$χ$-sepnet: Deep neural network for magnetic susceptibility source separation

Magnetic susceptibility source separation ($\chi$-separation), an advanced quantitative susceptibility mapping (QSM) method, enables the separate estimation of para- and diamagnetic susceptibility source distributions in the brain. The method utilizes reversible transverse relaxation (R2'=R2*-R2) to complement frequency shift information for estimating susceptibility source concentrations, requiring time-consuming data acquisition for R2 in addition R2*. To address this challenge, we develop a new deep learning network, $\chi$-sepnet, and propose two deep learning-based susceptibility source separation pipelines, $\chi$-sepnet-R2' for inputs with multi-echo GRE and multi-echo spin-echo, and $\chi$-sepnet-R2* for input with multi-echo GRE only. $\chi$-sepnet is trained using multiple head orientation data that provide streaking artifact-free labels, generating high-quality $\chi$-separation maps. The evaluation of the pipelines encompasses both qualitative and quantitative assessments in healthy subjects, and visual inspection of lesion characteristics in multiple sclerosis patients. The susceptibility source-separated maps of the proposed pipelines delineate detailed brain structures with substantially reduced artifacts compared to those from conventional regularization-based reconstruction methods. In quantitative analysis, $\chi$-sepnet-R2' achieves the best outcomes followed by $\chi$-sepnet-R2*, outperforming the conventional methods. When the lesions of multiple sclerosis patients are assessed, both pipelines report identical lesion characteristics in most lesions ($\chi$para: 99.6% and $\chi$dia: 98.4% out of 250 lesions). The $\chi$-sepnet-R2* pipeline, which only requires multi-echo GRE data, has demonstrated its potential to offer broad clinical and scientific applications, although further evaluations for various diseases and pathological conditions are necessary.

Soft Segmented Randomization: Enhancing Domain Generalization in SAR-ATR for Synthetic-to-Measured

Synthetic aperture radar technology is crucial for high-resolution imaging under various conditions; however, the acquisition of real-world synthetic aperture radar data for deep learning-based automatic target recognition remains challenging due to high costs and data availability issues. To overcome these challenges, synthetic data generated through simulations have been employed, although discrepancies between synthetic and real data can degrade model performance. In this study, we introduce a novel framework, soft segmented randomization, designed to reduce domain discrepancy and improve the generalize ability of synthetic aperture radar automatic target recognition models. The soft segmented randomization framework applies a Gaussian mixture model to segment target and clutter regions softly, introducing randomized variations that align the synthetic data's statistical properties more closely with those of real-world data. Experimental results demonstrate that the proposed soft segmented randomization framework significantly enhances model performance on measured synthetic aperture radar data, making it a promising approach for robust automatic target recognition in scenarios with limited or no access to measured data.

X-LLaVA: Optimizing Bilingual Large Vision-Language Alignment

The impressive development of large language models (LLMs) is expanding into the realm of large multimodal models (LMMs), which incorporate multiple types of data beyond text. However, the nature of multimodal models leads to significant expenses in the creation of training data. Furthermore, constructing multilingual data for LMMs presents its own set of challenges due to language diversity and complexity. Therefore, in this study, we propose two cost-effective methods to solve this problem: (1) vocabulary expansion and pretraining of multilingual LLM for specific languages, and (2) automatic and elaborate construction of multimodal datasets using GPT4-V. Based on015 these methods, we constructed a 91K English-Korean-Chinese multilingual, multimodal training dataset. Additionally, we developed a bilingual multimodal model that exhibits excellent performance in both Korean and English, surpassing existing approaches.

BOK-VQA: Bilingual Outside Knowledge-based Visual Question Answering via Graph Representation Pretraining

The current research direction in generative models, such as the recently developed GPT4, aims to find relevant knowledge information for multimodal and multilingual inputs to provide answers. Under these research circumstances, the demand for multilingual evaluation of visual question answering (VQA) tasks, a representative task of multimodal systems, has increased. Accordingly, we propose a bilingual outside-knowledge VQA (BOK-VQA) dataset in this study that can be extended to multilingualism. The proposed data include 17K images, 17K question-answer pairs for both Korean and English and 280K instances of knowledge information related to question-answer content. We also present a framework that can effectively inject knowledge information into a VQA system by pretraining the knowledge information of BOK-VQA data in the form of graph embeddings. Finally, through in-depth analysis, we demonstrated the actual effect of the knowledge information contained in the constructed training data on VQA.

