout to estimate epistemic and aleatoric uncertainty in a CT-to-MR image translation task. We show that both types of uncertainty are captured, as defined, providing confidence in the output uncertainty estimates.

Finding novelty with uncertainty

Medical images are often used to detect and characterize pathology and disease; however, automatically identifying and segmenting pathology in medical images is challenging because the appearance of pathology across diseases varies widely. To address this challenge, we propose a Bayesian deep learning method that learns to translate healthy computed tomography images to magnetic resonance images and simultaneously calculates voxel-wise uncertainty. Since high uncertainty occurs in pathological regions of the image, this uncertainty can be used for unsupervised anomaly segmentation. We show encouraging experimental results on an unsupervised anomaly segmentation task by combining two types of uncertainty into a novel quantity we call scibilic uncertainty.

Validation and Optimization of Multi-Organ Segmentation on Clinical Imaging Archives

Segmentation of abdominal computed tomography(CT) provides spatial context, morphological properties, and a framework for tissue-specific radiomics to guide quantitative Radiological assessment. A 2015 MICCAI challenge spurred substantial innovation in multi-organ abdominal CT segmentation with both traditional and deep learning methods. Recent innovations in deep methods have driven performance toward levels for which clinical translation is appealing. However, continued cross-validation on open datasets presents the risk of indirect knowledge contamination and could result in circular reasoning. Moreover, 'real world' segmentations can be challenging due to the wide variability of abdomen physiology within patients. Herein, we perform two data retrievals to capture clinically acquired deidentified abdominal CT cohorts with respect to a recently published variation on 3D U-Net (baseline algorithm). First, we retrieved 2004 deidentified studies on 476 patients with diagnosis codes involving spleen abnormalities (cohort A). Second, we retrieved 4313 deidentified studies on 1754 patients without diagnosis codes involving spleen abnormalities (cohort B). We perform prospective evaluation of the existing algorithm on both cohorts, yielding 13% and 8% failure rate, respectively. Then, we identified 51 subjects in cohort A with segmentation failures and manually corrected the liver and gallbladder labels. We re-trained the model adding the manual labels, resulting in performance improvement of 9% and 6% failure rate for the A and B cohorts, respectively. In summary, the performance of the baseline on the prospective cohorts was similar to that on previously published datasets. Moreover, adding data from the first cohort substantively improved performance when evaluated on the second withheld validation cohort.

Outlier Guided Optimization of Abdominal Segmentation

Abdominal multi-organ segmentation of computed tomography (CT) images has been the subject of extensive research interest. It presents a substantial challenge in medical image processing, as the shape and distribution of abdominal organs can vary greatly among the population and within an individual over time. While continuous integration of novel datasets into the training set provides potential for better segmentation performance, collection of data at scale is not only costly, but also impractical in some contexts. Moreover, it remains unclear what marginal value additional data have to offer. Herein, we propose a single-pass active learning method through human quality assurance (QA). We built on a pre-trained 3D U-Net model for abdominal multi-organ segmentation and augmented the dataset either with outlier data (e.g., exemplars for which the baseline algorithm failed) or inliers (e.g., exemplars for which the baseline algorithm worked). The new models were trained using the augmented datasets with 5-fold cross-validation (for outlier data) and withheld outlier samples (for inlier data). Manual labeling of outliers increased Dice scores with outliers by 0.130, compared to an increase of 0.067 with inliers (p<0.001, two-tailed paired t-test). By adding 5 to 37 inliers or outliers to training, we find that the marginal value of adding outliers is higher than that of adding inliers. In summary, improvement on single-organ performance was obtained without diminishing multi-organ performance or significantly increasing training time. Hence, identification and correction of baseline failure cases present an effective and efficient method of selecting training data to improve algorithm performance.