LGU-SLAM: Learnable Gaussian Uncertainty Matching with Deformable Correlation Sampling for Deep Visual SLAM

Deep visual Simultaneous Localization and Mapping (SLAM) techniques, e.g., DROID, have made significant advancements by leveraging deep visual odometry on dense flow fields. In general, they heavily rely on global visual similarity matching. However, the ambiguous similarity interference in uncertain regions could often lead to excessive noise in correspondences, ultimately misleading SLAM in geometric modeling. To address this issue, we propose a Learnable Gaussian Uncertainty (LGU) matching. It mainly focuses on precise correspondence construction. In our scheme, a learnable 2D Gaussian uncertainty model is designed to associate matching-frame pairs. It could generate input-dependent Gaussian distributions for each correspondence map. Additionally, a multi-scale deformable correlation sampling strategy is devised to adaptively fine-tune the sampling of each direction by a priori look-up ranges, enabling reliable correlation construction. Furthermore, a KAN-bias GRU component is adopted to improve a temporal iterative enhancement for accomplishing sophisticated spatio-temporal modeling with limited parameters. The extensive experiments on real-world and synthetic datasets are conducted to validate the effectiveness and superiority of our method.

Queryable Prototype Multiple Instance Learning with Vision-Language Models for Incremental Whole Slide Image Classification

Whole Slide Image (WSI) classification has very significant applications in clinical pathology, e.g., tumor identification and cancer diagnosis. Currently, most research attention is focused on Multiple Instance Learning (MIL) using static datasets. One of the most obvious weaknesses of these methods is that they cannot efficiently preserve and utilize previously learned knowledge. With any new data arriving, classification models are required to be re-trained on both previous and current new data. To overcome this shortcoming and break through traditional vision modality, this paper proposes the first Vision-Language-based framework with Queryable Prototype Multiple Instance Learning (QPMIL-VL) specially designed for incremental WSI classification. This framework mainly consists of two information processing branches. One is for generating the bag-level feature by prototype-guided aggregating on the instance features. While the other is for enhancing the class feature through class ensemble, tunable vector and class similarity loss. The experiments on four TCGA datasets demonstrate that our QPMIL-VL framework is effective for incremental WSI classification and often significantly outperforms other compared methods, achieving state-of-the-art (SOTA) performance.

Interpretable Vision-Language Survival Analysis with Ordinal Inductive Bias for Computational Pathology

Histopathology Whole-Slide Images (WSIs) provide an important tool to assess cancer prognosis in computational pathology (CPATH). While existing survival analysis (SA) approaches have made exciting progress, they are generally limited to adopting highly-expressive architectures and only coarse-grained patient-level labels to learn prognostic visual representations from gigapixel WSIs. Such learning paradigm suffers from important performance bottlenecks, when facing present scarce training data and standard multi-instance learning (MIL) framework in CPATH. To break through it, this paper, for the first time, proposes a new Vision-Language-based SA (VLSA) paradigm. Concretely, (1) VLSA is driven by pathology VL foundation models. It no longer relies on high-capability networks and shows the advantage of data efficiency. (2) In vision-end, VLSA encodes prognostic language prior and then employs it as auxiliary signals to guide the aggregating of prognostic visual features at instance level, thereby compensating for the weak supervision in MIL. Moreover, given the characteristics of SA, we propose i) ordinal survival prompt learning to transform continuous survival labels into textual prompts; and ii) ordinal incidence function as prediction target to make SA compatible with VL-based prediction. VLSA's predictions can be interpreted intuitively by our Shapley values-based method. The extensive experiments on five datasets confirm the effectiveness of our scheme. Our VLSA could pave a new way for SA in CPATH by offering weakly-supervised MIL an effective means to learn valuable prognostic clues from gigapixel WSIs. Our source code is available at https://github.com/liupei101/VLSA.