A human brain atlas of chi-separation for normative iron and myelin distributions

Iron and myelin are primary susceptibility sources in the human brain. These substances are essential for healthy brain, and their abnormalities are often related to various neurological disorders. Recently, an advanced susceptibility mapping technique, which is referred to as chi-separation, has been proposed successfully disentangling paramagnetic iron from diamagnetic myelin, opening a new potential for generating iron map and myelin map in the brain. Utilizing this technique, this study constructs a normative chi-separation atlas from 106 healthy human brains. The resulting atlas provides detailed anatomical structures associated with the distributions of iron and myelin, clearly delineating subcortical nuclei and white matter fiber bundles. Additionally, susceptibility values in a number of regions of interest are reported along with age-dependent changes. This atlas may have direct applications such as localization of subcortical structures for deep brain stimulation or high-intensity focused ultrasound and also serve as a valuable resource for future research.

Coil2Coil: Self-supervised MR image denoising using phased-array coil images

Denoising of magnetic resonance images is beneficial in improving the quality of low signal-to-noise ratio images. Recently, denoising using deep neural networks has demonstrated promising results. Most of these networks, however, utilize supervised learning, which requires large training images of noise-corrupted and clean image pairs. Obtaining training images, particularly clean images, is expensive and time-consuming. Hence, methods such as Noise2Noise (N2N) that require only pairs of noise-corrupted images have been developed to reduce the burden of obtaining training datasets. In this study, we propose a new self-supervised denoising method, Coil2Coil (C2C), that does not require the acquisition of clean images or paired noise-corrupted images for training. Instead, the method utilizes multichannel data from phased-array coils to generate training images. First, it divides and combines multichannel coil images into two images, one for input and the other for label. Then, they are processed to impose noise independence and sensitivity normalization such that they can be used for the training images of N2N. For inference, the method inputs a coil-combined image (e.g., DICOM image), enabling a wide application of the method. When evaluated using synthetic noise-added images, C2C shows the best performance against several self-supervised methods, reporting comparable outcomes to supervised methods. When testing the DICOM images, C2C successfully denoised real noise without showing structure-dependent residuals in the error maps. Because of the significant advantage of not requiring additional scans for clean or paired images, the method can be easily utilized for various clinical applications.

Neuro CROSS exchange: Learning to CROSS exchange to solve realistic vehicle routing problems

CROSS exchange (CE), a meta-heuristic that solves various vehicle routing problems (VRPs), improves the solutions of VRPs by swapping the sub-tours of the vehicles. Inspired by CE, we propose Neuro CE (NCE), a fundamental operator of learned meta-heuristic, to solve various VRPs while overcoming the limitations of CE (i.e., the expensive $\mathcal{O}(n^4)$ search cost). NCE employs a graph neural network to predict the cost-decrements (i.e., results of CE searches) and utilizes the predicted cost-decrements as guidance for search to decrease the search cost to $\mathcal{O}(n^2)$. As the learning objective of NCE is to predict the cost-decrement, the training can be simply done in a supervised fashion, whose training samples can be prepared effortlessly. Despite the simplicity of NCE, numerical results show that the NCE trained with flexible multi-depot VRP (FMDVRP) outperforms the meta-heuristic baselines. More importantly, it significantly outperforms the neural baselines when solving distinctive special cases of FMDVRP (e.g., MDVRP, mTSP, CVRP) without additional training.

Capturing the Production of the Innovative Ideas: An Online Social Network Experiment and "Idea Geography" Visualization

Collective design and innovation are crucial in organizations. To investigate how the collective design and innovation processes would be affected by the diversity of knowledge and background of collective individual members, we conducted three collaborative design task experiments which involved nearly 300 participants who worked together anonymously in a social network structure using a custom-made computer-mediated collaboration platform. We compared the idea generation activity among three different background distribution conditions (clustered, random, and dispersed) with the help of the "doc2vec" text representation machine learning algorithm. We also developed a new method called "Idea Geography" to visualize the idea utility terrain on a 2D problem domain. The results showed that groups with random background allocation tended to produce the best design idea with highest utility values. It was also suggested that the diversity of participants' backgrounds distribution on the network might interact with each other to affect the diversity of ideas generated. The proposed idea geography successfully visualized that the collective design processes did find the high utility area through exploration and exploitation in collaborative work.

The Power of Communities: A Text Classification Model with Automated Labeling Process Using Network Community Detection

The text classification is one of the most critical areas in machine learning and artificial intelligence research. It has been actively adopted in many business applications such as conversational intelligence systems, news articles categorizations, sentiment analysis, emotion detection systems, and many other recommendation systems in our daily life. One of the problems in supervised text classification models is that the models performance depend heavily on the quality of data labeling that are typically done by humans. In this study, we propose a new network community detection-based approach to automatically label and classify text data into multiclass value spaces. Specifically, we build a network with sentences as the network nodes and pairwise cosine similarities between TFIDF vector representations of the sentences as the network link weights. We use the Louvain method to detect the communities in the sentence network. We train and test Support vector machine and Random forest models on both the human labeled data and network community detection labeled data. Results showed that models with the data labeled by network community detection outperformed the models with the human-labeled data by 2.68-3.75% of classification accuracy. Our method may help development of a more accurate conversational intelligence system and other text classification systems.