Structural Entities Extraction and Patient Indications Incorporation for Chest X-ray Report Generation

The automated generation of imaging reports proves invaluable in alleviating the workload of radiologists. A clinically applicable reports generation algorithm should demonstrate its effectiveness in producing reports that accurately describe radiology findings and attend to patient-specific indications. In this paper, we introduce a novel method, \textbf{S}tructural \textbf{E}ntities extraction and patient indications \textbf{I}ncorporation (SEI) for chest X-ray report generation. Specifically, we employ a structural entities extraction (SEE) approach to eliminate presentation-style vocabulary in reports and improve the quality of factual entity sequences. This reduces the noise in the following cross-modal alignment module by aligning X-ray images with factual entity sequences in reports, thereby enhancing the precision of cross-modal alignment and further aiding the model in gradient-free retrieval of similar historical cases. Subsequently, we propose a cross-modal fusion network to integrate information from X-ray images, similar historical cases, and patient-specific indications. This process allows the text decoder to attend to discriminative features of X-ray images, assimilate historical diagnostic information from similar cases, and understand the examination intention of patients. This, in turn, assists in triggering the text decoder to produce high-quality reports. Experiments conducted on MIMIC-CXR validate the superiority of SEI over state-of-the-art approaches on both natural language generation and clinical efficacy metrics.

Multi-scale Information Sharing and Selection Network with Boundary Attention for Polyp Segmentation

Polyp segmentation for colonoscopy images is of vital importance in clinical practice. It can provide valuable information for colorectal cancer diagnosis and surgery. While existing methods have achieved relatively good performance, polyp segmentation still faces the following challenges: (1) Varying lighting conditions in colonoscopy and differences in polyp locations, sizes, and morphologies. (2) The indistinct boundary between polyps and surrounding tissue. To address these challenges, we propose a Multi-scale information sharing and selection network (MISNet) for polyp segmentation task. We design a Selectively Shared Fusion Module (SSFM) to enforce information sharing and active selection between low-level and high-level features, thereby enhancing model's ability to capture comprehensive information. We then design a Parallel Attention Module (PAM) to enhance model's attention to boundaries, and a Balancing Weight Module (BWM) to facilitate the continuous refinement of boundary segmentation in the bottom-up process. Experiments on five polyp segmentation datasets demonstrate that MISNet successfully improved the accuracy and clarity of segmentation result, outperforming state-of-the-art methods.

Factual Serialization Enhancement: A Key Innovation for Chest X-ray Report Generation

The automation of writing imaging reports is a valuable tool for alleviating the workload of radiologists. Crucial steps in this process involve the cross-modal alignment between medical images and reports, as well as the retrieval of similar historical cases. However, the presence of presentation-style vocabulary (e.g., sentence structure and grammar) in reports poses challenges for cross-modal alignment. Additionally, existing methods for similar historical cases retrieval face suboptimal performance owing to the modal gap issue. In response, this paper introduces a novel method, named Factual Serialization Enhancement (FSE), for chest X-ray report generation. FSE begins with the structural entities approach to eliminate presentation-style vocabulary in reports, providing specific input for our model. Then, uni-modal features are learned through cross-modal alignment between images and factual serialization in reports. Subsequently, we present a novel approach to retrieve similar historical cases from the training set, leveraging aligned image features. These features implicitly preserve semantic similarity with their corresponding reference reports, enabling us to calculate similarity solely among aligned features. This effectively eliminates the modal gap issue for knowledge retrieval without the requirement for disease labels. Finally, the cross-modal fusion network is employed to query valuable information from these cases, enriching image features and aiding the text decoder in generating high-quality reports. Experiments on MIMIC-CXR and IU X-ray datasets from both specific and general scenarios demonstrate the superiority of FSE over state-of-the-art approaches in both natural language generation and clinical efficacy metrics.

Region-specific Risk Quantification for Interpretable Prognosis of COVID-19

The COVID-19 pandemic has strained global public health, necessitating accurate diagnosis and intervention to control disease spread and reduce mortality rates. This paper introduces an interpretable deep survival prediction model designed specifically for improved understanding and trust in COVID-19 prognosis using chest X-ray (CXR) images. By integrating a large-scale pretrained image encoder, Risk-specific Grad-CAM, and anatomical region detection techniques, our approach produces regional interpretable outcomes that effectively capture essential disease features while focusing on rare but critical abnormal regions. Our model's predictive results provide enhanced clarity and transparency through risk area localization, enabling clinicians to make informed decisions regarding COVID-19 diagnosis with better understanding of prognostic insights. We evaluate the proposed method on a multi-center survival dataset and demonstrate its effectiveness via quantitative and qualitative assessments, achieving superior C-indexes (0.764 and 0.727) and time-dependent AUCs (0.799 and 0.691). These results suggest that our explainable deep survival prediction model surpasses traditional survival analysis methods in risk prediction, improving interpretability for clinical decision making and enhancing AI system trustworthiness.

Drafting and Revision: Laplacian Pyramid Network for Fast High-Quality Artistic Style Transfer

Artistic style transfer aims at migrating the style from an example image to a content image. Currently, optimization-based methods have achieved great stylization quality, but expensive time cost restricts their practical applications. Meanwhile, feed-forward methods still fail to synthesize complex style, especially when holistic global and local patterns exist. Inspired by the common painting process of drawing a draft and revising the details, we introduce a novel feed-forward method named Laplacian Pyramid Network (LapStyle). LapStyle first transfers global style patterns in low-resolution via a Drafting Network. It then revises the local details in high-resolution via a Revision Network, which hallucinates a residual image according to the draft and the image textures extracted by Laplacian filtering. Higher resolution details can be easily generated by stacking Revision Networks with multiple Laplacian pyramid levels. The final stylized image is obtained by aggregating outputs of all pyramid levels. %We also introduce a patch discriminator to better learn local patterns adversarially. Experiments demonstrate that our method can synthesize high quality stylized images in real time, where holistic style patterns are properly transferred.