ABC3: Active Bayesian Causal Inference with Cohn Criteria in Randomized Experiments

In causal inference, randomized experiment is a de facto method to overcome various theoretical issues in observational study. However, the experimental design requires expensive costs, so an efficient experimental design is necessary. We propose ABC3, a Bayesian active learning policy for causal inference. We show a policy minimizing an estimation error on conditional average treatment effect is equivalent to minimizing an integrated posterior variance, similar to Cohn criteria \citep{cohn1994active}. We theoretically prove ABC3 also minimizes an imbalance between the treatment and control groups and the type 1 error probability. Imbalance-minimizing characteristic is especially notable as several works have emphasized the importance of achieving balance. Through extensive experiments on real-world data sets, ABC3 achieves the highest efficiency, while empirically showing the theoretical results hold.

Pre-trained Language Models Return Distinguishable Probability Distributions to Unfaithfully Hallucinated Texts

In this work, we show the pre-trained language models return distinguishable generation probability and uncertainty distribution to unfaithfully hallucinated texts, regardless of their size and structure. By examining 24 models on 6 data sets, we find out that 88-98% of cases return statistically significantly distinguishable generation probability and uncertainty distributions. Using this general phenomenon, we showcase a hallucination-reducing training algorithm. Our algorithm outperforms other baselines by achieving higher faithfulness metrics while maintaining sound general text quality measures.

Block Orthogonal Sparse Superposition Codes for $ \sf{L}^3 $ Communications: Low Error Rate, Low Latency, and Low Power Consumption

Block orthogonal sparse superposition (BOSS) code is a class of joint coded modulation methods, which can closely achieve the finite-blocklength capacity with a low-complexity decoder at a few coding rates under Gaussian channels. However, for fading channels, the code performance degrades considerably because coded symbols experience different channel fading effects. In this paper, we put forth novel joint demodulation and decoding methods for BOSS codes under fading channels. For a fast fading channel, we present a minimum mean square error approximate maximum a posteriori (MMSE-A-MAP) algorithm for the joint demodulation and decoding when channel state information is available at the receiver (CSIR). We also propose a joint demodulation and decoding method without using CSIR for a block fading channel scenario. We refer to this as the non-coherent sphere decoding (NSD) algorithm. Simulation results demonstrate that BOSS codes with MMSE-A-MAP decoding outperform CRC-aided polar codes, while NSD decoding achieves comparable performance to quasi-maximum likelihood decoding with significantly reduced complexity. Both decoding algorithms are suitable for parallelization, satisfying low-latency constraints. Additionally, real-time simulations on a software-defined radio testbed validate the feasibility of using BOSS codes for low-power transmission.

P5: Plug-and-Play Persona Prompting for Personalized Response Selection

The use of persona-grounded retrieval-based chatbots is crucial for personalized conversations, but there are several challenges that need to be addressed. 1) In general, collecting persona-grounded corpus is very expensive. 2) The chatbot system does not always respond in consideration of persona at real applications. To address these challenges, we propose a plug-and-play persona prompting method. Our system can function as a standard open-domain chatbot if persona information is not available. We demonstrate that this approach performs well in the zero-shot setting, which reduces the dependence on persona-ground training data. This makes it easier to expand the system to other languages without the need to build a persona-grounded corpus. Additionally, our model can be fine-tuned for even better performance. In our experiments, the zero-shot model improved the standard model by 7.71 and 1.04 points in the original persona and revised persona, respectively. The fine-tuned model improved the previous state-of-the-art system by 1.95 and 3.39 points in the original persona and revised persona, respectively. To the best of our knowledge, this is the first attempt to solve the problem of personalized response selection using prompt sequences. Our code is available on github~\footnote{https://github.com/rungjoo/plug-and-play-prompt-persona}.

