Hybrid deep learning-based strategy for the hepatocellular carcinoma cancer grade classification of H&E stained liver histopathology images

Hepatocellular carcinoma (HCC) is a common type of liver cancer whose early-stage diagnosis is a common challenge, mainly due to the manual assessment of hematoxylin and eosin-stained whole slide images, which is a time-consuming process and may lead to variability in decision-making. For accurate detection of HCC, we propose a hybrid deep learning-based architecture that uses transfer learning to extract the features from pre-trained convolutional neural network (CNN) models and a classifier made up of a sequence of fully connected layers. This study uses a publicly available The Cancer Genome Atlas Hepatocellular Carcinoma (TCGA-LIHC)database (n=491) for model development and database of Kasturba Gandhi Medical College (KMC), India for validation. The pre-processing step involves patch extraction, colour normalization, and augmentation that results in 3920 patches for the TCGA dataset. The developed hybrid deep neural network consisting of a CNN-based pre-trained feature extractor and a customized artificial neural network-based classifier is trained using five-fold cross-validation. For this study, eight different state-of-the-art models are trained and tested as feature extractors for the proposed hybrid model. The proposed hybrid model with ResNet50-based feature extractor provided the sensitivity, specificity, F1-score, accuracy, and AUC of 100.00%, 100.00%, 100.00%, 100.00%, and 1.00, respectively on the TCGA database. On the KMC database, EfficientNetb3 resulted in the optimal choice of the feature extractor giving sensitivity, specificity, F1-score, accuracy, and AUC of 96.97, 98.85, 96.71, 96.71, and 0.99, respectively. The proposed hybrid models showed improvement in accuracy of 2% and 4% over the pre-trained models in TCGA-LIHC and KMC databases.

FoodMem: Near Real-time and Precise Food Video Segmentation

Food segmentation, including in videos, is vital for addressing real-world health, agriculture, and food biotechnology issues. Current limitations lead to inaccurate nutritional analysis, inefficient crop management, and suboptimal food processing, impacting food security and public health. Improving segmentation techniques can enhance dietary assessments, agricultural productivity, and the food production process. This study introduces the development of a robust framework for high-quality, near-real-time segmentation and tracking of food items in videos, using minimal hardware resources. We present FoodMem, a novel framework designed to segment food items from video sequences of 360-degree unbounded scenes. FoodMem can consistently generate masks of food portions in a video sequence, overcoming the limitations of existing semantic segmentation models, such as flickering and prohibitive inference speeds in video processing contexts. To address these issues, FoodMem leverages a two-phase solution: a transformer segmentation phase to create initial segmentation masks and a memory-based tracking phase to monitor food masks in complex scenes. Our framework outperforms current state-of-the-art food segmentation models, yielding superior performance across various conditions, such as camera angles, lighting, reflections, scene complexity, and food diversity. This results in reduced segmentation noise, elimination of artifacts, and completion of missing segments. Here, we also introduce a new annotated food dataset encompassing challenging scenarios absent in previous benchmarks. Extensive experiments conducted on Nutrition5k and Vegetables & Fruits datasets demonstrate that FoodMem enhances the state-of-the-art by 2.5% mean average precision in food video segmentation and is 58 x faster on average.

MetaFood CVPR 2024 Challenge on Physically Informed 3D Food Reconstruction: Methods and Results

The increasing interest in computer vision applications for nutrition and dietary monitoring has led to the development of advanced 3D reconstruction techniques for food items. However, the scarcity of high-quality data and limited collaboration between industry and academia have constrained progress in this field. Building on recent advancements in 3D reconstruction, we host the MetaFood Workshop and its challenge for Physically Informed 3D Food Reconstruction. This challenge focuses on reconstructing volume-accurate 3D models of food items from 2D images, using a visible checkerboard as a size reference. Participants were tasked with reconstructing 3D models for 20 selected food items of varying difficulty levels: easy, medium, and hard. The easy level provides 200 images, the medium level provides 30 images, and the hard level provides only 1 image for reconstruction. In total, 16 teams submitted results in the final testing phase. The solutions developed in this challenge achieved promising results in 3D food reconstruction, with significant potential for improving portion estimation for dietary assessment and nutritional monitoring. More details about this workshop challenge and access to the dataset can be found at https://sites.google.com/view/cvpr-metafood-2024.

