MSCPT: Few-shot Whole Slide Image Classification with Multi-scale and Context-focused Prompt Tuning

Multiple instance learning (MIL) has become a standard paradigm for weakly supervised classification of whole slide images (WSI). However, this paradigm relies on the use of a large number of labelled WSIs for training. The lack of training data and the presence of rare diseases present significant challenges for these methods. Prompt tuning combined with the pre-trained Vision-Language models (VLMs) is an effective solution to the Few-shot Weakly Supervised WSI classification (FSWC) tasks. Nevertheless, applying prompt tuning methods designed for natural images to WSIs presents three significant challenges: 1) These methods fail to fully leverage the prior knowledge from the VLM's text modality; 2) They overlook the essential multi-scale and contextual information in WSIs, leading to suboptimal results; and 3) They lack exploration of instance aggregation methods. To address these problems, we propose a Multi-Scale and Context-focused Prompt Tuning (MSCPT) method for FSWC tasks. Specifically, MSCPT employs the frozen large language model to generate pathological visual language prior knowledge at multi-scale, guiding hierarchical prompt tuning. Additionally, we design a graph prompt tuning module to learn essential contextual information within WSI, and finally, a non-parametric cross-guided instance aggregation module has been introduced to get the WSI-level features. Based on two VLMs, extensive experiments and visualizations on three datasets demonstrated the powerful performance of our MSCPT.

ARFA: An Asymmetric Receptive Field Autoencoder Model for Spatiotemporal Prediction

Spatiotemporal prediction aims to generate future sequences by paradigms learned from historical contexts. It holds significant importance in numerous domains, including traffic flow prediction and weather forecasting. However, existing methods face challenges in handling spatiotemporal correlations, as they commonly adopt encoder and decoder architectures with identical receptive fields, which adversely affects prediction accuracy. This paper proposes an Asymmetric Receptive Field Autoencoder (ARFA) model to address this issue. Specifically, we design corresponding sizes of receptive field modules tailored to the distinct functionalities of the encoder and decoder. In the encoder, we introduce a large kernel module for global spatiotemporal feature extraction. In the decoder, we develop a small kernel module for local spatiotemporal information reconstruction. To address the scarcity of meteorological prediction data, we constructed the RainBench, a large-scale radar echo dataset specific to the unique precipitation characteristics of inland regions in China for precipitation prediction. Experimental results demonstrate that ARFA achieves consistent state-of-the-art performance on two mainstream spatiotemporal prediction datasets and our RainBench dataset, affirming the effectiveness of our approach. This work not only explores a novel method from the perspective of receptive fields but also provides data support for precipitation prediction, thereby advancing future research in spatiotemporal prediction.

Towards Simultaneous Segmentation of Liver Tumors and Intrahepatic Vessels via Cross-attention Mechanism

Accurate visualization of liver tumors and their surrounding blood vessels is essential for noninvasive diagnosis and prognosis prediction of tumors. In medical image segmentation, there is still a lack of in-depth research on the simultaneous segmentation of liver tumors and peritumoral blood vessels. To this end, we collect the first liver tumor, and vessel segmentation benchmark datasets containing 52 portal vein phase computed tomography images with liver, liver tumor, and vessel annotations. In this case, we propose a 3D U-shaped Cross-Attention Network (UCA-Net) that utilizes a tailored cross-attention mechanism instead of the traditional skip connection to effectively model the encoder and decoder feature. Specifically, the UCA-Net uses a channel-wise cross-attention module to reduce the semantic gap between encoder and decoder and a slice-wise cross-attention module to enhance the contextual semantic learning ability among distinct slices. Experimental results show that the proposed UCA-Net can accurately segment 3D medical images and achieve state-of-the-art performance on the liver tumor and intrahepatic vessel segmentation task.

Are We Ready For Learned Cardinality Estimation?

Cardinality estimation is a fundamental but long unresolved problem in query optimization. Recently, multiple papers from different research groups consistently report that learned models have the potential to replace existing cardinality estimators. In this paper, we ask a forward-thinking question: Are we ready to deploy these learned cardinality models in production? Our study consists of three main parts. Firstly, we focus on the static environment (i.e., no data updates) and compare five new learned methods with eight traditional methods on four real-world datasets under a unified workload setting. The results show that learned models are indeed more accurate than traditional methods, but they often suffer from high training and inference costs. Secondly, we explore whether these learned models are ready for dynamic environments (i.e., frequent data updates). We find that they cannot catch up with fast data up-dates and return large errors for different reasons. For less frequent updates, they can perform better but there is no clear winner among themselves. Thirdly, we take a deeper look into learned models and explore when they may go wrong. Our results show that the performance of learned methods can be greatly affected by the changes in correlation, skewness, or domain size. More importantly, their behaviors are much harder to interpret and often unpredictable. Based on these findings, we identify two promising research directions (control the cost of learned models and make learned models trustworthy) and suggest a number of research opportunities. We hope that our study can guide researchers and practitioners to work together to eventually push learned cardinality estimators into real database systems.