MARIO: A Mixed Annotation Framework For Polyp Segmentation

Existing polyp segmentation models are limited by high labeling costs and the small size of datasets. Additionally, vast polyp datasets remain underutilized because these models typically rely on a single type of annotation. To address this dilemma, we introduce MARIO, a mixed supervision model designed to accommodate various annotation types, significantly expanding the range of usable data. MARIO learns from underutilized datasets by incorporating five forms of supervision: pixel-level, box-level, polygon-level, scribblelevel, and point-level. Each form of supervision is associated with a tailored loss that effectively leverages the supervision labels while minimizing the noise. This allows MARIO to move beyond the constraints of relying on a single annotation type. Furthermore, MARIO primarily utilizes dataset with weak and cheap annotations, reducing the dependence on large-scale, fully annotated ones. Experimental results across five benchmark datasets demonstrate that MARIO consistently outperforms existing methods, highlighting its efficacy in balancing trade-offs between different forms of supervision and maximizing polyp segmentation performance

An LLM-Empowered Adaptive Evolutionary Algorithm For Multi-Component Deep Learning Systems

Multi-objective evolutionary algorithms (MOEAs) are widely used for searching optimal solutions in complex multi-component applications. Traditional MOEAs for multi-component deep learning (MCDL) systems face challenges in enhancing the search efficiency while maintaining the diversity. To combat these, this paper proposes $\mu$MOEA, the first LLM-empowered adaptive evolutionary search algorithm to detect safety violations in MCDL systems. Inspired by the context-understanding ability of Large Language Models (LLMs), $\mu$MOEA promotes the LLM to comprehend the optimization problem and generate an initial population tailed to evolutionary objectives. Subsequently, it employs adaptive selection and variation to iteratively produce offspring, balancing the evolutionary efficiency and diversity. During the evolutionary process, to navigate away from the local optima, $\mu$MOEA integrates the evolutionary experience back into the LLM. This utilization harnesses the LLM's quantitative reasoning prowess to generate differential seeds, breaking away from current optimal solutions. We evaluate $\mu$MOEA in finding safety violations of MCDL systems, and compare its performance with state-of-the-art MOEA methods. Experimental results show that $\mu$MOEA can significantly improve the efficiency and diversity of the evolutionary search.

Generative Semantic Communication for Joint Image Transmission and Segmentation

Semantic communication has emerged as a promising technology for enhancing communication efficiency. However, most existing research emphasizes single-task reconstruction, neglecting model adaptability and generalization across multi-task systems. In this paper, we propose a novel generative semantic communication system that supports both image reconstruction and segmentation tasks. Our approach builds upon semantic knowledge bases (KBs) at both the transmitter and receiver, with each semantic KB comprising a source KB and a task KB. The source KB at the transmitter leverages a hierarchical Swin-Transformer, a generative AI scheme, to extract multi-level features from the input image. Concurrently, the counterpart source KB at the receiver utilizes hierarchical residual blocks to generate task-specific knowledge. Furthermore, the two task KBs adopt a semantic similarity model to map different task requirements into pre-defined task instructions, thereby facilitating the feature selection of the source KBs. Additionally, we develop a unified residual block-based joint source and channel (JSCC) encoder and two task-specific JSCC decoders to achieve the two image tasks. In particular, a generative diffusion model is adopted to construct the JSCC decoder for the image reconstruction task. Experimental results demonstrate that our multi-task generative semantic communication system outperforms previous single-task communication systems in terms of peak signal-to-noise ratio and segmentation accuracy.

Privacy-Preserving Federated Foundation Model for Generalist Ultrasound Artificial Intelligence

