Abstract:In medical image segmentation, personalized cross-silo federated learning (FL) is becoming popular for utilizing varied data across healthcare settings to overcome data scarcity and privacy concerns. However, existing methods often suffer from client drift, leading to inconsistent performance and delayed training. We propose a new framework, Personalized Federated Learning via Feature Enhancement (pFLFE), designed to mitigate these challenges. pFLFE consists of two main stages: feature enhancement and supervised learning. The first stage improves differentiation between foreground and background features, and the second uses these enhanced features for learning from segmentation masks. We also design an alternative training approach that requires fewer communication rounds without compromising segmentation quality, even with limited communication resources. Through experiments on three medical segmentation tasks, we demonstrate that pFLFE outperforms the state-of-the-art methods.
Abstract:In the evolving application of medical artificial intelligence, federated learning is notable for its ability to protect training data privacy. Federated learning facilitates collaborative model development without the need to share local data from healthcare institutions. Yet, the statistical and system heterogeneity among these institutions poses substantial challenges, which affects the effectiveness of federated learning and hampers the exchange of information between clients. To address these issues, we introduce a novel approach, MH-pFLGB, which employs a global bypass strategy to mitigate the reliance on public datasets and navigate the complexities of non-IID data distributions. Our method enhances traditional federated learning by integrating a global bypass model, which would share the information among the clients, but also serves as part of the network to enhance the performance on each client. Additionally, MH-pFLGB provides a feature fusion module to better combine the local and global features. We validate \model{}'s effectiveness and adaptability through extensive testing on different medical tasks, demonstrating superior performance compared to existing state-of-the-art methods.
Abstract:Text-to-image diffusion models have achieved tremendous success in the field of controllable image generation, while also coming along with issues of privacy leakage and data copyrights. Membership inference arises in these contexts as a potential auditing method for detecting unauthorized data usage. While some efforts have been made on diffusion models, they are not applicable to text-to-image diffusion models due to the high computation overhead and enhanced generalization capabilities. In this paper, we first identify a conditional overfitting phenomenon in text-to-image diffusion models, indicating that these models tend to overfit the conditional distribution of images given the text rather than the marginal distribution of images. Based on this observation, we derive an analytical indicator, namely Conditional Likelihood Discrepancy (CLiD), to perform membership inference. This indicator reduces the stochasticity in estimating the memorization of individual samples. Experimental results demonstrate that our method significantly outperforms previous methods across various data distributions and scales. Additionally, our method shows superior resistance to overfitting mitigation strategies such as early stopping and data augmentation.
Abstract:Federated learning is widely used in medical applications for training global models without needing local data access. However, varying computational capabilities and network architectures (system heterogeneity), across clients pose significant challenges in effectively aggregating information from non-independently and identically distributed (non-IID) data. Current federated learning methods using knowledge distillation require public datasets, raising privacy and data collection issues. Additionally, these datasets require additional local computing and storage resources, which is a burden for medical institutions with limited hardware conditions. In this paper, we introduce a novel federated learning paradigm, named Model Heterogeneous personalized Federated Learning via Injection and Distillation (MH-pFLID). Our framework leverages a lightweight messenger model that carries concentrated information to collect the information from each client. We also develop a set of receiver and transmitter modules to receive and send information from the messenger model, so that the information could be injected and distilled with efficiency.
Abstract:Recently text-to-image models have gained widespread attention in the community due to their controllable and high-quality generation ability. However, the robustness of such models and their potential ethical issues have not been fully explored. In this paper, we introduce Universal Semantic Trigger, a meaningless token sequence that can be added at any location within the input text yet can induce generated images towards a preset semantic target.To thoroughly investigate it, we propose Semantic Gradient-based Search (SGS) framework. SGS automatically discovers the potential universal semantic triggers based on the given semantic targets. Furthermore, we design evaluation metrics to comprehensively evaluate semantic shift of images caused by these triggers. And our empirical analyses reveal that the mainstream open-source text-to-image models are vulnerable to our triggers, which could pose significant ethical threats. Our work contributes to a further understanding of text-to-image synthesis and helps users to automatically auditing their models before deployment.
