Zero-shot Action Localization via the Confidence of Large Vision-Language Models

Precise action localization in untrimmed video is vital for fields such as professional sports and minimally invasive surgery, where the delineation of particular motions in recordings can dramatically enhance analysis. But in many cases, large scale datasets with video-label pairs for localization are unavailable, limiting the opportunity to fine-tune video-understanding models. Recent developments in large vision-language models (LVLM) address this need with impressive zero-shot capabilities in a variety of video understanding tasks. However, the adaptation of image-based LVLMs, with their powerful visual question answering capabilities, to action localization in long-form video is still relatively unexplored. To this end, we introduce a true ZEro-shot Action Localization method (ZEAL). Specifically, we leverage the built-in action knowledge of a large language model (LLM) to inflate actions into highly-detailed descriptions of the archetypal start and end of the action. These descriptions serve as queries to LVLM for generating frame-level confidence scores which can be aggregated to produce localization outputs. The simplicity and flexibility of our method lends it amenable to more capable LVLMs as they are developed, and we demonstrate remarkable results in zero-shot action localization on a challenging benchmark, without any training.

How to Build the Virtual Cell with Artificial Intelligence: Priorities and Opportunities

The cell is arguably the smallest unit of life and is central to understanding biology. Accurate modeling of cells is important for this understanding as well as for determining the root causes of disease. Recent advances in artificial intelligence (AI), combined with the ability to generate large-scale experimental data, present novel opportunities to model cells. Here we propose a vision of AI-powered Virtual Cells, where robust representations of cells and cellular systems under different conditions are directly learned from growing biological data across measurements and scales. We discuss desired capabilities of AI Virtual Cells, including generating universal representations of biological entities across scales, and facilitating interpretable in silico experiments to predict and understand their behavior using Virtual Instruments. We further address the challenges, opportunities and requirements to realize this vision including data needs, evaluation strategies, and community standards and engagement to ensure biological accuracy and broad utility. We envision a future where AI Virtual Cells help identify new drug targets, predict cellular responses to perturbations, as well as scale hypothesis exploration. With open science collaborations across the biomedical ecosystem that includes academia, philanthropy, and the biopharma and AI industries, a comprehensive predictive understanding of cell mechanisms and interactions is within reach.

Continuous Perception Benchmark

Humans continuously perceive and process visual signals. However, current video models typically either sample key frames sparsely or divide videos into chunks and densely sample within each chunk. This approach stems from the fact that most existing video benchmarks can be addressed by analyzing key frames or aggregating information from separate chunks. We anticipate that the next generation of vision models will emulate human perception by processing visual input continuously and holistically. To facilitate the development of such models, we propose the Continuous Perception Benchmark, a video question answering task that cannot be solved by focusing solely on a few frames or by captioning small chunks and then summarizing using language models. Extensive experiments demonstrate that existing models, whether commercial or open-source, struggle with these tasks, indicating the need for new technical advancements in this direction.

Video-STaR: Self-Training Enables Video Instruction Tuning with Any Supervision

The performance of Large Vision Language Models (LVLMs) is dependent on the size and quality of their training datasets. Existing video instruction tuning datasets lack diversity as they are derived by prompting large language models with video captions to generate question-answer pairs, and are therefore mostly descriptive. Meanwhile, many labeled video datasets with diverse labels and supervision exist - however, we find that their integration into LVLMs is non-trivial. Herein, we present Video Self-Training with augmented Reasoning (Video-STaR), the first video self-training approach. Video-STaR allows the utilization of any labeled video dataset for video instruction tuning. In Video-STaR, an LVLM cycles between instruction generation and finetuning, which we show (I) improves general video understanding and (II) adapts LVLMs to novel downstream tasks with existing supervision. During generation, an LVLM is prompted to propose an answer. The answers are then filtered only to those that contain the original video labels, and the LVLM is then re-trained on the generated dataset. By only training on generated answers that contain the correct video labels, Video-STaR utilizes these existing video labels as weak supervision for video instruction tuning. Our results demonstrate that Video-STaR-enhanced LVLMs exhibit improved performance in (I) general video QA, where TempCompass performance improved by 10%, and (II) on downstream tasks, where Video-STaR improved Kinetics700-QA accuracy by 20% and action quality assessment on FineDiving by 15%.

μ-Bench: A Vision-Language Benchmark for Microscopy Understanding

Recent advances in microscopy have enabled the rapid generation of terabytes of image data in cell biology and biomedical research. Vision-language models (VLMs) offer a promising solution for large-scale biological image analysis, enhancing researchers' efficiency, identifying new image biomarkers, and accelerating hypothesis generation and scientific discovery. However, there is a lack of standardized, diverse, and large-scale vision-language benchmarks to evaluate VLMs' perception and cognition capabilities in biological image understanding. To address this gap, we introduce {\mu}-Bench, an expert-curated benchmark encompassing 22 biomedical tasks across various scientific disciplines (biology, pathology), microscopy modalities (electron, fluorescence, light), scales (subcellular, cellular, tissue), and organisms in both normal and abnormal states. We evaluate state-of-the-art biomedical, pathology, and general VLMs on {\mu}-Bench and find that: i) current models struggle on all categories, even for basic tasks such as distinguishing microscopy modalities; ii) current specialist models fine-tuned on biomedical data often perform worse than generalist models; iii) fine-tuning in specific microscopy domains can cause catastrophic forgetting, eroding prior biomedical knowledge encoded in their base model. iv) weight interpolation between fine-tuned and pre-trained models offers one solution to forgetting and improves general performance across biomedical tasks. We release {\mu}-Bench under a permissive license to accelerate the research and development of microscopy foundation models.