Ultrasound imaging is widely used in clinical diagnosis due to its non-invasive nature and real-time capabilities. However, conventional ultrasound diagnostics face several limitations, including high dependence on physician expertise and suboptimal image quality, which complicates interpretation and increases the likelihood of diagnostic errors. Artificial intelligence (AI) has emerged as a promising solution to enhance clinical diagnosis, particularly in detecting abnormalities across various biomedical imaging modalities. Nonetheless, current AI models for ultrasound imaging face critical challenges. First, these models often require large volumes of labeled medical data, raising concerns over patient privacy breaches. Second, most existing models are task-specific, which restricts their broader clinical utility. To overcome these challenges, we present UltraFedFM, an innovative privacy-preserving ultrasound foundation model. UltraFedFM is collaboratively pre-trained using federated learning across 16 distributed medical institutions in 9 countries, leveraging a dataset of over 1 million ultrasound images covering 19 organs and 10 ultrasound modalities. This extensive and diverse data, combined with a secure training framework, enables UltraFedFM to exhibit strong generalization and diagnostic capabilities. It achieves an average area under the receiver operating characteristic curve of 0.927 for disease diagnosis and a dice similarity coefficient of 0.878 for lesion segmentation. Notably, UltraFedFM surpasses the diagnostic accuracy of mid-level ultrasonographers and matches the performance of expert-level sonographers in the joint diagnosis of 8 common systemic diseases. These findings indicate that UltraFedFM can significantly enhance clinical diagnostics while safeguarding patient privacy, marking an advancement in AI-driven ultrasound imaging for future clinical applications.

MixPolyp: Integrating Mask, Box and Scribble Supervision for Enhanced Polyp Segmentation

Limited by the expensive labeling, polyp segmentation models are plagued by data shortages. To tackle this, we propose the mixed supervised polyp segmentation paradigm (MixPolyp). Unlike traditional models relying on a single type of annotation, MixPolyp combines diverse annotation types (mask, box, and scribble) within a single model, thereby expanding the range of available data and reducing labeling costs. To achieve this, MixPolyp introduces three novel supervision losses to handle various annotations: Subspace Projection loss (L_SP), Binary Minimum Entropy loss (L_BME), and Linear Regularization loss (L_LR). For box annotations, L_SP eliminates shape inconsistencies between the prediction and the supervision. For scribble annotations, L_BME provides supervision for unlabeled pixels through minimum entropy constraint, thereby alleviating supervision sparsity. Furthermore, L_LR provides dense supervision by enforcing consistency among the predictions, thus reducing the non-uniqueness. These losses are independent of the model structure, making them generally applicable. They are used only during training, adding no computational cost during inference. Extensive experiments on five datasets demonstrate MixPolyp's effectiveness.

Let Video Teaches You More: Video-to-Image Knowledge Distillation using DEtection TRansformer for Medical Video Lesion Detection

AI-assisted lesion detection models play a crucial role in the early screening of cancer. However, previous image-based models ignore the inter-frame contextual information present in videos. On the other hand, video-based models capture the inter-frame context but are computationally expensive. To mitigate this contradiction, we delve into Video-to-Image knowledge distillation leveraging DEtection TRansformer (V2I-DETR) for the task of medical video lesion detection. V2I-DETR adopts a teacher-student network paradigm. The teacher network aims at extracting temporal contexts from multiple frames and transferring them to the student network, and the student network is an image-based model dedicated to fast prediction in inference. By distilling multi-frame contexts into a single frame, the proposed V2I-DETR combines the advantages of utilizing temporal contexts from video-based models and the inference speed of image-based models. Through extensive experiments, V2I-DETR outperforms previous state-of-the-art methods by a large margin while achieving the real-time inference speed (30 FPS) as the image-based model.

Towards a Benchmark for Colorectal Cancer Segmentation in Endorectal Ultrasound Videos: Dataset and Model Development

Endorectal ultrasound (ERUS) is an important imaging modality that provides high reliability for diagnosing the depth and boundary of invasion in colorectal cancer. However, the lack of a large-scale ERUS dataset with high-quality annotations hinders the development of automatic ultrasound diagnostics. In this paper, we collected and annotated the first benchmark dataset that covers diverse ERUS scenarios, i.e. colorectal cancer segmentation, detection, and infiltration depth staging. Our ERUS-10K dataset comprises 77 videos and 10,000 high-resolution annotated frames. Based on this dataset, we further introduce a benchmark model for colorectal cancer segmentation, named the Adaptive Sparse-context TRansformer (ASTR). ASTR is designed based on three considerations: scanning mode discrepancy, temporal information, and low computational complexity. For generalizing to different scanning modes, the adaptive scanning-mode augmentation is proposed to convert between raw sector images and linear scan ones. For mining temporal information, the sparse-context transformer is incorporated to integrate inter-frame local and global features. For reducing computational complexity, the sparse-context block is introduced to extract contextual features from auxiliary frames. Finally, on the benchmark dataset, the proposed ASTR model achieves a 77.6% Dice score in rectal cancer segmentation, largely outperforming previous state-of-the-art methods.