Deformable Feature Alignment and Refinement for Moving Infrared Dim-small Target Detection

The detection of moving infrared dim-small targets has been a challenging and prevalent research topic. The current state-of-the-art methods are mainly based on ConvLSTM to aggregate information from adjacent frames to facilitate the detection of the current frame. However, these methods implicitly utilize motion information only in the training stage and fail to explicitly explore motion compensation, resulting in poor performance in the case of a video sequence including large motion. In this paper, we propose a Deformable Feature Alignment and Refinement (DFAR) method based on deformable convolution to explicitly use motion context in both the training and inference stages. Specifically, a Temporal Deformable Alignment (TDA) module based on the designed Dilated Convolution Attention Fusion (DCAF) block is developed to explicitly align the adjacent frames with the current frame at the feature level. Then, the feature refinement module adaptively fuses the aligned features and further aggregates useful spatio-temporal information by means of the proposed Attention-guided Deformable Fusion (AGDF) block. In addition, to improve the alignment of adjacent frames with the current frame, we extend the traditional loss function by introducing a new motion compensation loss. Extensive experimental results demonstrate that the proposed DFAR method achieves the state-of-the-art performance on two benchmark datasets including DAUB and IRDST.

Triple-domain Feature Learning with Frequency-aware Memory Enhancement for Moving Infrared Small Target Detection

Moving infrared small target detection presents significant challenges due to tiny target sizes and low contrast against backgrounds. Currently-existing methods primarily focus on extracting target features only from the spatial-temporal domain. For further enhancing feature representation, more information domains such as frequency are believed to be potentially valuable. To extend target feature learning, we propose a new Triple-domain Strategy (Tridos) with the frequency-aware memory enhancement on the spatial-temporal domain. In our scheme, it effectively detaches and enhances frequency features by a local-global frequency-aware module with Fourier transform. Inspired by the human visual system, our memory enhancement aims to capture the target spatial relations between video frames. Furthermore, it encodes temporal dynamics motion features via differential learning and residual enhancing. Additionally, we further design a residual compensation unit to reconcile possible cross-domain feature mismatches. To our best knowledge, our Tridos is the first work to explore target feature learning comprehensively in spatial-temporal-frequency domains. The extensive experiments on three datasets (DAUB, ITSDT-15K, and IRDST) validate that our triple-domain learning scheme could be obviously superior to state-of-the-art ones. Source codes are available at https://github.com/UESTC-nnLab/Tridos.

Weakly-Supervised Residual Evidential Learning for Multi-Instance Uncertainty Estimation

Uncertainty estimation (UE), as an effective means of quantifying predictive uncertainty, is crucial for safe and reliable decision-making, especially in high-risk scenarios. Existing UE schemes usually assume that there are completely-labeled samples to support fully-supervised learning. In practice, however, many UE tasks often have no sufficiently-labeled data to use, such as the Multiple Instance Learning (MIL) with only weak instance annotations. To bridge this gap, this paper, for the first time, addresses the weakly-supervised issue of Multi-Instance UE (MIUE) and proposes a new baseline scheme, Multi-Instance Residual Evidential Learning (MIREL). Particularly, at the fine-grained instance UE with only weak supervision, we derive a multi-instance residual operator through the Fundamental Theorem of Symmetric Functions. On this operator derivation, we further propose MIREL to jointly model the high-order predictive distribution at bag and instance levels for MIUE. Extensive experiments empirically demonstrate that our MIREL not only could often make existing MIL networks perform better in MIUE, but also could surpass representative UE methods by large margins, especially in instance-level UE tasks.

Pseudo-Bag Mixup Augmentation for Multiple Instance Learning-Based Whole Slide Image Classification

