Multimodal Information Interaction for Medical Image Segmentation

The use of multimodal data in assisted diagnosis and segmentation has emerged as a prominent area of interest in current research. However, one of the primary challenges is how to effectively fuse multimodal features. Most of the current approaches focus on the integration of multimodal features while ignoring the correlation and consistency between different modal features, leading to the inclusion of potentially irrelevant information. To address this issue, we introduce an innovative Multimodal Information Cross Transformer (MicFormer), which employs a dual-stream architecture to simultaneously extract features from each modality. Leveraging the Cross Transformer, it queries features from one modality and retrieves corresponding responses from another, facilitating effective communication between bimodal features. Additionally, we incorporate a deformable Transformer architecture to expand the search space. We conducted experiments on the MM-WHS dataset, and in the CT-MRI multimodal image segmentation task, we successfully improved the whole-heart segmentation DICE score to 85.57 and MIoU to 75.51. Compared to other multimodal segmentation techniques, our method outperforms by margins of 2.83 and 4.23, respectively. This demonstrates the efficacy of MicFormer in integrating relevant information between different modalities in multimodal tasks. These findings hold significant implications for multimodal image tasks, and we believe that MicFormer possesses extensive potential for broader applications across various domains. Access to our method is available at https://github.com/fxxJuses/MICFormer

Contrastive Prompt Learning-based Code Search based on Interaction Matrix

Code search aims to retrieve the code snippet that highly matches the given query described in natural language. Recently, many code pre-training approaches have demonstrated impressive performance on code search. However, existing code search methods still suffer from two performance constraints: inadequate semantic representation and the semantic gap between natural language (NL) and programming language (PL). In this paper, we propose CPLCS, a contrastive prompt learning-based code search method based on the cross-modal interaction mechanism. CPLCS comprises:(1) PL-NL contrastive learning, which learns the semantic matching relationship between PL and NL representations; (2) a prompt learning design for a dual-encoder structure that can alleviate the problem of inadequate semantic representation; (3) a cross-modal interaction mechanism to enhance the fine-grained mapping between NL and PL. We conduct extensive experiments to evaluate the effectiveness of our approach on a real-world dataset across six programming languages. The experiment results demonstrate the efficacy of our approach in improving semantic representation quality and mapping ability between PL and NL.

Three-Dimensional Medical Image Fusion with Deformable Cross-Attention

Multimodal medical image fusion plays an instrumental role in several areas of medical image processing, particularly in disease recognition and tumor detection. Traditional fusion methods tend to process each modality independently before combining the features and reconstructing the fusion image. However, this approach often neglects the fundamental commonalities and disparities between multimodal information. Furthermore, the prevailing methodologies are largely confined to fusing two-dimensional (2D) medical image slices, leading to a lack of contextual supervision in the fusion images and subsequently, a decreased information yield for physicians relative to three-dimensional (3D) images. In this study, we introduce an innovative unsupervised feature mutual learning fusion network designed to rectify these limitations. Our approach incorporates a Deformable Cross Feature Blend (DCFB) module that facilitates the dual modalities in discerning their respective similarities and differences. We have applied our model to the fusion of 3D MRI and PET images obtained from 660 patients in the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset. Through the application of the DCFB module, our network generates high-quality MRI-PET fusion images. Experimental results demonstrate that our method surpasses traditional 2D image fusion methods in performance metrics such as Peak Signal to Noise Ratio (PSNR) and Structural Similarity Index Measure (SSIM). Importantly, the capacity of our method to fuse 3D images enhances the information available to physicians and researchers, thus marking a significant step forward in the field. The code will soon be available online.

QUIZ: An Arbitrary Volumetric Point Matching Method for Medical Image Registration

Rigid pre-registration involving local-global matching or other large deformation scenarios is crucial. Current popular methods rely on unsupervised learning based on grayscale similarity, but under circumstances where different poses lead to varying tissue structures, or where image quality is poor, these methods tend to exhibit instability and inaccuracies. In this study, we propose a novel method for medical image registration based on arbitrary voxel point of interest matching, called query point quizzer (QUIZ). QUIZ focuses on the correspondence between local-global matching points, specifically employing CNN for feature extraction and utilizing the Transformer architecture for global point matching queries, followed by applying average displacement for local image rigid transformation. We have validated this approach on a large deformation dataset of cervical cancer patients, with results indicating substantially smaller deviations compared to state-of-the-art methods. Remarkably, even for cross-modality subjects, it achieves results surpassing the current state-of-the-art.