Why are Visually-Grounded Language Models Bad at Image Classification?

Image classification is one of the most fundamental capabilities of machine vision intelligence. In this work, we revisit the image classification task using visually-grounded language models (VLMs) such as GPT-4V and LLaVA. We find that existing proprietary and public VLMs, despite often using CLIP as a vision encoder and having many more parameters, significantly underperform CLIP on standard image classification benchmarks like ImageNet. To understand the reason, we explore several hypotheses concerning the inference algorithms, training objectives, and data processing in VLMs. Our analysis reveals that the primary cause is data-related: critical information for image classification is encoded in the VLM's latent space but can only be effectively decoded with enough training data. Specifically, there is a strong correlation between the frequency of class exposure during VLM training and instruction-tuning and the VLM's performance in those classes; when trained with sufficient data, VLMs can match the accuracy of state-of-the-art classification models. Based on these findings, we enhance a VLM by integrating classification-focused datasets into its training, and demonstrate that the enhanced classification performance of the VLM transfers to its general capabilities, resulting in an improvement of 11.8% on the newly collected ImageWikiQA dataset.

Training Small Multimodal Models to Bridge Biomedical Competency Gap: A Case Study in Radiology Imaging

The scaling laws and extraordinary performance of large foundation models motivate the development and utilization of such large models in biomedicine. However, despite early promising results on some biomedical benchmarks, there are still major challenges that need to be addressed before these models can be used in real-world applications. Frontier models such as GPT-4V still have major competency gaps in multimodal capabilities for biomedical applications. Moreover, pragmatic issues such as access, cost, latency, and compliance make it hard for clinicians to use privately-hosted state-of-the-art large models directly on private patient data. In this paper, we explore training open-source small multimodal models (SMMs) to bridge biomedical competency gaps for unmet clinical needs. To maximize data efficiency, we adopt a modular approach by incorporating state-of-the-art pre-trained models for image and text modalities, and focusing on training a lightweight adapter to ground each modality to the text embedding space. We conduct a comprehensive study of this approach on radiology imaging. For training, we assemble a large dataset with over 1 million image-text pairs. For evaluation, we propose a clinically driven novel approach using GPT-4 and demonstrate its parity with expert evaluation. We also study grounding qualitatively using attention. For best practice, we conduct a systematic ablation study on various choices in data engineering and multimodal training. The resulting LLaVA-Rad (7B) model attains state-of-the-art results on radiology tasks such as report generation and cross-modal retrieval, even outperforming much larger models such as GPT-4V and Med-PaLM M (84B). LLaVA-Rad is fast and can be run on a single V100 GPU in private settings, offering a promising state-of-the-art tool for real-world clinical applications.

Depth-guided NeRF Training via Earth Mover's Distance

Neural Radiance Fields (NeRFs) are trained to minimize the rendering loss of predicted viewpoints. However, the photometric loss often does not provide enough information to disambiguate between different possible geometries yielding the same image. Previous work has thus incorporated depth supervision during NeRF training, leveraging dense predictions from pre-trained depth networks as pseudo-ground truth. While these depth priors are assumed to be perfect once filtered for noise, in practice, their accuracy is more challenging to capture. This work proposes a novel approach to uncertainty in depth priors for NeRF supervision. Instead of using custom-trained depth or uncertainty priors, we use off-the-shelf pretrained diffusion models to predict depth and capture uncertainty during the denoising process. Because we know that depth priors are prone to errors, we propose to supervise the ray termination distance distribution with Earth Mover's Distance instead of enforcing the rendered depth to replicate the depth prior exactly through L2-loss. Our depth-guided NeRF outperforms all baselines on standard depth metrics by a large margin while maintaining performance on photometric measures.

Just Shift It: Test-Time Prototype Shifting for Zero-Shot Generalization with Vision-Language Models

Advancements in vision-language models (VLMs) have propelled the field of computer vision, particularly in the zero-shot learning setting. Despite their promise, the effectiveness of these models often diminishes due to domain shifts in test environments. To address this, we introduce the Test-Time Prototype Shifting (TPS) framework, a pioneering approach designed to adapt VLMs to test datasets using unlabeled test inputs. Our method is based on the notion of modulating per-class prototypes in the shared embedding space. By pre-computing and caching prototypes generated with the pre-trained text encoder, TPS not only facilitates optimization-free prototype reuse for subsequent predictions but also enables seamless integration with current advancements in prompt engineering. At test-time, TPS dynamically learns shift vectors for each prototype based solely on the given test sample, effectively bridging the domain gap and enhancing classification accuracy. A notable aspect of our framework is its significantly reduced memory and computational demands when compared to conventional text-prompt tuning methods. Extensive evaluations across 15 datasets involving natural distribution shifts and cross-dataset generalization demonstrate TPS's superior performance, achieving state-of-the-art results while reducing resource requirements.

VideoAgent: Long-form Video Understanding with Large Language Model as Agent

Long-form video understanding represents a significant challenge within computer vision, demanding a model capable of reasoning over long multi-modal sequences. Motivated by the human cognitive process for long-form video understanding, we emphasize interactive reasoning and planning over the ability to process lengthy visual inputs. We introduce a novel agent-based system, VideoAgent, that employs a large language model as a central agent to iteratively identify and compile crucial information to answer a question, with vision-language foundation models serving as tools to translate and retrieve visual information. Evaluated on the challenging EgoSchema and NExT-QA benchmarks, VideoAgent achieves 54.1% and 71.3% zero-shot accuracy with only 8.4 and 8.2 frames used on average. These results demonstrate superior effectiveness and efficiency of our method over the current state-of-the-art methods, highlighting the potential of agent-based approaches in advancing long-form video understanding.