Precision at Scale: Domain-Specific Datasets On-Demand

In the realm of self-supervised learning (SSL), conventional wisdom has gravitated towards the utility of massive, general domain datasets for pretraining robust backbones. In this paper, we challenge this idea by exploring if it is possible to bridge the scale between general-domain datasets and (traditionally smaller) domain-specific datasets to reduce the current performance gap. More specifically, we propose Precision at Scale (PaS), a novel method for the autonomous creation of domain-specific datasets on-demand. The modularity of the PaS pipeline enables leveraging state-of-the-art foundational and generative models to create a collection of images of any given size belonging to any given domain with minimal human intervention. Extensive analysis in two complex domains, proves the superiority of PaS datasets over existing traditional domain-specific datasets in terms of diversity, scale, and effectiveness in training visual transformers and convolutional neural networks. Most notably, we prove that automatically generated domain-specific datasets lead to better pretraining than large-scale supervised datasets such as ImageNet-1k and ImageNet-21k. Concretely, models trained on domain-specific datasets constructed by PaS pipeline, beat ImageNet-1k pretrained backbones by at least 12% in all the considered domains and classification tasks and lead to better food domain performance than supervised ImageNet-21k pretrain while being 12 times smaller. Code repository: https://github.com/jesusmolrdv/Precision-at-Scale/

MomentsNeRF: Leveraging Orthogonal Moments for Few-Shot Neural Rendering

We propose MomentsNeRF, a novel framework for one- and few-shot neural rendering that predicts a neural representation of a 3D scene using Orthogonal Moments. Our architecture offers a new transfer learning method to train on multi-scenes and incorporate a per-scene optimization using one or a few images at test time. Our approach is the first to successfully harness features extracted from Gabor and Zernike moments, seamlessly integrating them into the NeRF architecture. We show that MomentsNeRF performs better in synthesizing images with complex textures and shapes, achieving a significant noise reduction, artifact elimination, and completing the missing parts compared to the recent one- and few-shot neural rendering frameworks. Extensive experiments on the DTU and Shapenet datasets show that MomentsNeRF improves the state-of-the-art by {3.39\;dB\;PSNR}, 11.1% SSIM, 17.9% LPIPS, and 8.3% DISTS metrics. Moreover, it outperforms state-of-the-art performance for both novel view synthesis and single-image 3D view reconstruction. The source code is accessible at: https://amughrabi.github.io/momentsnerf/.

VolETA: One- and Few-shot Food Volume Estimation

Accurate food volume estimation is essential for dietary assessment, nutritional tracking, and portion control applications. We present VolETA, a sophisticated methodology for estimating food volume using 3D generative techniques. Our approach creates a scaled 3D mesh of food objects using one- or few-RGBD images. We start by selecting keyframes based on the RGB images and then segmenting the reference object in the RGB images using XMem++. Simultaneously, camera positions are estimated and refined using the PixSfM technique. The segmented food images, reference objects, and camera poses are combined to form a data model suitable for NeuS2. Independent mesh reconstructions for reference and food objects are carried out, with scaling factors determined using MeshLab based on the reference object. Moreover, depth information is used to fine-tune the scaling factors by estimating the potential volume range. The fine-tuned scaling factors are then applied to the cleaned food meshes for accurate volume measurements. Similarly, we enter a segmented RGB image to the One-2-3-45 model for one-shot food volume estimation, resulting in a mesh. We then leverage the obtained scaling factors to the cleaned food mesh for accurate volume measurements. Our experiments show that our method effectively addresses occlusions, varying lighting conditions, and complex food geometries, achieving robust and accurate volume estimations with 10.97% MAPE using the MTF dataset. This innovative approach enhances the precision of volume assessments and significantly contributes to computational nutrition and dietary monitoring advancements.