Abstract:Representation learning frameworks in unlabeled time series have been proposed for medical signal processing. Despite the numerous excellent progresses have been made in previous works, we observe the representation extracted for the time series still does not generalize well. In this paper, we present a Time series (medical signal) Representation Learning framework via Spectrogram (TRLS) to get more informative representations. We transform the input time-domain medical signals into spectrograms and design a time-frequency encoder named Time Frequency RNN (TFRNN) to capture more robust multi-scale representations from the augmented spectrograms. Our TRLS takes spectrogram as input with two types of different data augmentations and maximizes the similarity between positive ones, which effectively circumvents the problem of designing negative samples. Our evaluation of four real-world medical signal datasets focusing on medical signal classification shows that TRLS is superior to the existing frameworks.
Abstract:The rapid identification and accurate diagnosis of breast cancer, known as the killer of women, have become greatly significant for those patients. Numerous breast cancer histopathological image classification methods have been proposed. But they still suffer from two problems. (1) These methods can only hand high-resolution (HR) images. However, the low-resolution (LR) images are often collected by the digital slide scanner with limited hardware conditions. Compared with HR images, LR images often lose some key features like texture, which deeply affects the accuracy of diagnosis. (2) The existing methods have fixed receptive fields, so they can not extract and fuse multi-scale features well for images with different magnification factors. To fill these gaps, we present a \textbf{S}ingle \textbf{H}istopathological \textbf{I}mage \textbf{S}uper-\textbf{R}esolution \textbf{C}lassification network (SHISRCNet), which consists of two modules: Super-Resolution (SR) and Classification (CF) modules. SR module reconstructs LR images into SR ones. CF module extracts and fuses the multi-scale features of SR images for classification. In the training stage, we introduce HR images into the CF module to enhance SHISRCNet's performance. Finally, through the joint training of these two modules, super-resolution and classified of LR images are integrated into our model. The experimental results demonstrate that the effects of our method are close to the SOTA methods with taking HR images as inputs.
Abstract:With the help of conditioning mechanisms, the state-of-the-art diffusion models have achieved tremendous success in guided image generation, particularly in text-to-image synthesis. To gain a better understanding of the training process and potential risks of text-to-image synthesis, we perform a systematic investigation of backdoor attack on text-to-image diffusion models and propose BadT2I, a general multimodal backdoor attack framework that tampers with image synthesis in diverse semantic levels. Specifically, we perform backdoor attacks on three levels of the vision semantics: Pixel-Backdoor, Object-Backdoor and Style-Backdoor. By utilizing a regularization loss, our methods efficiently inject backdoors into a large-scale text-to-image diffusion model while preserving its utility with benign inputs. We conduct empirical experiments on Stable Diffusion, the widely-used text-to-image diffusion model, demonstrating that the large-scale diffusion model can be easily backdoored within a few fine-tuning steps. We conduct additional experiments to explore the impact of different types of textual triggers. Besides, we discuss the backdoor persistence during further training, the findings of which provide insights for the development of backdoor defense methods.
Abstract:At present, backdoor attacks attract attention as they do great harm to deep learning models. The adversary poisons the training data making the model being injected with a backdoor after being trained unconsciously by victims using the poisoned dataset. In the field of text, however, existing works do not provide sufficient defense against backdoor attacks. In this paper, we propose a Noise-augmented Contrastive Learning (NCL) framework to defend against textual backdoor attacks when training models with untrustworthy data. With the aim of mitigating the mapping between triggers and the target label, we add appropriate noise perturbing possible backdoor triggers, augment the training dataset, and then pull homology samples in the feature space utilizing contrastive learning objective. Experiments demonstrate the effectiveness of our method in defending three types of textual backdoor attacks, outperforming the prior works.
Abstract:Although Deep Neural Network (DNN) has led to unprecedented progress in various natural language processing (NLP) tasks, research shows that deep models are extremely vulnerable to backdoor attacks. The existing backdoor attacks mainly inject a small number of poisoned samples into the training dataset with the labels changed to the target one. Such mislabeled samples would raise suspicion upon human inspection, potentially revealing the attack. To improve the stealthiness of textual backdoor attacks, we propose the first clean-label framework Kallima for synthesizing mimesis-style backdoor samples to develop insidious textual backdoor attacks. We modify inputs belonging to the target class with adversarial perturbations, making the model rely more on the backdoor trigger. Our framework is compatible with most existing backdoor triggers. The experimental results on three benchmark datasets demonstrate the effectiveness of the proposed method.