Given the special situation of modeling gigapixel images, multiple instance learning (MIL) has become one of the most important frameworks for Whole Slide Image (WSI) classification. In current practice, most MIL networks often face two unavoidable problems in training: i) insufficient WSI data, and ii) the sample memorization inclination inherent in neural networks. These problems may hinder MIL models from adequate and efficient training, suppressing the continuous performance promotion of classification models on WSIs. Inspired by the basic idea of Mixup, this paper proposes a new Pseudo-bag Mixup (PseMix) data augmentation scheme to improve the training of MIL models. This scheme generalizes the Mixup strategy for general images to special WSIs via pseudo-bags so as to be applied in MIL-based WSI classification. Cooperated by pseudo-bags, our PseMix fulfills the critical size alignment and semantic alignment in Mixup strategy. Moreover, it is designed as an efficient and decoupled method, neither involving time-consuming operations nor relying on MIL model predictions. Comparative experiments and ablation studies are specially designed to evaluate the effectiveness and advantages of our PseMix. Experimental results show that PseMix could often assist state-of-the-art MIL networks to refresh the classification performance on WSIs. Besides, it could also boost the generalization ability of MIL models, and promote their robustness to patch occlusion and noisy labels. Our source code is available at https://github.com/liupei101/PseMix.

ProtoDiv: Prototype-guided Division of Consistent Pseudo-bags for Whole-slide Image Classification

Due to the limitations of inadequate Whole-Slide Image (WSI) samples with weak labels, pseudo-bag-based multiple instance learning (MIL) appears as a vibrant prospect in WSI classification. However, the pseudo-bag dividing scheme, often crucial for classification performance, is still an open topic worth exploring. Therefore, this paper proposes a novel scheme, ProtoDiv, using a bag prototype to guide the division of WSI pseudo-bags. Rather than designing complex network architecture, this scheme takes a plugin-and-play approach to safely augment WSI data for effective training while preserving sample consistency. Furthermore, we specially devise an attention-based prototype that could be optimized dynamically in training to adapt to a classification task. We apply our ProtoDiv scheme on seven baseline models, and then carry out a group of comparison experiments on two public WSI datasets. Experiments confirm our ProtoDiv could usually bring obvious performance improvements to WSI classification.

Shared Coupling-bridge for Weakly Supervised Local Feature Learning

Sparse local feature extraction is usually believed to be of important significance in typical vision tasks such as simultaneous localization and mapping, image matching and 3D reconstruction. At present, it still has some deficiencies needing further improvement, mainly including the discrimination power of extracted local descriptors, the localization accuracy of detected keypoints, and the efficiency of local feature learning. This paper focuses on promoting the currently popular sparse local feature learning with camera pose supervision. Therefore, it pertinently proposes a Shared Coupling-bridge scheme with four light-weight yet effective improvements for weakly-supervised local feature (SCFeat) learning. It mainly contains: i) the \emph{Feature-Fusion-ResUNet Backbone} (F2R-Backbone) for local descriptors learning, ii) a shared coupling-bridge normalization to improve the decoupling training of description network and detection network, iii) an improved detection network with peakiness measurement to detect keypoints and iv) the fundamental matrix error as a reward factor to further optimize feature detection training. Extensive experiments prove that our SCFeat improvement is effective. It could often obtain a state-of-the-art performance on classic image matching and visual localization. In terms of 3D reconstruction, it could still achieve competitive results. For sharing and communication, our source codes are available at https://github.com/sunjiayuanro/SCFeat.git.

AdvMIL: Adversarial Multiple Instance Learning for the Survival Analysis on Whole-Slide Images

The survival analysis on histological whole-slide images (WSIs) is one of the most important means to estimate patient prognosis. Although many weakly-supervised deep learning models have been developed for gigapixel WSIs, their potential is generally restricted by classical survival analysis rules and fully-supervision requirements. As a result, these models provide patients only with a completely-certain point estimation of time-to-event, and they could only learn from the well-annotated WSI data currently at a small scale. To tackle these problems, we propose a novel adversarial multiple instance learning (AdvMIL) framework. This framework is based on adversarial time-to-event modeling, and it integrates the multiple instance learning (MIL) that is much necessary for WSI representation learning. It is a plug-and-play one, so that most existing WSI-based models with embedding-level MIL networks can be easily upgraded by applying this framework, gaining the improved ability of survival distribution estimation and semi-supervised learning. Our extensive experiments show that AdvMIL could not only bring performance improvement to mainstream WSI models at a relatively low computational cost, but also enable these models to learn from unlabeled data with semi-supervised learning. Our AdvMIL framework could promote the research of time-to-event modeling in computational pathology with its novel paradigm of adversarial MIL.