Detecting Neurocognitive Disorders through Analyses of Topic Evolution and Cross-modal Consistency in Visual-Stimulated Narratives

Early detection of neurocognitive disorders (NCDs) is crucial for timely intervention and disease management. Speech analysis offers a non-intrusive and scalable screening method, particularly through narrative tasks in neuropsychological assessment tools. Traditional narrative analysis often focuses on local indicators in microstructure, such as word usage and syntax. While these features provide insights into language production abilities, they often fail to capture global narrative patterns, or microstructures. Macrostructures include coherence, thematic organization, and logical progressions, reflecting essential cognitive skills potentially critical for recognizing NCDs. Addressing this gap, we propose to investigate specific cognitive and linguistic challenges by analyzing topical shifts, temporal dynamics, and the coherence of narratives over time, aiming to reveal cognitive deficits by identifying narrative impairments, and exploring their impact on communication and cognition. The investigation is based on the CU-MARVEL Rabbit Story corpus, which comprises recordings of a story-telling task from 758 older adults. We developed two approaches: the Dynamic Topic Models (DTM)-based temporal analysis to examine the evolution of topics over time, and the Text-Image Temporal Alignment Network (TITAN) to evaluate the coherence between spoken narratives and visual stimuli. DTM-based approach validated the effectiveness of dynamic topic consistency as a macrostructural metric (F1=0.61, AUC=0.78). The TITAN approach achieved the highest performance (F1=0.72, AUC=0.81), surpassing established microstructural and macrostructural feature sets. Cross-comparison and regression tasks further demonstrated the effectiveness of proposed dynamic macrostructural modeling approaches for NCD detection.

Not All Errors Are Equal: Investigation of Speech Recognition Errors in Alzheimer's Disease Detection

Automatic Speech Recognition (ASR) plays an important role in speech-based automatic detection of Alzheimer's disease (AD). However, recognition errors could propagate downstream, potentially impacting the detection decisions. Recent studies have revealed a non-linear relationship between word error rates (WER) and AD detection performance, where ASR transcriptions with notable errors could still yield AD detection accuracy equivalent to that based on manual transcriptions. This work presents a series of analyses to explore the effect of ASR transcription errors in BERT-based AD detection systems. Our investigation reveals that not all ASR errors contribute equally to detection performance. Certain words, such as stopwords, despite constituting a large proportion of errors, are shown to play a limited role in distinguishing AD. In contrast, the keywords related to diagnosis tasks exhibit significantly greater importance relative to other words. These findings provide insights into the interplay between ASR errors and the downstream detection model.

Devising a Set of Compact and Explainable Spoken Language Feature for Screening Alzheimer's Disease

Alzheimer's disease (AD) has become one of the most significant health challenges in an aging society. The use of spoken language-based AD detection methods has gained prevalence due to their scalability due to their scalability. Based on the Cookie Theft picture description task, we devised an explainable and effective feature set that leverages the visual capabilities of a large language model (LLM) and the Term Frequency-Inverse Document Frequency (TF-IDF) model. Our experimental results show that the newly proposed features consistently outperform traditional linguistic features across two different classifiers with high dimension efficiency. Our new features can be well explained and interpreted step by step which enhance the interpretability of automatic AD screening.

Purple-teaming LLMs with Adversarial Defender Training

Existing efforts in safeguarding LLMs are limited in actively exposing the vulnerabilities of the target LLM and readily adapting to newly emerging safety risks. To address this, we present Purple-teaming LLMs with Adversarial Defender training (PAD), a pipeline designed to safeguard LLMs by novelly incorporating the red-teaming (attack) and blue-teaming (safety training) techniques. In PAD, we automatically collect conversational data that cover the vulnerabilities of an LLM around specific safety risks in a self-play manner, where the attacker aims to elicit unsafe responses and the defender generates safe responses to these attacks. We then update both modules in a generative adversarial network style by training the attacker to elicit more unsafe responses and updating the defender to identify them and explain the unsafe reason. Experimental results demonstrate that PAD significantly outperforms existing baselines in both finding effective attacks and establishing a robust safe guardrail. Furthermore, our findings indicate that PAD excels in striking a balance between safety and overall model quality. We also reveal key challenges in safeguarding LLMs, including defending multi-turn attacks and the need for more delicate strategies to identify specific risks.

Rethinking Machine Ethics -- Can LLMs Perform Moral Reasoning through the Lens of Moral Theories?

Making moral judgments is an essential step toward developing ethical AI systems. Prevalent approaches are mostly implemented in a bottom-up manner, which uses a large set of annotated data to train models based on crowd-sourced opinions about morality. These approaches have been criticized for potentially overgeneralizing a limited group of annotators' moral stances and lacking explainability. In contrast, top-down approaches make moral judgments grounded in a set of principles. However, it remains conceptual due to the incapability of previous language models and the unsolved debate among moral principles. In this study, we propose a flexible framework to steer Large Language Models (LLMs) to perform moral reasoning with well-established moral theories from interdisciplinary research. The theory-guided top-down framework can incorporate various moral theories. Our experiments demonstrate the effectiveness of the proposed framework on datasets derived from moral theories. Furthermore, we show the alignment between different moral theories and existing morality datasets. Our analysis exhibits the potentials and flaws in existing resources (models and datasets) in developing explainable moral judgment-making systems.

Leveraging Pretrained Representations with Task-related Keywords for Alzheimer's Disease Detection

With the global population aging rapidly, Alzheimer's disease (AD) is particularly prominent in older adults, which has an insidious onset and leads to a gradual, irreversible deterioration in cognitive domains (memory, communication, etc.). Speech-based AD detection opens up the possibility of widespread screening and timely disease intervention. Recent advances in pre-trained models motivate AD detection modeling to shift from low-level features to high-level representations. This paper presents several efficient methods to extract better AD-related cues from high-level acoustic and linguistic features. Based on these features, the paper also proposes a novel task-oriented approach by modeling the relationship between the participants' description and the cognitive task. Experiments are carried out on the ADReSS dataset in a binary classification setup, and models are evaluated on the unseen test set. Results and comparison with recent literature demonstrate the efficiency and superior performance of proposed acoustic, linguistic and task-oriented methods. The findings also show the importance of semantic and syntactic information, and feasibility of automation and generalization with the promising audio-only and task-oriented methods for the AD detection task.

Improving Rare Words Recognition through Homophone Extension and Unified Writing for Low-resource Cantonese Speech Recognition

Homophone characters are common in tonal syllable-based languages, such as Mandarin and Cantonese. The data-intensive end-to-end Automatic Speech Recognition (ASR) systems are more likely to mis-recognize homophone characters and rare words under low-resource settings. For the problem of lowresource Cantonese speech recognition, this paper presents a novel homophone extension method to integrate human knowledge of the homophone lexicon into the beam search decoding process with language model re-scoring. Besides, we propose an automatic unified writing method to merge the variants of Cantonese characters and standardize speech annotation guidelines, which enables more efficient utilization of labeled utterances by providing more samples for the merged characters. We empirically show that both homophone extension and unified writing improve the recognition performance significantly on both in-domain and out-of-domain test sets, with an absolute Character Error Rate (CER) decrease of around 5% and 18%.