Abstract:Multi-view learning methods often focus on improving decision accuracy, while neglecting the decision uncertainty, limiting their suitability for safety-critical applications. To mitigate this, researchers propose trusted multi-view learning methods that estimate classification probabilities and uncertainty by learning the class distributions for each instance. However, these methods assume that the data from each view can effectively differentiate all categories, ignoring the semantic vagueness phenomenon in real-world multi-view data. Our findings demonstrate that this phenomenon significantly suppresses the learning of view-specific evidence in existing methods. We propose a Consistent and Complementary-aware trusted Multi-view Learning (CCML) method to solve this problem. We first construct view opinions using evidential deep neural networks, which consist of belief mass vectors and uncertainty estimates. Next, we dynamically decouple the consistent and complementary evidence. The consistent evidence is derived from the shared portions across all views, while the complementary evidence is obtained by averaging the differing portions across all views. We ensure that the opinion constructed from the consistent evidence strictly aligns with the ground-truth category. For the opinion constructed from the complementary evidence, we allow it for potential vagueness in the evidence. We compare CCML with state-of-the-art baselines on one synthetic and six real-world datasets. The results validate the effectiveness of the dynamic evidence decoupling strategy and show that CCML significantly outperforms baselines on accuracy and reliability. The code is released at https://github.com/Lihong-Liu/CCML.
Abstract:Accurate segmentation of lung cancer in pathology slides is a critical step in improving patient care. We proposed the ACDC@LungHP (Automatic Cancer Detection and Classification in Whole-slide Lung Histopathology) challenge for evaluating different computer-aided diagnosis (CADs) methods on the automatic diagnosis of lung cancer. The ACDC@LungHP 2019 focused on segmentation (pixel-wise detection) of cancer tissue in whole slide imaging (WSI), using an annotated dataset of 150 training images and 50 test images from 200 patients. This paper reviews this challenge and summarizes the top 10 submitted methods for lung cancer segmentation. All methods were evaluated using the false positive rate, false negative rate, and DICE coefficient (DC). The DC ranged from 0.7354$\pm$0.1149 to 0.8372$\pm$0.0858. The DC of the best method was close to the inter-observer agreement (0.8398$\pm$0.0890). All methods were based on deep learning and categorized into two groups: multi-model method and single model method. In general, multi-model methods were significantly better ($\textit{p}$<$0.01$) than single model methods, with mean DC of 0.7966 and 0.7544, respectively. Deep learning based methods could potentially help pathologists find suspicious regions for further analysis of lung cancer in WSI.