Virchow: A Million-Slide Digital Pathology Foundation Model

Computational pathology uses artificial intelligence to enable precision medicine and decision support systems through the analysis of whole slide images. It has the potential to revolutionize the diagnosis and treatment of cancer. However, a major challenge to this objective is that for many specific computational pathology tasks the amount of data is inadequate for development. To address this challenge, we created Virchow, a 632 million parameter deep neural network foundation model for computational pathology. Using self-supervised learning, Virchow is trained on 1.5 million hematoxylin and eosin stained whole slide images from diverse tissue groups, which is orders of magnitude more data than previous works. When evaluated on downstream tasks including tile-level pan-cancer detection and subtyping and slide-level biomarker prediction, Virchow outperforms state-of-the-art systems both on internal datasets drawn from the same population as the pretraining data as well as external public datasets. Virchow achieves 93% balanced accuracy for pancancer tile classification, and AUCs of 0.983 for colon microsatellite instability status prediction and 0.967 for breast CDH1 status prediction. The gains in performance highlight the importance of pretraining on massive pathology image datasets, suggesting pretraining on even larger datasets could continue improving performance for many high-impact applications where limited amounts of training data are available, such as drug outcome prediction.

Truly Batch Apprenticeship Learning with Deep Successor Features

We introduce a novel apprenticeship learning algorithm to learn an expert's underlying reward structure in off-policy model-free \emph{batch} settings. Unlike existing methods that require a dynamics model or additional data acquisition for on-policy evaluation, our algorithm requires only the batch data of observed expert behavior. Such settings are common in real-world tasks---health care, finance or industrial processes ---where accurate simulators do not exist or data acquisition is costly. To address challenges in batch settings, we introduce Deep Successor Feature Networks(DSFN) that estimate feature expectations in an off-policy setting and a transition-regularized imitation network that produces a near-expert initial policy and an efficient feature representation. Our algorithm achieves superior results in batch settings on both control benchmarks and a vital clinical task of sepsis management in the Intensive Care Unit.

Evaluating Reinforcement Learning Algorithms in Observational Health Settings

Much attention has been devoted recently to the development of machine learning algorithms with the goal of improving treatment policies in healthcare. Reinforcement learning (RL) is a sub-field within machine learning that is concerned with learning how to make sequences of decisions so as to optimize long-term effects. Already, RL algorithms have been proposed to identify decision-making strategies for mechanical ventilation, sepsis management and treatment of schizophrenia. However, before implementing treatment policies learned by black-box algorithms in high-stakes clinical decision problems, special care must be taken in the evaluation of these policies. In this document, our goal is to expose some of the subtleties associated with evaluating RL algorithms in healthcare. We aim to provide a conceptual starting point for clinical and computational researchers to ask the right questions when designing and evaluating algorithms for new ways of treating patients. In the following, we describe how choices about how to summarize a history, variance of statistical estimators, and confounders in more ad-hoc measures can result in unreliable, even misleading estimates of the quality of a treatment policy. We also provide suggestions for mitigating these effects---for while there is much promise for mining observational health data to uncover better treatment policies, evaluation must be performed thoughtfully.

Deep Learning on Key Performance Indicators for Predictive Maintenance in SAP HANA

With a new era of cloud and big data, Database Management Systems (DBMSs) have become more crucial in numerous enterprise business applications in all the industries. Accordingly, the importance of their proactive and preventive maintenance has also increased. However, detecting problems by predefined rules or stochastic modeling has limitations, particularly when analyzing the data on high-dimensional Key Performance Indicators (KPIs) from a DBMS. In recent years, Deep Learning (DL) has opened new opportunities for this complex analysis. In this paper, we present two complementary DL approaches to detect anomalies in SAP HANA. A temporal learning approach is used to detect abnormal patterns based on unlabeled historical data, whereas a spatial learning approach is used to classify known anomalies based on labeled data. We implement a system in SAP HANA integrated with Google TensorFlow. The experimental results with real-world data confirm the effectiveness of the system and models.