MVSBoost: An Efficient Point Cloud-based 3D Reconstruction

Efficient and accurate 3D reconstruction is crucial for various applications, including augmented and virtual reality, medical imaging, and cinematic special effects. While traditional Multi-View Stereo (MVS) systems have been fundamental in these applications, using neural implicit fields in implicit 3D scene modeling has introduced new possibilities for handling complex topologies and continuous surfaces. However, neural implicit fields often suffer from computational inefficiencies, overfitting, and heavy reliance on data quality, limiting their practical use. This paper presents an enhanced MVS framework that integrates multi-view 360-degree imagery with robust camera pose estimation via Structure from Motion (SfM) and advanced image processing for point cloud densification, mesh reconstruction, and texturing. Our approach significantly improves upon traditional MVS methods, offering superior accuracy and precision as validated using Chamfer distance metrics on the Realistic Synthetic 360 dataset. The developed MVS technique enhances the detail and clarity of 3D reconstructions and demonstrates superior computational efficiency and robustness in complex scene reconstruction, effectively handling occlusions and varying viewpoints. These improvements suggest that our MVS framework can compete with and potentially exceed current state-of-the-art neural implicit field methods, especially in scenarios requiring real-time processing and scalability.

A New Multimodal Medical Image Fusion based on Laplacian Autoencoder with Channel Attention

Medical image fusion combines the complementary information of multimodal medical images to assist medical professionals in the clinical diagnosis of patients' disorders and provide guidance during preoperative and intra-operative procedures. Deep learning (DL) models have achieved end-to-end image fusion with highly robust and accurate fusion performance. However, most DL-based fusion models perform down-sampling on the input images to minimize the number of learnable parameters and computations. During this process, salient features of the source images become irretrievable leading to the loss of crucial diagnostic edge details and contrast of various brain tissues. In this paper, we propose a new multimodal medical image fusion model is proposed that is based on integrated Laplacian-Gaussian concatenation with attention pooling (LGCA). We prove that our model preserves effectively complementary information and important tissue structures.

Multi-modal Medical Neurological Image Fusion using Wavelet Pooled Edge Preserving Autoencoder

Medical image fusion integrates the complementary diagnostic information of the source image modalities for improved visualization and analysis of underlying anomalies. Recently, deep learning-based models have excelled the conventional fusion methods by executing feature extraction, feature selection, and feature fusion tasks, simultaneously. However, most of the existing convolutional neural network (CNN) architectures use conventional pooling or strided convolutional strategies to downsample the feature maps. It causes the blurring or loss of important diagnostic information and edge details available in the source images and dilutes the efficacy of the feature extraction process. Therefore, this paper presents an end-to-end unsupervised fusion model for multimodal medical images based on an edge-preserving dense autoencoder network. In the proposed model, feature extraction is improved by using wavelet decomposition-based attention pooling of feature maps. This helps in preserving the fine edge detail information present in both the source images and enhances the visual perception of fused images. Further, the proposed model is trained on a variety of medical image pairs which helps in capturing the intensity distributions of the source images and preserves the diagnostic information effectively. Substantial experiments are conducted which demonstrate that the proposed method provides improved visual and quantitative results as compared to the other state-of-the-art fusion methods.

Continual Evidential Deep Learning for Out-of-Distribution Detection

Uncertainty-based deep learning models have attracted a great deal of interest for their ability to provide accurate and reliable predictions. Evidential deep learning stands out achieving remarkable performance in detecting out-of-distribution (OOD) data with a single deterministic neural network. Motivated by this fact, in this paper we propose the integration of an evidential deep learning method into a continual learning framework in order to perform simultaneously incremental object classification and OOD detection. Moreover, we analyze the ability of vacuity and dissonance to differentiate between in-distribution data belonging to old classes and OOD data. The proposed method, called CEDL, is evaluated on CIFAR-100 considering two settings consisting of 5 and 10 tasks, respectively. From the obtained results, we could appreciate that the proposed method, in addition to provide comparable results in object classification with respect to the baseline, largely outperforms OOD detection compared to several posthoc methods on three evaluation metrics: AUROC, AUPR and FPR95.