ScribblePolyp: Scribble-Supervised Polyp Segmentation through Dual Consistency Alignment

Automatic polyp segmentation models play a pivotal role in the clinical diagnosis of gastrointestinal diseases. In previous studies, most methods relied on fully supervised approaches, necessitating pixel-level annotations for model training. However, the creation of pixel-level annotations is both expensive and time-consuming, impeding the development of model generalization. In response to this challenge, we introduce ScribblePolyp, a novel scribble-supervised polyp segmentation framework. Unlike fully-supervised models, ScribblePolyp only requires the annotation of two lines (scribble labels) for each image, significantly reducing the labeling cost. Despite the coarse nature of scribble labels, which leave a substantial portion of pixels unlabeled, we propose a two-branch consistency alignment approach to provide supervision for these unlabeled pixels. The first branch employs transformation consistency alignment to narrow the gap between predictions under different transformations of the same input image. The second branch leverages affinity propagation to refine predictions into a soft version, extending additional supervision to unlabeled pixels. In summary, ScribblePolyp is an efficient model that does not rely on teacher models or moving average pseudo labels during training. Extensive experiments on the SUN-SEG dataset underscore the effectiveness of ScribblePolyp, achieving a Dice score of 0.8155, with the potential for a 1.8% improvement in the Dice score through a straightforward self-training strategy.

WeakPolyp: You Only Look Bounding Box for Polyp Segmentation

Limited by expensive pixel-level labels, polyp segmentation models are plagued by data shortage and suffer from impaired generalization. In contrast, polyp bounding box annotations are much cheaper and more accessible. Thus, to reduce labeling cost, we propose to learn a weakly supervised polyp segmentation model (i.e., WeakPolyp) completely based on bounding box annotations. However, coarse bounding boxes contain too much noise. To avoid interference, we introduce the mask-to-box (M2B) transformation. By supervising the outer box mask of the prediction instead of the prediction itself, M2B greatly mitigates the mismatch between the coarse label and the precise prediction. But, M2B only provides sparse supervision, leading to non-unique predictions. Therefore, we further propose a scale consistency (SC) loss for dense supervision. By explicitly aligning predictions across the same image at different scales, the SC loss largely reduces the variation of predictions. Note that our WeakPolyp is a plug-and-play model, which can be easily ported to other appealing backbones. Besides, the proposed modules are only used during training, bringing no computation cost to inference. Extensive experiments demonstrate the effectiveness of our proposed WeakPolyp, which surprisingly achieves a comparable performance with a fully supervised model, requiring no mask annotations at all.

BoxPolyp:Boost Generalized Polyp Segmentation Using Extra Coarse Bounding Box Annotations

Accurate polyp segmentation is of great importance for colorectal cancer diagnosis and treatment. However, due to the high cost of producing accurate mask annotations, existing polyp segmentation methods suffer from severe data shortage and impaired model generalization. Reversely, coarse polyp bounding box annotations are more accessible. Thus, in this paper, we propose a boosted BoxPolyp model to make full use of both accurate mask and extra coarse box annotations. In practice, box annotations are applied to alleviate the over-fitting issue of previous polyp segmentation models, which generate fine-grained polyp area through the iterative boosted segmentation model. To achieve this goal, a fusion filter sampling (FFS) module is firstly proposed to generate pixel-wise pseudo labels from box annotations with less noise, leading to significant performance improvements. Besides, considering the appearance consistency of the same polyp, an image consistency (IC) loss is designed. Such IC loss explicitly narrows the distance between features extracted by two different networks, which improves the robustness of the model. Note that our BoxPolyp is a plug-and-play model, which can be merged into any appealing backbone. Quantitative and qualitative experimental results on five challenging benchmarks confirm that our proposed model outperforms previous state-of-the-art methods by a large margin.